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Showing 25 to 36 of 393 entries
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Proteome-Wide Analysis of Trypanosoma cruzi Exponential and Stationary Growth Phases Reveals a Subcellular Compartment-Specific Regulation.

Genes

Avila CC, Mule SN, Rosa-Fernandes L, Viner R, Barisón MJ, Costa-Martins AG, Oliveira GS, Teixeira MMG, Marinho CRF, Silber AM, Palmisano G.
PMID: 30111733
Genes (Basel). 2018 Aug 15;9(8). doi: 10.3390/genes9080413.

No abstract available.

A novel synthesis of N-hydroxy-3-aroylindoles and 3-aroylindoles.

Organic & biomolecular chemistry

Ieronimo G, Palmisano G, Maspero A, Marzorati A, Scapinello L, Masciocchi N, Cravotto G, Barge A, Simonetti M, Ameta KL, Nicholas KM, Penoni A.
PMID: 30065979
Org Biomol Chem. 2018 Oct 03;16(38):6853-6859. doi: 10.1039/c8ob01471j.

A straightforward indole synthesis via annulation of C-nitrosoaromatics with conjugated terminal alkynones was realised achieving a simple, highly regioselective, atom- and step economical access to 3-aroylindoles in moderate to good yields. Further functionalizations of indole scaffolds were investigated and...

The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells.

Human molecular genetics

Palmisano I, Bagnato P, Palmigiano A, Innamorati G, Rotondo G, Altimare D, Venturi C, Sviderskaya EV, Piccirillo R, Coppola M, Marigo V, Incerti B, Ballabio A, Surace EM, Tacchetti C, Bennett DC, Schiaffino MV.
PMID: 28854565
Hum Mol Genet. 2017 Aug 01;26(15):3028-3029. doi: 10.1093/hmg/ddx131.

No abstract available.

Modeling and simulation of the endogenous CYP3A induction marker 4β-hydroxycholesterol during enasidenib treatment.

Clinical pharmacology : advances and applications

Li Y, Connarn JN, Chen J, Tong Z, Palmisano M, Zhou S.
PMID: 30858735
Clin Pharmacol. 2019 Feb 15;11:39-50. doi: 10.2147/CPAA.S192687. eCollection 2019.

BACKGROUND: Enasidenib (IDHIFAMETHODS: Blood samples for PK and PD assessment were collected. A semi-mechanistic nonlinear mixed effect PK/PD model was successfully developed to characterize enasidenib plasma PK and to assess enasidenib-induced CYP3A activity.RESULTS: The PK model showed that enasidenib...

Distribution of pomalidomide into semen of healthy male subjects after multiple doses.

Clinical pharmacology : advances and applications

Li Y, Wang X, Liu L, Reyes J, Palmisano M, Zhou S.
PMID: 29765255
Clin Pharmacol. 2018 May 07;10:53-62. doi: 10.2147/CPAA.S167017. eCollection 2018.

OBJECTIVE: To assess whether pomalidomide can distribute into human semen and its duration in human semen.METHOD: A phase 1, randomized, double-blind, placebo-controlled study (CC-4047-CP-006) was conducted to evaluate the safety, tolerability, and pharmacokinetics of pomalidomide (CC-4047) following multiple daily...

Glans penis necrosis following paraphimosis: A rare case with brief literature review.

Urology case reports

Palmisano F, Gadda F, Spinelli MG, Montanari E.
PMID: 29181301
Urol Case Rep. 2017 Nov 13;16:57-58. doi: 10.1016/j.eucr.2017.09.016. eCollection 2018 Jan.

No abstract available.

Author Correction: Snake Venom Extracellular vesicles (SVEVs) reveal wide molecular and functional proteome diversity.

Scientific reports

Carregari VC, Rosa-Fernandes L, Baldasso P, Bydlowski SP, Marangoni S, Larsen MR, Palmisano G.
PMID: 30349050
Sci Rep. 2018 Oct 23;8(1):15908. doi: 10.1038/s41598-018-33284-3.

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.

A Phase 1, Open-Label Study in Healthy Subjects to Evaluate the Absolute Bioavailability of AG-221 by a Microtracer Approach.

Oncology and therapy

Wang X, Chen J, Reyes J, Zhou S, Palmisano M, Li Y.
PMID: 32700065
Oncol Ther. 2020 Jun;8(1):91-102. doi: 10.1007/s40487-019-0097-7. Epub 2019 Jul 19.

INTRODUCTION: The purpose of this study was to evaluate the absolute bioavailability (BA) of AG-221 following a single oral dose of 100 mg AG-221 and an intravenous (IV) dose of ~ 100 μg AG-221 containing approximately 300 nCi of...

Clinical factors affecting semen improvement after microsurgical subinguinal varicocelectomy: which subfertile patients benefit from surgery?.

Therapeutic advances in urology

Palmisano F, Moreno-Mendoza D, Ievoli R, Veber-Moisés-Da Silva G, Gasanz-Serrano C, Villegas-Osorio JF, Peraza-Godoy MF, Vives Á, Bassas L, Montanari E, Ruiz-Castañé E, Sarquella-Geli J, Sánchez-Curbelo J.
PMID: 31741684
Ther Adv Urol. 2019 Nov 08;11:1756287219887656. doi: 10.1177/1756287219887656. eCollection 2019.

BACKGROUND: The exact mechanism of varicocele-related infertility is still elusive, therefore, the current challenges for its management lie in determining which patients stand to benefit most from surgical correction. The authors aimed to assess the clinical factors affecting semen...

Endoscopic repair of a vesicouterine fistula with the injection of microfragmented autologous adipose tissue (Lipogems.

Turkish journal of urology

Spinelli MG, Lorusso V, Palmisano F, Morelli M, Dell'Orto PG, Tremolada C, Montanari E.
PMID: 32744991
Turk J Urol. 2020 Sep;46(5):398-402. doi: 10.5152/tud.2020.20170. Epub 2020 Jul 30.

Vesicouterine fistula (VUF) is a rare extra-anatomical communication developing between the uterus or cervix and the urinary bladder, most commonly after an iatrogenic injury during a cesarean section. Patients with VUF may have various clinical presentations, ranging from Youssef's...

Vection Is Enhanced by Increased Exposure to Optic Flow.

i-Perception

Seno T, Murata K, Fujii Y, Kanaya H, Ogawa M, Tokunaga K, Palmisano S.
PMID: 30046430
Iperception. 2018 May 23;9(3):2041669518774069. doi: 10.1177/2041669518774069. eCollection 2018.

We examined whether vection strength could be modulated by altering the exposure duration to optic flow. Experiment 1 sourced 150 different video clips from various Japanese animation works which simulated self-motion. Despite large differences in the content of these...

A Phase I, open-label, randomized, crossover study in healthy subjects to evaluate the bioavailability of, and the food effect on, a pomalidomide oral liquid suspension.

Clinical pharmacology : advances and applications

Li Y, Liu L, Huang L, Wang X, Hoffmann M, Reyes J, Palmisano M, Zhou S.
PMID: 30050331
Clin Pharmacol. 2018 Jul 19;10:89-99. doi: 10.2147/CPAA.S171735. eCollection 2018.

OBJECTIVE: The aim of this study was to evaluate the bioavailability of a pomalidomide oral liquid suspension relative to the commercial capsule formulation and to assess the food effect on the pomalidomide oral liquid suspension when administered as a...

Showing 25 to 36 of 393 entries