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Showing 25 to 36 of 383 entries
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Quantifying TOLNet Ozone Lidar Accuracy during the 2014 DISCOVER-AQ and FRAPPÉ Campaigns.

Atmospheric measurement techniques

Wang L, Newchurch MJ, Alvarez RJ, Berkoff TA, Brown SS, Carrion W, De Young RJ, Johnson BJ, Ganoe R, Gronoff G, Kirgis G, Kuang S, Langford AO, Leblanc T, McDuffie EE, McGee TJ, Pliutau D, Senff CJ, Sullivan JT, Sumnicht G, Twigg LW, Weinheimer AJ.
PMID: 32742525
Atmos Meas Tech. 2017 Oct 04;10(10):3865-3876. doi: 10.5194/amt-10-3865-2017. Epub 2017 Oct 23.

The Tropospheric Ozone Lidar Network (TOLNet) is a unique network of lidar systems that measure high-resolution atmospheric profiles of ozone. The accurate characterization of these lidars is necessary to determine the uniformity of cross-instrument calibration. From July to August...

ATP is an essential autocrine factor for pancreatic β-cell signaling and insulin secretion.

Physiological reports

Hauke S, Rada J, Tihanyi G, Schilling D, Schultz C.
PMID: 35001557
Physiol Rep. 2022 Jan;10(1):e15159. doi: 10.14814/phy2.15159.

ATP has been previously identified as an autocrine signaling factor that is co-released with insulin to modulate and propagate β-cell activity within islets of Langerhans. Here, we show that β-cell activity and insulin secretion essentially rely on the presence...

Overview of Causality Assessment for Drug-Induced Liver Injury (DILI) in Clinical Trials.

Drug safety

Hey-Hadavi J, Seekins D, Palmer M, Coffey D, Caminis J, Abdullaev S, Patwardhan M, Tyler H, Raheja R, Stanley AM, Pineda-Salgado L, Bourdet DL, Andrade RJ, Hayashi PH, Dimick-Santos L, Rockey DC, Estilo A.
PMID: 33725335
Drug Saf. 2021 Jun;44(6):619-634. doi: 10.1007/s40264-021-01051-5. Epub 2021 Mar 16.

Causality assessment for suspected drug-induced liver injury (DILI) during drug development and following approval is challenging. The IQ DILI Causality Working Group (CWG), in collaboration with academic and regulatory subject matter experts (SMEs), developed this manuscript with the following...

SARS-CoV-2 Acquisition and Immune Pathogenesis Among School-Aged Learners in Four Diverse Schools.

medRxiv : the preprint server for health sciences

Cooper DM, Zulu MZ, Jankeel A, Ibraim IC, Ardo J, Kasper K, Stephens D, Meyer A, Stehli A, Condon C, Londoño ME, Schreiber CM, Lopez NV, Camplain RL, Weiss M, Golden C, Aizik S, Boden-Albala B, Chau C, Messaoudi I, Ulloa ER.
PMID: 33791712
medRxiv. 2021 Jun 16; doi: 10.1101/2021.03.20.21254035.

BACKGROUND: Understanding SARS-CoV-2 infection in children is necessary to reopen schools safely.METHODS: We measured SARS-CoV-2 infection in 320 learners [10.5 ± 2.1(sd); 7-17 y.o.] at four diverse schools with either remote or on-site learning. Schools A and B served...

Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction.

Acta pharmaceutica Sinica. B

Segovia-Zafra A, Di Zeo-Sánchez DE, López-Gómez C, Pérez-Valdés Z, García-Fuentes E, Andrade RJ, Lucena MI, Villanueva-Paz M.
PMID: 35024301
Acta Pharm Sin B. 2021 Dec;11(12):3685-3726. doi: 10.1016/j.apsb.2021.11.013. Epub 2021 Nov 18.

Idiosyncratic drug-induced liver injury (iDILI) encompasses the unexpected harms that prescription and non-prescription drugs, herbal and dietary supplements can cause to the liver. iDILI remains a major public health problem and a major cause of drug attrition. Given the...

Accidental Dural Tears in Minimally Invasive Spinal Surgery for Degenerative Lumbar Spine Disease.

Frontiers in surgery

Aspalter S, Senker W, Radl C, Aichholzer M, Aufschnaiter-Hießböck K, Leitner C, Stroh N, Trutschnig W, Gruber A, Stefanits H.
PMID: 34355019
Front Surg. 2021 Jul 20;8:708243. doi: 10.3389/fsurg.2021.708243. eCollection 2021.

No abstract available.

Particle-Scale Modeling to Understand Liquid Distribution in Twin-Screw Wet Granulation.

Pharmaceutics

Kumar A, Radl S, Gernaey KV, De Beer T, Nopens I.
PMID: 34206609
Pharmaceutics. 2021 Jun 22;13(7). doi: 10.3390/pharmaceutics13070928.

Experimental characterization of solid-liquid mixing for a high shear wet granulation process in a twin-screw granulator (TSG) is very challenging. This is due to the opacity of the multiphase system and high-speed processing. In this study, discrete element method...

SARS-CoV-2 acquisition and immune pathogenesis among school-aged learners in four diverse schools.

Pediatric research

Cooper DM, Zulu MZ, Jankeel A, Ibraim IC, Ardo J, Kasper K, Stephens D, Meyer A, Stehli A, Condon C, Londoño ME, Schreiber CM, Lopez NV, Camplain RL, Weiss M, Golden C, Radom-Aizik S, Boden-Albala B, Chau C, Messaoudi I, Ulloa ER.
PMID: 34304252
Pediatr Res. 2021 Nov;90(5):1073-1080. doi: 10.1038/s41390-021-01660-x. Epub 2021 Jul 24.

BACKGROUND: Understanding SARS-CoV-2 infection in children is necessary to reopen schools safely.METHODS: We measured SARS-CoV-2 infection in 320 learners [10.5 ± 2.1 (sd); 7-17 y.o.] at four diverse schools with either remote or on-site learning. Schools A and B...

Trends in Utilization and Outcomes of Orbital, Laser, and Excisional Atherectomy for Lower Extremity Revascularization.

Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists

Bai H, Fereydooni A, Zhang Y, Tonnessen BH, Guzman RJ, Chaar CIO.
PMID: 34643142
J Endovasc Ther. 2021 Oct 13;15266028211050329. doi: 10.1177/15266028211050329. Epub 2021 Oct 13.

PURPOSE: The aim of this study is to analyze the utilization pattern of atherectomy modalities and compare their outcomes.MATERIALS AND METHODS: All patients undergoing atherectomy in the 2010-2016 Vascular Quality Initiative Database were identified. Utilization of orbital, laser, or...

Late presentation of chronic HBV and HCV patients seeking first time specialist care in Spain: a 2-year registry review.

Scientific reports

Picchio CA, Lens S, Hernandez-Guerra M, Arenas J, Andrade RJ, Crespo J, García-Samaniego J, Romero-Gómez M, Turnes J, Calleja JL, Simón MÁ, White TM, Riveiro-Barciela M, Pocurull A, Morales-Arraez D, Gómez A, Buti M, Lazarus JV.
PMID: 34921156
Sci Rep. 2021 Dec 17;11(1):24133. doi: 10.1038/s41598-021-01885-0.

Chronic viral hepatitis infection affects an estimated 325 million people globally. People who initiate treatment after significant disease progression face increased risk of severe liver complications and death. Data are scarce on the characteristics and risk factors of people...

Potential beneficial effects of bariatric surgery on the prevalence of kidney cancer: a national database study.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

Botero-Fonnegra C, Funes DR, Valera RJ, Gómez CO, Lo Menzo E, Szomstein S, Rosenthal RJ.
PMID: 34565684
Surg Obes Relat Dis. 2021 Aug 26; doi: 10.1016/j.soard.2021.08.012. Epub 2021 Aug 26.

BACKGROUND: The incidence of obesity has been steadily increasing, especially in developed countries. Also, obesity is considered one of the modifiable risk factors of kidney cancer.OBJECTIVES: This study aims to determine the impact of bariatric surgery-induced weight loss on...

Codesign of a cardiovascular disease prevention text message bank for older adults.

Patient education and counseling

Ardo J, Lee JA, Hildebrand JA, Guijarro D, Ghasemazadeh H, Strömberg A, Evangelista LS.
PMID: 33863587
Patient Educ Couns. 2021 Nov;104(11):2772-2784. doi: 10.1016/j.pec.2021.03.036. Epub 2021 Apr 01.

OBJECTIVE: Develop and validate a text message bank to support healthier lifestyle behaviors in older adults at risk for cardiovascular disease utilizing a codesign approach.METHODS: Initially, the researchers, based on literature, developed a bank of 68 SMS text messages...

Showing 25 to 36 of 383 entries