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Showing 493 to 503 of 503 entries
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A Japanese family with a heterozygous novel mutation in the Indian hedgehog gene exhibiting a broad spectrum of clinical features and radiological findings.

Congenital anomalies

Onuki T, Shibata N, Hiroshima S, Sawano K, Nagasaki K.
PMID: 34591992
Congenit Anom (Kyoto). 2022 Jan;62(1):47-48. doi: 10.1111/cga.12445. Epub 2021 Oct 12.

No abstract available.

Precise Measurement of the D^{0} and D^{+} Lifetimes at Belle II.

Physical review letters

Abudinén F, Adachi I, Adamczyk K, Aggarwal L, Ahmed H, Aihara H, Akopov N, Aloisio A, Anh Ky N, Asner DM, Atmacan H, Aushev V, Babu V, Bacher S, Bae H, Baehr S, Bahinipati S, Bambade P, Banerjee S, Bansal S, Barrett M, Baudot J, Bauer M, Baur A, Becker J, Behera PK, Bennett JV, Bernieri E, Bernlochner FU, Bertemes M, Bertholet E, Bessner M, Bettarini S, Bhardwaj V, Bianchi F, Bilka T, Bilokin S, Biswas D, Bobrov A, Bodrov D, Bolz A, Bozek A, Bračko M, Branchini P, Braun N, Briere RA, Browder TE, Budano A, Bussino S, Campajola M, Cao L, Casarosa G, Cecchi C, Červenkov D, Chang MC, Chang P, Cheaib R, Chekelian V, Chen C, Chen YT, Cheon BG, Chilikin K, Chirapatpimol K, Cho HE, Cho K, Cho SJ, Choi SK, Choudhury S, Cinabro D, Corona L, Cremaldi LM, Cunliffe S, Czank T, Dattola F, De La Cruz-Burelo E, de Marino G, De Nardo G, De Pietro G, de Sangro R, Destefanis M, Dey S, De Yta-Hernandez A, Di Canto A, Di Capua F, Dingfelder J, Doležal Z, Domínguez Jiménez I, Dong TV, Dorigo M, Dort K, Dossett D, Dubey S, Duell S, Dujany G, Ecker P, Epifanov D, Ferber T, Ferlewicz D, Finocchiaro G, Flood K, Fodor A, Forti F, Fulsom BG, Gabrielli A, Gabyshev N, Gaz A, Gellrich A, Giakoustidis G, Giordano R, Giri A, Glazov A, Gobbo B, Godang R, Goldenzweig P, Golob B, Gradl W, Graziani E, Greenwald D, Gu T, Guan Y, Gudkova K, Guilliams J, Hadjivasiliou C, Halder S, Hara K, Hara T, Hartbrich O, Hayasaka K, Hayashii H, Hazra S, Hearty C, Heredia de la Cruz I, Hernández Villanueva M, Hershenhorn A, Higuchi T, Hill EC, Hirata H, Hoek M, Hohmann M, Hsu CL, Humair T, Iijima T, Inami K, Inguglia G, Ishikawa A, Itoh R, Iwasaki M, Iwasaki Y, Jacobs WW, Jaffe DE, Jang EJ, Jia S, Jin Y, Junkerkalefeld H, Kakuno H, Kaliyar AB, Kandra J, Kang KH, Karl R, Karyan G, Kato Y, Kawasaki T, Kiesling C, Kim CH, Kim DY, Kim YK, Kim Y, Kimmel TD, Kinoshita K, Kodyš P, Koga T, Kohani S, Konno T, Korpar S, Kovalenko E, Kowalewski R, Kraetzschmar TMG, Krinner F, Križan P, Krokovny P, Kuhr T, Kumar J, Kumar M, Kumar R, Kumara K, Kurz S, Kuzmin A, Kwon YJ, Lacaprara S, Lalwani K, Lam T, Lanceri L, Lange JS, Laurenza M, Lautenbach K, Le Diberder FR, Lee SC, Leitl P, Levit D, Li C, Li LK, Libby J, Lieret K, Liptak Z, Liu QY, Liventsev D, Longo S, Lueck T, Lyu C, Manfredi R, Manoni E, Marinas C, Martini A, Matsuda T, Matsuoka K, Matvienko D, McKenna JA, Meier F, Merola M, Metzner F, Miller C, Miyabayashi K, Mizuk R, Mohanty GB, Molina-Gonzalez N, Moon H, Moser HG, Mrvar M, Murphy C, Mussa R, Nakamura I, Nakamura KR, Nakao M, Nakazawa H, Natkaniec Z, Natochii A, Nazaryan G, Niebuhr C, Niiyama M, Nisar NK, Nishida S, Nishimura K, Ogawa S, Onishchuk Y, Ono H, Onuki Y, Oskin P, Oxford ER, Ozaki H, Pakhlov P, Paladino A, Pang T, Panta A, Paoloni E, Pardi S, Park H, Park SH, Paschen B, Passeri A, Pathak A, Patra S, Paul S, Pedlar TK, Peruzzi I, Peschke R, Pestotnik R, Pham F, Piccolo M, Piilonen LE, Pinna Angioni G, Podesta-Lerma PLM, Podobnik T, Pokharel S, Polat G, Popov V, Praz C, Prell S, Prencipe E, Prim MT, Purohit MV, Purwar H, Rad N, Rados P, Raiz S, Reiter S, Remnev M, Ripp-Baudot I, Rizzo G, Rizzuto LB, Robertson SH, Roney JM, Rostomyan A, Rout N, Rozanska M, Sahoo D, Sanders DA, Sandilya S, Sangal A, Santelj L, Sato Y, Savinov V, Scavino B, Schueler J, Schwanda C, Schwartz AJ, Seino Y, Selce A, Senyo K, Serrano J, Sfienti C, Shiu JG, Shwartz B, Sibidanov A, Simon F, Sobie RJ, Soffer A, Sokolov A, Solovieva E, Spataro S, Spruck B, Starič M, Stefkova S, Stottler ZS, Stroili R, Strube J, Sumihama M, Sutcliffe W, Suzuki SY, Svidras H, Tabata M, Takizawa M, Tamponi U, Tanaka S, Tanida K, Tanigawa H, Taniguchi N, Tenchini F, Tiwary R, Tonelli D, Torassa E, Toutounji N, Trabelsi K, Tsuboyama T, Ueda I, Uehara S, Uematsu Y, Uglov T, Unger K, Unno Y, Uno K, Uno S, Urquijo P, Ushiroda Y, Usov YV, Vahsen SE, van Tonder R, Varner GS, Vinokurova A, Vitale L, Vossen A, Waheed E, Wakeling HM, Wang E, Wang MZ, Wang XL, Warburton A, Watanabe M, Welsch M, Wessel C, Wiechczynski J, Won E, Xu XP, Yabsley BD, Yamada S, Yan W, Yang SB, Ye H, Yelton J, Yin JH, Yoshihara K, Yusa Y, Zani L, Zhilich V, Zhou QD, Zhou XY, Zhukova VI, Žlebčík R.
PMID: 34860075
Phys Rev Lett. 2021 Nov 19;127(21):211801. doi: 10.1103/PhysRevLett.127.211801.

We report a measurement of the D^{0} and D^{+} lifetimes using D^{0}→K^{-}π^{+} and D^{+}→K^{-}π^{+}π^{+} decays reconstructed in e^{+}e^{-}→cc[over ¯] data recorded by the Belle II experiment at the SuperKEKB asymmetric-energy e^{+}e^{-} collider. The data, collected at center-of-mass energies at...

Analysis of Nanoscratch Mechanism of C-Plane Sapphire with the Aid of Molecular Dynamics Simulation of Hcp Crystal.

Nanomaterials (Basel, Switzerland)

Lin W, Yano N, Shimizu J, Zhou L, Onuki T, Ojima H.
PMID: 34361124
Nanomaterials (Basel). 2021 Jul 01;11(7). doi: 10.3390/nano11071739.

In this study, single groove nanoscratch experiments using a friction force microscope (FFM) with a monocrystalline diamond tip were conducted on a c-plane sapphire wafer to analyze the ductile-regime removal and deformation mechanism including the anisotropy. Various characteristics, such...

Bioinspired carbon monoxide delivery using artificial blood attenuates the progression of obliterative bronchiolitis via suppression of macrophage activation by IL-17A.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Watabe Y, Taguchi K, Sakai H, Enoki Y, Maruyama T, Otagiri M, Kohno M, Matsumoto K.
PMID: 34864198
Eur J Pharm Biopharm. 2022 Jan;170:43-51. doi: 10.1016/j.ejpb.2021.11.011. Epub 2021 Dec 02.

Carbon monoxide (CO) is expected to attenuate the progression of obliterative bronchiolitis (OB), which is a serious complication after lung transplantation. However, issues in terms of feasible exogenous CO supply, such as continuousness and safety, remain unsolved. Here, we...

Morpho-physiological and molecular mechanisms of phenotypic root plasticity for rice adaptation to water stress conditions.

Breeding science

Lucob-Agustin N, Kawai T, Kano-Nakata M, Suralta RR, Niones JM, Hasegawa T, Inari-Ikeda M, Yamauchi A, Inukai Y.
PMID: 33762873
Breed Sci. 2021 Feb;71(1):20-29. doi: 10.1270/jsbbs.20106. Epub 2021 Jan 30.

Different types of water stress severely affect crop production, and the plant root system plays a critical role in stress avoidance. In the case of rice, a cereal crop cultivated under the widest range of soil hydrologic conditions, from...

Dopaminergic restoration of prefrontal cortico-putaminal network in gene therapy for aromatic l-amino acid decarboxylase deficiency.

Brain communications

Onuki Y, Ono S, Nakajima T, Kojima K, Taga N, Ikeda T, Kuwajima M, Kurokawa Y, Kato M, Kawai K, Osaka H, Sato T, Muramatsu SI, Yamagata T.
PMID: 34423296
Brain Commun. 2021 Apr 15;3(3):fcab078. doi: 10.1093/braincomms/fcab078. eCollection 2021.

Aromatic l-amino acid decarboxylase (AADC) is an essential dopamine-synthesizing enzyme. In children with AADC deficiency, the gene delivery of AADC into the putamen, which functionally interacts with cortical regions, was found to improve motor function and ameliorate dystonia. However,...

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced Histone Acetylation via α7nAChR-Mediated PI3K/Akt Activation and Its Impact on γ-H2AX Generation.

Chemical research in toxicology

Shikata M, Toyooka T, Komaki Y, Ibuki Y.
PMID: 34784199
Chem Res Toxicol. 2021 Dec 20;34(12):2512-2521. doi: 10.1021/acs.chemrestox.1c00287. Epub 2021 Nov 16.

A typical tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is known as a strong carcinogen. We previously reported that metabolized NNK induced histone H2AX phosphorylation (γ-H2AX), a DNA damage-induced histone modification. In this study, we found that NNK globally acetylated histone H3,...

Guide sheath breakage during endobronchial ultrasonography.

Respirology case reports

Yanagihara T, Yamaoka M, Kawakami N, Onuki T, Inagaki M.
PMID: 33251013
Respirol Case Rep. 2020 Nov 20;9(1):e00690. doi: 10.1002/rcr2.690. eCollection 2021 Jan.

This report describes a case of guide sheath breakage during endobronchial ultrasonography. While steering the guide sheath in the direction of a peripheral lung nodule using a guiding device/curette, the radiopaque band (RB) attached to the head of the...

Contribution of non-sensory neurons in visual cortical areas to visually guided decisions in the rat.

Current biology : CB

Osako Y, Ohnuki T, Tanisumi Y, Shiotani K, Manabe H, Sakurai Y, Hirokawa J.
PMID: 33891892
Curr Biol. 2021 Jul 12;31(13):2757-2769.e6. doi: 10.1016/j.cub.2021.03.099. Epub 2021 Apr 22.

It is widely assumed that trial-by-trial variability in visual detection performance is explained by the fidelity of visual responses in visual cortical areas influenced by fluctuations of internal states, such as vigilance and behavioral history. However, it is not...

Targeting Amino Acid Metabolic Reprogramming via L-Type Amino Acid Transporter 1 (LAT1) for Endocrine-Resistant Breast Cancer.

Cancers

Shindo H, Harada-Shoji N, Ebata A, Sato M, Soga T, Miyashita M, Tada H, Kawai M, Kosaka S, Onuki K, Usami S, Furumoto S, Hayashi S, Abe T, Suzuki T, Ishida T, Sasano H.
PMID: 34503187
Cancers (Basel). 2021 Aug 30;13(17). doi: 10.3390/cancers13174375.

The PI3K/Akt/mTOR pathway has been well known to interact with the estrogen receptor (ER)-pathway and to be also frequently upregulated in aromatase inhibitor (AI)-resistant breast cancer patients. Intracellular levels of free amino acids, especially leucine, regulate the mammalian target...

Asthma caused by durvalumab after chemoradiotherapy in two patients with non-small cell lung cancer.

Respirology case reports

Uemura T, Fukumitsu K, Maeno K, Fukuda S, Onuki T, Kanemitsu Y, Oguri T, Niimi A, Hida T.
PMID: 34457312
Respirol Case Rep. 2021 Aug 19;9(9):e0835. doi: 10.1002/rcr2.835. eCollection 2021 Sep.

Durvalumab, an anti-programmed cell death-ligand 1 (PD-L1) antibody, is currently used in the maintenance therapy for patients with stage III non-small cell lung cancer after platinum-based chemoradiotherapy. A 69-year-old male with lung adenocarcinoma, clinical stage IIIA, was treated with...

Showing 493 to 503 of 503 entries