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Showing 13 to 24 of 37 entries
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Association between neutrophil-to-lymphocyte ratio in the first seven days of sepsis and mortality.

Enfermedades infecciosas y microbiologia clinica (English ed.)

Lorente L, Martín MM, Ortiz-López R, Alvarez-Castillo A, Ruiz C, Uribe L, González-Rivero AF, Pérez-Cejas A, Jiménez A.
PMID: 33384188
Enferm Infecc Microbiol Clin (Engl Ed). 2020 Dec 28; doi: 10.1016/j.eimc.2020.11.004. Epub 2020 Dec 28.

INTRODUCTION: The neutrophil-to-lymphocyte ratio (NLR) in the diagnosis of sepsis has been found to be higher in non-survivors than in survivors, and that is associated with mortality. A higher NLR in non-survivors than in survivors has been reported in...

Mortality of spontaneous intracerebral haemorrhage patients and high serum caspase-8 concentrations.

Anaesthesia, critical care & pain medicine

Lorente L, Martín MM, González-Rivero AF, Ramos-Gómez L, Sole-Violan J, Cáceres JJ, Villacampa-Jiménez JJ, Jiménez A, Pérez-Cejas A.
PMID: 34718185
Anaesth Crit Care Pain Med. 2021 Oct 27;40(6):100969. doi: 10.1016/j.accpm.2021.100969. Epub 2021 Oct 27.

PURPOSE: Apoptotic changes in brain samples have been found in haematoma areas of patients with spontaneous intracerebral haemorrhage (SIH) undergoing surgical haematoma evacuation. However, circulating caspase-8 concentrations in SIH patients have not been described. Thus, we carried out this...

Transcriptome Analysis Identifies GATA3-AS1 as a Long Noncoding RNA Associated with Resistance to Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer Patients.

The Journal of molecular diagnostics : JMD

Contreras-Espinosa L, Alcaraz N, De La Rosa-Velázquez IA, Díaz-Chávez J, Cabrera-Galeana P, Rebollar-Vega R, Reynoso-Noverón N, Maldonado-Martínez HA, González-Barrios R, Montiel-Manríquez R, Bautista-Sánchez D, Castro-Hernández C, Alvarez-Gomez RM, Jiménez-Trejo F, Tapia-Rodríguez M, García-Gordillo JA, Pérez-Rosas A, Bargallo-Rocha E, Arriaga-Canon C, Herrera LA.
PMID: 34358678
J Mol Diagn. 2021 Oct;23(10):1306-1323. doi: 10.1016/j.jmoldx.2021.07.014. Epub 2021 Aug 04.

Breast cancer is one of the leading causes of mortality in women worldwide, and neoadjuvant chemotherapy has emerged as an option for the management of locally advanced breast cancer. Extensive efforts have been made to identify new molecular markers...

Association of serum soluble Fas concentrations and mortality of septic patients.

Enfermedades infecciosas y microbiologia clinica (English ed.)

Lorente L, Martín MM, Ortiz-López R, González-Rivero AF, Pérez-Cejas A, Pastor E, Domínguez-Curell C, Raja L, Lorenzo L, Jiménez A.
PMID: 34865710
Enferm Infecc Microbiol Clin (Engl Ed). 2021 Dec;39(10):493-497. doi: 10.1016/j.eimce.2020.08.007.

INTRODUCTION: Scarce data on Fas, one of the main receptors that activates the apoptosis extrinsic pathway, in septic patients exists. Higher blood soluble Fas (sFas) concentrations in non-survivor septic patients compared with survivors have been found in small studies;...

Association between serum concentrations of anti-apoptotic B-cell lymphoma-2 protein and traumatic brain injury mortality.

Expert review of molecular diagnostics

Lorente L, Martín MM, González-Rivero AF, Pérez-Cejas A, Ramos-Gómez L, Solé-Violán J, Cáceres JJ, Ferrer-Moure C, Jiménez A.
PMID: 34878357
Expert Rev Mol Diagn. 2021 Dec 22;1-5. doi: 10.1080/14737159.2022.2016394. Epub 2021 Dec 22.

BACKGROUND: There are scarce and contradictory data existing about B-cell lymphoma 2 (Bcl2), one of the Bcl2 family of anti-apoptotic proteins, in traumatic brain injury (TBI) patients. Thus, the objective of this study was to analyze whether blood concentrations...

Serum caspase-3 levels during the first week of traumatic brain injury.

Medicina intensiva

Lorente L, Martín MM, Pérez-Cejas A, González-Rivero AF, Argueso M, Ramos L, Solé-Violán J, Cáceres JJ, Jiménez A, García-Marín V.
PMID: 31677852
Med Intensiva (Engl Ed). 2021 Apr;45(3):131-137. doi: 10.1016/j.medin.2019.09.005. Epub 2019 Oct 31.

OBJECTIVE: Confluence between the intrinsic and extrinsic apoptosis pathways is reached at the point of caspase-3 activation, which induces death cell. Higher serum caspase-3 levels have been recorded on day 1 of traumatic brain injury (TBI) in 30-day non-survivors...

Nanoscale conductive pattern of the homoepitaxial AlGaN/GaN transistor.

Nanotechnology

Pérez-Tomás A, Catalàn G, Fontserè A, Iglesias V, Chen H, Gammon PM, Jennings MR, Thomas M, Fisher CA, Sharma YK, Placidi M, Chmielowska M, Chenot S, Porti M, Nafría M, Cordier Y.
PMID: 25719801
Nanotechnology. 2015 Mar 20;26(11):115203. doi: 10.1088/0957-4484/26/11/115203. Epub 2015 Feb 26.

The gallium nitride (GaN)-based buffer/barrier mode of growth and morphology, the transistor electrical response (25-310 °C) and the nanoscale pattern of a homoepitaxial AlGaN/GaN high electron mobility transistor (HEMT) have been investigated at the micro and nanoscale. The low...

Early Mortality of Brain Infarction Patients and Red Blood Cell Distribution Width.

Brain sciences

Lorente L, Martín MM, Abreu-González P, Pérez-Cejas A, González-Rivero AF, Ramos-Gómez L, Argueso M, Solé-Violán J, Cáceres JJ, Jiménez A, García-Marín V.
PMID: 32224967
Brain Sci. 2020 Mar 26;10(4). doi: 10.3390/brainsci10040196.

BACKGROUND: Meta-analysis has found that high baseline red blood cell distribution width (RDW) is associated with increased long-term mortality (mortality at one year or more) in ischemic stroke. The objectives of this study were to determine whether there is...

High Serum Caspase-Cleaved Cytokeratin-18 Levels and Mortality of Traumatic Brain Injury Patients.

Brain sciences

Lorente L, Martín MM, González-Rivero AF, Pérez-Cejas A, Argueso M, Ramos L, Solé-Violán J, Cáceres JJ, Jiménez A, García-Marín V.
PMID: 31658711
Brain Sci. 2019 Oct 10;9(10). doi: 10.3390/brainsci9100269.

OBJECTIVE: Apoptosis increases in traumatic brain injury (TBI). Caspase-cleaved cytokeratin (CCCK)-18 in blood during apoptosis could appear. At the time of admission due to TBI, higher blood CCCK-18 levels were found in non-surviving than in surviving patients. Therefore, the...

Blood caspase-8 concentrations and mortality among septic patients.

Medicina intensiva

Lorente L, Martín MM, Ortiz-López R, González-Rivero AF, Pérez-Cejas A, Martín M, Gonzalez V, Pérez A, Rodin M, Jiménez A.
PMID: 32843190
Med Intensiva (Engl Ed). 2020 Aug 22; doi: 10.1016/j.medin.2020.06.016. Epub 2020 Aug 22.

OBJECTIVE: No data are available on blood caspase-8 concentrations (the initiator caspase in the extrinsic apoptosis pathway) in septic patients. The present study thus describes the blood caspase-8 concentrations in survivors and non-survivors, and examines the possible association between...

Interkingdom Gut Microbiome and Resistome of the Cockroach .

mSystems

Domínguez-Santos R, Pérez-Cobas AE, Cuti P, Pérez-Brocal V, García-Ferris C, Moya A, Latorre A, Gil R.
PMID: 33975971
mSystems. 2021 May 11;6(3). doi: 10.1128/mSystems.01213-20.

Cockroaches are intriguing animals with two coexisting symbiotic systems, an endosymbiont in the fat body, involved in nitrogen metabolism, and a gut microbiome whose diversity, complexity, role, and developmental dynamics have not been fully elucidated. In this work, we...

Association between blood caspase-8 levels and mortality of patients with malignant middle cerebral artery infarction.

Medicina intensiva

Lorente L, Martín MM, Pérez-Cejas A, González-Rivero AF, Ramos-Gómez L, Solé-Violán J, Cáceres JJ, Villacampa-Jiménez JJ, Jiménez A.
PMID: 33926751
Med Intensiva (Engl Ed). 2021 Apr 26; doi: 10.1016/j.medin.2021.03.001. Epub 2021 Apr 26.

OBJECTIVE: High concentrations of caspase-8 (main initiator caspase of apoptosis extrinsic pathway) have been found in brain tissue from traumatic brain injury patients and in blood of patients with different diseases. However, there are not data on blood caspase-8...

Showing 13 to 24 of 37 entries