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Showing 9985 to 9996 of 13133 entries
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A Modified Nucleoside 6-Thio-2'-Deoxyguanosine Exhibits Antitumor Activity in Gliomas.

Clinical cancer research : an official journal of the American Association for Cancer Research

Yu S, Wei S, Savani M, Lin X, Du K, Mender I, Siteni S, Vasilopoulos T, Reitman ZJ, Ku Y, Wu D, Liu H, Tian M, Chen Y, Labrie M, Charbonneau CM, Sugarman E, Bowie M, Hariharan S, Waitkus M, Jiang W, McLendon RE, Pan E, Khasraw M, Walsh KM, Lu Y, Herlyn M, Mills G, Herbig U, Wei Z, Keir ST, Flaherty K, Liu L, Wu K, Shay JW, Abdullah K, Zhang G, Ashley DM.
PMID: 34593527
Clin Cancer Res. 2021 Dec 15;27(24):6800-6814. doi: 10.1158/1078-0432.CCR-21-0374. Epub 2021 Sep 30.

PURPOSE: To investigate the therapeutic role of a novel telomere-directed inhibitor, 6-thio-2'-deoxyguanosine (THIO) in gliomas both EXPERIMENTAL DESIGN: A panel of human and mouse glioma cell lines was used to test therapeutic efficacy of THIO using cell viability assays,...

One-pot construction of nitrogen-rich polymeric ionic porous networks for effective CO.

Polymer chemistry

Ai C, Ke X, Tang J, Tang X, Abu-Reziq R, Chang J, Yuan J, Yu G, Pan C.
PMID: 35027946
Polym Chem. 2021 Nov 24;13(1):121-129. doi: 10.1039/d1py01121a. eCollection 2021 Dec 21.

Facile preparation of ionic porous networks (IPNs) with large and permanent porosity is highly desirable for CO

Shared Molecular Mechanisms between Atherosclerosis and Periodontitis by Analyzing the Transcriptomic Alterations of Peripheral Blood Monocytes.

Computational and mathematical methods in medicine

Ning W, Ma Y, Li S, Wang X, Pan H, Wei C, Zhang S, Bai D, Liu X, Deng Y, Acharya A, Pelekos G, Savkovic V, Li H, Gaus S, Haak R, Schmalz G, Ziebolz D, Ma Y, Xu Y.
PMID: 34899963
Comput Math Methods Med. 2021 Dec 03;2021:1498431. doi: 10.1155/2021/1498431. eCollection 2021.

OBJECTIVE: This study investigated the nature of shared transcriptomic alterations in PBMs from periodontitis and atherosclerosis to unravel molecular mechanisms underpinning their association.METHODS: Gene expression data from PBMs from patients with periodontitis and those with atherosclerosis were each downloaded...

The early phase of the COVID-19 epidemic in Lombardy, Italy.

Epidemics

Cereda D, Manica M, Tirani M, Rovida F, Demicheli V, Ajelli M, Poletti P, Trentini F, Guzzetta G, Marziano V, Piccarreta R, Barone A, Magoni M, Deandrea S, Diurno G, Lombardo M, Faccini M, Pan A, Bruno R, Pariani E, Grasselli G, Piatti A, Gramegna M, Baldanti F, Melegaro A, Merler S.
PMID: 34814093
Epidemics. 2021 Nov 20;37:100528. doi: 10.1016/j.epidem.2021.100528. Epub 2021 Nov 20.

BACKGROUND: In the night of February 20, 2020, the first epidemic of the novel coronavirus disease (COVID-19) outside Asia was uncovered by the identification of its first patient in Lombardy region, Italy. In the following weeks, Lombardy experienced a...

Coordination of EZH2 and SOX2 specifies human neural fate decision.

Cell regeneration (London, England)

Zhao Y, Wang T, Zhang Y, Shi L, Zhang C, Zhang J, Yao J, Chen Q, Zhong X, Wei Y, Shan Y, Pan G.
PMID: 34487238
Cell Regen. 2021 Sep 06;10(1):30. doi: 10.1186/s13619-021-00092-6.

Polycomb repressive complexes (PRCs) are essential in mouse gastrulation and specify neural ectoderm in human embryonic stem cells (hESCs), but the underlying molecular basis remains unclear. Here in this study, by employing an array of different approaches, such as...

Submicron Metal 3D Printing by Ultrafast Laser Heating and Induced Ligand Transformation of Nanocrystals.

ACS applied materials & interfaces

Podder C, Gong X, Yu X, Shou W, Pan H.
PMID: 34432433
ACS Appl Mater Interfaces. 2021 Sep 08;13(35):42154-42163. doi: 10.1021/acsami.1c10775. Epub 2021 Aug 25.

Currently, light-based three-dimensional (3D) printing with submicron features is mainly developed based on photosensitive polymers or inorganic-polymer composite materials. To eliminate polymer/organic additives, a strategy for direct 3D assembly and printing of metallic nanocrystals without additives is presented. Ultrafast...

Maternal air pollution exposure and neonatal congenital heart disease: A multi-city cross-sectional study in eastern China.

International journal of hygiene and environmental health

Li D, Xu W, Qiu Y, Pan F, Lou H, Li J, Jin Y, Wu T, Pan L, An J, Xu J, Cheng W, Tao L, Lei Y, Huang C, Yin F, Shu Q.
PMID: 34875582
Int J Hyg Environ Health. 2021 Dec 04;240:113898. doi: 10.1016/j.ijheh.2021.113898. Epub 2021 Dec 04.

OBJECTIVE: To examine the association between air pollution and neonatal congenital heart disease (CHD), and evaluate the cumulative burden of CHD attributed to above certain level for ambient air pollution exposure.METHODS: We identified newborns who were diagnosed as CHD...

High risk factors for severe hand, foot and mouth disease: a multicenter retrospective survey in Anhui Province China, 2008-2009.

Indian journal of dermatology

Pan J, Chen M, Zhang X, Chen Y, Liu H, Shen W.
PMID: 22837575
Indian J Dermatol. 2012 Jul;57(4):316-21. doi: 10.4103/0019-5154.97683.

OBJECTIVES: This study sought to determine the high risk factors for severe hand, foot, and mouth disease (HFMD).MATERIALS AND METHODS: Retrospective 229 severe HFMD cases from four hospitals in FuYang, HeFei, and BoZhou (Anhui Provincial Hospital, Fuyang City People's...

Bioactive materials

Liang T, Zeng L, Shi Y, Pan H, Chu PK, Yeung KWK, Zhao Y.
PMID: 33778187
Bioact Mater. 2021 Mar 09;6(10):3049-3061. doi: 10.1016/j.bioactmat.2021.02.025. eCollection 2021 Oct.

The effects of dual Zr and O plasma immersion ion implantation (Zr & O PIII) on antibacterial properties of ZK60 Mg alloys are systematically investigated. The results show that a hydrophobic, smooth, and ZrO

The Richness and Diversity of Catalases in Bacteria.

Frontiers in microbiology

Yuan F, Yin S, Xu Y, Xiang L, Wang H, Li Z, Fan K, Pan G.
PMID: 33815333
Front Microbiol. 2021 Mar 19;12:645477. doi: 10.3389/fmicb.2021.645477. eCollection 2021.

Catalases play a key role in the defense against oxidative stress in bacteria by catalyzing the decomposition of H

To Find Out the Relationship Between Levels of Glycosylated Hemoglobin with Meibomian Gland Dysfunction in Patients with Type 2 Diabetes.

Therapeutics and clinical risk management

Fan F, Li X, Li K, Jia Z.
PMID: 34393486
Ther Clin Risk Manag. 2021 Aug 06;17:797-807. doi: 10.2147/TCRM.S324423. eCollection 2021.

AIM: The aim of this study was to investigate the relationship between levels of glycosylated hemoglobin (HbA1c) with meibomian gland dysfunction (MGD) in patients with type 2 diabetes mellitus (T2DM) and to further explore the related influencing factors.METHODS: Totally,...

Circular RNA FLNA acts as a sponge of miR-486-3p in promoting lung cancer progression via regulating XRCC1 and CYP1A1.

Cancer gene therapy

Pan J, Huang G, Yin Z, Cai X, Gong E, Li Y, Xu C, Ye Z, Cao Z, Cheng W.
PMID: 33500536
Cancer Gene Ther. 2022 Jan;29(1):101-121. doi: 10.1038/s41417-021-00293-w. Epub 2021 Jan 26.

Significantly high-expressed circFLNA has been found in various cancer cell lines, but not in lung cancer. Therefore, this study aimed to explore the role of circFLNA in the progression of lung cancer. The target gene of circFLNA was determined...

Showing 9985 to 9996 of 13133 entries