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Showing 553 to 559 of 559 entries
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A PD-1 /PD-L1 proximity assay as a theranostic marker for PD-1 blockade in patients with metastatic melanoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Girault I, Adam J, Shen S, Roy S, Brard C, Faouzi S, Routier E, Lupu J, Warren S, Sorg K, Ong S, Morel P, Scoazec JY, Vagner S, Robert C.
PMID: 34785583
Clin Cancer Res. 2021 Nov 16; doi: 10.1158/1078-0432.CCR-21-1229. Epub 2021 Nov 16.

PURPOSE: Less than 50% of patients with melanoma respond to anti-PD1, and this treatment can induce severe toxicity. Predictive markers are thus needed to improve the benefit/risk ratio of immune checkpoint inhibitors (ICI). Baseline tumor parameters such as PD-L1...

Predictors of Postoperative Urinary Retention After Semiclosed Hemorrhoidectomy.

Annals of coloproctology

Jeong HY, Song SG, Lee JK.
PMID: 34284555
Ann Coloproctol. 2021 Jul 21; doi: 10.3393/ac.2021.00304.0043. Epub 2021 Jul 21.

PURPOSE: This study was performed to analyze the predictors that might contribute to urinary retention following semiclosed hemorrhoidectomy under spinal anesthesia.METHODS: This retrospective study enrolled 2,176 consecutive patients with symptomatic grade III to IV hemorrhoids who underwent semiclosed hemorrhoidectomy...

Complete Heart Block as a Clinical Feature in Critically Ill Coronavirus Disease 2019 (COVID-19) Patients: A Case Series of Three Cases.

Case reports in critical care

Ahmad F, Gandre P, Nguekam J, Wall A, Ong S, Karuppamakkantakath AN, Tasopoulos K, Sadiq MA, Kasim S, Cuesta JM.
PMID: 34422417
Case Rep Crit Care. 2021 Aug 11;2021:9955466. doi: 10.1155/2021/9955466. eCollection 2021.

No abstract available.

Reemerging Rice Orange Leaf Phytoplasma with Varying Symptoms Expressions and Its Transmission by a New Leafhopper Vector-.

Pathogens (Basel, Switzerland)

Jonson GB, Matres JM, Ong S, Tanaka T, Choi IR, Chiba S.
PMID: 33256154
Pathogens. 2020 Nov 26;9(12). doi: 10.3390/pathogens9120990.

Rice orange leaf phytoplasma (ROLP) belongs to the "

Screening of selected ageing-related proteins that extend chronological life span in yeast Saccharomyces cerevisiae.

Scientific reports

Lee JW, Ong TG, Samian MR, Teh AH, Watanabe N, Osada H, Ong EBB.
PMID: 34921163
Sci Rep. 2021 Dec 17;11(1):24148. doi: 10.1038/s41598-021-03490-7.

Ageing-related proteins play various roles such as regulating cellular ageing, countering oxidative stress, and modulating signal transduction pathways amongst many others. Hundreds of ageing-related proteins have been identified, however the functions of most of these ageing-related proteins are not...

Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages.

PLoS pathogens

Tran TT, Mathmann CD, Gatica-Andrades M, Rollo RF, Oelker M, Ljungberg JK, Nguyen TTK, Zamoshnikova A, Kummari LK, Wyer OJK, Irvine KM, Melo-Bolívar J, Gross A, Brown D, Mak JYW, Fairlie DP, Hansford KA, Cooper MA, Giri R, Schreiber V, Joseph SR, Simpson F, Barnett TC, Johansson J, Dankers W, Harris J, Wells TJ, Kapetanovic R, Sweet MJ, Latomanski EA, Newton HJ, Guérillot RJR, Hachani A, Stinear TP, Ong SY, Chandran Y, Hartland EL, Kobe B, Stow JL, Sauer-Eriksson AE, Begun J, Kling JC, Blumenthal A.
PMID: 35007292
PLoS Pathog. 2022 Jan 10;18(1):e1010166. doi: 10.1371/journal.ppat.1010166. eCollection 2022 Jan.

A hallmark of Listeria (L.) monocytogenes pathogenesis is bacterial escape from maturing entry vacuoles, which is required for rapid bacterial replication in the host cell cytoplasm and cell-to-cell spread. The bacterial transcriptional activator PrfA controls expression of key virulence...

Evaluation of teaching approach and student learning in a multidisciplinary sustainable engineering course.

Sharma B, Steward B, Ong SK, Miguez FE.
UIID-AD: 4296
2017;4032-4040. doi: 10.1016/j.jclepro.2016.10.046.

Teaching sustainability concepts to multidisciplinary classes of engineering students is challenging due to their diverse background and discipline-specific skill set and the interdisciplinary nature of the sustainability issues at stake. The present study was conducted to understand the challenges...

Showing 553 to 559 of 559 entries