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Showing 25 to 36 of 233 entries
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Named Data Networking for Genomics Data Management and Integrated Workflows.

Frontiers in big data

Ogle C, Reddick D, McKnight C, Biggs T, Pauly R, Ficklin SP, Feltus FA, Shannigrahi S.
PMID: 33748749
Front Big Data. 2021 Feb 15;4:582468. doi: 10.3389/fdata.2021.582468. eCollection 2021.

Advanced imaging and DNA sequencing technologies now enable the diverse biology community to routinely generate and analyze terabytes of high resolution biological data. The community is rapidly heading toward the petascale in single investigator laboratory settings. As evidence, the...

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Ogle C, Reddick D, McKnight C, et al. Named Data Networking for Genomics Data Management and Integrated Workflows. Front Big Data. 2021;4:582468doi: 10.3389/fdata.2021.582468.
Ogle, C., Reddick, D., McKnight, C., Biggs, T., Pauly, R., Ficklin, S. P., Feltus, F. A., & Shannigrahi, S. (2021). Named Data Networking for Genomics Data Management and Integrated Workflows. Frontiers in big data, 4582468. https://doi.org/10.3389/fdata.2021.582468
Ogle, Cameron, et al. "Named Data Networking for Genomics Data Management and Integrated Workflows." Frontiers in big data vol. 4 (2021): 582468. doi: https://doi.org/10.3389/fdata.2021.582468
Ogle C, Reddick D, McKnight C, Biggs T, Pauly R, Ficklin SP, Feltus FA, Shannigrahi S. Named Data Networking for Genomics Data Management and Integrated Workflows. Front Big Data. 2021 Feb 15;4:582468. doi: 10.3389/fdata.2021.582468. eCollection 2021. PMID: 33748749; PMCID: PMC7968724.
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Measuring parent-adolescent interactions in natural habitats. The potential, status, and challenges of ecological momentary assessment.

Current opinion in psychology

Keijsers L, Boele S, Bülow A.
PMID: 34788708
Curr Opin Psychol. 2021 Oct 09;44:264-269. doi: 10.1016/j.copsyc.2021.10.002. Epub 2021 Oct 09.

Few people are as important for an adolescent's development as their parents. However, most research on parent-adolescent relationships describes long-term population-wide effects. Therefore, little is known about everyday interactions between adolescents and parents in individual families. Ecological momentary assessment...

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Keijsers L, Boele S, Bülow A. Measuring parent-adolescent interactions in natural habitats. The potential, status, and challenges of ecological momentary assessment. Curr Opin Psychol. 2021;44:264-269doi: 10.1016/j.copsyc.2021.10.002.
Keijsers, L., Boele, S., & Bülow, A. (2021). Measuring parent-adolescent interactions in natural habitats. The potential, status, and challenges of ecological momentary assessment. Current opinion in psychology, 44264-269. https://doi.org/10.1016/j.copsyc.2021.10.002
Keijsers, Loes, et al. "Measuring parent-adolescent interactions in natural habitats. The potential, status, and challenges of ecological momentary assessment." Current opinion in psychology vol. 44 (2021): 264-269. doi: https://doi.org/10.1016/j.copsyc.2021.10.002
Keijsers L, Boele S, Bülow A. Measuring parent-adolescent interactions in natural habitats. The potential, status, and challenges of ecological momentary assessment. Curr Opin Psychol. 2021 Oct 09;44:264-269. doi: 10.1016/j.copsyc.2021.10.002. Epub 2021 Oct 09. PMID: 34788708.
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Soil δ.

Scientific reports

Mullineaux ST, Kostka B, Rock L, Ogle N, Marks NJ, Doherty R, Harrod C, Montgomery WI, Scantlebury DM.
PMID: 34997035
Sci Rep. 2022 Jan 07;12(1):200. doi: 10.1038/s41598-021-04011-2.

Isotopic techniques have been used to study phenomena in the geological, environmental, and ecological sciences. For example, isotopic values of multiple elements elucidate the pathways energy and nutrients take in the environment. Isoscapes interpolate isotopic values across a geographical...

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Mullineaux ST, Kostka B, Rock L, et al. Soil δ. Sci Rep. 2022;12(1):200doi: 10.1038/s41598-021-04011-2.
Mullineaux, S. T., Kostka, B., Rock, L., Ogle, N., Marks, N. J., Doherty, R., Harrod, C., Montgomery, W. I., & Scantlebury, D. M. (2022). Soil δ. Scientific reports, 12(1), 200. https://doi.org/10.1038/s41598-021-04011-2
Mullineaux, Shay T, et al. "Soil δ." Scientific reports vol. 12,1 (2022): 200. doi: https://doi.org/10.1038/s41598-021-04011-2
Mullineaux ST, Kostka B, Rock L, Ogle N, Marks NJ, Doherty R, Harrod C, Montgomery WI, Scantlebury DM. Soil δ. Sci Rep. 2022 Jan 07;12(1):200. doi: 10.1038/s41598-021-04011-2. PMID: 34997035.
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Surgeon, patient, and caregiver perspective of pediatric surgical telemedicine in the COVID-19 pandemic era.

Pediatric surgery international

Diaz-Miron J, Ogle S, Kaizer A, Acker SN, Rove KO, Inge TH.
PMID: 34550442
Pediatr Surg Int. 2022 Feb;38(2):241-248. doi: 10.1007/s00383-021-05016-8. Epub 2021 Sep 22.

PURPOSE: Adoption of telemedicine (TME) in surgical specialties, prior to the COVID-19 pandemic, has previously been slow. The purpose of this prospective, observational, single institution study is to evaluate surgeon and caregiver perspectives of TMEs during the pandemic.METHODS: Surveys...

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Diaz-Miron J, Ogle S, Kaizer A, et al. Surgeon, patient, and caregiver perspective of pediatric surgical telemedicine in the COVID-19 pandemic era. Pediatr Surg Int. 2021;38(2):241-248doi: 10.1007/s00383-021-05016-8.
Diaz-Miron, J., Ogle, S., Kaizer, A., Acker, S. N., Rove, K. O., & Inge, T. H. (2022). Surgeon, patient, and caregiver perspective of pediatric surgical telemedicine in the COVID-19 pandemic era. Pediatric surgery international, 38(2), 241-248. https://doi.org/10.1007/s00383-021-05016-8
Diaz-Miron, Jose, et al. "Surgeon, patient, and caregiver perspective of pediatric surgical telemedicine in the COVID-19 pandemic era." Pediatric surgery international vol. 38,2 (2022): 241-248. doi: https://doi.org/10.1007/s00383-021-05016-8
Diaz-Miron J, Ogle S, Kaizer A, Acker SN, Rove KO, Inge TH. Surgeon, patient, and caregiver perspective of pediatric surgical telemedicine in the COVID-19 pandemic era. Pediatr Surg Int. 2022 Feb;38(2):241-248. doi: 10.1007/s00383-021-05016-8. Epub 2021 Sep 22. PMID: 34550442; PMCID: PMC8456071.
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Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy.

Genome research

Radke DW, Sul JH, Balick DJ, Akle S, Green RC, Sunyaev SR.
PMID: 33963077
Genome Res. 2021 Jun;31(6):935-946. doi: 10.1101/gr.275263.121. Epub 2021 May 07.

Genomic deletions provide a powerful loss-of-function model in noncoding regions to assess the role of purifying selection on genetic variation. Regulatory element function is characterized by nonuniform tissue and cell type activity, necessarily linking the study of fitness consequences...

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Radke DW, Sul JH, Balick DJ, et al. Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy. Genome Res. 2021;31(6):935-946doi: 10.1101/gr.275263.121.
Radke, D. W., Sul, J. H., Balick, D. J., Akle, S., Green, R. C., & Sunyaev, S. R. (2021). Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy. Genome research, 31(6), 935-946. https://doi.org/10.1101/gr.275263.121
Radke, David W, et al. "Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy." Genome research vol. 31,6 (2021): 935-946. doi: https://doi.org/10.1101/gr.275263.121
Radke DW, Sul JH, Balick DJ, Akle S, Green RC, Sunyaev SR. Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy. Genome Res. 2021 Jun;31(6):935-946. doi: 10.1101/gr.275263.121. Epub 2021 May 07. PMID: 33963077; PMCID: PMC8168579.
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3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation.

Cancer & metabolism

Skaripa-Koukelli I, Hauton D, Walsby-Tickle J, Thomas E, Owen J, Lakshminarayanan A, Able S, McCullagh J, Carlisle RC, Vallis KA.
PMID: 34649623
Cancer Metab. 2021 Oct 14;9(1):37. doi: 10.1186/s40170-021-00273-6.

BACKGROUND: Triple negative breast cancer (TNBC) poses a serious clinical challenge as it is an aggressive form of the disease that lacks estrogen receptor, progesterone receptor, and ERBB2 (formerly HER2) gene amplification, which limits the treatment options. The Warburg...

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Skaripa-Koukelli I, Hauton D, Walsby-Tickle J, et al. 3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation. Cancer Metab. 2021;9(1):37doi: 10.1186/s40170-021-00273-6.
Skaripa-Koukelli, I., Hauton, D., Walsby-Tickle, J., Thomas, E., Owen, J., Lakshminarayanan, A., Able, S., McCullagh, J., Carlisle, R. C., & Vallis, K. A. (2021). 3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation. Cancer & metabolism, 9(1), 37. https://doi.org/10.1186/s40170-021-00273-6
Skaripa-Koukelli, Irini, et al. "3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation." Cancer & metabolism vol. 9,1 (2021): 37. doi: https://doi.org/10.1186/s40170-021-00273-6
Skaripa-Koukelli I, Hauton D, Walsby-Tickle J, Thomas E, Owen J, Lakshminarayanan A, Able S, McCullagh J, Carlisle RC, Vallis KA. 3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation. Cancer Metab. 2021 Oct 14;9(1):37. doi: 10.1186/s40170-021-00273-6. PMID: 34649623; PMCID: PMC8515664.
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Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides.

Molecular pharmaceutics

Bavelaar BM, Song L, Jackson MR, Able S, Tietz O, Skaripa-Koukelli I, Waghorn PA, Gill MR, Carlisle RC, Tarsounas M, Vallis KA.
PMID: 34449222
Mol Pharm. 2021 Oct 04;18(10):3820-3831. doi: 10.1021/acs.molpharmaceut.1c00442. Epub 2021 Aug 27.

Telomerase represents an attractive target in oncology as it is expressed in cancer but not in normal tissues. The oligonucleotide inhibitors of telomerase represent a promising anticancer strategy, although poor cellular uptake can restrict their efficacy. In this study,...

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Bavelaar BM, Song L, Jackson MR, et al. Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides. Mol Pharm. 2021;18(10):3820-3831doi: 10.1021/acs.molpharmaceut.1c00442.
Bavelaar, B. M., Song, L., Jackson, M. R., Able, S., Tietz, O., Skaripa-Koukelli, I., Waghorn, P. A., Gill, M. R., Carlisle, R. C., Tarsounas, M., & Vallis, K. A. (2021). Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides. Molecular pharmaceutics, 18(10), 3820-3831. https://doi.org/10.1021/acs.molpharmaceut.1c00442
Bavelaar, Bas M, et al. "Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides." Molecular pharmaceutics vol. 18,10 (2021): 3820-3831. doi: https://doi.org/10.1021/acs.molpharmaceut.1c00442
Bavelaar BM, Song L, Jackson MR, Able S, Tietz O, Skaripa-Koukelli I, Waghorn PA, Gill MR, Carlisle RC, Tarsounas M, Vallis KA. Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides. Mol Pharm. 2021 Oct 04;18(10):3820-3831. doi: 10.1021/acs.molpharmaceut.1c00442. Epub 2021 Aug 27. PMID: 34449222; PMCID: PMC8493550.
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Optimization of critical parameters for coating of polymeric nanoparticles with plasma membrane vesicles by sonication.

Scientific reports

Yang F, Cabe MH, Ogle SD, Sanchez V, Langert KA.
PMID: 34907240
Sci Rep. 2021 Dec 14;11(1):23996. doi: 10.1038/s41598-021-03422-5.

Top-down functionalization of nanoparticles with cellular membranes imparts nanoparticles with enhanced bio-interfacing capabilities. Initial methods for membrane coating involved physical co-extrusion of nanoparticles and membrane vesicles through a porous membrane; however, recent works employ sonication as the disruptive force...

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Yang F, Cabe MH, Ogle SD, et al. Optimization of critical parameters for coating of polymeric nanoparticles with plasma membrane vesicles by sonication. Sci Rep. 2021;11(1):23996doi: 10.1038/s41598-021-03422-5.
Yang, F., Cabe, M. H., Ogle, S. D., Sanchez, V., & Langert, K. A. (2021). Optimization of critical parameters for coating of polymeric nanoparticles with plasma membrane vesicles by sonication. Scientific reports, 11(1), 23996. https://doi.org/10.1038/s41598-021-03422-5
Yang, Feipeng, et al. "Optimization of critical parameters for coating of polymeric nanoparticles with plasma membrane vesicles by sonication." Scientific reports vol. 11,1 (2021): 23996. doi: https://doi.org/10.1038/s41598-021-03422-5
Yang F, Cabe MH, Ogle SD, Sanchez V, Langert KA. Optimization of critical parameters for coating of polymeric nanoparticles with plasma membrane vesicles by sonication. Sci Rep. 2021 Dec 14;11(1):23996. doi: 10.1038/s41598-021-03422-5. PMID: 34907240; PMCID: PMC8671476.
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To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations.

PPAR research

Sullivan HJ, Wang X, Nogle S, Liao S, Wu C.
PMID: 32308671
PPAR Res. 2020 Apr 01;2020:5314187. doi: 10.1155/2020/5314187. eCollection 2020.

Chiglitazar is a promising new-generation insulin sensitizer with low reverse effects for the treatment of type II diabetes mellitus (T2DM) and has shown activity as a nonselective pan-agonist to the human peroxisome proliferator-activated receptors (PPARs) (i.e., full activation of...

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Sullivan HJ, Wang X, Nogle S, et al. To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations. PPAR Res. 2020;2020:5314187doi: 10.1155/2020/5314187.
Sullivan, H. J., Wang, X., Nogle, S., Liao, S., & Wu, C. (2020). To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations. PPAR research, 20205314187. https://doi.org/10.1155/2020/5314187
Sullivan, Holli-Joi, et al. "To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations." PPAR research vol. 2020 (2020): 5314187. doi: https://doi.org/10.1155/2020/5314187
Sullivan HJ, Wang X, Nogle S, Liao S, Wu C. To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations. PPAR Res. 2020 Apr 01;2020:5314187. doi: 10.1155/2020/5314187. eCollection 2020. PMID: 32308671; PMCID: PMC7152983.
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Real-world adherence and persistence with anaplastic lymphoma kinase inhibitors in nonsmall cell lung cancer.

Journal of managed care & specialty pharmacy

Ganti AK, Lin CW, Yang E, Wong WB, Ogale S.
PMID: 34913728
J Manag Care Spec Pharm. 2021 Dec 16;1-10. doi: 10.18553/jmcp.2021.21310. Epub 2021 Dec 16.

No abstract available.

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Ganti AK, Lin CW, Yang E, et al. Real-world adherence and persistence with anaplastic lymphoma kinase inhibitors in nonsmall cell lung cancer. J Manag Care Spec Pharm. 2021;1-10doi: 10.18553/jmcp.2021.21310.
Ganti, A. K., Lin, C. W., Yang, E., Wong, W. B., & Ogale, S. (2021). Real-world adherence and persistence with anaplastic lymphoma kinase inhibitors in nonsmall cell lung cancer. Journal of managed care & specialty pharmacy, 1-10. https://doi.org/10.18553/jmcp.2021.21310
Ganti, Apar Kishor, et al. "Real-world adherence and persistence with anaplastic lymphoma kinase inhibitors in nonsmall cell lung cancer." Journal of managed care & specialty pharmacy vol. (2021): 1-10. doi: https://doi.org/10.18553/jmcp.2021.21310
Ganti AK, Lin CW, Yang E, Wong WB, Ogale S. Real-world adherence and persistence with anaplastic lymphoma kinase inhibitors in nonsmall cell lung cancer. J Manag Care Spec Pharm. 2021 Dec 16;1-10. doi: 10.18553/jmcp.2021.21310. Epub 2021 Dec 16. PMID: 34913728.
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Patient-Reported Outcome Measures in Routine Pediatric Clinical Care: A Systematic Review.

Frontiers in pediatrics

Bele S, Chugh A, Mohamed B, Teela L, Haverman L, Santana MJ.
PMID: 32850521
Front Pediatr. 2020 Jul 28;8:364. doi: 10.3389/fped.2020.00364. eCollection 2020.

No abstract available.

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Bele S, Chugh A, Mohamed B, et al. Patient-Reported Outcome Measures in Routine Pediatric Clinical Care: A Systematic Review. Front Pediatr. 2020;8:364doi: 10.3389/fped.2020.00364.
Bele, S., Chugh, A., Mohamed, B., Teela, L., Haverman, L., & Santana, M. J. (2020). Patient-Reported Outcome Measures in Routine Pediatric Clinical Care: A Systematic Review. Frontiers in pediatrics, 8364. https://doi.org/10.3389/fped.2020.00364
Bele, Sumedh, et al. "Patient-Reported Outcome Measures in Routine Pediatric Clinical Care: A Systematic Review." Frontiers in pediatrics vol. 8 (2020): 364. doi: https://doi.org/10.3389/fped.2020.00364
Bele S, Chugh A, Mohamed B, Teela L, Haverman L, Santana MJ. Patient-Reported Outcome Measures in Routine Pediatric Clinical Care: A Systematic Review. Front Pediatr. 2020 Jul 28;8:364. doi: 10.3389/fped.2020.00364. eCollection 2020. PMID: 32850521; PMCID: PMC7399166.
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The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis.

Hepatology (Baltimore, Md.)

Barron-Millar B, Ogle L, Mells G, Flack S, Badrock J, Sandford R, Kirby J, Palmer J, Jopson L, Brain J, Smith GR, Rushton S, Hegade VS, Jones R, Rushbrook S, Thorburn D, Ryder S, Hirschfield G, Dyson JK, Jones DEJ.
PMID: 34129689
Hepatology. 2021 Dec;74(6):3269-3283. doi: 10.1002/hep.32011. Epub 2021 Nov 02.

BACKGROUND AND AIMS: Stratified therapy has entered clinical practice in primary biliary cholangitis (PBC), with routine use of second-line therapy in nonresponders to first-line therapy with ursodeoxycholic acid (UDCA). The mechanism for nonresponse to UDCA remains, however, unclear and...

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Barron-Millar B, Ogle L, Mells G, et al. The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis. Hepatology. 2021;74(6):3269-3283doi: 10.1002/hep.32011.
Barron-Millar, B., Ogle, L., Mells, G., Flack, S., Badrock, J., Sandford, R., Kirby, J., Palmer, J., Jopson, L., Brain, J., Smith, G. R., Rushton, S., Hegade, V. S., Jones, R., Rushbrook, S., Thorburn, D., Ryder, S., Hirschfield, G., Dyson, J. K., & Jones, D. E. J. (2021). The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis. Hepatology (Baltimore, Md.), 74(6), 3269-3283. https://doi.org/10.1002/hep.32011
Barron-Millar, Ben, et al. "The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis." Hepatology (Baltimore, Md.) vol. 74,6 (2021): 3269-3283. doi: https://doi.org/10.1002/hep.32011
Barron-Millar B, Ogle L, Mells G, Flack S, Badrock J, Sandford R, Kirby J, Palmer J, Jopson L, Brain J, Smith GR, Rushton S, Hegade VS, Jones R, Rushbrook S, Thorburn D, Ryder S, Hirschfield G, Dyson JK, Jones DEJ. The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis. Hepatology. 2021 Dec;74(6):3269-3283. doi: 10.1002/hep.32011. Epub 2021 Nov 02. PMID: 34129689.
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Showing 25 to 36 of 233 entries