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Showing 289 to 300 of 300 entries
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Evaluation of COVID-19 vaccine breakthrough infections among immunocompromised patients fully vaccinated with BNT162b2.

Journal of medical economics

Di Fusco M, Moran MM, Cane A, Curcio D, Khan F, Malhotra D, Surinach A, Miles A, Swerdlow D, McLaughlin JM, Nguyen JL.
PMID: 34844493
J Med Econ. 2021 Jan-Dec;24(1):1248-1260. doi: 10.1080/13696998.2021.2002063.

OBJECTIVE: To evaluate COVID-19 vaccine breakthrough infections among immunocompromised (IC) individuals.METHODS: Individuals vaccinated with BNT162b2 were selected from the US HealthVerity database (10 December 2020RESULTS: Of 1,277,747 individuals ≥16 years of age who received 2 BNT162b2 doses, 225,796 (17.7%)...

Remote OSCE Experience: What First Year Pharmacy Students Liked, Learned, and Suggested for Future Implementations.

Pharmacy (Basel, Switzerland)

Savage A, Minshew LM, Anksorus HN, McLaughlin JE.
PMID: 33803696
Pharmacy (Basel). 2021 Mar 18;9(1). doi: 10.3390/pharmacy9010062.

During the wake of the COVID-19 pandemic, many schools quickly transitioned their teaching and assessment strategies to online formats. In Spring 2020, a 3-station remote Objective Structured Clinical Examination (OSCE) was implemented for first-year pharmacy students. The day following...

Beyond the usual suspects: methanogenic communities in eastern North American peatlands are also influenced by nickel and copper concentrations.

FEMS microbiology letters

Bear SE, Seward JD, Lamit LJ, Basiliko N, Moore T, Lilleskov E, Yavitt JB, Schadt CW, Smith DS, Mclaughlin J, Siljanen H, Mykytczuk N, Williams S, Roulet N, Harris L, Carson MA, Watmough S, Bräuer SL.
PMID: 34875049
FEMS Microbiol Lett. 2021 Dec 24;368(21). doi: 10.1093/femsle/fnab151.

Peatlands both accumulate carbon and release methane, but their broad range in environmental conditions means that the diversity of microorganisms responsible for carbon cycling is still uncertain. Here, we describe a community analysis of methanogenic archaea responsible for methane...

Respiratory Syncytial Virus-Associated Hospitalization Rates among US Infants: A Systematic Review and Meta-Analysis.

The Journal of infectious diseases

McLaughlin JM, Khan F, Schmitt HJ, Agosti Y, Jodar L, Simões EAF, Swerdlow DL.
PMID: 33346360
J Infect Dis. 2020 Dec 21; doi: 10.1093/infdis/jiaa752. Epub 2020 Dec 21.

BACKGROUND: Although global reviews of infant RSV burden exist, none have summarized data from the United States or evaluated how RSV burden estimates are influenced by variations in study design.METHODS: We performed a systematic literature review and meta-analysis of...

Does the ability to identify the construct on an empathy situational judgment test relate to performance? Exploring a new concept in assessment.

Currents in pharmacy teaching & learning

Wolcott MD, Lobczowski NG, Zeeman JM, McLaughlin JE.
PMID: 34799058
Curr Pharm Teach Learn. 2021 Nov;13(11):1451-1456. doi: 10.1016/j.cptl.2021.09.003. Epub 2021 Sep 23.

INTRODUCTION: The ability to identify criteria (ATIC) refers to an examinee's capacity to distinguish the construct being evaluated. Previous research indicates ATIC can be predictive of performance on some assessments. This exploratory study investigated the relationship between a participant's...

VisBOL2-Improving Web-Based Visualization for Synthetic Biology Designs.

ACS synthetic biology

Hatch B, Meng L, Mante J, McLaughlin JA, Scott-Brown J, Myers CJ.
PMID: 34324811
ACS Synth Biol. 2021 Aug 20;10(8):2111-2115. doi: 10.1021/acssynbio.1c00147. Epub 2021 Jul 29.

VisBOL is a web-based visualization tool used to depict genetic circuit designs. This tool depicts simple DNA circuits adequately, but it has become increasingly outdated as new versions of SBOL Visual were released. This paper introduces VisBOL2, a heavily...

Prevalence and predictors of peripheral neuropathy after breast cancer treatment.

Cancer medicine

Kamgar M, Greenwald MK, Assad H, Hastert TA, McLaughlin EM, Reding KW, Paskett ED, Bea JW, Shadyab AH, Neuhouser ML, Nassir R, Crane TE, Sreeram K, Simon MS.
PMID: 34390205
Cancer Med. 2021 Oct;10(19):6666-6676. doi: 10.1002/cam4.4202. Epub 2021 Aug 14.

BACKGROUND: Many of the 3.8 million breast cancer survivors in the United States experience long-term side effects of cancer therapy including peripheral neuropathy (PN). We assessed the prevalence and predictors of PN among women with breast cancer followed in...

Development of an organomineral fertiliser formulation that improves tomato growth and sustains arbuscular mycorrhizal colonisation.

The Science of the total environment

Ngo HTT, Watts-Williams SJ, Panagaris A, Baird R, McLaughlin MJ, Cavagnaro TR.
PMID: 34838906
Sci Total Environ. 2021 Nov 26;151977. doi: 10.1016/j.scitotenv.2021.151977. Epub 2021 Nov 26.

Achieving sustainable agricultural development requires the efficient use of nutrient resources for crop production. Recovering nutrients from animal manures may play a key role in achieving this. Animal manures typically have low nutrient concentrations, and in ratios that are...

A Multi-Omic Huntington's Disease Transgenic Sheep-Model Database for Investigating Disease Pathogenesis.

Journal of Huntington's disease

Mears ER, Handley RR, Grant MJ, Reid SJ, Day BT, Rudiger SR, McLaughlan CJ, Verma PJ, Bawden SC, Patassini S, Unwin RD, Cooper GJS, Gusella JF, MacDonald ME, Brauning R, Maclean P, Pearson JF, Waldvogel HJ, Faull RLM, Snell RG.
PMID: 34420978
J Huntingtons Dis. 2021;10(4):423-434. doi: 10.3233/JHD-210482.

BACKGROUND: The pathological mechanism of cellular dysfunction and death in Huntington's disease (HD) is not well defined. Our transgenic HD sheep model (OVT73) was generated to investigate these mechanisms and for therapeutic testing. One particular cohort of animals has...

Childhood head trauma and the risk of childhood brain tumours: A case-control study in Ontario, Canada.

International journal of cancer

Cheng S, McLaughlin JR, Brown MC, Al-Sawaihey H, Rutka J, Bouffet E, Hawkins C, Cairney AE, Ranger A, Fleming AJ, Johnston D, Greenberg M, Malkin D, Hung RJ.
PMID: 34520575
Int J Cancer. 2021 Sep 14; doi: 10.1002/ijc.33805. Epub 2021 Sep 14.

Head trauma in early childhood has been hypothesized as a potential risk factor for childhood brain tumours (CBTs). However, head trauma has not been extensively studied in the context of CBTs and existing studies have yielded conflicting results. A...

Characterisation of 99mTc EDDA/HYNIC-TOC (Tektrotyd) physiological and neuroendocrine tumour uptake using SPECT/CT standardised uptake values: initial experience.

Nuclear medicine communications

Reilly C, Gemmell AJ, McLaughlin IM, Fleming R, Reed N, McIntosh D, Nicol A.
PMID: 33741866
Nucl Med Commun. 2021 Aug 01;42(8):935-939. doi: 10.1097/MNM.0000000000001416.

99mTc Ethylene diamine N,N'-diacetic acid hydrazinonicotinamide-conjugated Tyr3-octreotide (99mTc EDDA/HYNIC-TOC) single photon emission tomography/computed tomography (SPECT/CT) imaging of somatostatin receptors is used in the assessment of neuroendocrine tumours (NETs). The objective of this study was to characterise quantitative standardised uptake...

Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects.

Proceedings of the National Academy of Sciences of the United States of America

Kandasamy R, Hillhouse TM, Livingston KE, Kochan KE, Meurice C, Eans SO, Li MH, White AD, Roques BP, McLaughlin JP, Ingram SL, Burford NT, Alt A, Traynor JR.
PMID: 33846240
Proc Natl Acad Sci U S A. 2021 Apr 20;118(16). doi: 10.1073/pnas.2000017118.

Positive allosteric modulators (PAMs) of the mu-opioid receptor (MOR) have been hypothesized as potentially safer analgesics than traditional opioid drugs. This is based on the idea that PAMs will promote the action of endogenous opioid peptides while preserving their...

Showing 289 to 300 of 300 entries