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Showing 889 to 899 of 899 entries
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Improved outcomes with delayed admission to post-acute care: results of a natural experiment.

European geriatric medicine

McGettigan S, Farrell A, Murphy R, MacGearailt C, O'Keeffe ST, Mulkerrin EC.
PMID: 34313975
Eur Geriatr Med. 2021 Dec;12(6):1299-1302. doi: 10.1007/s41999-021-00545-w. Epub 2021 Jul 27.

PURPOSE: To determine the effectiveness of a post-acute care scheme by exploiting a natural experiment.METHODS: We used a reduction in funding for an Irish PAC scheme based in private nursing homes as a natural experiment to explore the effectiveness...

C-THAN: A new research center for the development of point-of-care technology for HIV/AIDS.

Global health innovation

McFall SM, Maiga M, Glucksberg MR, Palamountain KM, Achenbach CJ, Murphy RL.
PMID: 34278295
Glob Health Innov. 2019;2(2):1-5. doi: 10.15641/ghi.v2i2.822. Epub 2019 Nov 27.

The Center for Innovation in Point-of-Care Technologies for HIV/AIDS at Northwestern University (C-THAN) is a partner in the Point-of-Care Technologies Research Network (POCTRN) of the National Institutes of Biomedical Imaging and Bioengineering. POCTRN's mission is to drive the development...

Basic science approaches to common hand surgery problems.

The Journal of hand surgery, European volume

Wong J, Murphy M, Wu YF, Murphy R, Frueh FS, Farnebo S.
PMID: 34472390
J Hand Surg Eur Vol. 2021 Sep 02;17531934211042697. doi: 10.1177/17531934211042697. Epub 2021 Sep 02.

The field of hand surgery is constantly evolving to meet challenges of populations with increasing age and higher demands for active living. While our surgical care has improved over the last decades, it seems that future major improvement in...

"A Sign of Things to Come: Training Research Output Long-Term Scholarship in Academic Plastic Surgery.".

Aesthetic plastic surgery

Murphy AI, Mellia JA, Diatta F, Klifto KM, Morris MP, Fischer JP.
PMID: 33885940
Aesthetic Plast Surg. 2021 Apr 22; doi: 10.1007/s00266-021-02290-8. Epub 2021 Apr 22.

BACKGROUNDS: Academic plastic surgery has utilized different methods to promote early involvement of trainees in research. Further analysis is needed to characterize the effects of this early emphasis and their impact on long-term academic contributions to the field.METHODS: In...

Serum Symmetric Dimethylarginine Concentration in Greyhound Pups and Adults.

Topics in companion animal medicine

Couto CG, Murphy R, Coyne M, Drake C.
PMID: 34246821
Top Companion Anim Med. 2021 Nov;45:100558. doi: 10.1016/j.tcam.2021.100558. Epub 2021 Jul 08.

Greyhounds have developed numerous physiologic and hematologic adaptations specific to the breed. Adult Greyhounds have significantly higher serum creatinine (sCr) concentrations than non-Greyhound dogs; this is primarily attributed to their large muscle mass. Adult Greyhounds also have significantly higher...

The CREBRF diabetes-protective rs373863828-A allele is associated with enhanced early insulin release in men of Māori and Pacific ancestry.

Diabetologia

Burden HJ, Adams S, Kulatea B, Wright-McNaughton M, Sword D, Ormsbee JJ, Watene-O'Sullivan C, Merriman TR, Knopp JL, Chase JG, Krebs JD, Hall RM, Plank LD, Murphy R, Shepherd PR, Merry TL.
PMID: 34417843
Diabetologia. 2021 Dec;64(12):2779-2789. doi: 10.1007/s00125-021-05552-x. Epub 2021 Aug 21.

AIMS/HYPOTHESIS: The minor A allele of rs373863828 (CREBRF p.Arg457Gln) is associated with increased BMI, but reduced risk of type 2 and gestational diabetes in Polynesian (Pacific peoples and Aotearoa New Zealand Māori) populations. This study investigates the effect of...

Characterization, bio-uptake and toxicity of polymer-coated silver nanoparticles and their interaction with human peripheral blood mononuclear cells.

Beilstein journal of nanotechnology

Pourhoseini S, Enos RT, Murphy AE, Cai B, Lead JR.
PMID: 33842185
Beilstein J Nanotechnol. 2021 Mar 24;12:282-294. doi: 10.3762/bjnano.12.23. eCollection 2021.

Silver nanoparticles (AgNPs) are widely used in medical applications due to their antibacterial and antiviral properties. Despite the extensive study of AgNPs, their toxicity and their effect on human health is poorly understood, as a result of issues such...

Humanization of T cell-mediated immunity in mice.

Science immunology

Moore MJ, Zhong M, Hansen J, Gartner H, Grant C, Huang M, Harris FM, Tu N, Bowerman NA, Edelmann KH, Barry T, Herbin O, Tay CS, DiLillo DJ, Decker CE, Levenkova N, Shevchuk J, Dhanik A, Meagher KA, Karr A, Roos J, Lee WY, Suh D, Eckersdorff M, Meagher TC, Koss M, Esau L, Sleeman MA, Babb R, Chen G, Kyratsous CA, Poueymirou WT, McWhirter JR, Voronina VA, Guo C, Gurer C, Yancopoulos GD, Murphy AJ, Macdonald LE.
PMID: 34919442
Sci Immunol. 2021 Dec 17;6(66):eabj4026. doi: 10.1126/sciimmunol.abj4026. Epub 2021 Dec 17.

[Figure: see text].

Mammary tumour cells remodel the bone marrow vascular microenvironment to support metastasis.

Nature communications

Yip RKH, Rimes JS, Capaldo BD, Vaillant F, Mouchemore KA, Pal B, Chen Y, Surgenor E, Murphy AJ, Anderson RL, Smyth GK, Lindeman GJ, Hawkins ED, Visvader JE.
PMID: 34836954
Nat Commun. 2021 Nov 26;12(1):6920. doi: 10.1038/s41467-021-26556-6.

Bone marrow is a preferred metastatic site for multiple solid tumours and is associated with poor prognosis and significant morbidity. Accumulating evidence indicates that cancer cells colonise specialised niches within the bone marrow to support their long-term propagation, but...

KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma.

Nature communications

D'Oto A, Fang J, Jin H, Xu B, Singh S, Mullasseril A, Jones V, Abu-Zaid A, von Buttlar X, Cooke B, Hu D, Shohet J, Murphy AJ, Davidoff AM, Yang J.
PMID: 34893606
Nat Commun. 2021 Dec 10;12(1):7204. doi: 10.1038/s41467-021-27502-2.

The H3K27me2/me3 histone demethylase KDM6B is essential to neuroblastoma cell survival. However, the mechanism of KDM6B action remains poorly defined. We demonstrate that inhibition of KDM6B activity 1) reduces the chromatin accessibility of E2F target genes and MYCN, 2)...

Role of Low Molecular Weight Polymers on the Dynamics of Silicon Anodes During Casting.

Chemphyschem : a European journal of chemical physics and physical chemistry

Burdette-Trofimov MK, Armstrong BL, Murphy RP, Heroux L, Doucet M, Trask SE, Rogers AM, Veith GM.
PMID: 33848038
Chemphyschem. 2021 Jun 04;22(11):1049-1058. doi: 10.1002/cphc.202100179. Epub 2021 May 05.

This work probes the slurry architecture of a high silicon content electrode slurry with and without low molecular weight polymeric dispersants as a function of shear rate to mimic electrode casting conditions for poly(acrylic acid) (PAA) and lithium neutralized...

Showing 889 to 899 of 899 entries