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Showing 325 to 336 of 336 entries
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Common variants in breast cancer risk loci predispose to distinct tumor subtypes.

Breast cancer research : BCR

Ahearn TU, Zhang H, Michailidou K, Milne RL, Bolla MK, Dennis J, Dunning AM, Lush M, Wang Q, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Auer PL, Augustinsson A, Baten A, Becher H, Behrens S, Benitez J, Bermisheva M, Blomqvist C, Bojesen SE, Bonanni B, Børresen-Dale AL, Brauch H, Brenner H, Brooks-Wilson A, Brüning T, Burwinkel B, Buys SS, Canzian F, Castelao JE, Chang-Claude J, Chanock SJ, Chenevix-Trench G, Clarke CL, Collée JM, Cox A, Cross SS, Czene K, Daly MB, Devilee P, Dörk T, Dwek M, Eccles DM, Evans DG, Fasching PA, Figueroa J, Floris G, Gago-Dominguez M, Gapstur SM, García-Sáenz JA, Gaudet MM, Giles GG, Goldberg MS, González-Neira A, Alnæs GIG, Grip M, Guénel P, Haiman CA, Hall P, Hamann U, Harkness EF, Heemskerk-Gerritsen BAM, Holleczek B, Hollestelle A, Hooning MJ, Hoover RN, Hopper JL, Howell A, Jakimovska M, Jakubowska A, John EM, Jones ME, Jung A, Kaaks R, Kauppila S, Keeman R, Khusnutdinova E, Kitahara CM, Ko YD, Koutros S, Kristensen VN, Krüger U, Kubelka-Sabit K, Kurian AW, Kyriacou K, Lambrechts D, Lee DG, Lindblom A, Linet M, Lissowska J, Llaneza A, Lo WY, MacInnis RJ, Mannermaa A, Manoochehri M, Margolin S, Martinez ME, McLean C, Meindl A, Menon U, Nevanlinna H, Newman WG, Nodora J, Offit K, Olsson H, Orr N, Park-Simon TW, Patel AV, Peto J, Pita G, Plaseska-Karanfilska D, Prentice R, Punie K, Pylkäs K, Radice P, Rennert G, Romero A, Rüdiger T, Saloustros E, Sampson S, Sandler DP, Sawyer EJ, Schmutzler RK, Schoemaker MJ, Schöttker B, Sherman ME, Shu XO, Smichkoska S, Southey MC, Spinelli JJ, Swerdlow AJ, Tamimi RM, Tapper WJ, Taylor JA, Teras LR, Terry MB, Torres D, Troester MA, Vachon CM, van Deurzen CHM, van Veen EM, Wagner P, Weinberg CR, Wendt C, Wesseling J, Winqvist R, Wolk A, Yang XR, Zheng W, Couch FJ, Simard J, Kraft P, Easton DF, Pharoah PDP, Schmidt MK, García-Closas M, Chatterjee N.
PMID: 34983606
Breast Cancer Res. 2022 Jan 04;24(1):2. doi: 10.1186/s13058-021-01484-x.

BACKGROUND: Genome-wide association studies (GWAS) have identified multiple common breast cancer susceptibility variants. Many of these variants have differential associations by estrogen receptor (ER) status, but how these variants relate with other tumor features and intrinsic molecular subtypes is...

Treating severe asthma: Targeting the IL-5 pathway.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

Principe S, Porsbjerg C, Bolm Ditlev S, Kjaersgaard Klein D, Golebski K, Dyhre-Petersen N, van Dijk YE, van Bragt JJMH, Dankelman LLH, Dahlen SE, Brightling CE, Vijverberg SJH, Maitland-van der Zee AH.
PMID: 33887082
Clin Exp Allergy. 2021 Aug;51(8):992-1005. doi: 10.1111/cea.13885. Epub 2021 May 21.

Severe asthma is a heterogeneous disease with different phenotypes based on clinical, functional or inflammatory parameters. In particular, the eosinophilic phenotype is associated with type 2 inflammation and increased levels of interleukin (IL)-4, IL-5 and IL-13). Monoclonal antibodies that...

Prevalence of peripheral intravenous catheters and policy adherence: A point prevalence in a tertiary care university hospital.

Journal of clinical nursing

Berger S, Winchester K, Principe RB, Culverwell E.
PMID: 34535927
J Clin Nurs. 2021 Sep 17; doi: 10.1111/jocn.16051. Epub 2021 Sep 17.

AIMS AND OBJECTIVES: To determine prevalence and policy adherence for peripheral intravenous catheters (PIVC) in adult inpatients at a tertiary care university hospital (with about 83,000 inpatient admissions annually).BACKGROUND: Up to 80% of hospitalised patients receive intravenous therapy, most...

Development and Internal Validation of a Predictive Model for Adult GH Deficiency Prior to Stimulation Tests.

Frontiers in endocrinology

Bioletto F, Parasiliti-Caprino M, Berton AM, Prencipe N, Cambria V, Ghigo E, Grottoli S, Gasco V.
PMID: 34630332
Front Endocrinol (Lausanne). 2021 Sep 24;12:737947. doi: 10.3389/fendo.2021.737947. eCollection 2021.

BACKGROUND: The diagnosis of adult GH deficiency (GHD) relies on a reduced GH response to provocative tests. Their diagnostic accuracy, however, is not perfect, and a reliable estimation of pre-test GHD probability could be helpful for a better interpretation...

Exhaled Metabolite Patterns to Identify Recent Asthma Exacerbations.

Metabolites

van Bragt JJMH, Principe S, Hashimoto S, Versteeg DN, Brinkman P, Vijverberg SJH, Weersink EJM, Scichilone N, Maitland-van der Zee AH.
PMID: 34940630
Metabolites. 2021 Dec 15;11(12). doi: 10.3390/metabo11120872.

Asthma is a chronic respiratory disease that can lead to exacerbations, defined as acute episodes of worsening respiratory symptoms and lung function. Predicting the occurrence of these exacerbations is an important goal in asthma management. The measurement of exhaled...

STRYDE versus PRECICE magnetic internal lengthening nail for femur lengthening.

Archives of orthopaedic and trauma surgery

Galal S, Shin J, Principe P, Khabyeh-Hasbani N, Mehta R, Hamilton A, Rozbruch SR, Fragomen AT.
PMID: 33983528
Arch Orthop Trauma Surg. 2021 May 13; doi: 10.1007/s00402-021-03943-8. Epub 2021 May 13.

INTRODUCTION: Magnetic internal lengthening nails (MILNs) have been used for femoral lengthening to avoid complications associated with external fixation. The titanium version of the MILN (PRECICEMETHODS: A single-center, retrospective cohort study was conducted in which patients' records were reviewed...

Precise Measurement of the D^{0} and D^{+} Lifetimes at Belle II.

Physical review letters

Abudinén F, Adachi I, Adamczyk K, Aggarwal L, Ahmed H, Aihara H, Akopov N, Aloisio A, Anh Ky N, Asner DM, Atmacan H, Aushev V, Babu V, Bacher S, Bae H, Baehr S, Bahinipati S, Bambade P, Banerjee S, Bansal S, Barrett M, Baudot J, Bauer M, Baur A, Becker J, Behera PK, Bennett JV, Bernieri E, Bernlochner FU, Bertemes M, Bertholet E, Bessner M, Bettarini S, Bhardwaj V, Bianchi F, Bilka T, Bilokin S, Biswas D, Bobrov A, Bodrov D, Bolz A, Bozek A, Bračko M, Branchini P, Braun N, Briere RA, Browder TE, Budano A, Bussino S, Campajola M, Cao L, Casarosa G, Cecchi C, Červenkov D, Chang MC, Chang P, Cheaib R, Chekelian V, Chen C, Chen YT, Cheon BG, Chilikin K, Chirapatpimol K, Cho HE, Cho K, Cho SJ, Choi SK, Choudhury S, Cinabro D, Corona L, Cremaldi LM, Cunliffe S, Czank T, Dattola F, De La Cruz-Burelo E, de Marino G, De Nardo G, De Pietro G, de Sangro R, Destefanis M, Dey S, De Yta-Hernandez A, Di Canto A, Di Capua F, Dingfelder J, Doležal Z, Domínguez Jiménez I, Dong TV, Dorigo M, Dort K, Dossett D, Dubey S, Duell S, Dujany G, Ecker P, Epifanov D, Ferber T, Ferlewicz D, Finocchiaro G, Flood K, Fodor A, Forti F, Fulsom BG, Gabrielli A, Gabyshev N, Gaz A, Gellrich A, Giakoustidis G, Giordano R, Giri A, Glazov A, Gobbo B, Godang R, Goldenzweig P, Golob B, Gradl W, Graziani E, Greenwald D, Gu T, Guan Y, Gudkova K, Guilliams J, Hadjivasiliou C, Halder S, Hara K, Hara T, Hartbrich O, Hayasaka K, Hayashii H, Hazra S, Hearty C, Heredia de la Cruz I, Hernández Villanueva M, Hershenhorn A, Higuchi T, Hill EC, Hirata H, Hoek M, Hohmann M, Hsu CL, Humair T, Iijima T, Inami K, Inguglia G, Ishikawa A, Itoh R, Iwasaki M, Iwasaki Y, Jacobs WW, Jaffe DE, Jang EJ, Jia S, Jin Y, Junkerkalefeld H, Kakuno H, Kaliyar AB, Kandra J, Kang KH, Karl R, Karyan G, Kato Y, Kawasaki T, Kiesling C, Kim CH, Kim DY, Kim YK, Kim Y, Kimmel TD, Kinoshita K, Kodyš P, Koga T, Kohani S, Konno T, Korpar S, Kovalenko E, Kowalewski R, Kraetzschmar TMG, Krinner F, Križan P, Krokovny P, Kuhr T, Kumar J, Kumar M, Kumar R, Kumara K, Kurz S, Kuzmin A, Kwon YJ, Lacaprara S, Lalwani K, Lam T, Lanceri L, Lange JS, Laurenza M, Lautenbach K, Le Diberder FR, Lee SC, Leitl P, Levit D, Li C, Li LK, Libby J, Lieret K, Liptak Z, Liu QY, Liventsev D, Longo S, Lueck T, Lyu C, Manfredi R, Manoni E, Marinas C, Martini A, Matsuda T, Matsuoka K, Matvienko D, McKenna JA, Meier F, Merola M, Metzner F, Miller C, Miyabayashi K, Mizuk R, Mohanty GB, Molina-Gonzalez N, Moon H, Moser HG, Mrvar M, Murphy C, Mussa R, Nakamura I, Nakamura KR, Nakao M, Nakazawa H, Natkaniec Z, Natochii A, Nazaryan G, Niebuhr C, Niiyama M, Nisar NK, Nishida S, Nishimura K, Ogawa S, Onishchuk Y, Ono H, Onuki Y, Oskin P, Oxford ER, Ozaki H, Pakhlov P, Paladino A, Pang T, Panta A, Paoloni E, Pardi S, Park H, Park SH, Paschen B, Passeri A, Pathak A, Patra S, Paul S, Pedlar TK, Peruzzi I, Peschke R, Pestotnik R, Pham F, Piccolo M, Piilonen LE, Pinna Angioni G, Podesta-Lerma PLM, Podobnik T, Pokharel S, Polat G, Popov V, Praz C, Prell S, Prencipe E, Prim MT, Purohit MV, Purwar H, Rad N, Rados P, Raiz S, Reiter S, Remnev M, Ripp-Baudot I, Rizzo G, Rizzuto LB, Robertson SH, Roney JM, Rostomyan A, Rout N, Rozanska M, Sahoo D, Sanders DA, Sandilya S, Sangal A, Santelj L, Sato Y, Savinov V, Scavino B, Schueler J, Schwanda C, Schwartz AJ, Seino Y, Selce A, Senyo K, Serrano J, Sfienti C, Shiu JG, Shwartz B, Sibidanov A, Simon F, Sobie RJ, Soffer A, Sokolov A, Solovieva E, Spataro S, Spruck B, Starič M, Stefkova S, Stottler ZS, Stroili R, Strube J, Sumihama M, Sutcliffe W, Suzuki SY, Svidras H, Tabata M, Takizawa M, Tamponi U, Tanaka S, Tanida K, Tanigawa H, Taniguchi N, Tenchini F, Tiwary R, Tonelli D, Torassa E, Toutounji N, Trabelsi K, Tsuboyama T, Ueda I, Uehara S, Uematsu Y, Uglov T, Unger K, Unno Y, Uno K, Uno S, Urquijo P, Ushiroda Y, Usov YV, Vahsen SE, van Tonder R, Varner GS, Vinokurova A, Vitale L, Vossen A, Waheed E, Wakeling HM, Wang E, Wang MZ, Wang XL, Warburton A, Watanabe M, Welsch M, Wessel C, Wiechczynski J, Won E, Xu XP, Yabsley BD, Yamada S, Yan W, Yang SB, Ye H, Yelton J, Yin JH, Yoshihara K, Yusa Y, Zani L, Zhilich V, Zhou QD, Zhou XY, Zhukova VI, Žlebčík R.
PMID: 34860075
Phys Rev Lett. 2021 Nov 19;127(21):211801. doi: 10.1103/PhysRevLett.127.211801.

We report a measurement of the D^{0} and D^{+} lifetimes using D^{0}→K^{-}π^{+} and D^{+}→K^{-}π^{+}π^{+} decays reconstructed in e^{+}e^{-}→cc[over ¯] data recorded by the Belle II experiment at the SuperKEKB asymmetric-energy e^{+}e^{-} collider. The data, collected at center-of-mass energies at...

Multichannel Electrocardiograms Obtained by a Smartwatch for the Diagnosis of ST-Segment Changes.

JAMA cardiology

Spaccarotella CAM, Polimeni A, Migliarino S, Principe E, Curcio A, Mongiardo A, Sorrentino S, De Rosa S, Indolfi C.
PMID: 32865545
JAMA Cardiol. 2020 Oct 01;5(10):1176-1180. doi: 10.1001/jamacardio.2020.3994.

IMPORTANCE: Acute coronary syndromes are the leading cause of death worldwide and the leading cause of disease burden in high-income countries. Quick and accurate diagnosis of acute coronary syndromes is essential to avoid fatal events, for timely intervention, and...

Clinical Characteristics, Treatment and Evolution of Splenic and Nodal Marginal Zone Lymphomas-Retrospective and Multicentric Analysis of Portuguese Centers.

Clinical lymphoma, myeloma & leukemia

Rodrigues CD, Peixeiro RP, Viegas D, Chorão P, Couto ME, Gaspar CL, Fernandes JP, Alves D, Ribeiro LA, de Vasconcelos M P, Tomé AL, Badior M, Coelho H, Príncipe F, Chacim S, da Silva MG, Coutinho R.
PMID: 34326035
Clin Lymphoma Myeloma Leuk. 2021 Nov;21(11):e839-e844. doi: 10.1016/j.clml.2021.06.013. Epub 2021 Jun 24.

INTRODUCTION: Treatment of Splenic (SMZL) and Nodal (NMZL) Marginal Zone Lymphoma is not consensual. Histologic transformation (HT) to aggressive lymphoma is a poorly understood event, with an unfavorable outcome.OBJECTIVES: Describe the clinical characteristics, treatment, outcomes and incidence of HT.METHODS:...

Humerus Lengthening: A Comparison of the Internal Lengthening Nail to External Fixation.

HSS journal : the musculoskeletal journal of Hospital for Special Surgery

Galal S, Shin J, Principe P, Mehta R, Khabyeh-Hasbani N, Hamilton A, Fragomen A, Rozbruch SR.
PMID: 34421432
HSS J. 2021 Jul;17(2):207-212. doi: 10.1177/1556331621996334. Epub 2021 Mar 04.

No abstract available.

LRP1B: A Giant Lost in Cancer Translation.

Pharmaceuticals (Basel, Switzerland)

Príncipe C, Dionísio de Sousa IJ, Prazeres H, Soares P, Lima RT.
PMID: 34577535
Pharmaceuticals (Basel). 2021 Aug 24;14(9). doi: 10.3390/ph14090836.

Low-density lipoprotein receptor-related protein 1B (LRP1B) is a giant member of the LDLR protein family, which includes several structurally homologous cell surface receptors with a wide range of biological functions from cargo transport to cell signaling. LRP1B is among...

MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3.

Oncogene

Singh SK, Kumar S, Viswakarma N, Principe DR, Das S, Sondarva G, Nair RS, Srivastava P, Sinha SC, Grippo PJ, Thatcher GRJ, Rana B, Rana A.
PMID: 34511598
Oncogene. 2021 Oct;40(43):6153-6165. doi: 10.1038/s41388-021-02007-w. Epub 2021 Sep 13.

MAP4K4 is a Ste20 member and reported to play important roles in various pathologies, including in cancer. However, the mechanism by which MAP4K4 promotes pancreatic cancer is not fully understood. It is suggested that MAP4K4 might function as a...

Showing 325 to 336 of 336 entries