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Showing 25 to 36 of 79 entries
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The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group.

NPJ breast cancer

El Bairi K, Haynes HR, Blackley E, Fineberg S, Shear J, Turner S, de Freitas JR, Sur D, Amendola LC, Gharib M, Kallala A, Arun I, Azmoudeh-Ardalan F, Fujimoto L, Sua LF, Liu SW, Lien HC, Kirtani P, Balancin M, El Attar H, Guleria P, Yang W, Shash E, Chen IC, Bautista V, Do Prado Moura JF, Rapoport BL, Castaneda C, Spengler E, Acosta-Haab G, Frahm I, Sanchez J, Castillo M, Bouchmaa N, Md Zin RR, Shui R, Onyuma T, Yang W, Husain Z, Willard-Gallo K, Coosemans A, Perez EA, Provenzano E, Ericsson PG, Richardet E, Mehrotra R, Sarancone S, Ehinger A, Rimm DL, Bartlett JMS, Viale G, Denkert C, Hida AI, Sotiriou C, Loibl S, Hewitt SM, Badve S, Symmans WF, Kim RS, Pruneri G, Goel S, Francis PA, Inurrigarro G, Yamaguchi R, Garcia-Rivello H, Horlings H, Afqir S, Salgado R, Adams S, Kok M, Dieci MV, Michiels S, Demaria S, Loi S.
PMID: 34853355
NPJ Breast Cancer. 2021 Dec 01;7(1):150. doi: 10.1038/s41523-021-00346-1.

The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly improved survival in several cancer settings. A subgroup of women with breast cancer (BC) has immunogenic infiltration of lymphocytes with expression of programmed death-ligand 1 (PD-L1). These patients...

Protein-Ribofuranosyl Interactions Activate Orotidine 5'-Monophosphate Decarboxylase for Catalysis.

Biochemistry

Cristobal JR, Brandão TAS, Reyes AC, Richard JP.
PMID: 34726391
Biochemistry. 2021 Nov 16;60(45):3362-3373. doi: 10.1021/acs.biochem.1c00589. Epub 2021 Nov 02.

The role of a global, substrate-driven, enzyme conformational change in enabling the extraordinarily large rate acceleration for orotidine 5'-monophosphate decarboxylase (OMPDC)-catalyzed decarboxylation of orotidine 5'-monophosphate (

Ventilatory and Autonomic Regulation in Sleep Apnea Syndrome: A Potential Protective Role for Erythropoietin?.

Frontiers in physiology

Andrade DC, Haine L, Toledo C, Diaz HS, Quintanilla RA, Marcus NJ, Iturriaga R, Richalet JP, Voituron N, Del Rio R.
PMID: 30374309
Front Physiol. 2018 Oct 16;9:1440. doi: 10.3389/fphys.2018.01440. eCollection 2018.

Obstructive sleep apnea (OSA) is the most common form of sleep disordered breathing and is associated with wide array of cardiovascular morbidities. It has been proposed that during OSA, the respiratory control center (RCC) is affected by exaggerated afferent...

Corrigendum to 'First-line nivolumab plus ipilimumab with 2 cycles of chemotherapy versus chemotherapy alone (4 cycles) in advanced non-small cell lung cancer: CheckMate 9LA 2-year update': [ESMO Open Volume 6, Issue 5, October 2021, 100273].

ESMO open

Reck M, Ciuleanu TE, Cobo M, Schenker M, Zurawski B, Menezes J, Richardet E, Bennouna J, Felip E, Juan-Vidal O, Alexandru A, Sakai H, Lingua A, Reyes F, Souquet PJ, De Marchi P, Martin C, Pérol M, Scherpereel A, Lu S, Paz-Ares L, Carbone DP, Memaj A, Marimuthu S, Zhang X, Tran P, John T.
PMID: 34864501
ESMO Open. 2021 Dec 02;6(6):100345. doi: 10.1016/j.esmoop.2021.100345. Epub 2021 Dec 02.

No abstract available.

The role of remote flavin adenine dinucleotide pieces in the oxidative decarboxylation catalyzed by salicylate hydroxylase.

Bioorganic chemistry

Pereira MS, de Araújo SS, Nagem RAP, Richard JP, Brandão TAS.
PMID: 34965488
Bioorg Chem. 2021 Dec 16;119:105561. doi: 10.1016/j.bioorg.2021.105561. Epub 2021 Dec 16.

Salicylate hydroxylase (NahG) has a single redox site in which FAD is reduced by NADH, the O

Exercising in Hypoxia and Other Stimuli: Heart Rate Variability and Ventilatory Oscillations.

Life (Basel, Switzerland)

Hermand E, Lhuissier FJ, Pichon A, Voituron N, Richalet JP.
PMID: 34203350
Life (Basel). 2021 Jun 28;11(7). doi: 10.3390/life11070625.

Periodic breathing is a respiratory phenomenon frequently observed in patients with heart failure and in normal subjects sleeping at high altitude. However, until recently, periodic breathing has not been studied in wakefulness and during exercise. This review relates the...

Correction to "Origin of Free Energy Barriers of Decarboxylation and the Reverse Process of CO.

Journal of the American Chemical Society

Zhou S, Nguyen BT, Richard JP, Kluger R, Gao J.
PMID: 33822616
J Am Chem Soc. 2021 Apr 21;143(15):6018. doi: 10.1021/jacs.1c03001. Epub 2021 Apr 06.

No abstract available.

Corrigendum to 'First-line nivolumab plus ipilimumab with 2 cycles of chemotherapy versus chemotherapy alone (4 cycles) in advanced non-small cell lung cancer: CheckMate 9LA 2-year update': [ESMO Open Volume 6, Issue 5, October 2021, 100273].

ESMO open

Reck M, Ciuleanu TE, Cobo M, Schenker M, Zurawski B, Menezes J, Richardet E, Bennouna J, Felip E, Juan-Vidal O, Alexandru A, Sakai H, Lingua A, Reyes F, Souquet PJ, De Marchi P, Martin C, Pérol M, Scherpereel A, Lu S, Paz-Ares L, Carbone DP, Memaj A, Marimuthu S, Zhang X, Tran P, John T.
PMID: 34864501
ESMO Open. 2021 Dec 02;6(6):100345. doi: 10.1016/j.esmoop.2021.100345. Epub 2021 Dec 02.

No abstract available.

Embryo quality, ploidy, and transfer outcomes in male versus female blastocysts.

Journal of assisted reproduction and genetics

Moutos CP, Kearns WG, Farmer SE, Richards JP, Saad AF, Crochet JR.
PMID: 34086149
J Assist Reprod Genet. 2021 Sep;38(9):2363-2370. doi: 10.1007/s10815-021-02250-w. Epub 2021 Jun 04.

PURPOSE: The goal is to determine if variations exist between male and female blastocysts in preimplantation measurements of quality and ploidy and in vitro fertilization elective single-embryo transfer (eSET) outcomes.METHODS: A retrospective chart review was conducted from a private...

Modelling the relationships between arterial oxygen saturation, exercise intensity and the level of aerobic performance in acute hypoxia.

European journal of applied physiology

Woorons X, Richalet JP.
PMID: 33782716
Eur J Appl Physiol. 2021 Jul;121(7):1993-2003. doi: 10.1007/s00421-021-04667-8. Epub 2021 Mar 30.

PURPOSE: The aim of this study was to establish a model to estimate the level of arterial oxygen saturation (SpOMETHODS: SpORESULTS: There were strong non-linear relationships between altitude and SpOCONCLUSION: The model demonstrates that the drop of SpO

Evaluation of the Lake Louise Score for Acute Mountain Sickness and Its 2018 Version in a Cohort of 484 Trekkers at High Altitude.

High altitude medicine & biology

Richalet JP, Julia C, Lhuissier FJ.
PMID: 34515528
High Alt Med Biol. 2021 Dec;22(4):353-361. doi: 10.1089/ham.2020.0226. Epub 2021 Sep 09.

Richalet, Jean-Paul, Chantal Julia, and François J. Lhuissier. Evaluation of the Lake Louise Score for acute mountain sickness and its 2018 version in a cohort of 484 trekkers at high altitude.

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group.

NPJ breast cancer

El Bairi K, Haynes HR, Blackley E, Fineberg S, Shear J, Turner S, de Freitas JR, Sur D, Amendola LC, Gharib M, Kallala A, Arun I, Azmoudeh-Ardalan F, Fujimoto L, Sua LF, Liu SW, Lien HC, Kirtani P, Balancin M, El Attar H, Guleria P, Yang W, Shash E, Chen IC, Bautista V, Do Prado Moura JF, Rapoport BL, Castaneda C, Spengler E, Acosta-Haab G, Frahm I, Sanchez J, Castillo M, Bouchmaa N, Md Zin RR, Shui R, Onyuma T, Yang W, Husain Z, Willard-Gallo K, Coosemans A, Perez EA, Provenzano E, Ericsson PG, Richardet E, Mehrotra R, Sarancone S, Ehinger A, Rimm DL, Bartlett JMS, Viale G, Denkert C, Hida AI, Sotiriou C, Loibl S, Hewitt SM, Badve S, Symmans WF, Kim RS, Pruneri G, Goel S, Francis PA, Inurrigarro G, Yamaguchi R, Garcia-Rivello H, Horlings H, Afqir S, Salgado R, Adams S, Kok M, Dieci MV, Michiels S, Demaria S, Loi S.
PMID: 34853355
NPJ Breast Cancer. 2021 Dec 01;7(1):150. doi: 10.1038/s41523-021-00346-1.

The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly improved survival in several cancer settings. A subgroup of women with breast cancer (BC) has immunogenic infiltration of lymphocytes with expression of programmed death-ligand 1 (PD-L1). These patients...

Showing 25 to 36 of 79 entries