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1-[3-(2-Benz-yloxy-6-hy-droxy-4-methyl-phen-yl)-5-[3,5-bis-(tri-fluoro-meth-yl)phen-yl]-4,5-di-hydro-1H-pyrazol-1-yl]propane-1-one.

Acta crystallographica. Section E, Structure reports online

Patel UH, Gandhi SA, Barot VM, Varma NV.
PMID: 23795028
Acta Crystallogr Sect E Struct Rep Online. 2013 May 04;69:o840. doi: 10.1107/S160053681301180X. Print 2013 Jun 01.

In the title compound, C28H24F6N2O3, the mean plane of the central pyrazoline ring forms dihedral angles of 2.08 (9) and 69.02 (16)° with the 2-benz-yloxy-6-hy-droxy-4-methyl-phenyl and 3,5-bis-(tri-fluoro-meth-yl)phenyl rings, respectively. The dihedral angle between the mean planes of the pyrazoline...

In vitro degradation and cell attachment studies of a new electrospun polymeric tubular graft.

Progress in biomaterials

Patel HN, Thai KN, Chowdhury S, Singh R, Vohra YK, Thomas V.
PMID: 26566465
Prog Biomater. 2015;4(2):67-76. doi: 10.1007/s40204-015-0038-y. Epub 2015 Apr 09.

Electrospinning technique was utilized to engineer a small-diameter (id = 4 mm) tubular graft. The tubular graft was made from biocompatible and biodegradable polymers polycaprolactone (PCL) and poliglecaprone with 3:1 (PCL:PGC) ratio. Enzymatic degradation effect on the mechanical properties...

The Effect of Primer on Bond Strength of Silicone Prosthetic Elastomer to Polymethylmethacrylate: An in vitro Study.

Journal of clinical and diagnostic research : JCDR

Patel H, C M RK, A A P, Bithu AS, Shah K, Prajapati S.
PMID: 25954703
J Clin Diagn Res. 2015 Mar;9(3):ZC38-42. doi: 10.7860/JCDR/2015/11217.5704. Epub 2015 Mar 01.

INTRODUCTION: The aim of the study is to evaluate interfacial bond strength between silicone prosthetic elastomers and polymethylmethacrylate (PMMA).MATERIALS AND METHODS: Silicone elastomers were attached to PMMA and a total 120 specimens were fabricated which were then subdivided into...

What is a segment?.

EvoDevo

Hannibal RL, Patel NH.
PMID: 24345042
Evodevo. 2013 Dec 17;4(1):35. doi: 10.1186/2041-9139-4-35.

Animals have been described as segmented for more than 2,000 years, yet a precise definition of segmentation remains elusive. Here we give the history of the definition of segmentation, followed by a discussion on current controversies in defining a...

Increased expression of H19/miR-675 is associated with a low fat-free mass index in patients with COPD.

Journal of cachexia, sarcopenia and muscle

Lewis A, Lee JY, Donaldson AV, Natanek SA, Vaidyanathan S, Man WD, Hopkinson NS, Sayer AA, Patel HP, Cooper C, Syddall H, Polkey MI, Kemp PR.
PMID: 27239417
J Cachexia Sarcopenia Muscle. 2016 Jun;7(3):330-44. doi: 10.1002/jcsm.12078. Epub 2016 Jan 05.

BACKGROUND: Loss of muscle mass and strength is a significant comorbidity in patients with chronic obstructive pulmonary disease (COPD) that limits their quality of life and has prognostic implications but does not affect everyone equally. To identify mechanisms that...

Gene therapy for GM1 gangliosidosis: challenges of translational medicine.

Annals of translational medicine

Hayward C, Patel HC, Manohar SG, Lyon AR.
PMID: 26046074
Ann Transl Med. 2015 May;3:S28. doi: 10.3978/j.issn.2305-5839.2015.02.28.

No abstract available.

Ascorbic acid does not enhance hypoxia-induced vasodilation in healthy older men.

Physiological reports

Pollock JP, Patel HM, Randolph BJ, Heffernan MJ, Leuenberger UA, Muller MD.
PMID: 25052494
Physiol Rep. 2014 Jul 22;2(7). doi: 10.14814/phy2.12091. Print 2014 Jul 01.

In response to hypoxia, a net vasodilation occurs in the limb vasculature in young healthy humans and this is referred to as "hypoxia-induced vasodilation". We performed two separate experiments to determine (1) if hypoxia-induced forearm vasodilation is impaired in...

Serotonin reuptake inhibitors and post-gastrostomy bleeding: reevaluating the link.

Therapeutics and clinical risk management

Patel H, Gaduputi V, Sakam S, Kumar K, Chime C, Balar B.
PMID: 26346885
Ther Clin Risk Manag. 2015 Aug 27;11:1283-9. doi: 10.2147/TCRM.S87044. eCollection 2015.

INTRODUCTION: Serotonin reuptake inhibitors (SRIs) are one of the most commonly prescribed classes of medications with a relatively safe side-effect profile. However, SRIs are being increasingly reported to be associated with bleeding complications in patients undergoing invasive procedures resulting...

Enhancing Intracranial Delivery of Clinically Relevant Non-viral Gene Vectors.

RSC advances

Berry S, Mastorakos P, Zhang C, Song E, Patel H, Suk JS, Hanes J.
PMID: 27642512
RSC Adv. 2016;48(6):41665-41674. doi: 10.1039/C6RA01546H. Epub 2016 Apr 19.

Gene therapy is a promising strategy for the management of various neurological disorders that do not respond adequately to conventional therapeutics. The development of gene vectors with favorable safety profiles that can achieve uniform distribution and high-level transgene expression...

Genotyping of major histocompatibility complex Class II DRB gene in Rohilkhandi goats by polymerase chain reaction-restriction fragment length polymorphism and DNA sequencing.

Veterinary world

Shrivastava K, Kumar P, Sahoo NR, Kumar A, Khan MF, Kumar A, Prasad A, Patel BH, Nasir A, Bhushan B, Sharma D.
PMID: 27047015
Vet World. 2015 Oct;8(10):1183-8. doi: 10.14202/vetworld.2015.1183-1188. Epub 2015 Oct 09.

AIM: To study the major histocompatibility complex (MHC) Class II DRB1 gene polymorphism in Rohilkhandi goat using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and nucleotide sequencing techniques.MATERIALS AND METHODS: DNA was isolated from 127 Rohilkhandi goats maintained at...

Effect of drinking water temperature on physiological variables of crossbred dairy cattle at high altitude temperate region of Himalayas.

Veterinary world

Golher DM, Thirumurugan P, Patel BH, Upadhyay VK, Sahu S, Gaur GK, Bhoite SH.
PMID: 27047019
Vet World. 2015 Oct;8(10):1210-4. doi: 10.14202/vetworld.2015.1210-1214. Epub 2015 Oct 17.

AIM: The objective of study was to investigate the effects of drinking water on certain physiological parameters such as heart rate (HR), respiration rate (RR), rectal temperature (RT) and, ruminal motility (RM).MATERIALS AND METHODS: The experiment was carried out...

Geriatric Respondents and Non-Respondents to Probiotic Intervention Can be Differentiated by Inherent Gut Microbiome Composition.

Frontiers in microbiology

Senan S, Prajapati JB, Joshi CG, Sreeja V, Gohel MK, Trivedi S, Patel RM, Pandya H, Singh US, Phatak A, Patel HA.
PMID: 26441879
Front Microbiol. 2015 Sep 08;6:944. doi: 10.3389/fmicb.2015.00944. eCollection 2015.

SCOPE: Probiotic interventions are known to have been shown to influence the composition of the intestinal microbiota in geriatrics. The growing concern is the apparent variation in response to identical strain dosage among human volunteers. One factor that governs...

Showing 13 to 24 of 1374 entries