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Showing 13 to 24 of 74 entries
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Emerging antimicrobial resistance among .

CMAJ open

Mineau S, Kozak R, Kissoon M, Paterson A, Oppedisano A, Douri F, Gogan K, Willey BM, McGeer A, Poutanen SM.
PMID: 30510041
CMAJ Open. 2018 Dec 03;6(4):E580-E586. doi: 10.9778/cmajo.20180039. Print 2018.

BACKGROUND: Enterobacteriaceae that produce extended-spectrum β-lactamase (ESBL) have emerged as a serious threat, with variable rates depending on geographic region. We determined the prevalence of ESBL-producing METHODS: All patients with RESULTS: The proportion of ESBL-producing INTERPRETATION: We observed a...

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Mineau S, Kozak R, Kissoon M, et al. Emerging antimicrobial resistance among . CMAJ Open. 2018;6(4):E580-E586doi: 10.9778/cmajo.20180039.
Mineau, S., Kozak, R., Kissoon, M., Paterson, A., Oppedisano, A., Douri, F., Gogan, K., Willey, B. M., McGeer, A., & Poutanen, S. M. (2018). Emerging antimicrobial resistance among . CMAJ open, 6(4), E580-E586. https://doi.org/10.9778/cmajo.20180039
Mineau, Sophie, et al. "Emerging antimicrobial resistance among ." CMAJ open vol. 6,4 (2018): E580-E586. doi: https://doi.org/10.9778/cmajo.20180039
Mineau S, Kozak R, Kissoon M, Paterson A, Oppedisano A, Douri F, Gogan K, Willey BM, McGeer A, Poutanen SM. Emerging antimicrobial resistance among . CMAJ Open. 2018 Dec 03;6(4):E580-E586. doi: 10.9778/cmajo.20180039. Print 2018. PMID: 30510041; PMCID: PMC6277254.
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Thermal Isomerization of Hydroxyazobenzenes as a Platform for Vapor Sensing.

ACS macro letters

Poutanen M, Ahmed Z, Rautkari L, Ikkala O, Priimagi A.
PMID: 29607244
ACS Macro Lett. 2018 Mar 20;7(3):381-386. doi: 10.1021/acsmacrolett.8b00093. Epub 2018 Mar 10.

Photoisomerization of azobenzene derivatives is a versatile tool for devising light-responsive materials for a broad range of applications in photonics, robotics, microfabrication, and biomaterials science. Some applications rely on fast isomerization kinetics, while for others, bistable azobenzenes are preferred....

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Poutanen M, Ahmed Z, Rautkari L, et al. Thermal Isomerization of Hydroxyazobenzenes as a Platform for Vapor Sensing. ACS Macro Lett. 2018;7(3):381-386doi: 10.1021/acsmacrolett.8b00093.
Poutanen, M., Ahmed, Z., Rautkari, L., Ikkala, O., & Priimagi, A. (2018). Thermal Isomerization of Hydroxyazobenzenes as a Platform for Vapor Sensing. ACS macro letters, 7(3), 381-386. https://doi.org/10.1021/acsmacrolett.8b00093
Poutanen, Mikko, et al. "Thermal Isomerization of Hydroxyazobenzenes as a Platform for Vapor Sensing." ACS macro letters vol. 7,3 (2018): 381-386. doi: https://doi.org/10.1021/acsmacrolett.8b00093
Poutanen M, Ahmed Z, Rautkari L, Ikkala O, Priimagi A. Thermal Isomerization of Hydroxyazobenzenes as a Platform for Vapor Sensing. ACS Macro Lett. 2018 Mar 20;7(3):381-386. doi: 10.1021/acsmacrolett.8b00093. Epub 2018 Mar 10. PMID: 29607244; PMCID: PMC5871339.
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Inactivation of the androgen receptor in bone-forming cells leads to trabecular bone loss in adult female mice.

BoneKEy reports

Määttä JA, Büki KG, Ivaska KK, Nieminen-Pihala V, Elo TD, Kähkönen T, Poutanen M, Härkönen P, Väänänen K.
PMID: 24422138
Bonekey Rep. 2013 Nov 06;2:440. doi: 10.1038/bonekey.2013.174. eCollection 2013.

Removal of the androgen receptor (AR) from bone-forming cells has been shown to reduce trabecular bone volume in male mice. In female mice, the role of AR in the regulation of bone homeostasis has been poorly understood. We generated...

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Määttä JA, Büki KG, Ivaska KK, et al. Inactivation of the androgen receptor in bone-forming cells leads to trabecular bone loss in adult female mice. Bonekey Rep. 2013;2:440doi: 10.1038/bonekey.2013.174.
Määttä, J. A., Büki, K. G., Ivaska, K. K., Nieminen-Pihala, V., Elo, T. D., Kähkönen, T., Poutanen, M., Härkönen, P., & Väänänen, K. (2013). Inactivation of the androgen receptor in bone-forming cells leads to trabecular bone loss in adult female mice. BoneKEy reports, 2440. https://doi.org/10.1038/bonekey.2013.174
Määttä, Jorma A, et al. "Inactivation of the androgen receptor in bone-forming cells leads to trabecular bone loss in adult female mice." BoneKEy reports vol. 2 (2013): 440. doi: https://doi.org/10.1038/bonekey.2013.174
Määttä JA, Büki KG, Ivaska KK, Nieminen-Pihala V, Elo TD, Kähkönen T, Poutanen M, Härkönen P, Väänänen K. Inactivation of the androgen receptor in bone-forming cells leads to trabecular bone loss in adult female mice. Bonekey Rep. 2013 Nov 06;2:440. doi: 10.1038/bonekey.2013.174. eCollection 2013. PMID: 24422138; PMCID: PMC3844973.
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The effect of fibre amount, energy level and viscosity of beverages containing oat fibre supplement on perceived satiety.

Food & nutrition research

Lyly M, Ohls N, Lähteenmäki L, Salmenkallio-Marttila M, Liukkonen KH, Karhunen L, Poutanen K.
PMID: 20401343
Food Nutr Res. 2010 Apr 14;54. doi: 10.3402/fnr.v54i0.2149.

BACKGROUND: Soluble fibre has been proposed to suppress appetite-related perceptions and it could thus contribute favourably to the regulation of energy intake and the increasing obesity problem.OBJECTIVE: To investigate the effect of an oat ingredient rich in beta-glucan on...

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Lyly M, Ohls N, Lähteenmäki L, et al. The effect of fibre amount, energy level and viscosity of beverages containing oat fibre supplement on perceived satiety. Food Nutr Res. 2010;54doi: 10.3402/fnr.v54i0.2149.
Lyly, M., Ohls, N., Lähteenmäki, L., Salmenkallio-Marttila, M., Liukkonen, K. H., Karhunen, L., & Poutanen, K. (2010). The effect of fibre amount, energy level and viscosity of beverages containing oat fibre supplement on perceived satiety. Food & nutrition research, 54. https://doi.org/10.3402/fnr.v54i0.2149
Lyly, Marika, et al. "The effect of fibre amount, energy level and viscosity of beverages containing oat fibre supplement on perceived satiety." Food & nutrition research vol. 54 (2010). doi: https://doi.org/10.3402/fnr.v54i0.2149
Lyly M, Ohls N, Lähteenmäki L, Salmenkallio-Marttila M, Liukkonen KH, Karhunen L, Poutanen K. The effect of fibre amount, energy level and viscosity of beverages containing oat fibre supplement on perceived satiety. Food Nutr Res. 2010 Apr 14;54. doi: 10.3402/fnr.v54i0.2149. PMID: 20401343; PMCID: PMC2855638.
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Distinct Characteristics of Rye and Wheat Breads Impact on Their in Vitro Gastric Disintegration and in Vivo Glucose and Insulin Responses.

Foods (Basel, Switzerland)

Nordlund E, Katina K, Mykkänen H, Poutanen K.
PMID: 28231119
Foods. 2016 Mar 25;5(2). doi: 10.3390/foods5020024.

Disintegration of rye and wheat breads during

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Nordlund E, Katina K, Mykkänen H, et al. Distinct Characteristics of Rye and Wheat Breads Impact on Their in Vitro Gastric Disintegration and in Vivo Glucose and Insulin Responses. Foods. 2016;5(2)doi: 10.3390/foods5020024.
Nordlund, E., Katina, K., Mykkänen, H., & Poutanen, K. (2016). Distinct Characteristics of Rye and Wheat Breads Impact on Their in Vitro Gastric Disintegration and in Vivo Glucose and Insulin Responses. Foods (Basel, Switzerland), 5(2), . https://doi.org/10.3390/foods5020024
Nordlund, Emilia, et al. "Distinct Characteristics of Rye and Wheat Breads Impact on Their in Vitro Gastric Disintegration and in Vivo Glucose and Insulin Responses." Foods (Basel, Switzerland) vol. 5,2 (2016). doi: https://doi.org/10.3390/foods5020024
Nordlund E, Katina K, Mykkänen H, Poutanen K. Distinct Characteristics of Rye and Wheat Breads Impact on Their in Vitro Gastric Disintegration and in Vivo Glucose and Insulin Responses. Foods. 2016 Mar 25;5(2). doi: 10.3390/foods5020024. PMID: 28231119; PMCID: PMC5302334.
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Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids.

Clinical nutrition (Edinburgh, Scotland)

Gürdeniz G, Uusitupa M, Hermansen K, Savolainen MJ, Schwab U, Kolehmainen M, Brader L, Cloetens L, Herzig KH, Hukkanen J, Rosqvist F, Ulven SM, Gunnarsdóttir I, Thorsdottir I, Oresic M, Poutanen KS, Risérus U, Åkesson B, Dragsted LO.
PMID: 35007813
Clin Nutr. 2021 Dec 25;41(2):441-451. doi: 10.1016/j.clnu.2021.12.031. Epub 2021 Dec 25.

BACKGROUND & AIMS: Intake assessment in multicenter trials is challenging, yet important for accurate outcome evaluation. The present study aimed to characterize a multicenter randomized controlled trial with a healthy Nordic diet (HND) compared to a Control diet (CD)...

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Gürdeniz G, Uusitupa M, Hermansen K, et al. Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids. Clin Nutr. 2021;41(2):441-451doi: 10.1016/j.clnu.2021.12.031.
Gürdeniz, G., Uusitupa, M., Hermansen, K., Savolainen, M. J., Schwab, U., Kolehmainen, M., Brader, L., Cloetens, L., Herzig, K. H., Hukkanen, J., Rosqvist, F., Ulven, S. M., Gunnarsdóttir, I., Thorsdottir, I., Oresic, M., Poutanen, K. S., Risérus, U., Åkesson, B., & Dragsted, L. O. (2021). Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids. Clinical nutrition (Edinburgh, Scotland), 41(2), 441-451. https://doi.org/10.1016/j.clnu.2021.12.031
Gürdeniz, Gözde, et al. "Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids." Clinical nutrition (Edinburgh, Scotland) vol. 41,2 (2021): 441-451. doi: https://doi.org/10.1016/j.clnu.2021.12.031
Gürdeniz G, Uusitupa M, Hermansen K, Savolainen MJ, Schwab U, Kolehmainen M, Brader L, Cloetens L, Herzig KH, Hukkanen J, Rosqvist F, Ulven SM, Gunnarsdóttir I, Thorsdottir I, Oresic M, Poutanen KS, Risérus U, Åkesson B, Dragsted LO. Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids. Clin Nutr. 2021 Dec 25;41(2):441-451. doi: 10.1016/j.clnu.2021.12.031. Epub 2021 Dec 25. PMID: 35007813.
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The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation.

EMBO reports

El Kharraz S, Dubois V, van Royen ME, Houtsmuller AB, Pavlova E, Atanassova N, Nguyen T, Voet A, Eerlings R, Handle F, Prekovic S, Smeets E, Moris L, Devlies W, Ohlsson C, Poutanen M, Verstrepen KJ, Carmeliet G, Launonen KM, Helminen L, Palvimo JJ, Libert C, Vanderschueren D, Helsen C, Claessens F.
PMID: 34661369
EMBO Rep. 2021 Dec 06;22(12):e52764. doi: 10.15252/embr.202152764. Epub 2021 Oct 18.

Whereas dimerization of the DNA-binding domain of the androgen receptor (AR) plays an evident role in recognizing bipartite response elements, the contribution of the dimerization of the ligand-binding domain (LBD) to the correct functioning of the AR remains unclear....

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El Kharraz S, Dubois V, van Royen ME, et al. The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation. EMBO Rep. 2021;22(12):e52764doi: 10.15252/embr.202152764.
El Kharraz, S., Dubois, V., van Royen, M. E., Houtsmuller, A. B., Pavlova, E., Atanassova, N., Nguyen, T., Voet, A., Eerlings, R., Handle, F., Prekovic, S., Smeets, E., Moris, L., Devlies, W., Ohlsson, C., Poutanen, M., Verstrepen, K. J., Carmeliet, G., Launonen, K. M., Helminen, L., Palvimo, J. J., Libert, C., Vanderschueren, D., Helsen, C., & Claessens, F. (2021). The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation. EMBO reports, 22(12), e52764. https://doi.org/10.15252/embr.202152764
El Kharraz, Sarah, et al. "The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation." EMBO reports vol. 22,12 (2021): e52764. doi: https://doi.org/10.15252/embr.202152764
El Kharraz S, Dubois V, van Royen ME, Houtsmuller AB, Pavlova E, Atanassova N, Nguyen T, Voet A, Eerlings R, Handle F, Prekovic S, Smeets E, Moris L, Devlies W, Ohlsson C, Poutanen M, Verstrepen KJ, Carmeliet G, Launonen KM, Helminen L, Palvimo JJ, Libert C, Vanderschueren D, Helsen C, Claessens F. The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation. EMBO Rep. 2021 Dec 06;22(12):e52764. doi: 10.15252/embr.202152764. Epub 2021 Oct 18. PMID: 34661369; PMCID: PMC8647150.
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Correction: MALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility.

Life science alliance

Lahiri S, Aftab W, Walenta L, Strauss L, Poutanen M, Mayerhofer A, Imhof A.
PMID: 33479050
Life Sci Alliance. 2021 Jan 21;4(3). doi: 10.26508/lsa.202101015. Print 2021 Mar.

No abstract available.

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Lahiri S, Aftab W, Walenta L, et al. Correction: MALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility. Life Sci Alliance. 2021;4(3)doi: 10.26508/lsa.202101015.
Lahiri, S., Aftab, W., Walenta, L., Strauss, L., Poutanen, M., Mayerhofer, A., & Imhof, A. (2021). Correction: MALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility. Life science alliance, 4(3), . https://doi.org/10.26508/lsa.202101015
Lahiri, Shibojyoti, et al. "Correction: MALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility." Life science alliance vol. 4,3 (2021). doi: https://doi.org/10.26508/lsa.202101015
Lahiri S, Aftab W, Walenta L, Strauss L, Poutanen M, Mayerhofer A, Imhof A. Correction: MALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility. Life Sci Alliance. 2021 Jan 21;4(3). doi: 10.26508/lsa.202101015. Print 2021 Mar. PMID: 33479050; PMCID: PMC7918713.
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Comparison of Communication Channels for Large-Scale Type 2 Diabetes Risk Screening and Intervention Recruitment: Empirical Study.

JMIR diabetes

Jalkanen K, Järvenpää R, Tilles-Tirkkonen T, Martikainen J, Aarnio E, Männikkö R, Rantala E, Karhunen L, Kolehmainen M, Harjumaa M, Poutanen K, Ermes M, Absetz P, Schwab U, Lakka T, Pihlajamäki J, Lindström J.
PMID: 34499036
JMIR Diabetes. 2021 Sep 09;6(3):e21356. doi: 10.2196/21356.

BACKGROUND: Clinical trials have shown that type 2 diabetes (T2D) is preventable through lifestyle interventions targeting high-risk people. Nevertheless, large-scale implementation of risk identification followed by preventive interventions has proven to be challenging. Specifically, recruitment of participants into preventive...

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Jalkanen K, Järvenpää R, Tilles-Tirkkonen T, et al. Comparison of Communication Channels for Large-Scale Type 2 Diabetes Risk Screening and Intervention Recruitment: Empirical Study. JMIR Diabetes. 2021;6(3):e21356doi: 10.2196/21356.
Jalkanen, K., Järvenpää, R., Tilles-Tirkkonen, T., Martikainen, J., Aarnio, E., Männikkö, R., Rantala, E., Karhunen, L., Kolehmainen, M., Harjumaa, M., Poutanen, K., Ermes, M., Absetz, P., Schwab, U., Lakka, T., Pihlajamäki, J., Lindström, J. (2021). Comparison of Communication Channels for Large-Scale Type 2 Diabetes Risk Screening and Intervention Recruitment: Empirical Study. JMIR diabetes, 6(3), e21356. https://doi.org/10.2196/21356
Jalkanen, Kari, et al. "Comparison of Communication Channels for Large-Scale Type 2 Diabetes Risk Screening and Intervention Recruitment: Empirical Study." JMIR diabetes vol. 6,3 (2021): e21356. doi: https://doi.org/10.2196/21356
Jalkanen K, Järvenpää R, Tilles-Tirkkonen T, Martikainen J, Aarnio E, Männikkö R, Rantala E, Karhunen L, Kolehmainen M, Harjumaa M, Poutanen K, Ermes M, Absetz P, Schwab U, Lakka T, Pihlajamäki J, Lindström J. Comparison of Communication Channels for Large-Scale Type 2 Diabetes Risk Screening and Intervention Recruitment: Empirical Study. JMIR Diabetes. 2021 Sep 09;6(3):e21356. doi: 10.2196/21356. PMID: 34499036; PMCID: PMC8461532.
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Risk stratification for COVID-19 hospitalization: a multivariable model based on gradient-boosting decision trees.

CMAJ open

Gutierrez JM, Volkovs M, Poutanen T, Watson T, Rosella LC.
PMID: 34933880
CMAJ Open. 2021 Dec 21;9(4):E1223-E1231. doi: 10.9778/cmajo.20210036. Print 2021.

BACKGROUND: The COVID-19 pandemic has led to an increased demand for health care resources and, in some cases, shortage of medical equipment and staff. Our objective was to develop and validate a multivariable model to predict risk of hospitalization...

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Gutierrez JM, Volkovs M, Poutanen T, et al. Risk stratification for COVID-19 hospitalization: a multivariable model based on gradient-boosting decision trees. CMAJ Open. 2021;9(4):E1223-E1231doi: 10.9778/cmajo.20210036.
Gutierrez, J. M., Volkovs, M., Poutanen, T., Watson, T., & Rosella, L. C. (2021). Risk stratification for COVID-19 hospitalization: a multivariable model based on gradient-boosting decision trees. CMAJ open, 9(4), E1223-E1231. https://doi.org/10.9778/cmajo.20210036
Gutierrez, Jahir M, et al. "Risk stratification for COVID-19 hospitalization: a multivariable model based on gradient-boosting decision trees." CMAJ open vol. 9,4 (2021): E1223-E1231. doi: https://doi.org/10.9778/cmajo.20210036
Gutierrez JM, Volkovs M, Poutanen T, Watson T, Rosella LC. Risk stratification for COVID-19 hospitalization: a multivariable model based on gradient-boosting decision trees. CMAJ Open. 2021 Dec 21;9(4):E1223-E1231. doi: 10.9778/cmajo.20210036. Print 2021. PMID: 34933880.
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Development and Validation of a Machine Learning Model Using Administrative Health Data to Predict Onset of Type 2 Diabetes.

JAMA network open

Ravaut M, Harish V, Sadeghi H, Leung KK, Volkovs M, Kornas K, Watson T, Poutanen T, Rosella LC.
PMID: 34032855
JAMA Netw Open. 2021 May 03;4(5):e2111315. doi: 10.1001/jamanetworkopen.2021.11315.

IMPORTANCE: Systems-level barriers to diabetes care could be improved with population health planning tools that accurately discriminate between high- and low-risk groups to guide investments and targeted interventions.OBJECTIVE: To develop and validate a population-level machine learning model for predicting...

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Ravaut M, Harish V, Sadeghi H, et al. Development and Validation of a Machine Learning Model Using Administrative Health Data to Predict Onset of Type 2 Diabetes. JAMA Netw Open. 2021;4(5):e2111315doi: 10.1001/jamanetworkopen.2021.11315.
Ravaut, M., Harish, V., Sadeghi, H., Leung, K. K., Volkovs, M., Kornas, K., Watson, T., Poutanen, T., & Rosella, L. C. (2021). Development and Validation of a Machine Learning Model Using Administrative Health Data to Predict Onset of Type 2 Diabetes. JAMA network open, 4(5), e2111315. https://doi.org/10.1001/jamanetworkopen.2021.11315
Ravaut, Mathieu, et al. "Development and Validation of a Machine Learning Model Using Administrative Health Data to Predict Onset of Type 2 Diabetes." JAMA network open vol. 4,5 (2021): e2111315. doi: https://doi.org/10.1001/jamanetworkopen.2021.11315
Ravaut M, Harish V, Sadeghi H, Leung KK, Volkovs M, Kornas K, Watson T, Poutanen T, Rosella LC. Development and Validation of a Machine Learning Model Using Administrative Health Data to Predict Onset of Type 2 Diabetes. JAMA Netw Open. 2021 May 03;4(5):e2111315. doi: 10.1001/jamanetworkopen.2021.11315. PMID: 34032855; PMCID: PMC8150694.
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The safety and efficacy of fecal microbiota transplantation in a population with bipolar disorder during depressive episodes: study protocol for a pilot randomized controlled trial.

Pilot and feasibility studies

Cooke NCA, Bala A, Allard JP, Hota S, Poutanen S, Taylor VH.
PMID: 34261526
Pilot Feasibility Stud. 2021 Jul 14;7(1):142. doi: 10.1186/s40814-021-00882-4.

BACKGROUND: Bipolar disorder (BD) is a chronic, debilitating illness with significant medical morbidity, often secondary to current treatments, and a high recurrence rate. This burden of disease reflects limitations in the tolerability and efficacy of current treatments. There is...

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Cooke NCA, Bala A, Allard JP, et al. The safety and efficacy of fecal microbiota transplantation in a population with bipolar disorder during depressive episodes: study protocol for a pilot randomized controlled trial. Pilot Feasibility Stud. 2021;7(1):142doi: 10.1186/s40814-021-00882-4.
Cooke, N. C. A., Bala, A., Allard, J. P., Hota, S., Poutanen, S., & Taylor, V. H. (2021). The safety and efficacy of fecal microbiota transplantation in a population with bipolar disorder during depressive episodes: study protocol for a pilot randomized controlled trial. Pilot and feasibility studies, 7(1), 142. https://doi.org/10.1186/s40814-021-00882-4
Cooke, Noah C A, et al. "The safety and efficacy of fecal microbiota transplantation in a population with bipolar disorder during depressive episodes: study protocol for a pilot randomized controlled trial." Pilot and feasibility studies vol. 7,1 (2021): 142. doi: https://doi.org/10.1186/s40814-021-00882-4
Cooke NCA, Bala A, Allard JP, Hota S, Poutanen S, Taylor VH. The safety and efficacy of fecal microbiota transplantation in a population with bipolar disorder during depressive episodes: study protocol for a pilot randomized controlled trial. Pilot Feasibility Stud. 2021 Jul 14;7(1):142. doi: 10.1186/s40814-021-00882-4. PMID: 34261526; PMCID: PMC8278713.
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