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Showing 2209 to 2211 of 2211 entries
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Encephalitis patient-derived monoclonal GABAA receptor antibodies cause epileptic seizures.

The Journal of experimental medicine

Kreye J, Wright SK, van Casteren A, Stöffler L, Machule ML, Reincke SM, Nikolaus M, van Hoof S, Sanchez-Sendin E, Homeyer MA, Cordero Gómez C, Kornau HC, Schmitz D, Kaindl AM, Boehm-Sturm P, Mueller S, Wilson MA, Upadhya MA, Dhangar DR, Greenhill S, Woodhall G, Turko P, Vida I, Garner CC, Wickel J, Geis C, Fukata Y, Fukata M, Prüss H.
PMID: 34546336
J Exp Med. 2021 Nov 01;218(11). doi: 10.1084/jem.20210012. Epub 2021 Sep 21.

Autoantibodies targeting the GABAA receptor (GABAAR) hallmark an autoimmune encephalitis presenting with frequent seizures and psychomotor abnormalities. Their pathogenic role is still not well-defined, given the common overlap with further autoantibodies and the lack of patient-derived mAbs. Five GABAAR...

Impact of pre-treatment C-reactive protein level and skeletal muscle mass on outcomes after stereotactic body radiotherapy for T1N0M0 non-small cell lung cancer: a supplementary analysis of the Japan Clinical Oncology Group study JCOG0403.

Journal of radiation research

Matsuo Y, Nagata Y, Wakabayashi M, Ishikura S, Onishi H, Kokubo M, Karasawa K, Shioyama Y, Onimaru R, Hiraoka M.
PMID: 34350956
J Radiat Res. 2021 Sep 13;62(5):901-909. doi: 10.1093/jrr/rrab065.

This study aimed to evaluate the impact of pretreatment C-reactive protein (CRP) and skeletal muscle mass (SMM) on outcomes after stereotactic body radiotherapy (SBRT) for T1N0M0 non-small cell lung cancer (NSCLC) as a supplementary analysis of JCOG0403. Patients were...

Cyclin D2 Overexpression Enhances the Efficacy of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Myocardial Repair in a Swine Model of Myocardial Infarction.

Circulation

Zhao M, Nakada Y, Wei Y, Bian W, Chu Y, Borovjagin AV, Xie M, Zhu W, Nguyen T, Zhou Y, Serpooshan V, Walcott GP, Zhang J.
PMID: 33951921
Circulation. 2021 Jul 20;144(3):210-228. doi: 10.1161/CIRCULATIONAHA.120.049497. Epub 2021 May 06.

BACKGROUND: Human induced pluripotent stem cells with normal (wild-type) or upregulated (overexpressed) levels of CCND2 (cyclin D2) expression were differentiated into cardiomyocytes (CCND2METHODS: Acute myocardial infarction was induced by a 60-minute occlusion of the left anterior descending coronary artery....

Showing 2209 to 2211 of 2211 entries