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Single-dose replicating poxvirus vector-basedRBD vaccine drives robust humoral and T cellimmune response against SARS-CoV-2 infection.

Molecular therapy : the journal of the American Society of Gene Therapy

Boulton S, Poutou J, Martin NT, Azad T, Singaravelu R, Crupi MJF, Jamieson T, He X, Marius R, Petryk J, Tanese de Souza C, Austin B, Taha Z, Whelan J, Khan ST, Pelin A, Rezaei R, Surendran A, Tucker S, Brown EEF, Dave J, Diallo JS, Auer R, Angel JB, Cameron DW, Cailhier JF, Lapointe R, Potts K, Mahoney DJ, Bell JC, Ilkow CS.
PMID: 34687845
Mol Ther. 2021 Oct 20; doi: 10.1016/j.ymthe.2021.10.008. Epub 2021 Oct 20.

The coronavirus disease 2019 (COVID-19) pandemic requires the continued development of safe, long-lasting, and efficacious vaccines for preventive responses to major outbreaks around the world, and especially in isolated and developing countries. To combat severe acute respiratory syndrome coronavirus...

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Boulton S, Poutou J, Martin NT, et al. Single-dose replicating poxvirus vector-basedRBD vaccine drives robust humoral and T cellimmune response against SARS-CoV-2 infection. Mol Ther. 2021;doi: 10.1016/j.ymthe.2021.10.008.
Boulton, S., Poutou, J., Martin, N. T., Azad, T., Singaravelu, R., Crupi, M. J. F., Jamieson, T., He, X., Marius, R., Petryk, J., Tanese de Souza, C., Austin, B., Taha, Z., Whelan, J., Khan, S. T., Pelin, A., Rezaei, R., Surendran, A., Tucker, S., Brown, E. E. F., Dave, J., Diallo, J. S., Auer, R., Angel, J. B., Cameron, D. W., Cailhier, J. F., Lapointe, R., Potts, K., Mahoney, D. J., Bell, J. C., & Ilkow, C. S. (2021). Single-dose replicating poxvirus vector-basedRBD vaccine drives robust humoral and T cellimmune response against SARS-CoV-2 infection. Molecular therapy : the journal of the American Society of Gene Therapy, . https://doi.org/10.1016/j.ymthe.2021.10.008
Boulton, Stephen, et al. "Single-dose replicating poxvirus vector-basedRBD vaccine drives robust humoral and T cellimmune response against SARS-CoV-2 infection." Molecular therapy : the journal of the American Society of Gene Therapy vol. (2021). doi: https://doi.org/10.1016/j.ymthe.2021.10.008
Boulton S, Poutou J, Martin NT, Azad T, Singaravelu R, Crupi MJF, Jamieson T, He X, Marius R, Petryk J, Tanese de Souza C, Austin B, Taha Z, Whelan J, Khan ST, Pelin A, Rezaei R, Surendran A, Tucker S, Brown EEF, Dave J, Diallo JS, Auer R, Angel JB, Cameron DW, Cailhier JF, Lapointe R, Potts K, Mahoney DJ, Bell JC, Ilkow CS. Single-dose replicating poxvirus vector-basedRBD vaccine drives robust humoral and T cellimmune response against SARS-CoV-2 infection. Mol Ther. 2021 Oct 20; doi: 10.1016/j.ymthe.2021.10.008. Epub 2021 Oct 20. PMID: 34687845; PMCID: PMC8527104.
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Hydro-climatic changes of wetlandscapes across the world.

Scientific reports

Åhlén I, Vigouroux G, Destouni G, Pietroń J, Ghajarnia N, Anaya J, Blanco J, Borja S, Chalov S, Chun KP, Clerici N, Desormeaux A, Girard P, Gorelits O, Hansen A, Jaramillo F, Kalantari Z, Labbaci A, Licero-Villanueva L, Livsey J, Maneas G, Pisarello KLM, Pahani DM, Palomino-Ángel S, Price R, Ricaurte-Villota C, Fernanda Ricaurte L, Rivera-Monroy VH, Rodriguez A, Rodriguez E, Salgado J, Sannel B, Seifollahi-Aghmiuni S, Simard M, Sjöberg Y, Terskii P, Thorslund J, Zamora DA, Jarsjö J.
PMID: 33531523
Sci Rep. 2021 Feb 02;11(1):2754. doi: 10.1038/s41598-021-81137-3.

Assessments of ecosystem service and function losses of wetlandscapes (i.e., wetlands and their hydrological catchments) suffer from knowledge gaps regarding impacts of ongoing hydro-climatic change. This study investigates hydro-climatic changes during 1976-2015 in 25 wetlandscapes distributed across the world's...

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Åhlén I, Vigouroux G, Destouni G, et al. Hydro-climatic changes of wetlandscapes across the world. Sci Rep. 2021;11(1):2754doi: 10.1038/s41598-021-81137-3.
Åhlén, I., Vigouroux, G., Destouni, G., Pietroń, J., Ghajarnia, N., Anaya, J., Blanco, J., Borja, S., Chalov, S., Chun, K. P., Clerici, N., Desormeaux, A., Girard, P., Gorelits, O., Hansen, A., Jaramillo, F., Kalantari, Z., Labbaci, A., Licero-Villanueva, L., Livsey, J., Maneas, G., Pisarello, K. L. M., Pahani, D. M., Palomino-Ángel, S., Price, R., Ricaurte-Villota, C., Fernanda Ricaurte, L., Rivera-Monroy, V. H., Rodriguez, A., Rodriguez, E., Salgado, J., Sannel, B., Seifollahi-Aghmiuni, S., Simard, M., Sjöberg, Y., Terskii, P., Thorslund, J., Zamora, D. A., & Jarsjö, J. (2021). Hydro-climatic changes of wetlandscapes across the world. Scientific reports, 11(1), 2754. https://doi.org/10.1038/s41598-021-81137-3
Åhlén, I, et al. "Hydro-climatic changes of wetlandscapes across the world." Scientific reports vol. 11,1 (2021): 2754. doi: https://doi.org/10.1038/s41598-021-81137-3
Åhlén I, Vigouroux G, Destouni G, Pietroń J, Ghajarnia N, Anaya J, Blanco J, Borja S, Chalov S, Chun KP, Clerici N, Desormeaux A, Girard P, Gorelits O, Hansen A, Jaramillo F, Kalantari Z, Labbaci A, Licero-Villanueva L, Livsey J, Maneas G, Pisarello KLM, Pahani DM, Palomino-Ángel S, Price R, Ricaurte-Villota C, Fernanda Ricaurte L, Rivera-Monroy VH, Rodriguez A, Rodriguez E, Salgado J, Sannel B, Seifollahi-Aghmiuni S, Simard M, Sjöberg Y, Terskii P, Thorslund J, Zamora DA, Jarsjö J. Hydro-climatic changes of wetlandscapes across the world. Sci Rep. 2021 Feb 02;11(1):2754. doi: 10.1038/s41598-021-81137-3. PMID: 33531523; PMCID: PMC7854620.
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Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families.

Molecular psychiatry

Cao X, Zhang Y, Abdulkadir M, Deng L, Fernandez TV, Garcia-Delgar B, Hagstrøm J, Hoekstra PJ, King RA, Koesterich J, Kuperman S, Morer A, Nasello C, Plessen KJ, Thackray JK, Zhou L, Dietrich A, Tischfield JA, Heiman GA, Xing J.
PMID: 33837273
Mol Psychiatry. 2021 Nov;26(11):6937-6951. doi: 10.1038/s41380-021-01094-1. Epub 2021 Apr 09.

Tourette's Disorder (TD) is a neurodevelopmental disorder (NDD) that affects about 0.7% of the population and is one of the most heritable NDDs. Nevertheless, because of its polygenic nature and genetic heterogeneity, the genetic etiology of TD is not...

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Cao X, Zhang Y, Abdulkadir M, et al. Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Mol Psychiatry. 2021;26(11):6937-6951doi: 10.1038/s41380-021-01094-1.
Cao, X., Zhang, Y., Abdulkadir, M., Deng, L., Fernandez, T. V., Garcia-Delgar, B., Hagstrøm, J., Hoekstra, P. J., King, R. A., Koesterich, J., Kuperman, S., Morer, A., Nasello, C., Plessen, K. J., Thackray, J. K., Zhou, L., Dietrich, A., Tischfield, J. A., Heiman, G. A., & Xing, J. (2021). Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Molecular psychiatry, 26(11), 6937-6951. https://doi.org/10.1038/s41380-021-01094-1
Cao, Xiaolong, et al. "Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families." Molecular psychiatry vol. 26,11 (2021): 6937-6951. doi: https://doi.org/10.1038/s41380-021-01094-1
Cao X, Zhang Y, Abdulkadir M, Deng L, Fernandez TV, Garcia-Delgar B, Hagstrøm J, Hoekstra PJ, King RA, Koesterich J, Kuperman S, Morer A, Nasello C, Plessen KJ, Thackray JK, Zhou L, Dietrich A, Tischfield JA, Heiman GA, Xing J. Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Mol Psychiatry. 2021 Nov;26(11):6937-6951. doi: 10.1038/s41380-021-01094-1. Epub 2021 Apr 09. PMID: 33837273; PMCID: PMC8501157.
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Role of adult hippocampal neurogenesis in the antidepressant actions of lactate.

Molecular psychiatry

Carrard A, Cassé F, Carron C, Burlet-Godinot S, Toni N, Magistretti PJ, Martin JL.
PMID: 33990772
Mol Psychiatry. 2021 Nov;26(11):6723-6735. doi: 10.1038/s41380-021-01122-0. Epub 2021 May 14.

In addition to its role as a neuronal energy substrate and signaling molecule involved in synaptic plasticity and memory consolidation, recent evidence shows that lactate produces antidepressant effects in animal models. However, the mechanisms underpinning lactate's antidepressant actions remain...

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Carrard A, Cassé F, Carron C, et al. Role of adult hippocampal neurogenesis in the antidepressant actions of lactate. Mol Psychiatry. 2021;26(11):6723-6735doi: 10.1038/s41380-021-01122-0.
Carrard, A., Cassé, F., Carron, C., Burlet-Godinot, S., Toni, N., Magistretti, P. J., & Martin, J. L. (2021). Role of adult hippocampal neurogenesis in the antidepressant actions of lactate. Molecular psychiatry, 26(11), 6723-6735. https://doi.org/10.1038/s41380-021-01122-0
Carrard, Anthony, et al. "Role of adult hippocampal neurogenesis in the antidepressant actions of lactate." Molecular psychiatry vol. 26,11 (2021): 6723-6735. doi: https://doi.org/10.1038/s41380-021-01122-0
Carrard A, Cassé F, Carron C, Burlet-Godinot S, Toni N, Magistretti PJ, Martin JL. Role of adult hippocampal neurogenesis in the antidepressant actions of lactate. Mol Psychiatry. 2021 Nov;26(11):6723-6735. doi: 10.1038/s41380-021-01122-0. Epub 2021 May 14. PMID: 33990772.
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Bioengineered miR-124-3p prodrug selectively alters the proteome of human carcinoma cells to control multiple cellular components and lung metastasis .

Acta pharmaceutica Sinica. B

Deng L, Petrek H, Tu MJ, Batra N, Yu AX, Yu AM.
PMID: 35024318
Acta Pharm Sin B. 2021 Dec;11(12):3950-3965. doi: 10.1016/j.apsb.2021.07.027. Epub 2021 Aug 17.

With the understanding of microRNA (miRNA or miR) functions in tumor initiation, progression, and metastasis, efforts are underway to develop new miRNA-based therapies. Very recently, we demonstrated effectiveness of a novel humanized bioengineered miR-124-3p prodrug in controlling spontaneous lung...

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Deng L, Petrek H, Tu MJ, et al. Bioengineered miR-124-3p prodrug selectively alters the proteome of human carcinoma cells to control multiple cellular components and lung metastasis . Acta Pharm Sin B. 2021;11(12):3950-3965doi: 10.1016/j.apsb.2021.07.027.
Deng, L., Petrek, H., Tu, M. J., Batra, N., Yu, A. X., & Yu, A. M. (2021). Bioengineered miR-124-3p prodrug selectively alters the proteome of human carcinoma cells to control multiple cellular components and lung metastasis . Acta pharmaceutica Sinica. B, 11(12), 3950-3965. https://doi.org/10.1016/j.apsb.2021.07.027
Deng, Linglong, et al. "Bioengineered miR-124-3p prodrug selectively alters the proteome of human carcinoma cells to control multiple cellular components and lung metastasis ." Acta pharmaceutica Sinica. B vol. 11,12 (2021): 3950-3965. doi: https://doi.org/10.1016/j.apsb.2021.07.027
Deng L, Petrek H, Tu MJ, Batra N, Yu AX, Yu AM. Bioengineered miR-124-3p prodrug selectively alters the proteome of human carcinoma cells to control multiple cellular components and lung metastasis . Acta Pharm Sin B. 2021 Dec;11(12):3950-3965. doi: 10.1016/j.apsb.2021.07.027. Epub 2021 Aug 17. PMID: 35024318; PMCID: PMC8727917.
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Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families.

Molecular psychiatry

Cao X, Zhang Y, Abdulkadir M, Deng L, Fernandez TV, Garcia-Delgar B, Hagstrøm J, Hoekstra PJ, King RA, Koesterich J, Kuperman S, Morer A, Nasello C, Plessen KJ, Thackray JK, Zhou L, Dietrich A, Tischfield JA, Heiman GA, Xing J.
PMID: 33837273
Mol Psychiatry. 2021 Nov;26(11):6937-6951. doi: 10.1038/s41380-021-01094-1. Epub 2021 Apr 09.

Tourette's Disorder (TD) is a neurodevelopmental disorder (NDD) that affects about 0.7% of the population and is one of the most heritable NDDs. Nevertheless, because of its polygenic nature and genetic heterogeneity, the genetic etiology of TD is not...

Cite
Cao X, Zhang Y, Abdulkadir M, et al. Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Mol Psychiatry. 2021;26(11):6937-6951doi: 10.1038/s41380-021-01094-1.
Cao, X., Zhang, Y., Abdulkadir, M., Deng, L., Fernandez, T. V., Garcia-Delgar, B., Hagstrøm, J., Hoekstra, P. J., King, R. A., Koesterich, J., Kuperman, S., Morer, A., Nasello, C., Plessen, K. J., Thackray, J. K., Zhou, L., Dietrich, A., Tischfield, J. A., Heiman, G. A., & Xing, J. (2021). Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Molecular psychiatry, 26(11), 6937-6951. https://doi.org/10.1038/s41380-021-01094-1
Cao, Xiaolong, et al. "Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families." Molecular psychiatry vol. 26,11 (2021): 6937-6951. doi: https://doi.org/10.1038/s41380-021-01094-1
Cao X, Zhang Y, Abdulkadir M, Deng L, Fernandez TV, Garcia-Delgar B, Hagstrøm J, Hoekstra PJ, King RA, Koesterich J, Kuperman S, Morer A, Nasello C, Plessen KJ, Thackray JK, Zhou L, Dietrich A, Tischfield JA, Heiman GA, Xing J. Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Mol Psychiatry. 2021 Nov;26(11):6937-6951. doi: 10.1038/s41380-021-01094-1. Epub 2021 Apr 09. PMID: 33837273; PMCID: PMC8501157.
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Risk of metachronous peritoneal metastases in patients with pT4a versus pT4b colon cancer: An international multicentre cohort study.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Bastiaenen VP, Aalbers AGJ, Arjona-Sánchez A, Bellato V, van der Bilt JDW, D'Hoore AD, Espinosa-Redondo E, Klaver CEL, Nagtegaal ID, van Ramshorst B, van Santvoort HC, Sica GS, Snaebjornsson P, Wasmann KATGM, de Wilt JHW, Wolthuis AM, Tanis PJ.
PMID: 34030920
Eur J Surg Oncol. 2021 Sep;47(9):2405-2413. doi: 10.1016/j.ejso.2021.05.009. Epub 2021 May 15.

INTRODUCTION: With evolving treatment strategies aiming at prevention or early detection of metachronous peritoneal metastases (PM), identification of high-risk colon cancer patients becomes increasingly important. This study aimed to evaluate differences between pT4a (peritoneal penetration) and pT4b (invasion of...

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Bastiaenen VP, Aalbers AGJ, Arjona-Sánchez A, et al. Risk of metachronous peritoneal metastases in patients with pT4a versus pT4b colon cancer: An international multicentre cohort study. Eur J Surg Oncol. 2021;47(9):2405-2413doi: 10.1016/j.ejso.2021.05.009.
Bastiaenen, V. P., Aalbers, A. G. J., Arjona-Sánchez, A., Bellato, V., van der Bilt, J. D. W., D'Hoore, A. D., Espinosa-Redondo, E., Klaver, C. E. L., Nagtegaal, I. D., van Ramshorst, B., van Santvoort, H. C., Sica, G. S., Snaebjornsson, P., Wasmann, K. A. T. G. M., de Wilt, J. H. W., Wolthuis, A. M., & Tanis, P. J. (2021). Risk of metachronous peritoneal metastases in patients with pT4a versus pT4b colon cancer: An international multicentre cohort study. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 47(9), 2405-2413. https://doi.org/10.1016/j.ejso.2021.05.009
Bastiaenen, Vivian P, et al. "Risk of metachronous peritoneal metastases in patients with pT4a versus pT4b colon cancer: An international multicentre cohort study." European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology vol. 47,9 (2021): 2405-2413. doi: https://doi.org/10.1016/j.ejso.2021.05.009
Bastiaenen VP, Aalbers AGJ, Arjona-Sánchez A, Bellato V, van der Bilt JDW, D'Hoore AD, Espinosa-Redondo E, Klaver CEL, Nagtegaal ID, van Ramshorst B, van Santvoort HC, Sica GS, Snaebjornsson P, Wasmann KATGM, de Wilt JHW, Wolthuis AM, Tanis PJ. Risk of metachronous peritoneal metastases in patients with pT4a versus pT4b colon cancer: An international multicentre cohort study. Eur J Surg Oncol. 2021 Sep;47(9):2405-2413. doi: 10.1016/j.ejso.2021.05.009. Epub 2021 May 15. PMID: 34030920.
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Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families.

Molecular psychiatry

Cao X, Zhang Y, Abdulkadir M, Deng L, Fernandez TV, Garcia-Delgar B, Hagstrøm J, Hoekstra PJ, King RA, Koesterich J, Kuperman S, Morer A, Nasello C, Plessen KJ, Thackray JK, Zhou L, Dietrich A, Tischfield JA, Heiman GA, Xing J.
PMID: 33837273
Mol Psychiatry. 2021 Apr 09; doi: 10.1038/s41380-021-01094-1. Epub 2021 Apr 09.

Tourette's Disorder (TD) is a neurodevelopmental disorder (NDD) that affects about 0.7% of the population and is one of the most heritable NDDs. Nevertheless, because of its polygenic nature and genetic heterogeneity, the genetic etiology of TD is not...

Cite
Cao X, Zhang Y, Abdulkadir M, et al. Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Mol Psychiatry. 2021;doi: 10.1038/s41380-021-01094-1.
Cao, X., Zhang, Y., Abdulkadir, M., Deng, L., Fernandez, T. V., Garcia-Delgar, B., Hagstrøm, J., Hoekstra, P. J., King, R. A., Koesterich, J., Kuperman, S., Morer, A., Nasello, C., Plessen, K. J., Thackray, J. K., Zhou, L., Dietrich, A., Tischfield, J. A., Heiman, G. A., & Xing, J. (2021). Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Molecular psychiatry, . https://doi.org/10.1038/s41380-021-01094-1
Cao, Xiaolong, et al. "Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families." Molecular psychiatry vol. (2021). doi: https://doi.org/10.1038/s41380-021-01094-1
Cao X, Zhang Y, Abdulkadir M, Deng L, Fernandez TV, Garcia-Delgar B, Hagstrøm J, Hoekstra PJ, King RA, Koesterich J, Kuperman S, Morer A, Nasello C, Plessen KJ, Thackray JK, Zhou L, Dietrich A, Tischfield JA, Heiman GA, Xing J. Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. Mol Psychiatry. 2021 Apr 09; doi: 10.1038/s41380-021-01094-1. Epub 2021 Apr 09. PMID: 33837273; PMCID: PMC8501157.
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Reply to: Peritoneal invasion and metachronous peritoneal metastases after colon cancer surgery: The role of homogeneous, reliable assessment and confounders.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Bastiaenen VP, Tanis PJ.
PMID: 34238641
Eur J Surg Oncol. 2021 Oct;47(10):2698-2699. doi: 10.1016/j.ejso.2021.06.032. Epub 2021 Jun 30.

No abstract available.

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Bastiaenen VP, Tanis PJ. Reply to: Peritoneal invasion and metachronous peritoneal metastases after colon cancer surgery: The role of homogeneous, reliable assessment and confounders. Eur J Surg Oncol. 2021;47(10):2698-2699doi: 10.1016/j.ejso.2021.06.032.
Bastiaenen, V. P., & Tanis, P. J. (2021). Reply to: Peritoneal invasion and metachronous peritoneal metastases after colon cancer surgery: The role of homogeneous, reliable assessment and confounders. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 47(10), 2698-2699. https://doi.org/10.1016/j.ejso.2021.06.032
Bastiaenen, Vivian P, and Tanis, Pieter J. "Reply to: Peritoneal invasion and metachronous peritoneal metastases after colon cancer surgery: The role of homogeneous, reliable assessment and confounders." European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology vol. 47,10 (2021): 2698-2699. doi: https://doi.org/10.1016/j.ejso.2021.06.032
Bastiaenen VP, Tanis PJ. Reply to: Peritoneal invasion and metachronous peritoneal metastases after colon cancer surgery: The role of homogeneous, reliable assessment and confounders. Eur J Surg Oncol. 2021 Oct;47(10):2698-2699. doi: 10.1016/j.ejso.2021.06.032. Epub 2021 Jun 30. PMID: 34238641.
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