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Showing 145 to 153 of 153 entries
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Nanoparticle delivery of miR-122 inhibits colorectal cancer liver metastasis.

Cancer research

Sendi H, Yazdimamaghani M, Hu M, Sultanpuram N, Wang J, Moody AS, McCabe E, Zhang J, Graboski A, Li L, Rojas JD, Dayton PA, Huang L, Wang AZ.
PMID: 34753773
Cancer Res. 2021 Nov 09; doi: 10.1158/0008-5472.CAN-21-2269. Epub 2021 Nov 09.

Liver metastasis is a leading cause of cancer morbidity and mortality. Thus, there has been strong interest in the development of therapeutics that can effectively prevent liver metastasis. One potential strategy is to utilize molecules that have broad effects...

Screening for occult coronary artery disease in potential kidney transplant recipients: time for reappraisal?.

Clinical kidney journal

Ferro CJ, Berry M, Moody WE, George S, Sharif A, Townend JN.
PMID: 34950460
Clin Kidney J. 2021 Jul 06;14(12):2472-2482. doi: 10.1093/ckj/sfab103. eCollection 2021 Dec.

Screening for occult coronary artery disease in potential kidney transplant recipients has become entrenched in current medical practice as the standard of care and is supported by national and international clinical guidelines. However, there is increasing and robust evidence...

Nanoparticle Delivery of miR-122 Inhibits Colorectal Cancer Liver Metastasis.

Cancer research

Sendi H, Yazdimamaghani M, Hu M, Sultanpuram N, Wang J, Moody AS, McCabe E, Zhang J, Graboski A, Li L, Rojas JD, Dayton PA, Huang L, Wang AZ.
PMID: 34753773
Cancer Res. 2022 Jan 01;82(1):105-113. doi: 10.1158/0008-5472.CAN-21-2269. Epub 2021 Nov 09.

Liver metastasis is a leading cause of cancer morbidity and mortality. Thus, there has been strong interest in the development of therapeutics that can effectively prevent liver metastasis. One potential strategy is to utilize molecules that have broad effects...

Prognostic value of coronary risk factors, exercise capacity and single photon emission computed tomography in liver transplantation candidates: A 5-year follow-up study.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Moody WE, Holloway B, Arumugam P, Gill S, Wahid YS, Boivin CM, Thomson LE, Berman DS, Armstrong MJ, Ferguson J, Steeds RP.
PMID: 32394403
J Nucl Cardiol. 2021 Dec;28(6):2876-2891. doi: 10.1007/s12350-020-02126-z. Epub 2020 May 11.

BACKGROUND: Although consensus-based guidelines support noninvasive stress testing prior to orthotopic liver transplantation (OLT), the optimal screening strategy for assessment of coronary artery disease in patients with end-stage liver disease (ESLD) is unclear. This study sought to determine the...

Prognostic value of coronary risk factors, exercise capacity and single photon emission computed tomography in liver transplantation candidates: A 5-year follow-up study.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Moody WE, Holloway B, Arumugam P, Gill S, Wahid YS, Boivin CM, Thomson LE, Berman DS, Armstrong MJ, Ferguson J, Steeds RP.
PMID: 32394403
J Nucl Cardiol. 2021 Dec;28(6):2876-2891. doi: 10.1007/s12350-020-02126-z. Epub 2020 May 11.

BACKGROUND: Although consensus-based guidelines support noninvasive stress testing prior to orthotopic liver transplantation (OLT), the optimal screening strategy for assessment of coronary artery disease in patients with end-stage liver disease (ESLD) is unclear. This study sought to determine the...

Cardiac magnetic resonance imaging: insights into developmental programming and its consequences for aging.

Journal of developmental origins of health and disease

Clarke GD, Li J, Kuo AH, Moody AJ, Nathanielsz PW.
PMID: 33349289
J Dev Orig Health Dis. 2021 Apr;12(2):203-219. doi: 10.1017/S2040174420001233. Epub 2020 Dec 22.

Cardiovascular diseases (CVD) are important consequences of adverse perinatal conditions such as fetal hypoxia and maternal malnutrition. Cardiac magnetic resonance imaging (CMR) can produce a wealth of physiological information related to the development of the heart. This review outlines...

Imaging methods to evaluate tumor microenvironment factors affecting nanoparticle drug delivery and antitumor response.

Cancer drug resistance (Alhambra, Calif.)

Moody AS, Dayton PA, Zamboni WC.
PMID: 34796317
Cancer Drug Resist. 2021;4:382-413. doi: 10.20517/cdr.2020.94. Epub 2021 Jun 19.

Standard small molecule and nanoparticulate chemotherapies are used for cancer treatment; however, their effectiveness remains highly variable. One reason for this variable response is hypothesized to be due to nonspecific drug distribution and heterogeneity of the tumor microenvironment, which...

Cellular dormancy in minimal residual disease following targeted therapy.

Breast cancer research : BCR

Ruth JR, Pant DK, Pan TC, Seidel HE, Baksh SC, Keister BA, Singh R, Sterner CJ, Bakewell SJ, Moody SE, Belka GK, Chodosh LA.
PMID: 34088357
Breast Cancer Res. 2021 Jun 04;23(1):63. doi: 10.1186/s13058-021-01416-9.

BACKGROUND: Breast cancer mortality is principally due to tumor recurrence, which can occur following extended periods of clinical remission that may last decades. While clinical latency has been postulated to reflect the ability of residual tumor cells to persist...

RUNX1 Regulates a Transcription Program That Affects the Dynamics of Cell Cycle Entry of Naive Resting B Cells.

Journal of immunology (Baltimore, Md. : 1950)

Thomsen I, Kunowska N, de Souza R, Moody AM, Crawford G, Wang YF, Khadayate S, Whilding C, Strid J, Karimi MM, Barr AR, Dillon N, Sabbattini P.
PMID: 34810221
J Immunol. 2021 Nov 22; doi: 10.4049/jimmunol.2001367. Epub 2021 Nov 22.

RUNX1 is a transcription factor that plays key roles in hematopoietic development and in hematopoiesis and lymphopoiesis. In this article, we report that RUNX1 regulates a gene expression program in naive mouse B cells that affects the dynamics of...

Showing 145 to 153 of 153 entries