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Showing 25 to 36 of 68 entries
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A narrative review of central nervous system involvement in acute leukemias.

Annals of translational medicine

Deak D, Gorcea-Andronic N, Sas V, Teodorescu P, Constantinescu C, Iluta S, Pasca S, Hotea I, Turcas C, Moisoiu V, Zimta AA, Galdean S, Steinheber J, Rus I, Rauch S, Richlitzki C, Munteanu R, Jurj A, Petrushev B, Selicean C, Marian M, Soritau O, Andries A, Roman A, Dima D, Tanase A, Sigurjonsson O, Tomuleasa C.
PMID: 33553361
Ann Transl Med. 2021 Jan;9(1):68. doi: 10.21037/atm-20-3140.

Acute leukemias (both myeloid and lymphoblastic) are a group of diseases for which each year more successful therapies are implemented. However, in a subset of cases the overall survival (OS) is still exceptionally low due to the infiltration of...

SERS-Based Evaluation of the DNA Methylation Pattern Associated With Progression in Clonal Leukemogenesis of Down Syndrome.

Frontiers in bioengineering and biotechnology

Moisoiu V, Sas V, Stefancu A, Iancu SD, Jurj A, Pasca S, Iluta S, Zimta AA, Tigu AB, Teodorescu P, Turcas C, Blag C, Dima D, Popa G, Arghirescu S, Man S, Colita A, Leopold N, Tomuleasa C.
PMID: 34368097
Front Bioeng Biotechnol. 2021 Jul 23;9:703268. doi: 10.3389/fbioe.2021.703268. eCollection 2021.

Here we show that surface-enhanced Raman scattering (SERS) analysis captures the relative hypomethylation of DNA from patients with acute leukemia associated with Down syndrome (AL-DS) compared with patients diagnosed with transient leukemia associated with Down syndrome (TL-DS), an information...

Assessment of Transportation by Air for Patients with Acute ST-Elevation Myocardial Infarction from Non-PCI Centers.

Healthcare (Basel, Switzerland)

Trifan AL, Dragomir L, Anghele M, Elkan EM, Munteanu S, Moscu C, Stoian VI, Telehuz A, Zlati ML, Lungu M, Voinescu DC, Cimpoesu DC, Stoleriu G, Sandu I, Sapira V.
PMID: 33800429
Healthcare (Basel). 2021 Mar 08;9(3). doi: 10.3390/healthcare9030299.

The aim of this study was to assess the delays that can potentially occur in the emergency transfer of patients with ST-elevation myocardial infarction (STEMI) to percutaneous coronary intervention (PCI) centers. We conducted a retrospective study using the medical...

Pulmonary Embolism in COVID-19 Patients: Which Diagnostic Algorithm Should We Use?.

Frontiers in cardiovascular medicine

Porfidia A, Mosoni C, Talerico R, Porceddu E, Lupascu A, Tondi P, Landi F, Pola R.
PMID: 34485411
Front Cardiovasc Med. 2021 Aug 13;8:714003. doi: 10.3389/fcvm.2021.714003. eCollection 2021.

No abstract available.

First Reported Case in Romania of a Successfully Treated Severe COVID-19 in a Kidney Transplant Recipient: A Focus on Acute Kidney Injury.

Case reports in nephrology and dialysis

Tosa F, Manaila R, Elec A, Moisoiu T, Ghervan L, Elec F.
PMID: 33442550
Case Rep Nephrol Dial. 2020 Dec 07;10(3):174-179. doi: 10.1159/000512606. eCollection 2020.

As coronavirus disease 2019 (COVID-19) caused by the novel virus SARS-CoV-2 is expanding worldwide, kidney involvement seems to be part of the spectrum of its effects. Moreover, the prognosis of the disease seems to be worse in immunocompromised patients...

Visceral adipose tissue glucose uptake is linked to prognosis in multiple myeloma patients: An exploratory study.

Clinical nutrition (Edinburgh, Scotland)

da Cunha Júnior AD, Silveira MN, Takahashi MES, de Souza EM, Mosci C, Ramos CD, Brambilla SR, Pericole FV, Prado CM, Mendes MCS, Carvalheira JBC.
PMID: 33632534
Clin Nutr. 2021 Jun;40(6):4075-4084. doi: 10.1016/j.clnu.2021.02.010. Epub 2021 Feb 12.

BACKGROUND & AIMS: The use of computerized tomography to opportunistically assess body composition has highlighted abnormalities such as low muscle mass and high adiposity may be hidden conditions in cancer patients. However, the role of skeletal muscle (SM), subcutaneous...

Fatal cytokine release syndrome by an aberrant FLIP/STAT3 axis.

Cell death and differentiation

Musiu C, Caligola S, Fiore A, Lamolinara A, Frusteri C, Del Pizzo FD, De Sanctis F, Canè S, Adamo A, Hofer F, Barouni RM, Grilli A, Zilio S, Serafini P, Tacconelli E, Donadello K, Gottin L, Polati E, Girelli D, Polidoro I, Iezzi PA, Angelucci D, Capece A, Chen Y, Shi ZL, Murray PJ, Chilosi M, Amit I, Bicciato S, Iezzi M, Bronte V, Ugel S.
PMID: 34518653
Cell Death Differ. 2021 Sep 13; doi: 10.1038/s41418-021-00866-0. Epub 2021 Sep 13.

Inflammatory responses rapidly detect pathogen invasion and mount a regulated reaction. However, dysregulated anti-pathogen immune responses can provoke life-threatening inflammatory pathologies collectively known as cytokine release syndrome (CRS), exemplified by key clinical phenotypes unearthed during the SARS-CoV-2 pandemic. The...

Thyroid Eye Disease: Navigating the New Treatment Landscape.

Journal of the Endocrine Society

Dosiou C, Kossler AL.
PMID: 33948524
J Endocr Soc. 2021 Mar 17;5(5):bvab034. doi: 10.1210/jendso/bvab034. eCollection 2021 May 01.

Thyroid eye disease (TED) is a complex inflammatory disease that can have a long clinical course with sight-threatening and debilitating ocular sequelae. Until recently, there were limited therapeutic options available. In the last decade we have gained a deeper...

Enhanced discriminative fear learning of phobia-irrelevant stimuli in spider-fearful individuals.

Frontiers in behavioral neuroscience

Mosig C, Merz CJ, Mohr C, Adolph D, Wolf OT, Schneider S, Margraf J, Zlomuzica A.
PMID: 25324745
Front Behav Neurosci. 2014 Oct 01;8:328. doi: 10.3389/fnbeh.2014.00328. eCollection 2014.

Avoidance is considered as a central hallmark of all anxiety disorders. The acquisition and expression of avoidance, which leads to the maintenance and exacerbation of pathological fear is closely linked to Pavlovian and operant conditioning processes. Changes in conditionability...

Approach to the Adult Acute Lymphoblastic Leukemia Patient.

Journal of clinical medicine

Sas V, Moisoiu V, Teodorescu P, Tranca S, Pop L, Iluta S, Pasca S, Blag C, Man S, Roman A, Constantinescu C, Rus I, Buse M, Fetica B, Marian M, Selicean C, Berindan-Neagoe I, Petrushev B, Bumbea H, Tanase A, Zdrenghea M, Fuji S, Kitano S, Tomuleasa C.
PMID: 31390838
J Clin Med. 2019 Aug 06;8(8). doi: 10.3390/jcm8081175.

During recent decades, understanding of the molecular mechanisms of acute lymphoblastic leukemia (ALL) has improved considerably, resulting in better risk stratification of patients and increased survival rates. Age, white blood cell count (WBC), and specific genetic abnormalities are the...

The Influence of Methylating Mutations on Acute Myeloid Leukemia: Preliminary Analysis on 56 Patients.

Diagnostics (Basel, Switzerland)

Pasca S, Turcas C, Jurj A, Teodorescu P, Iluta S, Hotea I, Bojan A, Selicean C, Fetica B, Petrushev B, Moisoiu V, Zimta AA, Sas V, Constantinescu C, Zdrenghea M, Dima D, Tomuleasa C.
PMID: 32365516
Diagnostics (Basel). 2020 Apr 29;10(5). doi: 10.3390/diagnostics10050263.

Acute myeloid leukemia (AML) is a hematologic malignancy characterized by abnormal proliferation and a lack of differentiation of myeloid blasts. Considering the dismal prognosis this disease presents, several efforts have been made to better classify it and offer a...

The TABLET trial: limitations and implications.

BMC medicine

Dosiou C, Stagnaro-Green A.
PMID: 31288798
BMC Med. 2019 Jul 10;17(1):126. doi: 10.1186/s12916-019-1365-y.

No abstract available.

Showing 25 to 36 of 68 entries