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Entinostat plus Pembrolizumab in Patients with Metastatic NSCLC Previously Treated with Anti-PD-(L)1 Therapy.

Clinical cancer research : an official journal of the American Association for Cancer Research

Hellmann MD, Jänne PA, Opyrchal M, Hafez N, Raez LE, Gabrilovich DI, Wang F, Trepel JB, Lee MJ, Yuno A, Lee S, Brouwer S, Sankoh S, Wang L, Tamang D, Schmidt EV, Meyers ML, Ramalingam SS, Shum E, Ordentlich P.
PMID: 33203644
Clin Cancer Res. 2021 Feb 15;27(4):1019-1028. doi: 10.1158/1078-0432.CCR-20-3305. Epub 2020 Nov 17.

PURPOSE: New therapies are needed to treat immune checkpoint inhibitor-resistant non-small cell lung cancer (NSCLC) and identify biomarkers to personalize treatment. Epigenetic therapies, including histone deacetylase inhibitors, may synergize with programmed cell death-1 (PD-1) blockade to overcome resistance. We...

Cite
Hellmann MD, Jänne PA, Opyrchal M, et al. Entinostat plus Pembrolizumab in Patients with Metastatic NSCLC Previously Treated with Anti-PD-(L)1 Therapy. Clin Cancer Res. 2020;27(4):1019-1028doi: 10.1158/1078-0432.CCR-20-3305.
Hellmann, M. D., Jänne, P. A., Opyrchal, M., Hafez, N., Raez, L. E., Gabrilovich, D. I., Wang, F., Trepel, J. B., Lee, M. J., Yuno, A., Lee, S., Brouwer, S., Sankoh, S., Wang, L., Tamang, D., Schmidt, E. V., Meyers, M. L., Ramalingam, S. S., Shum, E., & Ordentlich, P. (2021). Entinostat plus Pembrolizumab in Patients with Metastatic NSCLC Previously Treated with Anti-PD-(L)1 Therapy. Clinical cancer research : an official journal of the American Association for Cancer Research, 27(4), 1019-1028. https://doi.org/10.1158/1078-0432.CCR-20-3305
Hellmann, Matthew D, et al. "Entinostat plus Pembrolizumab in Patients with Metastatic NSCLC Previously Treated with Anti-PD-(L)1 Therapy." Clinical cancer research : an official journal of the American Association for Cancer Research vol. 27,4 (2021): 1019-1028. doi: https://doi.org/10.1158/1078-0432.CCR-20-3305
Hellmann MD, Jänne PA, Opyrchal M, Hafez N, Raez LE, Gabrilovich DI, Wang F, Trepel JB, Lee MJ, Yuno A, Lee S, Brouwer S, Sankoh S, Wang L, Tamang D, Schmidt EV, Meyers ML, Ramalingam SS, Shum E, Ordentlich P. Entinostat plus Pembrolizumab in Patients with Metastatic NSCLC Previously Treated with Anti-PD-(L)1 Therapy. Clin Cancer Res. 2021 Feb 15;27(4):1019-1028. doi: 10.1158/1078-0432.CCR-20-3305. Epub 2020 Nov 17. PMID: 33203644; PMCID: PMC7887114.
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Synthetic Derivatives of Ciclopirox are Effective Inhibitors of .

ACS omega

Lin J, Zangi M, Kumar TVNH, Shakar Reddy M, Reddy LVR, Sadhukhan SK, Bradley DP, Moreira-Walsh B, Edwards TC, O'Dea AT, Tavis JE, Meyers MJ, Donlin MJ.
PMID: 33817509
ACS Omega. 2021 Mar 15;6(12):8477-8487. doi: 10.1021/acsomega.1c00273. eCollection 2021 Mar 30.

Opportunistic fungal infections caused by

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Lin J, Zangi M, Kumar TVNH, et al. Synthetic Derivatives of Ciclopirox are Effective Inhibitors of . ACS Omega. 2021;6(12):8477-8487doi: 10.1021/acsomega.1c00273.
Lin, J., Zangi, M., Kumar, T. V. N. H., Shakar Reddy, M., Reddy, L. V. R., Sadhukhan, S. K., Bradley, D. P., Moreira-Walsh, B., Edwards, T. C., O'Dea, A. T., Tavis, J. E., Meyers, M. J., & Donlin, M. J. (2021). Synthetic Derivatives of Ciclopirox are Effective Inhibitors of . ACS omega, 6(12), 8477-8487. https://doi.org/10.1021/acsomega.1c00273
Lin, Jeffrey, et al. "Synthetic Derivatives of Ciclopirox are Effective Inhibitors of ." ACS omega vol. 6,12 (2021): 8477-8487. doi: https://doi.org/10.1021/acsomega.1c00273
Lin J, Zangi M, Kumar TVNH, Shakar Reddy M, Reddy LVR, Sadhukhan SK, Bradley DP, Moreira-Walsh B, Edwards TC, O'Dea AT, Tavis JE, Meyers MJ, Donlin MJ. Synthetic Derivatives of Ciclopirox are Effective Inhibitors of . ACS Omega. 2021 Mar 15;6(12):8477-8487. doi: 10.1021/acsomega.1c00273. eCollection 2021 Mar 30. PMID: 33817509; PMCID: PMC8015083.
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