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Showing 13 to 20 of 20 entries
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Is early migration enough to explain late clinical loosening of hip prostheses?.

EFORT open reviews

Mjöberg B.
PMID: 32175098
EFORT Open Rev. 2020 Feb 26;5(2):113-117. doi: 10.1302/2058-5241.5.190014. eCollection 2020 Feb.

Prosthetic loosening has been debated for decades, both in terms of the timing and nature of the triggering events. Multiple radiostereometric studies of hip prostheses have now shown that early migration poses a risk of future clinical failure, but...

Functional Differences between Human NKp44(-) and NKp44(+) RORC(+) Innate Lymphoid Cells.

Frontiers in immunology

Hoorweg K, Peters CP, Cornelissen F, Aparicio-Domingo P, Papazian N, Kazemier G, Mjösberg JM, Spits H, Cupedo T.
PMID: 22566953
Front Immunol. 2012 Apr 09;3:72. doi: 10.3389/fimmu.2012.00072. eCollection 2012.

Human RORC(+) lymphoid tissue inducer cells are part of a rapidly expanding family of innate lymphoid cells (ILC) that participate in innate and adaptive immune responses as well as in lymphoid tissue (re) modeling. The assessment of a potential...

COVID-19-specific metabolic imprint yields insights into multiorgan system perturbations.

European journal of immunology

Cornillet M, Strunz B, Rooyackers O, Ponzetta A, Chen P, Muvva JR, Akber M, Buggert M, Chambers BJ, Dzidic M, Filipovic I, Gorin JB, Gredmark-Russ S, Hertwig L, Klingström J, Kokkinou E, Kvedaraite E, Lourda M, Mjösberg J, Maucourant C, Norrby-Teglund A, Parrot T, Perez-Potti A, Rivera-Ballesteros O, Sandberg JK, Sandberg JT, Sekine T, Svensson M, Varnaite R, Eriksson LI, Aleman S, Strålin K, Ljunggren HG, Björkström NK.
PMID: 34837225
Eur J Immunol. 2021 Nov 26; doi: 10.1002/eji.202149626. Epub 2021 Nov 26.

Corona disease 2019 (COVID-19) affects multiple organ systems. Recent studies have indicated perturbations in the circulating metabolome linked to COVID-19 severity. However, several questions pertain with respect to the metabolome in COVID-19. We performed an in-depth assessment of 1129...

Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing.

Cell research

Mazzurana L, Czarnewski P, Jonsson V, Wigge L, Ringnér M, Williams TC, Ravindran A, Björklund ÅK, Säfholm J, Nilsson G, Dahlén SE, Orre AC, Al-Ameri M, Höög C, Hedin C, Szczegielniak S, Almer S, Mjösberg J.
PMID: 33420427
Cell Res. 2021 May;31(5):554-568. doi: 10.1038/s41422-020-00445-x. Epub 2021 Jan 08.

The impact of the microenvironment on innate lymphoid cell (ILC)-mediated immunity in humans remains largely unknown. Here we used full-length Smart-seq2 single-cell RNA-sequencing to unravel tissue-specific transcriptional profiles and heterogeneity of CD127

Hysterectomy Provides Benefit in Health-Related Quality of Life: A 10-Year Follow-up Study.

Journal of minimally invasive gynecology

Rahkola-Soisalo P, Brummer T, Jalkanen J, Sjöberg J, Sintonen H, Roine RP, Härkki P.
PMID: 31404711
J Minim Invasive Gynecol. 2020 May - Jun;27(4):868-874. doi: 10.1016/j.jmig.2019.08.009. Epub 2019 Aug 09.

STUDY OBJECTIVE: This study aims to evaluate short- and long-term effects of hysterectomy on health-related quality of life (HRQoL) and compare that with a representative age-standardized sample from the general population.DESIGN: A prospective survey as a part of FINHYST...

COVID-19 specific metabolic imprint yields insights into multi organ-system perturbations.

European journal of immunology

Cornillet M, Strunz B, Rooyackers O, Ponzetta A, Chen P, Muvva JR, Akber M, Buggert M, Chambers BJ, Dzidic M, Filipovic I, Gorin JB, Gredmark-Russ S, Hertwig L, Klingström J, Kokkinou E, Kvedaraite E, Lourda M, Mjösberg J, Maucourant C, Norrby-Teglund A, Parrot T, Perez-Potti A, Rivera-Ballesteros O, Sandberg JK, Sandberg JT, Sekine T, Svensson M, Varnaite R, Eriksson LI, Aleman S, Strålin K, Ljunggren HG, Björkström NK.
PMID: 34837225
Eur J Immunol. 2021 Nov 26; doi: 10.1002/eji.202149626. Epub 2021 Nov 26.

COVID-19 affects multiple organ-systems. Recent studies have indicated perturbations in the circulating metabolome linked to COVID-19 severity. However, several questions pertain with respect to the metabolome in COVID-19. We performed an in-depth assessment of 1129 unique metabolites in 27...

Crohn's Disease Is Associated With Activation of Circulating Innate Lymphoid Cells.

Inflammatory bowel diseases

Mazzurana L, Bonfiglio F, Forkel M, D'Amato M, Halfvarson J, Mjösberg J.
PMID: 33295628
Inflamm Bowel Dis. 2021 Jun 15;27(7):1128-1138. doi: 10.1093/ibd/izaa316.

BACKGROUND: Inflammatory bowel disease (IBD) is associated with disturbed mucosal innate lymphoid cell (ILC) composition, which is correlated to the degree of intestinal inflammation. However, it remains unclear whether circulating ILCs are dysregulated in patients with IBD.METHODS: Blood samples...

Hodgkin Lymphoma Monozygotic Triplets Reveal Divergences in DNA Methylation Signatures.

Frontiers in oncology

Xia C, Olsen TK, Zirakzadeh AA, Almamoun R, Sjöholm LK, Dahlström J, Sjöberg J, Claesson HE, Johnsen JI, Winqvist O, Xu D, Ekström TJ, Björkholm M, Strååt K.
PMID: 33363029
Front Oncol. 2020 Dec 09;10:598872. doi: 10.3389/fonc.2020.598872. eCollection 2020.

We studied DNA methylation profiles in four different cell populations from a unique constellation of monozygotic triplets in whom two had developed Hodgkin Lymphoma (HL). We detected shared differences in DNA methylation signatures when comparing the two HL-affected triplets...

Showing 13 to 20 of 20 entries