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Optimizing Spray-Dried Porous Particles for High Dose Delivery with a Portable Dry Powder Inhaler.

Pharmaceutics

Son YJ, Miller DP, Weers JG.
PMID: 34575603
Pharmaceutics. 2021 Sep 21;13(9). doi: 10.3390/pharmaceutics13091528.

This manuscript critically reviews the design and delivery of spray-dried particles for the achievement of high total lung doses (TLD) with a portable dry powder inhaler. We introduce a new metric termed the product density, which is simply the...

Efficacy and safety of fevipiprant in patients with uncontrolled asthma: Two replicate, phase 3, randomised, double-blind, placebo-controlled trials (ZEAL-1 and ZEAL-2).

EClinicalMedicine

Castro M, Kerwin E, Miller D, Pedinoff A, Sher L, Cardenas P, Knorr B, Lawrence D, Ossa D, Wang W, Maspero JF.
PMID: 33997741
EClinicalMedicine. 2021 Apr 25;35:100847. doi: 10.1016/j.eclinm.2021.100847. eCollection 2021 May.

BACKGROUND: These studies assessed the efficacy and safety of fevipiprant, an oral antagonist of the prostaglandin DMETHODS: ZEAL-1 (NCT03215758) and ZEAL-2 (NCT03226392) are two replicate, phase 3, multicentre, randomised, double-blind, placebo-controlled, parallel-group studies in which fevipiprant 150 mg once...

Cyclicality, Mortality, and the Value of Time: The Case of Coffee Price Fluctuations and Child Survival in Colombia.

The journal of political economy

Miller G, Urdinola BP.
PMID: 22090662
J Polit Econ. 2010 Feb;118(1):113-155. doi: 10.1086/651673.

Recent studies demonstrate procyclical mortality in wealthy countries, but there are reasons to expect a countercyclical relationship in developing nations. We investigate how child survival in Colombia responds to fluctuations in world Arabica coffee prices - and document starkly...

Black Resilience: A Strategic Asset for Engaging Heterosexual Black Canadian Men in Community Responses to HIV.

Journal of racial and ethnic health disparities

Antabe R, Miller D, Kohoun B, Okonufua O, Husbands W.
PMID: 33686622
J Racial Ethn Health Disparities. 2021 Mar 08; doi: 10.1007/s40615-021-01011-w. Epub 2021 Mar 08.

Black people's disproportionate burden of HIV in Canada has raised questions about whether they are sufficiently resilient to HIV, and how to promote resilience. In this paper, we critically examine the issue of resilience among heterosexual Black men in...

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Challenge Experiments in Nonhuman Primates: An Ethical Perspective.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

DeGrazia D, Miller FG.
PMID: 33786589
Clin Infect Dis. 2021 Dec 06;73(11):2121-2125. doi: 10.1093/cid/ciab278.

The coronavirus disease 2019 (COVID-19) pandemic has stimulated massive investment in biomedical research with the aims of understanding the disease and developing effective vaccine and therapeutic interventions. What role should animal research play in this scientific endeavor? Both the...

Targeting treatment options for castration-resistant prostate cancer.

American journal of clinical and experimental urology

Miller DR, Ingersoll MA, Teply BA, Lin MF.
PMID: 33816699
Am J Clin Exp Urol. 2021 Feb 15;9(1):101-120. eCollection 2021.

Prostate cancer (PCa) is the most commonly diagnosed solid tumor and the second leading cause of cancer-related deaths in U.S. men in 2020. Androgen-deprivation therapy (ADT) is the standard of care for metastatic PCa. Unfortunately, PCa relapse often occurs...

A first-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and safety in skin cancer patients.

Contemporary clinical trials communications

Yamada M, Miller DM, Lowe M, Rowe C, Wood D, Soyer HP, Byrnes-Blake K, Parrish-Novak J, Ishak L, Olson JM, Brandt G, Griffin P, Spelman L, Prow TW.
PMID: 34401600
Contemp Clin Trials Commun. 2021 Aug 04;23:100830. doi: 10.1016/j.conctc.2021.100830. eCollection 2021 Sep.

BLZ-100 (tozuleristide) is an intraoperative fluorescent imaging agent that selectively detects malignant tissue and can be used in real time to guide tumor resection. The purpose of this study was to assess the safety, tolerability, and pharmacokinetics of BLZ-100...

The bachelor's to Ph.D. STEM pipeline no longer leaks more women than men: a 30-year analysis.

Miller DI, Wai J.
UIID-AD: 719
2015;6. doi: 10.3389/fpsyg.2015.00037.

For decades, research and public discourse about gender and science have often assumed that women are more likely than men to "leak" from the science pipeline at multiple points after entering college. We used retrospective longitudinal methods to investigate...

Exploring and Enhancing Spatial Thinking: Links to Achievement in Science, Technology, Engineering, and Mathematics?.

Uttal DH, Miller DI, Newcombe NS.
UIID-AD: 310
2013;22:367-373. doi: 10.1177/0963721413484756.

Although neglected in traditional education, spatial thinking plays a critical role in achievement in science, technology, engineering, and mathematics (STEM) fields. We review this relationship and investigate the malleability of spatial thinking. Can spatial thinking be improved with training,...

Showing 2797 to 2805 of 2805 entries