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Showing 25 to 36 of 71 entries
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Concurrence of sleep problems and distress: prevalence and determinants in parents of children with cancer.

European journal of psychotraumatology

Rensen N, Steur LMH, Schepers SA, Merks JHM, Moll AC, Grootenhuis MA, Kaspers GJL, van Litsenburg RRL.
PMID: 31448065
Eur J Psychotraumatol. 2019 Jul 22;10(1):1639312. doi: 10.1080/20008198.2019.1639312. eCollection 2019.

No abstract available.

Omega-6 and omega-3 oxylipins as potential markers of cardiometabolic risk in young adults.

Obesity (Silver Spring, Md.)

Jurado-Fasoli L, Di X, Kohler I, Osuna-Prieto FJ, Hankemeier T, Krekels E, Harms AC, Yang W, Garcia-Lario JV, Fernández-Veledo S, Ruiz JR, Rensen PCN, Martinez-Tellez B.
PMID: 34898010
Obesity (Silver Spring). 2022 Jan;30(1):50-61. doi: 10.1002/oby.23282. Epub 2021 Dec 12.

OBJECTIVE: Omega-6 and omega-3 oxylipins are known to play a role in inflammation and cardiometabolic diseases in preclinical models. The associations between plasma levels of omega-6 and omega-3 polyunsaturated fatty acid-derived oxylipins and body composition and cardiometabolic risk factors...

A simplified procedure to trace triglyceride-rich lipoprotein metabolism in vivo.

Physiological reports

Ying Z, Boon MR, Coskun T, Kooijman S, Rensen PCN.
PMID: 33945228
Physiol Rep. 2021 Apr;9(8):e14820. doi: 10.14814/phy2.14820.

Glycerol tri[

Plasma ceramides containing saturated fatty acids are associated with risk of type 2 diabetes.

Journal of lipid research

Fretts AM, Jensen PN, Hoofnagle AN, McKnight B, Howard BV, Umans J, Sitlani CM, Siscovick DS, King IB, Djousse L, Sotoodehnia N, Lemaitre RN.
PMID: 34555371
J Lipid Res. 2021;62:100119. doi: 10.1016/j.jlr.2021.100119. Epub 2021 Sep 20.

Recent studies suggest that the type of saturated fatty acid bound to sphingolipids influences the biological activity of those sphingolipids. However, it is unknown whether associations of sphingolipids with diabetes may differ by the identity of bound lipid species....

Subgroup Classification of Myasthenia Gravis.

Annals of Indian Academy of Neurology

Renjen PN.
PMID: 34220098
Ann Indian Acad Neurol. 2021 Mar-Apr;24(2):300. doi: 10.4103/aian.AIAN_237_20. Epub 2020 Jun 05.

No abstract available.

Management of Dyslipidaemia for the Prevention of Stroke: Clinical Practice Recommendations from the Lipid Association of India.

Current vascular pharmacology

Puri R, Mehta V, Iyengar SS, Srivastava P, Yusuf J, Pradhan A, Pandian JD, Sharma VK, Renjen PN, Muruganathan A, Mugundhan K, Srinivasan AV, Shetty S, Narasingan SN, Nair DR, Bansal M, Prabhakar D, Varma M, Paliwal VK, Kapoor A, Mukhopadhyay S, Mehrotra R, Patanwala RM, Aggarwal R, Mahajan K, Kumar S, Bardoloi N, Pareek KK, Manoria PC, Pancholia AK, Nanda R, Wong ND, Duell PB.
PMID: 34751121
Curr Vasc Pharmacol. 2021 Nov 09; doi: 10.2174/1570161119666211109122231. Epub 2021 Nov 09.

Stroke is the second most common cause of death worldwide. The rates of stroke are increasing in less affluent countries predominantly because of a high prevalence of modifiable risk factors. The Lipid Association of India (LAI) has provided a...

Pharmacological treatment with FGF21 strongly improves plasma cholesterol metabolism to reduce atherosclerosis.

Cardiovascular research

Liu C, Schönke M, Zhou E, Li Z, Kooijman S, Boon MR, Larsson M, Wallenius K, Dekker N, Barlind L, Peng XR, Wang Y, Rensen PCN.
PMID: 33693480
Cardiovasc Res. 2021 Mar 08; doi: 10.1093/cvr/cvab076. Epub 2021 Mar 08.

AIMS: Fibroblast growth factor (FGF) 21, a key regulator of energy metabolism, is currently evaluated in humans for treatment of type 2 diabetes and nonalcoholic steatohepatitis. However, the effects of FGF21 on cardiovascular benefit, particularly on lipoprotein metabolism in...

Exploring nicotinamide cofactor promiscuity in NAD(P)H-dependent flavin containing monooxygenases (FMOs) using natural variation within the phosphate binding loop. Structure and activity of FMOs from .

Journal of molecular catalysis. B, Enzymatic

Jensen CN, Ali ST, Allen MJ, Grogan G.
PMID: 25383040
J Mol Catal B Enzym. 2014 Nov;109:191-198. doi: 10.1016/j.molcatb.2014.08.019.

Flavin-containing monooxygenases (FMOs) catalyse asymmetric oxidation reactions that have potential for preparative organic synthesis, but most use the more expensive, phosphorylated nicotinamide cofactor NADPH to reduce FAD to FADH

Microglia-specific knock-down of Bmal1 improves memory and protects mice from high fat diet-induced obesity.

Molecular psychiatry

Wang XL, Kooijman S, Gao Y, Tzeplaeff L, Cosquer B, Milanova I, Wolff SEC, Korpel N, Champy MF, Petit-Demoulière B, Goncalves Da Cruz I, Sorg-Guss T, Rensen PCN, Cassel JC, Kalsbeek A, Boutillier AL, Yi CX.
PMID: 34050326
Mol Psychiatry. 2021 Nov;26(11):6336-6349. doi: 10.1038/s41380-021-01169-z. Epub 2021 May 28.

Microglia play a critical role in maintaining neural function. While microglial activity follows a circadian rhythm, it is not clear how this intrinsic clock relates to their function, especially in stimulated conditions such as in the control of systemic...

Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis.

Circulation

Trinder M, Wang Y, Madsen CM, Ponomarev T, Bohunek L, Daisely BA, Julia Kong H, Blauw LL, Nordestgaard BG, Tybjærg-Hansen A, Wurfel MM, Russell JA, Walley KR, Rensen PCN, Boyd JH, Brunham LR.
PMID: 33228395
Circulation. 2021 Mar 02;143(9):921-934. doi: 10.1161/CIRCULATIONAHA.120.048568. Epub 2020 Nov 24.

BACKGROUND: The high-density lipoprotein hypothesis of atherosclerosis has been challenged by clinical trials of cholesteryl ester transfer protein (CETP) inhibitors, which failed to show significant reductions in cardiovascular events. Plasma levels of high-density lipoprotein cholesterol (HDL-C) decline drastically during...

Plasma Ceramides containing Saturated Fatty Acids are Associated with Risk of Type 2 Diabetes.

Journal of lipid research

Fretts AM, Jensen PN, Hoofnagle AN, McKnight B, Howard BV, Umans J, Sitlani CM, Siscovick DS, King IB, Djousse L, Sotoodehnia N, Lemaitre RN.
PMID: 34555371
J Lipid Res. 2021 Sep 20;100119. doi: 10.1016/j.jlr.2021.100119. Epub 2021 Sep 20.

Recent studies suggest that the type of saturated fatty acid bound to sphingolipids influences the biological activity of those sphingolipids. However, it is unknown whether associations of sphingolipids with diabetes may differ by the identity of bound lipid species....

A hierarchical dynamic model used for investigating feed efficiency and its relationship with hepatic gene expression in APOE*3-Leiden.CETP mice.

Physiological reports

Zhang X, Paalvast Y, Wang Y, Rensen PCN, Groen AK.
PMID: 33932122
Physiol Rep. 2021 Apr;9(8):e14832. doi: 10.14814/phy2.14832.

BACKGROUND: Feed efficiency (FE) is an important trait for livestock and humans. While the livestock industry focuses on increasing FE, in the current obesogenic society it is more of interest to decrease FE. Hence, understanding mechanisms involved in the...

Showing 25 to 36 of 71 entries