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Showing 13 to 14 of 14 entries
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Modulating BAP1 expression affects ROS homeostasis, cell motility and mitochondrial function.

Oncotarget

Hebert L, Bellanger D, Guillas C, Campagne A, Dingli F, Loew D, Fievet A, Jacquemin V, Popova T, Jean D, Mechta-Grigoriou F, Margueron R, Stern MH.
PMID: 29069806
Oncotarget. 2017 Aug 03;8(42):72513-72527. doi: 10.18632/oncotarget.19872. eCollection 2017 Sep 22.

The tumor suppressor BAP1 associates with ASXL1/2 to form the core Polycomb complex PR-DUB, which catalyzes the removal of mono-ubiquitin from several substrates including histone H2A. This complex also mediates the poly-deubiquitination of HCFC1, OGT and PCG1-α, preventing them...

Tumor Cells and Cancer-Associated Fibroblasts: An Updated Metabolic Perspective.

Cancers

Gentric G, Mechta-Grigoriou F.
PMID: 33499022
Cancers (Basel). 2021 Jan 22;13(3). doi: 10.3390/cancers13030399.

During the past decades, metabolism and redox imbalance have gained considerable attention in the cancer field. In addition to the well-known Warburg effect occurring in tumor cells, numerous other metabolic deregulations have now been reported. Indeed, metabolic reprograming in...

Showing 13 to 14 of 14 entries