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Showing 13 to 24 of 38 entries
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Neuron-Glia Crosstalk in the Autonomic Nervous System and Its Possible Role in the Progression of Metabolic Syndrome: A New Hypothesis.

Frontiers in physiology

Del Rio R, Quintanilla RA, Orellana JA, Retamal MA.
PMID: 26648871
Front Physiol. 2015 Dec 01;6:350. doi: 10.3389/fphys.2015.00350. eCollection 2015.

Metabolic syndrome (MS) is characterized by the following physiological alterations: increase in abdominal fat, insulin resistance, high concentration of triglycerides, low levels of HDL, high blood pressure, and a generalized inflammatory state. One of the pathophysiological hallmarks of this...

Role of PPAR γ in the Differentiation and Function of Neurons.

PPAR research

Quintanilla RA, Utreras E, Cabezas-Opazo FA.
PMID: 25246934
PPAR Res. 2014;2014:768594. doi: 10.1155/2014/768594. Epub 2014 Aug 26.

Neuronal processes (neurites and axons) have an important role in brain cells communication and, generally, they are damaged in neurodegenerative diseases. Recent evidence has showed that the activation of PPARγ pathway promoted neuronal differentiation and axon polarity. In addition,...

Truncated Tau Induces Mitochondrial Transport Failure Through the Impairment of TRAK2 Protein and Bioenergetics Decline in Neuronal Cells.

Frontiers in cellular neuroscience

Quintanilla RA, Tapia-Monsalves C, Vergara EH, Pérez MJ, Aranguiz A.
PMID: 32848607
Front Cell Neurosci. 2020 Jul 30;14:175. doi: 10.3389/fncel.2020.00175. eCollection 2020.

Mitochondria are highly specialized organelles essential for the synapse, and their impairment contributes to the neurodegeneration in Alzheimer's disease (AD). Previously, we studied the role of caspase-3-cleaved tau in mitochondrial dysfunction in AD. In neurons, the presence of this...

Ventilatory and Autonomic Regulation in Sleep Apnea Syndrome: A Potential Protective Role for Erythropoietin?.

Frontiers in physiology

Andrade DC, Haine L, Toledo C, Diaz HS, Quintanilla RA, Marcus NJ, Iturriaga R, Richalet JP, Voituron N, Del Rio R.
PMID: 30374309
Front Physiol. 2018 Oct 16;9:1440. doi: 10.3389/fphys.2018.01440. eCollection 2018.

Obstructive sleep apnea (OSA) is the most common form of sleep disordered breathing and is associated with wide array of cardiovascular morbidities. It has been proposed that during OSA, the respiratory control center (RCC) is affected by exaggerated afferent...

3D-Printed Fe/γ-Al.

ACS applied materials & interfaces

Salazar-Aguilar AD, Quintanilla A, López P, Martínez C, Vega-Díaz SM, Casas JA, Miranzo P, Osendi MI, Belmonte M.
PMID: 34939422
ACS Appl Mater Interfaces. 2022 Jan 12;14(1):920-932. doi: 10.1021/acsami.1c19755. Epub 2021 Dec 23.

The synthesis of dihydroxybenzenes (DHBZ), essential chemical reagents in numerous industrial processes, with a high degree of selectivity and yield from the hydroxylation of phenol is progressively attracting great interest in the catalysis field. Furthermore, the additive manufacturing of...

Nanofluidization electrostatics.

Physical review. E, Statistical, nonlinear, and soft matter physics

Valverde JM, Quintanilla MA, Espin MJ, Castellanos A.
PMID: 18517364
Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Mar;77(3):031301. doi: 10.1103/PhysRevE.77.031301. Epub 2008 Mar 12.

Electrostatic charging of powders is a relevant phenomenon for a number of industrial applications. The design of new processes and the use of high resistivity materials and ultrafine powders may lead to higher charging rates and to higher levels...

Tau Deletion Prevents Cognitive Impairment and Mitochondrial Dysfunction Age Associated by a Mechanism Dependent on Cyclophilin-D.

Frontiers in neuroscience

Jara C, Cerpa W, Tapia-Rojas C, Quintanilla RA.
PMID: 33679286
Front Neurosci. 2021 Feb 10;14:586710. doi: 10.3389/fnins.2020.586710. eCollection 2020.

Aging is an irreversible process and the primary risk factor for the development of neurodegenerative diseases, such as Alzheimer's disease (AD). Mitochondrial impairment is a process that generates oxidative damage and ATP deficit; both factors are important in the...

Looking for self-organized critical behavior in avalanches of slightly cohesive powders.

Physical review letters

Quintanilla MA, Valverde JM, Castellanos A, Viturro RE.
PMID: 11690413
Phys Rev Lett. 2001 Nov 05;87(19):194301. doi: 10.1103/PhysRevLett.87.194301. Epub 2001 Oct 18.

We report results from a statistical analysis of avalanches of cohesive powders in a slowly rotated drum. Interparticle adhesion, which diminishes the effect of inertia and whose magnitude strongly fluctuates in a local scale, makes avalanches in slightly cohesive...

Physics of compaction of fine cohesive particles.

Physical review letters

Castellanos A, Valverde JM, Quintanilla MA.
PMID: 15783824
Phys Rev Lett. 2005 Feb 25;94(7):075501. doi: 10.1103/PhysRevLett.94.075501. Epub 2005 Feb 22.

Fluidized fractal clusters of fine particles display critical-like dynamics at the jamming transition, characterized by a power law relating consolidation stress with volume fraction increment [sigma--(c) proportional, variant(Deltaphi)(beta)]. At a critical stress clusters are disrupted and there is a...

Asymmetry in the percolation thresholds of fully penetrable disks with two different radii.

Physical review. E, Statistical, nonlinear, and soft matter physics

Quintanilla JA, Ziff RM.
PMID: 18233631
Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Nov;76(5):051115. doi: 10.1103/PhysRevE.76.051115. Epub 2007 Nov 14.

We perform simulations of continuum gradient percolation to measure the percolation threshold of systems of fully penetrable disks of two different radii. As a function of volumetric proportion v, the percolation threshold phic(v,lambda) is approximately symmetric about v=0.5 for...

The Medical Bookshelf.

Postgraduate medicine

Olness K, Taylor RB, Simonds JF, Gormican A, Quintanilla AP, Provisor A, Nolan EJ, Keys TE.
PMID: 27452690
Postgrad Med. 1980 Nov;68(5):240-2. doi: 10.1080/00325481.1980.11715607.

No abstract available.

Fine cohesive powders in rotating drums: Transition from rigid-plastic flow to gas-fluidized regime.

Physical review. E, Statistical, nonlinear, and soft matter physics

Castellanos A, Valverde JM, Quintanilla MA.
PMID: 12188710
Phys Rev E Stat Nonlin Soft Matter Phys. 2002 Jun;65(6):061301. doi: 10.1103/PhysRevE.65.061301. Epub 2002 Jun 12.

We investigate the dynamics of fine cohesive powders inside rotating drums. We show that these powders may be fluidized due to entrapment of ambient gas, and we determine the onset of fluidization. Experimental measurements on the bed expansion as...

Showing 13 to 24 of 38 entries