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Showing 13 to 24 of 268 entries
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The Regulation of the Small Heat Shock Protein B8 in Misfolding Protein Diseases Causing Motoneuronal and Muscle Cell Death.

Frontiers in neuroscience

Cristofani R, Rusmini P, Galbiati M, Cicardi ME, Ferrari V, Tedesco B, Casarotto E, Chierichetti M, Messi E, Piccolella M, Carra S, Crippa V, Poletti A.
PMID: 31427919
Front Neurosci. 2019 Aug 02;13:796. doi: 10.3389/fnins.2019.00796. eCollection 2019.

Misfolding protein diseases are a wide class of disorders in which the aberrantly folded protein aggregates accumulate in affected cells. In the brain and in the skeletal muscle, misfolded protein accumulation induces a variety of cell dysfunctions that frequently...

Flow reproducibility of whole blood and other bodily fluids in simplified no reaction lateral flow assay devices.

Biomicrofluidics

Li H, Han D, Hegener MA, Pauletti GM, Steckl AJ.
PMID: 28798852
Biomicrofluidics. 2017 Apr 07;11(2):024116. doi: 10.1063/1.4979815. eCollection 2017 Mar.

The "no reaction" lateral flow assay (nrLFA) uses a simplified LFA structure with no conjugate pad and no stored reagents. In the nrLFA, the capillary-based transport time or distance is the key indicator, rather than the outcome of a...

Percutaneous closure of aortic and mitral paravalvular leak with the Occlutech™ PL Device - Report of the first cases in Mexico.

Archivos de cardiologia de Mexico

Jiménez-Valverde AS, Escutia-Cuevas HH, Aceves-Millán R, Fuentes-Espinoza PM, Pérez-Siller G, Espinoza-Rueda MA.
PMID: 30932092
Arch Cardiol Mex. 2019;89(1):88-91. doi: 10.24875/ACM.M19000008.

No abstract available.

Effective treatment of a platinum-resistant cutaneous squamous cell carcinoma case by EGFR pathway inhibition.

Molecular and clinical oncology

Capalbo C, Belardinilli F, Filetti M, Parisi C, Petroni M, Colicchia V, Tessitore A, Santoni M, Coppa A, Giannini G, Marchetti P, Needham DM.
PMID: 29977536
Mol Clin Oncol. 2018 Jul;9(1):30-34. doi: 10.3892/mco.2018.1634. Epub 2018 May 21.

Cutaneous squamous cell carcinoma (cSCC) is the second most common type of non-melanoma skin cancer. Platinum-based regimens have been an integral part of palliative care for patients with locally advanced or metastatic disease. There is no evidence of efficacy...

Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines.

Frontiers in oncology

Fumarola C, Bozza N, Castelli R, Ferlenghi F, Marseglia G, Lodola A, Bonelli M, La Monica S, Cretella D, Alfieri R, Minari R, Galetti M, Tiseo M, Ardizzoni A, Mor M, Petronini PG.
PMID: 30972293
Front Oncol. 2019 Mar 26;9:179. doi: 10.3389/fonc.2019.00179. eCollection 2019.

Fibroblast Growth Factor Receptors (FGFR1-4) have a critical role in the progression of several human cancers, including Squamous Non-Small-Cell Lung Cancer (SQCLC). Both non-selective and selective reversible FGFR inhibitors are under clinical investigation for the treatment of patients with...

EMT-Associated Heterogeneity in Circulating Tumor Cells: Sticky Friends on the Road to Metastasis.

Cancers

Genna A, Vanwynsberghe AM, Villard AV, Pottier C, Ancel J, Polette M, Gilles C.
PMID: 32575608
Cancers (Basel). 2020 Jun 19;12(6). doi: 10.3390/cancers12061632.

Epithelial-mesenchymal transitions (EMTs) generate hybrid phenotypes with an enhanced ability to adapt to diverse microenvironments encountered during the metastatic spread. Accordingly, EMTs play a crucial role in the biology of circulating tumor cells (CTCs) and contribute to their heterogeneity....

Genomic analysis of .

Communications biology

Pauletto M, Manousaki T, Ferraresso S, Babbucci M, Tsakogiannis A, Louro B, Vitulo N, Quoc VH, Carraro R, Bertotto D, Franch R, Maroso F, Aslam ML, Sonesson AK, Simionati B, Malacrida G, Cestaro A, Caberlotto S, Sarropoulou E, Mylonas CC, Power DM, Patarnello T, Canario AVM, Tsigenopoulos C, Bargelloni L.
PMID: 30271999
Commun Biol. 2018 Aug 17;1:119. doi: 10.1038/s42003-018-0122-7. eCollection 2018.

Sexual dimorphism is a fascinating subject in evolutionary biology and mostly results from sex-biased expression of genes, which have been shown to evolve faster in gonochoristic species. We report here genome and sex-specific transcriptome sequencing of

Usefulness of sleep events detection using a wrist worn peripheral arterial tone signal device (WatchPAT™) in a population at low risk of obstructive sleep apnea.

Journal of sleep research

Tondo P, Drigo R, Scioscia G, Ballarin A, Rossi E, Floriani AF, Pauletti A, Foschino Barbaro MP, Lacedonia D.
PMID: 33845515
J Sleep Res. 2021 Dec;30(6):e13352. doi: 10.1111/jsr.13352. Epub 2021 Apr 12.

Due to the high prevalence of obstructive sleep apnea (OSA), it is recommended to use in-laboratory polysomnography (PSG) or a home sleep apnea test (HSAT) in uncomplicated adult subjects at high risk of OSA. The aims of the present...

Aqueous suspensions of Fuller's earth potentiate the adsorption capacities of paraoxon and improve skin decontamination properties.

Journal of hazardous materials

Danoy A, Durmaz K, Paoletti M, Vachez L, Roul A, Sohier J, Verrier B.
PMID: 34896712
J Hazard Mater. 2021 Nov 12;425:127714. doi: 10.1016/j.jhazmat.2021.127714. Epub 2021 Nov 12.

Fuller's earth (FE) is a phyllosilicate used as a powder for household or skin decontamination due to its adsorbent properties. Recent studies have shown that water suspensions exhibit similar adsorbent capacities. FE is heterogeneous due to its composition of...

Technical description of a novel device for external ventricular drainage in neonatal and pediatric patients: Results from a single referral center experience.

Clinical neurology and neurosurgery

Consales A, Di Perna G, De Angelis LC, Pacetti M, Balestrino A, Ravegnani M, Pavanello M, Secci F, Ramenghi LA, Piatelli G, Cama A.
PMID: 34973652
Clin Neurol Neurosurg. 2021 Dec 21;213:107100. doi: 10.1016/j.clineuro.2021.107100. Epub 2021 Dec 21.

BACKGROUND: Since external ventricular drainage (EVD) related infections are usually due to skin flora, an extradural intra/extra-cranial accessory device, developed for pediatric patients under three years of age undergoing EVD positioning, is described. The aim of this paper is...

Subjective experience of aberrant salience in young people at Ultra-High Risk (UHR) for psychosis: a cross-sectional study.

Nordic journal of psychiatry

Poletti M, Pelizza L, Azzali S, Garlassi S, Scazza I, Paterlini F, Chiri LR, Pupo S, Raballo A.
PMID: 34185607
Nord J Psychiatry. 2021 Jun 29;1-9. doi: 10.1080/08039488.2021.1942547. Epub 2021 Jun 29.

PURPOSE: Aberrant salience (AS) is conceptualized as a potential predisposing factor for psychotic states of mind. Despite several studies in the general population, research on AS in the early phases of psychosis is still relatively scarce. The aim of...

Plating human iPSC lines on micropatterned substrates reveals role for ITGB1 nsSNV in endoderm formation.

Stem cell reports

Vickers A, Tewary M, Laddach A, Poletti M, Salameti V, Fraternali F, Danovi D, Watt FM.
PMID: 34678211
Stem Cell Reports. 2021 Nov 09;16(11):2628-2641. doi: 10.1016/j.stemcr.2021.09.017. Epub 2021 Oct 21.

Quantitative analysis of human induced pluripotent stem cell (iPSC) lines from healthy donors is a powerful tool for uncovering the relationship between genetic variants and cellular behavior. We previously identified rare, deleterious non-synonymous single nucleotide variants (nsSNVs) in cell...

Showing 13 to 24 of 268 entries