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Showing 25 to 36 of 37 entries
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Non-Survivor Ischemic Stroke Patients Maintain High Serum Caspase-Cleaved Cytokeratin-18 Levels.

Brain sciences

Lorente L, Martín MM, Pérez-Cejas A, González-Rivero AF, Sabatel R, Ramos L, Argueso M, Solé-Violán J, Cáceres JJ, Jiménez A, García-Marín V.
PMID: 32120809
Brain Sci. 2020 Feb 27;10(3). doi: 10.3390/brainsci10030132.

OBJECTIVE: Caspase-cleaved cytokeratin (CCCK)-18 could appear in blood during apoptosis. In two different studies, on day 1 of cerebral infarction and at 72 hours of cerebral infarction, respectively, higher circulating CCCK-18 levels were found in non-surviving than in surviving...

Rare Variants in 48 Genes Account for 42% of Cases of Epilepsy With or Without Neurodevelopmental Delay in 246 Pediatric Patients.

Frontiers in neuroscience

Fernández-Marmiesse A, Roca I, Díaz-Flores F, Cantarín V, Pérez-Poyato MS, Fontalba A, Laranjeira F, Quintans S, Moldovan O, Felgueroso B, Rodríguez-Pedreira M, Simón R, Camacho A, Quijada P, Ibanez-Mico S, Domingno MR, Benito C, Calvo R, Pérez-Cejas A, Carrasco ML, Ramos F, Couce ML, Ruiz-Falcó ML, Gutierrez-Solana L, Martínez-Atienza M.
PMID: 31780880
Front Neurosci. 2019 Nov 08;13:1135. doi: 10.3389/fnins.2019.01135. eCollection 2019.

In order to characterize the genetic architecture of epilepsy in a pediatric population from the Iberian Peninsula (including the Canary Islands), we conducted targeted exome sequencing of 246 patients with infantile-onset seizures with or without neurodevelopmental delay. We detected...

Traumatic Brain Injury Patients Mortality and Serum Total Antioxidant Capacity.

Brain sciences

Lorente L, Martín MM, Pérez-Cejas A, González-Rivero AF, Abreu-González P, Ramos L, Argueso M, Solé-Violán J, Cáceres JJ, Jiménez A, García-Marín V.
PMID: 32085496
Brain Sci. 2020 Feb 18;10(2). doi: 10.3390/brainsci10020110.

OBJECTIVE: Oxidation is involved in secondary brain injury after traumatic brain injury (TBI). Increased concentrations of total antioxidant capacity (TAC) in blood at the time of admission for TBI have been found in non-surviving patients. The main objective of...

Serum tissue inhibitor of MMP-1 levels at any moment of the first week of spontaneous intracerebral hemorrhage may predict early mortality.

Biomarkers in medicine

Lorente L, Martín MM, Pérez-Cejas A, González-Rivero AF, Sabatel R, Ramos-Gómez L, Argueso M, Solé-Violán J, Cáceres JJ, Jiménez A.
PMID: 34488441
Biomark Med. 2021 Oct;15(14):1245-1251. doi: 10.2217/bmm-2020-0859. Epub 2021 Sep 07.

No abstract available.

Feasibility, tolerability, and efficacy of the concurrent addition of erlotinib to thoracic radiotherapy in locally advanced unresectable non-small-cell lung cancer: a Phase II trial.

OncoTargets and therapy

Martínez E, Martínez M, Rico M, Hernández B, Casas F, Viñolas N, Pérez-Casas A, Dómine M, Mínguez J.
PMID: 27042098
Onco Targets Ther. 2016 Mar 01;9:1057-66. doi: 10.2147/OTT.S89755. eCollection 2016.

PURPOSE: Although many studies have confirmed the synergic effects of combining chemotherapy (CT) and radiotherapy (RT), clinical data evaluating safety and efficacy of erlotinib in combination with RT in locally advanced non-small-cell lung cancer (NSCLC) are limited. The aim...

Mortality of spontaneous intracerebral haemorrhage patients and high serum caspase-8 concentrations.

Anaesthesia, critical care & pain medicine

Lorente L, Martín MM, González-Rivero AF, Ramos-Gómez L, Sole-Violan J, Cáceres JJ, Villacampa-Jiménez JJ, Jiménez A, Pérez-Cejas A.
PMID: 34718185
Anaesth Crit Care Pain Med. 2021 Oct 27;40(6):100969. doi: 10.1016/j.accpm.2021.100969. Epub 2021 Oct 27.

PURPOSE: Apoptotic changes in brain samples have been found in haematoma areas of patients with spontaneous intracerebral haemorrhage (SIH) undergoing surgical haematoma evacuation. However, circulating caspase-8 concentrations in SIH patients have not been described. Thus, we carried out this...

Status and Prospects of Cubic Silicon Carbide Power Electronics Device Technology.

Materials (Basel, Switzerland)

Li F, Roccaforte F, Greco G, Fiorenza P, La Via F, Pérez-Tomas A, Evans JE, Fisher CA, Monaghan FA, Mawby PA, Jennings M.
PMID: 34640228
Materials (Basel). 2021 Oct 05;14(19). doi: 10.3390/ma14195831.

Wide bandgap (WBG) semiconductors are becoming more widely accepted for use in power electronics due to their superior electrical energy efficiencies and improved power densities. Although WBG cubic silicon carbide (3C-SiC) displays a modest bandgap compared to its commercial...

Sustainable plant-based diets promote rainbow trout gut microbiota richness and do not alter resistance to bacterial infection.

Animal microbiome

Pérez-Pascual D, Pérez-Cobas AE, Rigaudeau D, Rochat T, Bernardet JF, Skiba-Cassy S, Marchand Y, Duchaud E, Ghigo JM.
PMID: 34225826
Anim Microbiome. 2021 Jul 05;3(1):47. doi: 10.1186/s42523-021-00107-2.

BACKGROUND: Farmed fish food with reduced fish-derived products are gaining growing interest due to the ecological impact of fish-derived protein utilization and the necessity to increase aquaculture sustainability. Although different terrestrial plant proteins could replace fishmeal proteins, their use...

Mortality prediction of patients with spontaneous intracerebral hemorrhage by serum soluble Fas Ligand concentrations.

Expert review of molecular diagnostics

Lorente L, Martín MM, Pérez-Cejas A, González-Rivero AF, Ramos-Gómez L, Solé-Violán J, Cáceres JJ, Cabrera J, Uribe L, Ferrer-Moure C, Jiménez A.
PMID: 34894981
Expert Rev Mol Diagn. 2021 Dec 11; doi: 10.1080/14737159.2022.2017775. Epub 2021 Dec 11.

BACKGROUND: A study of patients with spontaneous intracerebral hemorrhage (SIH) found a higher content of Fas ligand in the perihematomic brain area compared to healthy brain areas. However, there is no data about the potential role of blood FasL...

Blood caspase-8 concentrations and mortality among septic patients.

Medicina intensiva

Lorente L, Martín MM, Ortiz-López R, González-Rivero AF, Pérez-Cejas A, Martín M, Gonzalez V, Pérez A, Rodin M, Jiménez A.
PMID: 34991877
Med Intensiva (Engl Ed). 2022 Jan;46(1):8-13. doi: 10.1016/j.medine.2020.06.015.

OBJECTIVE: No data are available on blood caspase-8 concentrations (the initiator caspase in the extrinsic apoptosis pathway) in septic patients. The present study thus describes the blood caspase-8 concentrations in survivors and non-survivors, and examines the possible association between...

Mortality of spontaneous intracerebral haemorrhage patients and high serum caspase-8 concentrations.

Anaesthesia, critical care & pain medicine

Lorente L, Martín MM, González-Rivero AF, Ramos-Gómez L, Sole-Violan J, Cáceres JJ, Villacampa-Jiménez JJ, Jiménez A, Pérez-Cejas A.
PMID: 34718185
Anaesth Crit Care Pain Med. 2021 Dec;40(6):100969. doi: 10.1016/j.accpm.2021.100969. Epub 2021 Oct 27.

PURPOSE: Apoptotic changes in brain samples have been found in haematoma areas of patients with spontaneous intracerebral haemorrhage (SIH) undergoing surgical haematoma evacuation. However, circulating caspase-8 concentrations in SIH patients have not been described. Thus, we carried out this...

Serum tissue inhibitor of MMP-1 levels at any moment of the first week of spontaneous intracerebral hemorrhage may predict early mortality.

Biomarkers in medicine

Lorente L, Martín MM, Pérez-Cejas A, González-Rivero AF, Sabatel R, Ramos-Gómez L, Argueso M, Solé-Violán J, Cáceres JJ, Jiménez A.
PMID: 34488441
Biomark Med. 2021 Oct;15(14):1245-1251. doi: 10.2217/bmm-2020-0859. Epub 2021 Sep 07.

No abstract available.

Showing 25 to 36 of 37 entries