Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 361 to 372 of 372 entries
Sorted by: Best Match Show Resources per page
Inheritance of pheromone profiles from aged .

microPublication biology

Brown SG, Brenman-Suttner DB, McInnes AG, Lew K, Moehring AJ, Bauer JH, Simon AF.
PMID: 34723148
MicroPubl Biol. 2021 Oct 11;2021. doi: 10.17912/micropub.biology.000459. eCollection 2021.

Through aging,

Safety of vaccination against SARS-CoV-2 in people with rheumatic and musculoskeletal diseases: results from the EULAR Coronavirus Vaccine (COVAX) physician-reported registry.

Annals of the rheumatic diseases

Machado PM, Lawson-Tovey S, Strangfeld A, Mateus EF, Hyrich KL, Gossec L, Carmona L, Rodrigues A, Raffeiner B, Duarte C, Hachulla E, Veillard E, Strakova E, Burmester GR, Yardımcı GK, Gomez-Puerta JA, Zepa J, Kearsley-Fleet L, Trefond L, Cunha M, Mosca M, Cornalba M, Soubrier M, Roux N, Brocq O, Durez P, Conway R, Goulenok T, Bijlsma JW, McInnes IB, Mariette X.
PMID: 34972811
Ann Rheum Dis. 2021 Dec 31; doi: 10.1136/annrheumdis-2021-221490. Epub 2021 Dec 31.

OBJECTIVES: To describe the safety of vaccines against SARS-CoV-2 in people with inflammatory/autoimmune rheumatic and musculoskeletal disease (I-RMD).METHODS: Physician-reported registry of I-RMD and non-inflammatory RMD (NI-RMDs) patients vaccinated against SARS-CoV-2. From 5 February 2021 to 27 July 2021, we...

Radiative balance and temperature of differently pigmented cotton canopies.

International journal of biometeorology

Carvalho HDR, McInnes KJ, Heilman JL, Maeda MM.
PMID: 34988681
Int J Biometeorol. 2022 Jan 06; doi: 10.1007/s00484-021-02221-x. Epub 2022 Jan 06.

Pigments are known to modify the spectral properties of foliage, which in turn affect the amount of radiant energy stored by the plant canopy. Studies have shown that red pigments (anthocyanin) increase leaf absorptivity of solar radiation, but little...

Atomically Dispersed Copper Sites in a Metal-Organic Framework for Reduction of Nitrogen Dioxide.

Journal of the American Chemical Society

Ma Y, Han X, Xu S, Wang Z, Li W, da Silva I, Chansai S, Lee D, Zou Y, Nikiel M, Manuel P, Sheveleva AM, Tuna F, McInnes EJL, Cheng Y, Rudić S, Ramirez-Cuesta AJ, Haigh SJ, Hardacre C, Schröder M, Yang S.
PMID: 34279096
J Am Chem Soc. 2021 Jul 28;143(29):10977-10985. doi: 10.1021/jacs.1c03036. Epub 2021 Jul 19.

Metal-organic framework (MOF) materials provide an excellent platform to fabricate single-atom catalysts due to their structural diversity, intrinsic porosity, and designable functionality. However, the unambiguous identification of atomically dispersed metal sites and the elucidation of their role in catalysis...

Secukinumab for the treatment of psoriasis, psoriatic arthritis, and axial spondyloarthritis: Physical and pharmacological properties underlie the observed clinical efficacy and safety.

Pharmacology & therapeutics

Kolbinger F, Di Padova F, Deodhar A, Hawkes JE, Huppertz C, Kuiper T, McInnes IB, Ritchlin CT, Rosmarin D, Schett G, Carballido JM, Häusermann P, Calonder C, Vogel B, Rondeau JM, Bruin G.
PMID: 34171337
Pharmacol Ther. 2022 Jan;229:107925. doi: 10.1016/j.pharmthera.2021.107925. Epub 2021 Jun 23.

Psoriasis, psoriatic arthritis, and axial spondyloarthritis are systemic inflammatory diseases, each commonly manifesting as a spectrum of symptoms, complications, and comorbidities that arise differently in individual patients. Drugs targeting inflammatory cytokines common to the pathogenesis of each of these...

Novel self-amplificatory loop between T cells and tenocytes as a driver of chronicity in tendon disease.

Annals of the rheumatic diseases

Garcia-Melchor E, Cafaro G, MacDonald L, Crowe LAN, Sood S, McLean M, Fazzi UG, McInnes IB, Akbar M, Millar NL.
PMID: 33692018
Ann Rheum Dis. 2021 Mar 10; doi: 10.1136/annrheumdis-2020-219335. Epub 2021 Mar 10.

OBJECTIVES: Increasing evidence suggests that inflammatory mechanisms play a key role in chronic tendon disease. After observing T cell signatures in human tendinopathy, we explored the interaction between T cells and tendon stromal cells or tenocytes to define their...

Targeting synovial fibroblast proliferation in rheumatoid arthritis (TRAFIC): an open-label, dose-finding, phase 1b trial.

The Lancet. Rheumatology

Pratt AG, Siebert S, Cole M, Stocken DD, Yap C, Kelly S, Shaikh M, Cranston A, Morton M, Walker J, Frame S, Ng WF, Buckley CD, McInnes IB, Filer A, Isaacs JD.
PMID: 33928262
Lancet Rheumatol. 2021 Mar 09;3(5):e337-e346. doi: 10.1016/S2665-9913(21)00061-8. eCollection 2021 May.

BACKGROUND: Current rheumatoid arthritis therapies target immune inflammation and are subject to ceiling effects. Seliciclib is an orally available cyclin-dependent kinase inhibitor that suppresses proliferation of synovial fibroblasts-cells not yet targeted in rheumatoid arthritis. Part 1 of this phase...

Long-term Efficacy and Safety of Guselkumab, a Monoclonal Antibody Specific to the p19 Subunit of Interleukin-23, Through 2 Years: Results from a Phase 3, Randomized, Double-blind, Placebo-controlled Study Conducted in Biologic-naïve Patients with Active Psoriatic Arthritis.

Arthritis & rheumatology (Hoboken, N.J.)

McInnes IB, Rahman P, Gottlieb AB, Hsia EC, Kollmeier AP, Xu XL, Jiang Y, Sheng S, Shawi M, Chakravarty SD, van der Heijde D, Mease PJ.
PMID: 34719872
Arthritis Rheumatol. 2021 Nov 01; doi: 10.1002/art.42010. Epub 2021 Nov 01.

OBJECTIVE: Assess long-term efficacy and safety of guselkumab, an IL-23p19-subunit inhibitor, in patients with active psoriatic arthritis (PsA) from the Phase-3 DISCOVER-2 trial.METHODS: In DISCOVER-2, patients with active PsA (≥5 swollen and ≥5 tender joints; CRP ≥0.6 mg/dL) despite...

Apremilast Inhibits Inflammatory Osteoclastogenesis.

Rheumatology (Oxford, England)

Degboé Y, Sunzini F, Sood S, Bozec A, Sokolova MV, Zekovic A, McInnes IB, Schett G, Goodyear CS.
PMID: 33788924
Rheumatology (Oxford). 2021 Mar 31; doi: 10.1093/rheumatology/keab315. Epub 2021 Mar 31.

BACKGROUND: Psoriatic arthritis (PsA) is associated with bone erosion and inflammation-induced bone loss, which are mediated by osteoclasts and modulated by inflammatory cytokines. Apremilast (a selective phosphodiesterase 4 inhibitor) is efficacious in PsA and acts by inhibiting cytokine production....

Immune-mediated inflammatory disease therapeutics: past, present and future.

Nature reviews. Immunology

McInnes IB, Gravallese EM.
PMID: 34518662
Nat Rev Immunol. 2021 Oct;21(10):680-686. doi: 10.1038/s41577-021-00603-1. Epub 2021 Sep 13.

Immune-mediated inflammatory diseases are common and clinically diverse. Although they are currently incurable, the therapeutic armamentarium for immune-mediated inflammatory diseases has been transformed in the past two decades. We have moved from the wide application of broad-spectrum immune modulators...

IL-23 orchestrating immune cell activation in arthritis.

Rheumatology (Oxford, England)

Najm A, McInnes IB.
PMID: 34668017
Rheumatology (Oxford). 2021 Oct 19;60:iv4-iv15. doi: 10.1093/rheumatology/keab266.

IL-23 is a cytokine member of the IL-12 superfamily. These heterodimeric cytokines offer broad immune regulatory activity with potential effector function in inflammatory arthritis. IL-23 is a pro-inflammatory cytokine secreted by dendritic cells and macrophages. It plays a key...

Pseudo-data generation for the extraction of Problems, Treatments and Tests.

AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science

Smith J, French E, Cramer W, Uzuner Ӧ, McInnes BT.
PMID: 34457173
AMIA Jt Summits Transl Sci Proc. 2021 May 17;2021:575-584. eCollection 2021.

One of the primary challenges for clinical Named Entity Recognition (NER) is the availability of annotated training data. Technical and legal hurdles prevent the creation and release of corpora related to electronic health records (EHRs). In this work, we...

Showing 361 to 372 of 372 entries