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Showing 25 to 36 of 285 entries
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Fetal cardiac function by mitral and tricuspid annular plane systolic excursion using spatio-temporal image correlation M-mode and left cardiac output in fetuses of pregestational diabetic mothers.

Obstetrics & gynecology science

Bravo-Valenzuela NJM, Peixoto AB, Mattar R, Araujo Júnior E.
PMID: 33499582
Obstet Gynecol Sci. 2021 May;64(3):257-265. doi: 10.5468/ogs.20274. Epub 2021 Jan 27.

OBJECTIVE: To assess the mitral and tricuspid annular plane systolic excursions (MAPSE and TAPSE, respectively) and cardiac output (CO) in fetuses of pregnant women with pregestational diabetes mellitus (DM) using spatio-temporal image correlation M-mode (STIC-M) and virtual organ computer-aided...

Metformin and fluoxetine improve depressive-like behavior in a murine model of Parkinsońs disease through the modulation of neuroinflammation, neurogenesis and neuroplasticity.

International immunopharmacology

Mendonça IP, Paiva IHR, Duarte-Silva EP, Melo MG, Silva RSD, Oliveira WH, Costa BLDSAD, Peixoto CA.
PMID: 34890997
Int Immunopharmacol. 2021 Dec 07;102:108415. doi: 10.1016/j.intimp.2021.108415. Epub 2021 Dec 07.

Thereabout 30-40% of patients with Parkinson's Disease (PD) also have depression contributing to the loss of quality of life. Among the patients who treat depression, about 50% do not show significant improvement due to the limited efficacy of the...

Bacillary prostatitis after intravesical immunotherapy: a rare adverse effect.

Case reports in oncology

Joaquim A, Custódio S, Pimentel FL, Matos JF, Peixoto V, Faria AL, Macedo JE, Macias E, Rego S, Araújo A.
PMID: 22539919
Case Rep Oncol. 2012 Jan;5(1):80-3. doi: 10.1159/000336445. Epub 2012 Feb 04.

Nowadays, the most efficient form of intravesical immunotherapy for superficial transitional cell carcinoma of the urinary bladder is the instillation of bacillus Calmette-Guérin (BCG), proceeding from an attenuated strain of Mycobacterium bovis. In up to 40% of cases, its...

Effect of grade 3 placenta < 36 weeks of pregnancy on perinatal outcomes.

Minerva obstetrics and gynecology

Carneiro MB, Araujo AF, Silva LD, Petrini CG, Reis LM, Araujo Júnior E, Peixoto AB.
PMID: 34825789
Minerva Obstet Gynecol. 2021 Nov 26; doi: 10.23736/S2724-606X.21.04963-0. Epub 2021 Nov 26.

BACKGROUND: To assess whether the presence of grade 3 placenta

Anti-inflammatory activity of novel thiosemicarbazone compounds indole-based as COX inhibitors.

Pharmacological reports : PR

Jacob ÍTT, Gomes FOS, de Miranda MDS, de Almeida SMV, da Cruz-Filho IJ, Peixoto CA, da Silva TG, Moreira DRM, de Melo CML, de Oliveira JF, de Lima MCA.
PMID: 33590474
Pharmacol Rep. 2021 Jun;73(3):907-925. doi: 10.1007/s43440-021-00221-7. Epub 2021 Feb 15.

BACKGROUND: In this article, a series of 20 new thiosemicarbazone derivatives containing indole were synthesized and evaluated for their anti-inflammatory potential.METHODS: The compounds were obtained through a synthetic route of only two steps, with yields that varied between 33.6...

[Impact of Confinement on the Health of Children and Adolescents During the COVID-19 Pandemic].

Acta medica portuguesa

Peixoto D, Leal B, Ribeiro D, Correia L, Hipólito E, Rocha P.
PMID: 33661728
Acta Med Port. 2021 Mar 04; doi: 10.20344/amp.15885. Epub 2021 Mar 04.

No abstract available.

SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer.

Cancer research

Martinez RS, Salji MJ, Rushworth L, Ntala C, Rodriguez Blanco G, Hedley A, Clark W, Peixoto P, Hervouet E, Renaude E, Kung SHY, Galbraith LCA, Nixon C, Lilla S, MacKay GM, Fazli L, Gaughan L, Sumpton D, Gleave ME, Zanivan S, Blomme A, Leung HY.
PMID: 33985973
Cancer Res. 2021 Jul 01;81(13):3664-3678. doi: 10.1158/0008-5472.CAN-20-3694. Epub 2021 May 13.

Androgen deprivation therapy (ADT) is the standard of care for treatment of nonresectable prostate cancer. Despite high treatment efficiency, most patients ultimately develop lethal castration-resistant prostate cancer (CRPC). In this study, we performed a comparative proteomic analysis of three

Decoding and perturbing decision states in real time.

Nature

Peixoto D, Verhein JR, Kiani R, Kao JC, Nuyujukian P, Chandrasekaran C, Brown J, Fong S, Ryu SI, Shenoy KV, Newsome WT.
PMID: 33473215
Nature. 2021 Mar;591(7851):604-609. doi: 10.1038/s41586-020-03181-9. Epub 2021 Jan 20.

In dynamic environments, subjects often integrate multiple samples of a signal and combine them to reach a categorical judgment

References Values of Fetal Heart Myocardial Volume by Three-Dimensional Ultrasound using Spatiotemporal Image Correlation and Virtual Organ Computer-Aided Analysis Methods and Their Applicability in Pregestational Diabetic Women.

American journal of perinatology

Melo Júnior JF, Bravo-Valenzuela NJ, Nardozza LMM, Peixoto AB, Mattar R, Martins WP, Pares DBDS, Araujo Júnior E.
PMID: 31858500
Am J Perinatol. 2021 Jun;38(7):721-727. doi: 10.1055/s-0039-3400983. Epub 2019 Dec 13.

OBJECTIVE: To determine reference values for myocardial volume of the fetal heart using three-dimensional ultrasound with spatiotemporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL) and to assess their applicability in women with pregestational diabetes.STUDY DESIGN: This retrospective...

Metformin and fluoxetine improve depressive-like behavior in a murine model of Parkinsońs disease through the modulation of neuroinflammation, neurogenesis and neuroplasticity.

International immunopharmacology

Mendonça IP, Paiva IHR, Duarte-Silva EP, Melo MG, Silva RSD, Oliveira WH, Costa BLDSAD, Peixoto CA.
PMID: 34890997
Int Immunopharmacol. 2021 Dec 08;102:108415. doi: 10.1016/j.intimp.2021.108415. Epub 2021 Dec 08.

Thereabout 30-40% of patients with Parkinson's Disease (PD) also have depression contributing to the loss of quality of life. Among the patients who treat depression, about 50% do not show significant improvement due to the limited efficacy of the...

Prenatal diagnosis of congenitally corrected transposition of the great arteries.

Journal of ultrasonography

Bravo-Valenzuela NJ, Peixoto AB, Araujo Júnior E.
PMID: 32021715
J Ultrason. 2019 Dec;19(79):314-317. doi: 10.15557/JoU.2019.0048. Epub 2019 Dec 31.

Congenitally corrected transposition of the great arteries is a rare and complex congenital heart disease. It essentially occurs with atrioventricular and ventriculoarterial discordance, in which the great vessels become parallel. Cases of corrected transposition of the great arteries are...

Doxycycline reverses cognitive impairment, neuroinflammation and oxidative imbalance induced by D-amphetamine mania model in mice: A promising drug repurposing for bipolar disorder treatment?.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology

Chaves Filho AJM, Cunha NL, Rodrigues PA, de Souza AG, Soares MV, Jucá PM, de Queiroz T, Clemente DCDS, Mottin M, Andrade CH, Peixoto CA, Macedo DS.
PMID: 33191076
Eur Neuropsychopharmacol. 2021 Jan;42:57-74. doi: 10.1016/j.euroneuro.2020.11.007. Epub 2020 Nov 12.

Immune-inflammatory mechanisms are involved in the pathophysiology of bipolar disorder. Tetracyclines present neuroprotective actions based on their anti-inflammatory and microglia suppressant effects. Doxycycline (DOXY) is a tetracycline that demonstrates a better usage profile with protective actions against inflammation and...

Showing 25 to 36 of 285 entries