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Showing 157 to 159 of 159 entries
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Physician Interpretation of Data of Uncertain Clinical Utility in Oncology Prescription Drug Promotion.

The oncologist

Boudewyns V, O'Donoghue AC, Paquin RS, Aikin KJ, Ferriola-Bruckenstein K, Scott VM.
PMID: 34510619
Oncologist. 2021 Dec;26(12):1071-1078. doi: 10.1002/onco.13972. Epub 2021 Sep 28.

BACKGROUND: Little is known about how physicians interpret data displays that depict preliminary or exploratory clinical data in physician-targeted sales aids for oncology drugs. Using three factorial experiments, we examined whether disclosures of data limitations and clinical uncertainty adequately...

Inhibition of p38 MAP kinase in patients with ST-elevation myocardial infarction - findings from the LATITUDE-TIMI 60 trial.

American heart journal

Cavender MA, O'Donoghue ML, Abbate A, Aylward P, Fox KA, Glaser RX, Park JG, Lopez-Sendon J, Steg PG, Sabatine MS, Morrow DA.
PMID: 34508693
Am Heart J. 2022 Jan;243:147-157. doi: 10.1016/j.ahj.2021.08.022. Epub 2021 Sep 08.

BACKGROUND: p38 mitogen activated kinase (MAPK) mediates the response to pro-inflammatory cytokines following myocardial infarction (MI) and is inhibited by losmapimod.METHODS: LATITUDE-TIMI 60 (ClinicalTrials.gov NCT02145468) randomized patients with MI to losmapimod or placebo for 12 weeks (24 weeks total...

Risk factors for type 2 MI: the usual suspects or guilt by association?.

European heart journal

O'Donoghue ML, Marston NA.
PMID: 34599595
Eur Heart J. 2022 Jan 13;43(2):136-137. doi: 10.1093/eurheartj/ehab707.

No abstract available.

Showing 157 to 159 of 159 entries