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Showing 241 to 252 of 252 entries
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Annales de cardiologie et d'angeiologie

Amara W, Reynaud N, Auquier N, Jourda F, Milhem A, Socié P, Pfeffer A, Mlayeh D, Bader H, Taieb J.
PMID: 34635329
Ann Cardiol Angeiol (Paris). 2021 Nov;70(5):351-354. doi: 10.1016/j.ancard.2021.09.001. Epub 2021 Oct 09.

No abstract available.

Mode of Death in Patients With Heart Failure and Preserved Ejection Fraction: Insights From PARAGON-HF Trial.

Circulation. Heart failure

Desai AS, Vaduganathan M, Cleland JG, Claggett BL, Barkoudah E, Finn P, McCausland FR, Yilmaz MB, Lefkowitz M, Shi V, Pfeffer MA, McMurray JJV, Solomon SD.
PMID: 34807713
Circ Heart Fail. 2021 Nov 22;CIRCHEARTFAILURE121008597. doi: 10.1161/CIRCHEARTFAILURE.121.008597. Epub 2021 Nov 22.

BACKGROUND: Patients with heart failure (HF) and preserved left ventricular ejection fraction comprise a heterogeneous group including some with mildly reduced EF. We hypothesized that mode of death differs by EF in ambulatory patients with HF and preserved left...

Novel structural-related analogs of PFI-3 (SRAPs) that target the BRG1 catalytic subunit of the SWI/SNF complex increase the activity of temozolomide in glioblastoma cells.

Bioorganic & medicinal chemistry

He Y, Yang C, Wang Y, Sacher JR, Sims MM, Pfeffer LM, Miller DD.
PMID: 34863065
Bioorg Med Chem. 2022 Jan 01;53:116533. doi: 10.1016/j.bmc.2021.116533. Epub 2021 Nov 27.

Glioblastoma (GBM) is the most aggressive and treatment-refractory malignant adult brain cancer. After standard of care therapy, the overall median survival for GBM is only ∼6 months with a 5-year survival

Growth differentiation factor 15 predicts poor prognosis in patients with heart failure and reduced ejection fraction and anemia: results from RED-HF.

Clinical research in cardiology : official journal of the German Cardiac Society

Ueland T, Gullestad L, Kou L, Young JB, Pfeffer MA, van Veldhuisen DJ, Swedberg K, Mcmurray JJV, Desai AS, Anand IS, Aukrust P.
PMID: 34611778
Clin Res Cardiol. 2021 Oct 05; doi: 10.1007/s00392-021-01944-6. Epub 2021 Oct 05.

AIMS: We aimed to assess the value of GDF-15, a stress-responsive cytokine, in predicting clinical outcomes in patients with heart failure (HF) with reduced ejection fraction (HFrEF) and anemia METHODS AND RESULTS: Serum GDF-15 was assessed in 1582 HFrEF...

Influence of study discontinuation during the run-in period on the estimated efficacy of sacubitril/valsartan in the PARAGON-HF trial.

European journal of heart failure

Suzuki K, Claggett B, Minamisawa M, Packer M, Zile MR, Pfeffer MA, Chiang LM, Lefkowitz M, McMurray JJV, Solomon SD, Desai AS.
PMID: 34114720
Eur J Heart Fail. 2021 Jun 11; doi: 10.1002/ejhf.2262. Epub 2021 Jun 11.

AIMS: The 4822 patients randomized in the PARAGON-HF trial were a subset of 5746 initially eligible patients who entered sequential run-in periods. We identified patient factors associated with study discontinuation during the run-in period and estimated the implications of...

Frontiers in veterinary science

Obiegala A, Pfeffer M, Kiefer D, Kiefer M, Król N, Silaghi C.
PMID: 33537358
Front Vet Sci. 2021 Jan 18;7:625641. doi: 10.3389/fvets.2020.625641. eCollection 2020.

Most

Direct Observation of Amide Bond Formation in a Plasmonic Nanocavity Triggered by Single Nanoparticle Collisions.

Journal of the American Chemical Society

Kong N, Guo J, Chang S, Pan J, Wang J, Zhou J, Liu J, Zhou H, Pfeffer FM, Liu J, Barrow CJ, He J, Yang W.
PMID: 34164979
J Am Chem Soc. 2021 Jul 07;143(26):9781-9790. doi: 10.1021/jacs.1c02426. Epub 2021 Jun 24.

The real-time observation of chemical bond formation at the single-molecule level is one of the great challenges in the fields of organic and biomolecular chemistry. Valuable information can be gleaned that is not accessible using ensemble-average measurements. Although remarkably...

Diabetes and pre-diabetes in patients with heart failure and preserved ejection fraction.

European journal of heart failure

Jackson AM, Rørth R, Liu J, Kristensen SL, Anand IS, Claggett BL, Cleland JGF, Chopra VK, Desai AS, Ge J, Gong J, Lam CSP, Lefkowitz MP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rizkala AR, Rouleau JL, Seferović PM, Tromp J, Van Veldhuisen DJ, Yilmaz MB, Zannad F, Zile MR, Køber L, Petrie MC, Jhund PS, Solomon SD, McMurray JJV.
PMID: 34918855
Eur J Heart Fail. 2021 Dec 17; doi: 10.1002/ejhf.2403. Epub 2021 Dec 17.

AIM: There is an association between heart failure with preserved ejection fraction (HFpEF) and insulin resistance, but less is known about the diabetic continuum, and in particular about pre-diabetes, in HFpEF. We examined characteristics and outcomes of participants with...

Three-dimensional deformation measured in an alaskan glacier .

Science (New York, N.Y.)

Harper JT, Humphrey NF, Pfeffer WT.
PMID: 9721096
Science. 1998 Aug 28;281(5381):1340-2. doi: 10.1126/science.281.5381.1340.

Measurements of movement along 28 boreholes reveal the three-dimensional flow field in a 6 million cubic meter reach of Worthington Glacier, a temperate valley glacier located in Alaska. Sliding at the bed accounted for 60 to 70 percent of...

Impact of Chronic Obstructive Pulmonary Disease in Patients With Heart Failure With Preserved Ejection Fraction: Insights From PARAGON-HF.

Journal of the American Heart Association

Mooney L, Hawkins NM, Jhund PS, Redfield MM, Vaduganathan M, Desai AS, Rouleau JL, Minamisawa M, Shah AM, Lefkowitz MP, Zile MR, Van Veldhuisen DJ, Pfeffer MA, Anand IS, Maggioni AP, Senni M, Claggett BL, Solomon SD, McMurray JJV.
PMID: 34796742
J Am Heart Assoc. 2021 Dec 07;10(23):e021494. doi: 10.1161/JAHA.121.021494. Epub 2021 Nov 19.

Background Little is known about the impact of chronic obstructive pulmonary disease (COPD) in patients with heart failure with preserved ejection fraction (HFpEF). Methods and Results We examined outcomes in patients with heart failure with preserved ejection fraction, according...

Men, trans/masculine, and non-binary people negotiating conception: Normative resistance and inventive pragmatism.

International journal of transgender health

Riggs DW, Pfeffer CA, Pearce R, Hines S, White FR.
PMID: 34476419
Int J Transgend Health. 2021 Sep 01;22(1):6-17. doi: 10.1080/15532739.2020.1808554. eCollection 2021.

BACKGROUND: Growing numbers of men, trans/masculine, and non-binary people are undertaking pregnancies, yet relatively little is known about the experiences of this diverse population in regard to conception.AIMS: This study sought to examine men's, trans/masculine, and non-binary people's experiences...

The Society of Astrologers (.

British journal for the history of science

Pfeffer M.
PMID: 33719982
Br J Hist Sci. 2021 Jun;54(2):133-153. doi: 10.1017/S0007087421000029.

Before the Royal Society there was the Society of Astrologers (c.1647-1684), a group of around forty practitioners who met in London to enjoy lavish feasts, listen to sermons and exchange instruments and manuscripts. This article, drawing on untapped archival...

Showing 241 to 252 of 252 entries