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Showing 205 to 214 of 214 entries
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PAX-D: study protocol for a randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression.

Evidence-based mental health

Au-Yeung SK, Griffiths J, Roberts S, Edwards C, Yu LM, Bogacz R, Rendell J, Attenburrow MJ, Watson S, Chan F, Cipriani A, Cleare A, Harmer CJ, Kessler D, Evans J, Lewis G, Singh I, Simon J, Harrison PJ, Cowen P, Shanyinde M, Geddes J, Browning M.
PMID: 34810175
Evid Based Ment Health. 2021 Nov 22; doi: 10.1136/ebmental-2021-300282. Epub 2021 Nov 22.

INTRODUCTION: Clinical depression is usually treated in primary care with psychological therapies and antidepressant medication. However, when patients do not respond to at least two or more antidepressants within a depressive episode, they are considered to have treatment resistant...

Correction to: Cost-Utility Analysis of Discontinuing Antidepressants in England Primary Care Patients Compared with Long-Term Maintenance: The ANTLER Study.

Applied health economics and health policy

Clarke CS, Duffy L, Lewis G, Freemantle N, Gilbody S, Kendrick T, Kessler D, King M, Lanham P, Mangin D, Moore M, Nazareth I, Wiles N, Marston L, Hunter RM.
PMID: 34893957
Appl Health Econ Health Policy. 2021 Dec 11; doi: 10.1007/s40258-021-00708-7. Epub 2021 Dec 11.

No abstract available.

Cognitive style and drinking to cope: A prospective cohort study.

Addiction (Abingdon, England)

Corcoran E, Lewis G, Heron J, Hickman M, Lewis G.
PMID: 34338391
Addiction. 2021 Aug 02; doi: 10.1111/add.15655. Epub 2021 Aug 02.

BACKGROUND AND AIMS: Having a negative cognitive style may lead someone to feel hopeless about his or her situation and be more likely to engage in coping-motivated drinking. We, therefore, aimed to investigate the association between cognitive style and...

Association of Emotion Regulation Trajectories in Childhood With Anorexia Nervosa and Atypical Anorexia Nervosa in Early Adolescence.

JAMA psychiatry

Henderson M, Bould H, Flouri E, Harrison A, Lewis G, Lewis G, Srinivasan R, Stafford J, Warne N, Solmi F.
PMID: 34232251
JAMA Psychiatry. 2021 Nov 01;78(11):1249-1257. doi: 10.1001/jamapsychiatry.2021.1599.

IMPORTANCE: People with anorexia nervosa often experience difficulties regulating their emotions. There is no longitudinal evidence as to whether these differences are already present in childhood or when they begin to emerge.OBJECTIVE: To investigate the association between emotion regulation...

Life events and treatment prognosis for depression: A systematic review and individual patient data meta-analysis.

Journal of affective disorders

Buckman JEJ, Saunders R, Arundell LL, Oshinowo ID, Cohen ZD, O'Driscoll C, Barnett P, Stott J, Ambler G, Gilbody S, Hollon SD, Kendrick T, Watkins E, Eley TC, Skelton M, Wiles N, Kessler D, DeRubeis RJ, Lewis G, Pilling S.
PMID: 34920035
J Affect Disord. 2021 Dec 14;299:298-308. doi: 10.1016/j.jad.2021.12.030. Epub 2021 Dec 14.

OBJECTIVE: To investigate associations between major life events and prognosis independent of treatment type: (1) after adjusting for clinical prognostic factors and socio-demographics; (2) amongst patients with depressive episodes at least six-months long; and (3) patients with a first...

Mental Health and Wellbeing of Retired Elite and Amateur Rugby Players and Non-contact Athletes and Associations with Sports-Related Concussion: The UK Rugby Health Project.

Sports medicine (Auckland, N.Z.)

Hind K, Konerth N, Entwistle I, Hume P, Theadom A, Lewis G, King D, Goodbourn T, Bottiglieri M, Ferraces-Riegas P, Ellison A, Chazot P.
PMID: 34792798
Sports Med. 2021 Nov 18; doi: 10.1007/s40279-021-01594-8. Epub 2021 Nov 18.

BACKGROUND: Concerns have intensified over the health and wellbeing of rugby union and league players, and, in particular, about the longer-term effects of concussion. The purpose of this study was to investigate whether there were differences in mental health,...

Facet- and Gas-Dependent Reshaping of Au Nanoplates by Plasma Treatment.

ACS nano

Ai R, Boukouvala C, Lewis G, Wang H, Zhang H, Lai Y, Huang H, Ringe E, Shao L, Wang J.
PMID: 34114456
ACS Nano. 2021 Jun 22;15(6):9860-9870. doi: 10.1021/acsnano.1c00861. Epub 2021 Jun 11.

The reshaping of metal nanocrystals on substrates is usually realized by pulsed laser irradiation or ion-beam milling with complex procedures. In this work, we demonstrate a simple method for reshaping immobilized Au nanoplates through plasma treatment. Au nanoplates can...

Connexin 43 confers chemoresistance through activating PI3K.

Oncogenesis

Pridham KJ, Shah F, Hutchings KR, Sheng KL, Guo S, Liu M, Kanabur P, Lamouille S, Lewis G, Morales M, Jourdan J, Grek CL, Ghatnekar GG, Varghese R, Kelly DF, Gourdie RG, Sheng Z.
PMID: 35022385
Oncogenesis. 2022 Jan 12;11(1):2. doi: 10.1038/s41389-022-00378-7.

Circumventing chemoresistance is crucial for effectively treating cancer including glioblastoma, a lethal brain cancer. The gap junction protein connexin 43 (Cx43) renders glioblastoma resistant to chemotherapy; however, targeting Cx43 is difficult because mechanisms underlying Cx43-mediated chemoresistance remain elusive. Here...

Do Students Learn Better with Pecha Kucha, an Alternative Presentation Format?.

Journal of microbiology & biology education

Liao MK, Lewis G, Winiski M.
PMID: 33294097
J Microbiol Biol Educ. 2020 Nov 12;21(3). doi: 10.1128/jmbe.v21i3.2111. eCollection 2020.

No abstract available.

Clinical and radiographic outcomes following retrograde SIGN fin nailing for femoral shaft fractures.

OTA international : the open access journal of orthopaedic trauma

Wilson NM, Moen MT, Shaw JT, Graf RM, Behlmer RJ, Simske NM, Zirkle LG, Whiting PS.
PMID: 33937709
OTA Int. 2020 Aug 05;3(3):e086. doi: 10.1097/OI9.0000000000000086. eCollection 2020 Sep.

PURPOSE: The Surgical Implant Generation Network (SIGN) intramedullary nail was designed for use in resource limited settings which often lack fluoroscopy, specialized fracture tables, and power reaming. A newer design iteration, the SIGN Fin nail, was developed to further...

Showing 205 to 214 of 214 entries