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Showing 121 to 128 of 128 entries
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Renal haemodynamics and coronary atherosclerotic burden are associated in patients with hypertension and mild coronary artery disease.

Experimental and therapeutic medicine

Geraci G, Buccheri D, Zanoli L, Fatuzzo P, Di Natale K, Zammuto MM, Nardi E, Geraci C, Mancia E, Zambelli G, Piraino D, Signorelli SS, Granata A, Cottone S, Mule G.
PMID: 30906482
Exp Ther Med. 2019 Apr;17(4):3255-3263. doi: 10.3892/etm.2019.7279. Epub 2019 Feb 15.

Intrarenal hemodynamic alterations are independent predictors of cardiovascular events in different populations. It has been hypothesized that there is an association between renal hemodynamics and coronary atherosclerotic burden in patients with hypertension. Therefore, the present study examined the associations...

The impact of minimally oversized adeno-associated viral vectors encoding human factor VIII on vector potency in vivo.

Molecular therapy. Methods & clinical development

Kyostio-Moore S, Berthelette P, Piraino S, Sookdeo C, Nambiar B, Jackson R, Burnham B, O'Riordan CR, Cheng SH, Armentano D.
PMID: 26958574
Mol Ther Methods Clin Dev. 2016 Feb 24;3:16006. doi: 10.1038/mtm.2016.6. eCollection 2016.

Recombinant adeno-associated viral (rAAV) vectors containing oversized genomes provide transgene expression despite low efficiency packaging of complete genomes. Here, we characterized the properties of oversized rAAV2/8 vectors (up to 5.4 kb) encoding human factor VIII (FVIII) under the transcriptional...

Acute and spontaneous coronary thrombosis in non-culprit artery during percutaneous coronary intervention in myocardial infarction with ST-segment elevation: A "shocking" case.

International journal of cardiology. Heart & vasculature

Buccheri D, Carità P, Carella M, Piraino D, Chirco PR, Andolina G.
PMID: 28785706
Int J Cardiol Heart Vasc. 2015 Mar 11;9:52-54. doi: 10.1016/j.ijcha.2015.03.002. eCollection 2015 Dec 07.

No abstract available.

Bushveld superplume drove Proterozoic magmatism and metallogenesis in Australia.

Scientific reports

Fiorentini ML, O'Neill C, Giuliani A, Choi E, Maas R, Pirajno F, Foley S.
PMID: 33184371
Sci Rep. 2020 Nov 12;10(1):19729. doi: 10.1038/s41598-020-76800-0.

Large-scale mantle convective processes are commonly reflected in the emplacement of Large Igneous Provinces (LIPs). These are high-volume, short-duration magmatic events consisting mainly of extensive flood basalts and their associated plumbing systems. One of the most voluminous LIPs in...

Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients: A Pilot Randomised Controlled Trial.

Annals of the American Thoracic Society

Lewis K, Culgin S, Jaeschke R, Perri D, Marchildon C, Hassall K, Almubarak Y, Szczeklik W, Piraino T, Thabane L, Alqahtani KM, Alghamdi A, Alshahrani M, Alhazzani W.
PMID: 34242140
Ann Am Thorac Soc. 2021 Jul 09; doi: 10.1513/AnnalsATS.202103-390OC. Epub 2021 Jul 09.

RATIONALE: Laryngeal edema is a known complication of endotracheal intubation that may cause airway obstruction upon extubation. The only test available to predict this complication is the cuff leak test (CLT).OBJECTIVE: Given the uncertainty of the CLT's clinical utility,...

CHK1 inhibitor sensitizes resistant colorectal cancer stem cells to nortopsentin.

iScience

Di Franco S, Parrino B, Gaggianesi M, Pantina VD, Bianca P, Nicotra A, Mangiapane LR, Lo Iacono M, Ganduscio G, Veschi V, Brancato OR, Glaviano A, Turdo A, Pillitteri I, Colarossi L, Cascioferro S, Carbone D, Pecoraro C, Fiori ME, De Maria R, Todaro M, Screpanti I, Cirrincione G, Diana P, Stassi G.
PMID: 34169240
iScience. 2021 May 29;24(6):102664. doi: 10.1016/j.isci.2021.102664. eCollection 2021 Jun 25.

Limited therapeutic options are available for advanced colorectal cancer (CRC). Herein, we report that exposure to a neo-synthetic bis(indolyl)thiazole alkaloid analog, nortopsentin 234 (NORA234), leads to an initial reduction of proliferative and clonogenic potential of CRC sphere cells (CR-CSphCs),...

The Pressure Paradox: Abdominal Compression to Detect Lung Hyperinflation in COVID-19 Acute Respiratory Distress Syndrome.

American journal of respiratory and critical care medicine

Stavi D, Goffi A, Al Shalabi M, Piraino T, Chen L, Jackson R, Brochard L.
PMID: 34748470
Am J Respir Crit Care Med. 2022 Jan 15;205(2):245-247. doi: 10.1164/rccm.202104-1062IM.

No abstract available.

The Pressure Paradox: Abdominal Compression to Detect Lung Hyperinflation in COVID-19 Acute Respiratory Distress Syndrome.

American journal of respiratory and critical care medicine

Stavi D, Goffi A, Al Shalabi M, Piraino T, Chen L, Jackson R, Brochard L, Torgerson D.
PMID: 34748470
Am J Respir Crit Care Med. 2022 Jan 15;205(2):245-247. doi: 10.1164/rccm.202104-1062IM.

No abstract available.

Showing 121 to 128 of 128 entries