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Three Cases of Hereditary Tyrosinaemia Type 1: Neuropsychiatric Outcomes and Brain Imaging Following Treatment with NTBC.

JIMD reports

Walker H, Pitkanen M, Rahman Y, Barrington SF.
PMID: 29143197
JIMD Rep. 2018;40:97-103. doi: 10.1007/8904_2017_69. Epub 2017 Nov 16.

AIM: To examine neuropsychiatric outcomes in adults with hereditary tyrosinaemia type I (HT-1), treated with 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC) and correlate these with functional imaging as well as with tyrosine and phenylalanine-tyrosine (Phe:Tyr) ratios.DESIGN: We retrospectively reviewed the medical records of...

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Walker H, Pitkanen M, Rahman Y, et al. Three Cases of Hereditary Tyrosinaemia Type 1: Neuropsychiatric Outcomes and Brain Imaging Following Treatment with NTBC. JIMD Rep. 2017;40:97-103doi: 10.1007/8904_2017_69.
Walker, H., Pitkanen, M., Rahman, Y., & Barrington, S. F. (2018). Three Cases of Hereditary Tyrosinaemia Type 1: Neuropsychiatric Outcomes and Brain Imaging Following Treatment with NTBC. JIMD reports, 4097-103. https://doi.org/10.1007/8904_2017_69
Walker, Helen, et al. "Three Cases of Hereditary Tyrosinaemia Type 1: Neuropsychiatric Outcomes and Brain Imaging Following Treatment with NTBC." JIMD reports vol. 40 (2018): 97-103. doi: https://doi.org/10.1007/8904_2017_69
Walker H, Pitkanen M, Rahman Y, Barrington SF. Three Cases of Hereditary Tyrosinaemia Type 1: Neuropsychiatric Outcomes and Brain Imaging Following Treatment with NTBC. JIMD Rep. 2018;40:97-103. doi: 10.1007/8904_2017_69. Epub 2017 Nov 16. PMID: 29143197; PMCID: PMC6122041.
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On-chip integrated vertically aligned carbon nanotube based super- and pseudocapacitors.

Scientific reports

Pitkänen O, Järvinen T, Cheng H, Lorite GS, Dombovari A, Rieppo L, Talapatra S, Duong HM, Tóth G, Juhász KL, Kónya Z, Kukovecz A, Ajayan PM, Vajtai R, Kordás K.
PMID: 29185493
Sci Rep. 2017 Nov 29;7(1):16594. doi: 10.1038/s41598-017-16604-x.

On-chip energy storage and management will have transformative impacts in developing advanced electronic platforms with built-in energy needs for operation of integrated circuits driving a microprocessor. Though success in growing stand-alone energy storage elements such as electrochemical capacitors (super...

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Pitkänen O, Järvinen T, Cheng H, et al. On-chip integrated vertically aligned carbon nanotube based super- and pseudocapacitors. Sci Rep. 2017;7(1):16594doi: 10.1038/s41598-017-16604-x.
Pitkänen, O., Järvinen, T., Cheng, H., Lorite, G. S., Dombovari, A., Rieppo, L., Talapatra, S., Duong, H. M., Tóth, G., Juhász, K. L., Kónya, Z., Kukovecz, A., Ajayan, P. M., Vajtai, R., & Kordás, K. (2017). On-chip integrated vertically aligned carbon nanotube based super- and pseudocapacitors. Scientific reports, 7(1), 16594. https://doi.org/10.1038/s41598-017-16604-x
Pitkänen, O, et al. "On-chip integrated vertically aligned carbon nanotube based super- and pseudocapacitors." Scientific reports vol. 7,1 (2017): 16594. doi: https://doi.org/10.1038/s41598-017-16604-x
Pitkänen O, Järvinen T, Cheng H, Lorite GS, Dombovari A, Rieppo L, Talapatra S, Duong HM, Tóth G, Juhász KL, Kónya Z, Kukovecz A, Ajayan PM, Vajtai R, Kordás K. On-chip integrated vertically aligned carbon nanotube based super- and pseudocapacitors. Sci Rep. 2017 Nov 29;7(1):16594. doi: 10.1038/s41598-017-16604-x. PMID: 29185493; PMCID: PMC5707404.
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A major decrease of viral acute gastroenteritis in hospitalized Finnish children as rotavirus returns as the most detected pathogen.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

Pitkänen O, Markkula J, Hemming-Harlo M.
PMID: 34775115
Int J Infect Dis. 2021 Nov 11; doi: 10.1016/j.ijid.2021.11.016. Epub 2021 Nov 11.

INTRODUCTION: We assessed the prevalence and circulating genotypes of rotavirus, norovirus and sapovirus in children. The results were compared to previous surveillance studies from 2006-2008, 2009-2011 and 2012-2014 with similar methodology and setting, covering the start of universal vaccination...

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Pitkänen O, Markkula J, Hemming-Harlo M. A major decrease of viral acute gastroenteritis in hospitalized Finnish children as rotavirus returns as the most detected pathogen. Int J Infect Dis. 2021;doi: 10.1016/j.ijid.2021.11.016.
Pitkänen, O., Markkula, J., & Hemming-Harlo, M. (2021). A major decrease of viral acute gastroenteritis in hospitalized Finnish children as rotavirus returns as the most detected pathogen. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, . https://doi.org/10.1016/j.ijid.2021.11.016
Pitkänen, Oskari, et al. "A major decrease of viral acute gastroenteritis in hospitalized Finnish children as rotavirus returns as the most detected pathogen." International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases vol. (2021). doi: https://doi.org/10.1016/j.ijid.2021.11.016
Pitkänen O, Markkula J, Hemming-Harlo M. A major decrease of viral acute gastroenteritis in hospitalized Finnish children as rotavirus returns as the most detected pathogen. Int J Infect Dis. 2021 Nov 11; doi: 10.1016/j.ijid.2021.11.016. Epub 2021 Nov 11. PMID: 34775115.
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Identification of clinically relevant biomarkers of epileptogenesis - a strategic roadmap.

Nature reviews. Neurology

Simonato M, Agoston DV, Brooks-Kayal A, Dulla C, Fureman B, Henshall DC, Pitkänen A, Theodore WH, Twyman RE, Kobeissy FH, Wang KK, Whittemore V, Wilcox KS.
PMID: 33594276
Nat Rev Neurol. 2021 Apr;17(4):231-242. doi: 10.1038/s41582-021-00461-4. Epub 2021 Feb 16.

Onset of many forms of epilepsy occurs after an initial epileptogenic insult or as a result of an identified genetic defect. Given that the precipitating insult is known, these epilepsies are, in principle, amenable to secondary prevention. However, development...

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Simonato M, Agoston DV, Brooks-Kayal A, et al. Identification of clinically relevant biomarkers of epileptogenesis - a strategic roadmap. Nat Rev Neurol. 2021;17(4):231-242doi: 10.1038/s41582-021-00461-4.
Simonato, M., Agoston, D. V., Brooks-Kayal, A., Dulla, C., Fureman, B., Henshall, D. C., Pitkänen, A., Theodore, W. H., Twyman, R. E., Kobeissy, F. H., Wang, K. K., Whittemore, V., & Wilcox, K. S. (2021). Identification of clinically relevant biomarkers of epileptogenesis - a strategic roadmap. Nature reviews. Neurology, 17(4), 231-242. https://doi.org/10.1038/s41582-021-00461-4
Simonato, Michele, et al. "Identification of clinically relevant biomarkers of epileptogenesis - a strategic roadmap." Nature reviews. Neurology vol. 17,4 (2021): 231-242. doi: https://doi.org/10.1038/s41582-021-00461-4
Simonato M, Agoston DV, Brooks-Kayal A, Dulla C, Fureman B, Henshall DC, Pitkänen A, Theodore WH, Twyman RE, Kobeissy FH, Wang KK, Whittemore V, Wilcox KS. Identification of clinically relevant biomarkers of epileptogenesis - a strategic roadmap. Nat Rev Neurol. 2021 Apr;17(4):231-242. doi: 10.1038/s41582-021-00461-4. Epub 2021 Feb 16. PMID: 33594276.
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Synergistic associations of cognitive and motor impairments with functional outcome in covert cerebral small vessel disease.

European journal of neurology

Jokinen H, Laakso HM, Ahlström M, Arola A, Lempiäinen J, Pitkänen J, Paajanen T, Sikkes SAM, Koikkalainen J, Lötjönen J, Korvenoja A, Erkinjuntti T, Melkas S.
PMID: 34528346
Eur J Neurol. 2022 Jan;29(1):158-167. doi: 10.1111/ene.15108. Epub 2021 Sep 26.

BACKGROUND: Cognitive and motor impairments are the key clinical manifestations of cerebral small vessel disease (SVD), but their combined effects on functional outcome have not been elucidated. This study investigated the interactions and mediating effects of cognitive and motor...

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Jokinen H, Laakso HM, Ahlström M, et al. Synergistic associations of cognitive and motor impairments with functional outcome in covert cerebral small vessel disease. Eur J Neurol. 2021;29(1):158-167doi: 10.1111/ene.15108.
Jokinen, H., Laakso, H. M., Ahlström, M., Arola, A., Lempiäinen, J., Pitkänen, J., Paajanen, T., Sikkes, S. A. M., Koikkalainen, J., Lötjönen, J., Korvenoja, A., Erkinjuntti, T., & Melkas, S. (2022). Synergistic associations of cognitive and motor impairments with functional outcome in covert cerebral small vessel disease. European journal of neurology, 29(1), 158-167. https://doi.org/10.1111/ene.15108
Jokinen, Hanna, et al. "Synergistic associations of cognitive and motor impairments with functional outcome in covert cerebral small vessel disease." European journal of neurology vol. 29,1 (2022): 158-167. doi: https://doi.org/10.1111/ene.15108
Jokinen H, Laakso HM, Ahlström M, Arola A, Lempiäinen J, Pitkänen J, Paajanen T, Sikkes SAM, Koikkalainen J, Lötjönen J, Korvenoja A, Erkinjuntti T, Melkas S. Synergistic associations of cognitive and motor impairments with functional outcome in covert cerebral small vessel disease. Eur J Neurol. 2022 Jan;29(1):158-167. doi: 10.1111/ene.15108. Epub 2021 Sep 26. PMID: 34528346.
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The Use of Ribosomal RNA as a Microbial Source Tracking Target Highlights the Assay Host-Specificity Requirement in Water Quality Assessments.

Frontiers in microbiology

Rytkönen A, Tiwari A, Hokajärvi AM, Uusheimo S, Vepsäläinen A, Tulonen T, Pitkänen T.
PMID: 34149662
Front Microbiol. 2021 Jun 02;12:673306. doi: 10.3389/fmicb.2021.673306. eCollection 2021.

For microbial source tracking (MST), the 16S ribosomal RNA genes (rDNA) of host-specific bacteria and mitochondrial DNA (mtDNA) of animal species, known to cause fecal contamination of water, have been commonly used as molecular targets. However, low levels of...

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Rytkönen A, Tiwari A, Hokajärvi AM, et al. The Use of Ribosomal RNA as a Microbial Source Tracking Target Highlights the Assay Host-Specificity Requirement in Water Quality Assessments. Front Microbiol. 2021;12:673306doi: 10.3389/fmicb.2021.673306.
Rytkönen, A., Tiwari, A., Hokajärvi, A. M., Uusheimo, S., Vepsäläinen, A., Tulonen, T., & Pitkänen, T. (2021). The Use of Ribosomal RNA as a Microbial Source Tracking Target Highlights the Assay Host-Specificity Requirement in Water Quality Assessments. Frontiers in microbiology, 12673306. https://doi.org/10.3389/fmicb.2021.673306
Rytkönen, Annastiina, et al. "The Use of Ribosomal RNA as a Microbial Source Tracking Target Highlights the Assay Host-Specificity Requirement in Water Quality Assessments." Frontiers in microbiology vol. 12 (2021): 673306. doi: https://doi.org/10.3389/fmicb.2021.673306
Rytkönen A, Tiwari A, Hokajärvi AM, Uusheimo S, Vepsäläinen A, Tulonen T, Pitkänen T. The Use of Ribosomal RNA as a Microbial Source Tracking Target Highlights the Assay Host-Specificity Requirement in Water Quality Assessments. Front Microbiol. 2021 Jun 02;12:673306. doi: 10.3389/fmicb.2021.673306. eCollection 2021. PMID: 34149662; PMCID: PMC8206488.
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Post-injury ventricular enlargement associates with iron in choroid plexus but not with seizure susceptibility nor lesion atrophy-6-month MRI follow-up after experimental traumatic brain injury.

Brain structure & function

Yasmin A, Pitkänen A, Andrade P, Paananen T, Gröhn O, Immonen R.
PMID: 34757444
Brain Struct Funct. 2021 Nov 10; doi: 10.1007/s00429-021-02395-5. Epub 2021 Nov 10.

Ventricular enlargement is one long-term consequence of a traumatic brain injury, and a risk factor for memory disorders and epilepsy. One underlying mechanisms of the chronic ventricular enlargement is disturbed cerebrospinal-fluid secretion or absorption by choroid plexus. We set...

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Yasmin A, Pitkänen A, Andrade P, et al. Post-injury ventricular enlargement associates with iron in choroid plexus but not with seizure susceptibility nor lesion atrophy-6-month MRI follow-up after experimental traumatic brain injury. Brain Struct Funct. 2021;doi: 10.1007/s00429-021-02395-5.
Yasmin, A., Pitkänen, A., Andrade, P., Paananen, T., Gröhn, O., & Immonen, R. (2021). Post-injury ventricular enlargement associates with iron in choroid plexus but not with seizure susceptibility nor lesion atrophy-6-month MRI follow-up after experimental traumatic brain injury. Brain structure & function, . https://doi.org/10.1007/s00429-021-02395-5
Yasmin, Amna, et al. "Post-injury ventricular enlargement associates with iron in choroid plexus but not with seizure susceptibility nor lesion atrophy-6-month MRI follow-up after experimental traumatic brain injury." Brain structure & function vol. (2021). doi: https://doi.org/10.1007/s00429-021-02395-5
Yasmin A, Pitkänen A, Andrade P, Paananen T, Gröhn O, Immonen R. Post-injury ventricular enlargement associates with iron in choroid plexus but not with seizure susceptibility nor lesion atrophy-6-month MRI follow-up after experimental traumatic brain injury. Brain Struct Funct. 2021 Nov 10; doi: 10.1007/s00429-021-02395-5. Epub 2021 Nov 10. PMID: 34757444.
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Surface Water Intrusion, Land Use Impacts, and Bacterial Community Composition in Shallow Groundwater Wells Supplying Potable Water in Sparsely Populated Areas of a Boreal Region.

Microbiology spectrum

Lyons KJ, Hokajärvi AM, Ikonen J, Kauppinen A, Miettinen IT, Pitkänen T, Rossi PM, Kujala K.
PMID: 34730413
Microbiol Spectr. 2021 Dec 22;9(3):e0017921. doi: 10.1128/Spectrum.00179-21. Epub 2021 Nov 03.

Rural communities often rely on groundwater for potable water supply. In this study, untreated groundwater samples from 28 shallow groundwater wells in Finland (

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Lyons KJ, Hokajärvi AM, Ikonen J, et al. Surface Water Intrusion, Land Use Impacts, and Bacterial Community Composition in Shallow Groundwater Wells Supplying Potable Water in Sparsely Populated Areas of a Boreal Region. Microbiol Spectr. 2021;9(3):e0017921doi: 10.1128/Spectrum.00179-21.
Lyons, K. J., Hokajärvi, A. M., Ikonen, J., Kauppinen, A., Miettinen, I. T., Pitkänen, T., Rossi, P. M., & Kujala, K. (2021). Surface Water Intrusion, Land Use Impacts, and Bacterial Community Composition in Shallow Groundwater Wells Supplying Potable Water in Sparsely Populated Areas of a Boreal Region. Microbiology spectrum, 9(3), e0017921. https://doi.org/10.1128/Spectrum.00179-21
Lyons, Kevin J, et al. "Surface Water Intrusion, Land Use Impacts, and Bacterial Community Composition in Shallow Groundwater Wells Supplying Potable Water in Sparsely Populated Areas of a Boreal Region." Microbiology spectrum vol. 9,3 (2021): e0017921. doi: https://doi.org/10.1128/Spectrum.00179-21
Lyons KJ, Hokajärvi AM, Ikonen J, Kauppinen A, Miettinen IT, Pitkänen T, Rossi PM, Kujala K. Surface Water Intrusion, Land Use Impacts, and Bacterial Community Composition in Shallow Groundwater Wells Supplying Potable Water in Sparsely Populated Areas of a Boreal Region. Microbiol Spectr. 2021 Dec 22;9(3):e0017921. doi: 10.1128/Spectrum.00179-21. Epub 2021 Nov 03. PMID: 34730413; PMCID: PMC8567237.
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Can the Brain Be Relativistic?.

Frontiers in neuroscience

Rastmanesh R, Pitkänen M.
PMID: 34220421
Front Neurosci. 2021 Jun 17;15:659860. doi: 10.3389/fnins.2021.659860. eCollection 2021.

No abstract available.

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Rastmanesh R, Pitkänen M. Can the Brain Be Relativistic?. Front Neurosci. 2021;15:659860doi: 10.3389/fnins.2021.659860.
Rastmanesh, R., & Pitkänen, M. (2021). Can the Brain Be Relativistic?. Frontiers in neuroscience, 15659860. https://doi.org/10.3389/fnins.2021.659860
Rastmanesh, Reza, and Pitkänen, Matti. "Can the Brain Be Relativistic?." Frontiers in neuroscience vol. 15 (2021): 659860. doi: https://doi.org/10.3389/fnins.2021.659860
Rastmanesh R, Pitkänen M. Can the Brain Be Relativistic?. Front Neurosci. 2021 Jun 17;15:659860. doi: 10.3389/fnins.2021.659860. eCollection 2021. PMID: 34220421; PMCID: PMC8250859.
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Genetic analyses of metabolic body weight, carcass weight and body conformation traits in Nordic dairy cattle.

Animal : an international journal of animal bioscience

Mehtiö T, Pitkänen T, Leino AM, Mäntysaari EA, Kempe R, Negussie E, Lidauer MH.
PMID: 34749067
Animal. 2021 Nov 05;15(12):100398. doi: 10.1016/j.animal.2021.100398. Epub 2021 Nov 05.

Improving feed efficiency in dairy cattle by animal breeding has started in the Nordic countries. One of the two traits included in the applied Saved feed index is called maintenance and it is based on the breeding values for...

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Mehtiö T, Pitkänen T, Leino AM, et al. Genetic analyses of metabolic body weight, carcass weight and body conformation traits in Nordic dairy cattle. Animal. 2021;15(12):100398doi: 10.1016/j.animal.2021.100398.
Mehtiö, T., Pitkänen, T., Leino, A. M., Mäntysaari, E. A., Kempe, R., Negussie, E., & Lidauer, M. H. (2021). Genetic analyses of metabolic body weight, carcass weight and body conformation traits in Nordic dairy cattle. Animal : an international journal of animal bioscience, 15(12), 100398. https://doi.org/10.1016/j.animal.2021.100398
Mehtiö, T, et al. "Genetic analyses of metabolic body weight, carcass weight and body conformation traits in Nordic dairy cattle." Animal : an international journal of animal bioscience vol. 15,12 (2021): 100398. doi: https://doi.org/10.1016/j.animal.2021.100398
Mehtiö T, Pitkänen T, Leino AM, Mäntysaari EA, Kempe R, Negussie E, Lidauer MH. Genetic analyses of metabolic body weight, carcass weight and body conformation traits in Nordic dairy cattle. Animal. 2021 Nov 05;15(12):100398. doi: 10.1016/j.animal.2021.100398. Epub 2021 Nov 05. PMID: 34749067.
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Showing 145 to 154 of 154 entries