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Showing 313 to 320 of 320 entries
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Delayed debridement of open tibia fractures beyond 24 and 48 h does not appear to increase infection and reoperation risk.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

Heckmann ND, Davis JA, Mombell K, Bradley A, Chung BC, Husak L, Marecek G.
PMID: 34195854
Eur J Orthop Surg Traumatol. 2021 Jun 30; doi: 10.1007/s00590-021-03057-2. Epub 2021 Jun 30.

PURPOSE: Surgical debridement is critical to the treatment of open tibia fractures, although the effects of delayed debridement have not been well-established. Other factors such as Gustilo-Anderson type, prompt initiation of antibiotics, and time to definitive closure may be...

Colorectal cancer with microsatellite instability: Right-sided location and signet ring cell histology are associated with nodal metastases, and extranodal extension influences disease-free survival.

Pathology, research and practice

Piredda ML, Ammendola S, Sciammarella C, Turri G, Bagante F, Fassan M, Mafficini A, Mombello A, Cataldi S, Paolino G, Mattiolo P, Florena AM, Genna M, Fior F, Cheng L, Lawlor RT, Scarpa A, Pedrazzani C, Luchini C.
PMID: 34119815
Pathol Res Pract. 2021 Aug;224:153519. doi: 10.1016/j.prp.2021.153519. Epub 2021 Jun 08.

Colorectal cancer (CRC) with microsatellite instability (MSI) accounts for 15-18 % of all CRCs and represents the category with the best prognosis. This study aimed at determining any possible clinical/pathological features associated with a higher risk of nodal metastasization...

A dual compartment cuvette system for correcting scattering in whole-cell absorbance spectroscopy of photosynthetic microorganisms.

Photosynthesis research

Hervey JRD, Bombelli P, Lea-Smith DJ, Hulme AK, Hulme NR, Rullay AK, Keighley R, Howe CJ.
PMID: 34390453
Photosynth Res. 2021 Aug 14; doi: 10.1007/s11120-021-00866-8. Epub 2021 Aug 14.

Absorption spectroscopy is widely used to determine absorption and transmission spectra of chromophores in solution, in addition to suspensions of particles, including micro-organisms. Light scattering, caused by photons deflected from part or all of the cells or other particles...

Advances in Lung Cancer Imaging and Therapy.

Cancers

Lopci E, Morbelli S.
PMID: 35008219
Cancers (Basel). 2021 Dec 23;14(1). doi: 10.3390/cancers14010058.

This series of eight papers (five original articles, two reviews and one meta-analysis) is presented by international leaders covering various aspects of lung cancer management, starting with diagnostic imaging and analyzing the novel perspectives of therapy [...].

Bio-Inspired Systems in Nonsurgical Periodontal Therapy to Reduce Contaminated Aerosol during COVID-19: A Comprehensive and Bibliometric Review.

Journal of clinical medicine

Butera A, Maiorani C, Natoli V, Bruni A, Coscione C, Magliano G, Giacobbo G, Morelli A, Moressa S, Scribante A.
PMID: 33276626
J Clin Med. 2020 Dec 02;9(12). doi: 10.3390/jcm9123914.

BACKGROUND: On 30 January 2020, a public health emergency of international concern was declared as a result of the new COVID-19 disease, caused by the SARS-CoV-2 virus. This virus is transmitted by air and, therefore, clinical practices with the...

Alpha-synuclein seeds in olfactory mucosa and cerebrospinal fluid of patients with dementia with Lewy bodies.

Brain communications

Perra D, Bongianni M, Novi G, Janes F, Bessi V, Capaldi S, Sacchetto L, Tagliapietra M, Schenone G, Morbelli S, Fiorini M, Cattaruzza T, Mazzon G, Orrù CD, Catalan M, Polverino P, Bernardini A, Pellitteri G, Valente M, Bertolotti C, Nacmias B, Maggiore G, Cavallaro T, Manganotti P, Gigli G, Monaco S, Nobili F, Zanusso G.
PMID: 33870192
Brain Commun. 2021 Mar 22;3(2):fcab045. doi: 10.1093/braincomms/fcab045. eCollection 2021.

In patients with suspected dementia with Lewy bodies, the detection of the disease-associated α-synuclein in easily accessible tissues amenable to be collected using minimally invasive procedures remains a major diagnostic challenge. This approach has the potential to take advantage...

Consolidation and Maintenance in Newly Diagnosed Multiple Myeloma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Sonneveld P, Dimopoulos MA, Beksac M, van der Holt B, Aquino S, Ludwig H, Zweegman S, Zander T, Zamagni E, Wester R, Hajek R, Pantani L, Dozza L, Gay F, Cafro A, De Rosa L, Morelli A, Gregersen H, Gulbrandsen N, Cornelisse P, Troia R, Oliva S, van de Velden V, Wu K, Ypma PF, Bos G, Levin MD, Pour L, Driessen C, Broijl A, Croockewit A, Minnema MC, Waage A, Hveding C, van de Donk NWCJ, Offidani M, Palumbo GA, Spencer A, Boccadoro M, Cavo M.
PMID: 34520219
J Clin Oncol. 2021 Nov 10;39(32):3613-3622. doi: 10.1200/JCO.21.01045. Epub 2021 Sep 14.

PURPOSE: To address the role of consolidation treatment for newly diagnosed, transplant eligible patients with multiple myeloma in a controlled clinical trial.PATIENTS AND METHODS: The EMN02/HOVON95 trial compared consolidation treatment with two cycles of bortezomib, lenalidomide, and dexamethasone (VRD)...

Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action.

Toxicology in vitro : an international journal published in association with BIBRA

Escher SE, Aguayo-Orozco A, Benfenati E, Bitsch A, Braunbeck T, Brotzmann K, Bois F, van der Burg B, Castel J, Exner T, Gadaleta D, Gardner I, Goldmann D, Hatley O, Golbamaki N, Graepel R, Jennings P, Limonciel A, Long A, Maclennan R, Mombelli E, Norinder U, Jain S, Capinha LS, Taboureau OT, Tolosa L, Vrijenhoek NG, van Vugt-Lussenburg BMA, Walker P, van de Water B, Wehr M, White A, Zdrazil B, Fisher C.
PMID: 34757180
Toxicol In Vitro. 2022 Mar;79:105269. doi: 10.1016/j.tiv.2021.105269. Epub 2021 Oct 29.

Read-across approaches often remain inconclusive as they do not provide sufficient evidence on a common mode of action across the category members. This read-across case study on thirteen, structurally similar, branched aliphatic carboxylic acids investigates the concept of using...

Showing 313 to 320 of 320 entries