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The Use of Intravitreal Anti-VEGF and Triamcinolone in the Treatment of Radiation Papillopathy.

Ocular oncology and pathology

Roelofs K, Larocque MP, Murtha A, Weis E.
PMID: 30574493
Ocul Oncol Pathol. 2018 Nov;4(6):395-400. doi: 10.1159/000487543. Epub 2018 Jun 08.

BACKGROUND/AIMS: To evaluate a treatment regimen for radiation papillopathy.METHODS: This is a prospective noncomparative interventional case series of patients who developed radiation papillopathy after plaque brachytherapy for uveal melanoma. Treatment consisted of intravitreal bevacizumab (IVB) (1.25 mg in 0.05...

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Roelofs K, Larocque MP, Murtha A, et al. The Use of Intravitreal Anti-VEGF and Triamcinolone in the Treatment of Radiation Papillopathy. Ocul Oncol Pathol. 2018;4(6):395-400doi: 10.1159/000487543.
Roelofs, K., Larocque, M. P., Murtha, A., & Weis, E. (2018). The Use of Intravitreal Anti-VEGF and Triamcinolone in the Treatment of Radiation Papillopathy. Ocular oncology and pathology, 4(6), 395-400. https://doi.org/10.1159/000487543
Roelofs, Kelsey, et al. "The Use of Intravitreal Anti-VEGF and Triamcinolone in the Treatment of Radiation Papillopathy." Ocular oncology and pathology vol. 4,6 (2018): 395-400. doi: https://doi.org/10.1159/000487543
Roelofs K, Larocque MP, Murtha A, Weis E. The Use of Intravitreal Anti-VEGF and Triamcinolone in the Treatment of Radiation Papillopathy. Ocul Oncol Pathol. 2018 Nov;4(6):395-400. doi: 10.1159/000487543. Epub 2018 Jun 08. PMID: 30574493; PMCID: PMC6288662.
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Proteaphagy is specifically regulated and requires factors dispensable for general autophagy.

The Journal of biological chemistry

Waite KA, Burris A, Vontz G, Lang A, Roelofs J.
PMID: 34919962
J Biol Chem. 2021 Dec 14;298(1):101494. doi: 10.1016/j.jbc.2021.101494. Epub 2021 Dec 14.

Changing physiological conditions can increase the need for protein degradative capacity in eukaryotic cells. Both the ubiquitin-proteasome system and autophagy contribute to protein degradation. However, these processes can be differently regulated depending on the physiological conditions. Strikingly, proteasomes themselves...

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Waite KA, Burris A, Vontz G, et al. Proteaphagy is specifically regulated and requires factors dispensable for general autophagy. J Biol Chem. 2021;298(1):101494doi: 10.1016/j.jbc.2021.101494.
Waite, K. A., Burris, A., Vontz, G., Lang, A., & Roelofs, J. (2021). Proteaphagy is specifically regulated and requires factors dispensable for general autophagy. The Journal of biological chemistry, 298(1), 101494. https://doi.org/10.1016/j.jbc.2021.101494
Waite, Kenrick A, et al. "Proteaphagy is specifically regulated and requires factors dispensable for general autophagy." The Journal of biological chemistry vol. 298,1 (2021): 101494. doi: https://doi.org/10.1016/j.jbc.2021.101494
Waite KA, Burris A, Vontz G, Lang A, Roelofs J. Proteaphagy is specifically regulated and requires factors dispensable for general autophagy. J Biol Chem. 2021 Dec 14;298(1):101494. doi: 10.1016/j.jbc.2021.101494. Epub 2021 Dec 14. PMID: 34919962.
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Proteaphagy is specifically regulated and requires factors dispensable for general autophagy.

The Journal of biological chemistry

Waite KA, Burris A, Vontz G, Lang A, Roelofs J.
PMID: 34919962
J Biol Chem. 2021 Dec 14;298(1):101494. doi: 10.1016/j.jbc.2021.101494. Epub 2021 Dec 14.

Changing physiological conditions can increase the need for protein degradative capacity in eukaryotic cells. Both the ubiquitin-proteasome system and autophagy contribute to protein degradation. However, these processes can be differently regulated depending on the physiological conditions. Strikingly, proteasomes themselves...

Cite
Waite KA, Burris A, Vontz G, et al. Proteaphagy is specifically regulated and requires factors dispensable for general autophagy. J Biol Chem. 2021;298(1):101494doi: 10.1016/j.jbc.2021.101494.
Waite, K. A., Burris, A., Vontz, G., Lang, A., & Roelofs, J. (2021). Proteaphagy is specifically regulated and requires factors dispensable for general autophagy. The Journal of biological chemistry, 298(1), 101494. https://doi.org/10.1016/j.jbc.2021.101494
Waite, Kenrick A, et al. "Proteaphagy is specifically regulated and requires factors dispensable for general autophagy." The Journal of biological chemistry vol. 298,1 (2021): 101494. doi: https://doi.org/10.1016/j.jbc.2021.101494
Waite KA, Burris A, Vontz G, Lang A, Roelofs J. Proteaphagy is specifically regulated and requires factors dispensable for general autophagy. J Biol Chem. 2021 Dec 14;298(1):101494. doi: 10.1016/j.jbc.2021.101494. Epub 2021 Dec 14. PMID: 34919962; PMCID: PMC8732087.
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The ROCOCO performance scoring system translates dosimetric differences into clinically relevant endpoints: Comparing IMPT to VMAT in an example pilocytic astrocytoma dataset.

Clinical and translational radiation oncology

In 't Ven L, Roelofs E, Cubillos Mesías M, Compter I, Klaver YLB, Smeenk RJ, Janssens GO, Kaanders JHAM, Fajardo RD, Oldenburger F, de Ruysscher D, Troost EGC, Eekers DBP.
PMID: 33748441
Clin Transl Radiat Oncol. 2021 Feb 22;28:32-38. doi: 10.1016/j.ctro.2021.02.006. eCollection 2021 May.

BACKGROUND AND PURPOSE: Proton therapy is expected to outperform photon-based treatment regarding organs at risk (OAR) sparing but to date there is no method to practically measure clinical benefit. Here, we introduce the novel ROCOCO Performance Scoring System (RPSS)...

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In 't Ven L, Roelofs E, Cubillos Mesías M, et al. The ROCOCO performance scoring system translates dosimetric differences into clinically relevant endpoints: Comparing IMPT to VMAT in an example pilocytic astrocytoma dataset. Clin Transl Radiat Oncol. 2021;28:32-38doi: 10.1016/j.ctro.2021.02.006.
In 't Ven, L., Roelofs, E., Cubillos Mesías, M., Compter, I., Klaver, Y. L. B., Smeenk, R. J., Janssens, G. O., Kaanders, J. H. A. M., Fajardo, R. D., Oldenburger, F., de Ruysscher, D., Troost, E. G. C., & Eekers, D. B. P. (2021). The ROCOCO performance scoring system translates dosimetric differences into clinically relevant endpoints: Comparing IMPT to VMAT in an example pilocytic astrocytoma dataset. Clinical and translational radiation oncology, 2832-38. https://doi.org/10.1016/j.ctro.2021.02.006
In 't Ven, Lieke, et al. "The ROCOCO performance scoring system translates dosimetric differences into clinically relevant endpoints: Comparing IMPT to VMAT in an example pilocytic astrocytoma dataset." Clinical and translational radiation oncology vol. 28 (2021): 32-38. doi: https://doi.org/10.1016/j.ctro.2021.02.006
In 't Ven L, Roelofs E, Cubillos Mesías M, Compter I, Klaver YLB, Smeenk RJ, Janssens GO, Kaanders JHAM, Fajardo RD, Oldenburger F, de Ruysscher D, Troost EGC, Eekers DBP. The ROCOCO performance scoring system translates dosimetric differences into clinically relevant endpoints: Comparing IMPT to VMAT in an example pilocytic astrocytoma dataset. Clin Transl Radiat Oncol. 2021 Feb 22;28:32-38. doi: 10.1016/j.ctro.2021.02.006. eCollection 2021 May. PMID: 33748441; PMCID: PMC7966832.
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The role of psychopathic traits, social anxiety and cortisol in social approach avoidance tendencies.

Psychoneuroendocrinology

Dapprich AL, Lange WG, von Borries AKL, Volman I, Figner B, Roelofs K.
PMID: 33799172
Psychoneuroendocrinology. 2021 Jun;128:105207. doi: 10.1016/j.psyneuen.2021.105207. Epub 2021 Mar 24.

Social anxiety and psychopathy have conceptually been linked to nearly opposite emotional, behavioral and endocrinological endophenotypes, representing social fearfulness and fearlessness, respectively. Although such a dimensional view has theoretical and practical implications, no study has directly compared social anxiety...

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Dapprich AL, Lange WG, von Borries AKL, et al. The role of psychopathic traits, social anxiety and cortisol in social approach avoidance tendencies. Psychoneuroendocrinology. 2021;128:105207doi: 10.1016/j.psyneuen.2021.105207.
Dapprich, A. L., Lange, W. G., von Borries, A. K. L., Volman, I., Figner, B., & Roelofs, K. (2021). The role of psychopathic traits, social anxiety and cortisol in social approach avoidance tendencies. Psychoneuroendocrinology, 128105207. https://doi.org/10.1016/j.psyneuen.2021.105207
Dapprich, Anna L, et al. "The role of psychopathic traits, social anxiety and cortisol in social approach avoidance tendencies." Psychoneuroendocrinology vol. 128 (2021): 105207. doi: https://doi.org/10.1016/j.psyneuen.2021.105207
Dapprich AL, Lange WG, von Borries AKL, Volman I, Figner B, Roelofs K. The role of psychopathic traits, social anxiety and cortisol in social approach avoidance tendencies. Psychoneuroendocrinology. 2021 Jun;128:105207. doi: 10.1016/j.psyneuen.2021.105207. Epub 2021 Mar 24. PMID: 33799172.
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Charge-based scanning probe readback of nanometer-scale ferroelectric domain patterns at megahertz rates.

Nanotechnology

Forrester MG, Ahner JW, Bedillion MD, Bedoya C, Bolten DG, Chang KC, de Gersem G, Hu S, Johns EC, Nassirou M, Palmer J, Roelofs A, Siegert M, Tamaru S, Vaithyanathan V, Zavaliche F, Zhao T, Zhao Y.
PMID: 19436094
Nanotechnology. 2009 Jun 03;20(22):225501. doi: 10.1088/0957-4484/20/22/225501. Epub 2009 May 13.

We present a method for data storage in continuous ferroelectric (FE) media, applicable to storage systems based on one or more scanning probes. Written FE domains are read back in a destructive fashion by applying a constant voltage of...

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Forrester MG, Ahner JW, Bedillion MD, et al. Charge-based scanning probe readback of nanometer-scale ferroelectric domain patterns at megahertz rates. Nanotechnology. 2009;20(22):225501doi: 10.1088/0957-4484/20/22/225501.
Forrester, M. G., Ahner, J. W., Bedillion, M. D., Bedoya, C., Bolten, D. G., Chang, K. C., de Gersem, G., Hu, S., Johns, E. C., Nassirou, M., Palmer, J., Roelofs, A., Siegert, M., Tamaru, S., Vaithyanathan, V., Zavaliche, F., Zhao, T., & Zhao, Y. (2009). Charge-based scanning probe readback of nanometer-scale ferroelectric domain patterns at megahertz rates. Nanotechnology, 20(22), 225501. https://doi.org/10.1088/0957-4484/20/22/225501
Forrester, Martin G, et al. "Charge-based scanning probe readback of nanometer-scale ferroelectric domain patterns at megahertz rates." Nanotechnology vol. 20,22 (2009): 225501. doi: https://doi.org/10.1088/0957-4484/20/22/225501
Forrester MG, Ahner JW, Bedillion MD, Bedoya C, Bolten DG, Chang KC, de Gersem G, Hu S, Johns EC, Nassirou M, Palmer J, Roelofs A, Siegert M, Tamaru S, Vaithyanathan V, Zavaliche F, Zhao T, Zhao Y. Charge-based scanning probe readback of nanometer-scale ferroelectric domain patterns at megahertz rates. Nanotechnology. 2009 Jun 03;20(22):225501. doi: 10.1088/0957-4484/20/22/225501. Epub 2009 May 13. PMID: 19436094.
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Targeting the IL-6-Yap-Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis.

Annals of the rheumatic diseases

Symons RA, Colella F, Collins FL, Rafipay AJ, Kania K, McClure JJ, White N, Cunningham I, Ashraf S, Hay E, Mackenzie KS, Howard KA, Riemen AHK, Manzo A, Clark SM, Roelofs AJ, De Bari C.
PMID: 34844926
Ann Rheum Dis. 2021 Nov 29; doi: 10.1136/annrheumdis-2021-220875. Epub 2021 Nov 29.

OBJECTIVE: We aimed to understand the role of the transcriptional co-factor Yes-associated protein (Yap) in the molecular pathway underpinning the pathogenic transformation of synovial fibroblasts (SF) in rheumatoid arthritis (RA) to become invasive and cause joint destruction.METHODS: Synovium from...

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Symons RA, Colella F, Collins FL, et al. Targeting the IL-6-Yap-Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis. Ann Rheum Dis. 2021;doi: 10.1136/annrheumdis-2021-220875.
Symons, R. A., Colella, F., Collins, F. L., Rafipay, A. J., Kania, K., McClure, J. J., White, N., Cunningham, I., Ashraf, S., Hay, E., Mackenzie, K. S., Howard, K. A., Riemen, A. H. K., Manzo, A., Clark, S. M., Roelofs, A. J., & De Bari, C. (2021). Targeting the IL-6-Yap-Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis. Annals of the rheumatic diseases, . https://doi.org/10.1136/annrheumdis-2021-220875
Symons, Rebecca A, et al. "Targeting the IL-6-Yap-Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis." Annals of the rheumatic diseases vol. (2021). doi: https://doi.org/10.1136/annrheumdis-2021-220875
Symons RA, Colella F, Collins FL, Rafipay AJ, Kania K, McClure JJ, White N, Cunningham I, Ashraf S, Hay E, Mackenzie KS, Howard KA, Riemen AHK, Manzo A, Clark SM, Roelofs AJ, De Bari C. Targeting the IL-6-Yap-Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis. Ann Rheum Dis. 2021 Nov 29; doi: 10.1136/annrheumdis-2021-220875. Epub 2021 Nov 29. PMID: 34844926.
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The Effects of Ethno-cultural Origin-Destination Interactions on Immigrants' Longevity.

Journal of immigrant and minority health

Roelfs DJ, Shor E.
PMID: 34529210
J Immigr Minor Health. 2021 Sep 16; doi: 10.1007/s10903-021-01245-0. Epub 2021 Sep 16.

A large body of research has documented an immigrant mortality advantage. However, we still do not know enough about how interactions between the characteristics of origin and destinations countries shape variabilities in immigrants' experiences and health. In this paper,...

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Roelfs DJ, Shor E. The Effects of Ethno-cultural Origin-Destination Interactions on Immigrants' Longevity. J Immigr Minor Health. 2021;doi: 10.1007/s10903-021-01245-0.
Roelfs, D. J., & Shor, E. (2021). The Effects of Ethno-cultural Origin-Destination Interactions on Immigrants' Longevity. Journal of immigrant and minority health, . https://doi.org/10.1007/s10903-021-01245-0
Roelfs, David J, and Shor, Eran. "The Effects of Ethno-cultural Origin-Destination Interactions on Immigrants' Longevity." Journal of immigrant and minority health vol. (2021). doi: https://doi.org/10.1007/s10903-021-01245-0
Roelfs DJ, Shor E. The Effects of Ethno-cultural Origin-Destination Interactions on Immigrants' Longevity. J Immigr Minor Health. 2021 Sep 16; doi: 10.1007/s10903-021-01245-0. Epub 2021 Sep 16. PMID: 34529210.
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Exploring the course of adolescent anxiety and depression: associations with white matter tract microstructure.

European archives of psychiatry and clinical neuroscience

Roelofs EF, Bas-Hoogendam JM, van der Werff SJA, Valstar SD, van der Wee NJA, Vermeiren RRJM.
PMID: 34748029
Eur Arch Psychiatry Clin Neurosci. 2021 Nov 08; doi: 10.1007/s00406-021-01347-8. Epub 2021 Nov 08.

Cross-sectional Diffusion Tensor Imaging (DTI) studies have reported alterations in white matter (WM) microstructure in adolescents with internalizing psychopathology. Yet, longitudinal studies investigating the course of WM microstructure are lacking. This study explored WM alterations and its relation to...

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Roelofs EF, Bas-Hoogendam JM, van der Werff SJA, et al. Exploring the course of adolescent anxiety and depression: associations with white matter tract microstructure. Eur Arch Psychiatry Clin Neurosci. 2021;doi: 10.1007/s00406-021-01347-8.
Roelofs, E. F., Bas-Hoogendam, J. M., van der Werff, S. J. A., Valstar, S. D., van der Wee, N. J. A., & Vermeiren, R. R. J. M. (2021). Exploring the course of adolescent anxiety and depression: associations with white matter tract microstructure. European archives of psychiatry and clinical neuroscience, . https://doi.org/10.1007/s00406-021-01347-8
Roelofs, Eline F, et al. "Exploring the course of adolescent anxiety and depression: associations with white matter tract microstructure." European archives of psychiatry and clinical neuroscience vol. (2021). doi: https://doi.org/10.1007/s00406-021-01347-8
Roelofs EF, Bas-Hoogendam JM, van der Werff SJA, Valstar SD, van der Wee NJA, Vermeiren RRJM. Exploring the course of adolescent anxiety and depression: associations with white matter tract microstructure. Eur Arch Psychiatry Clin Neurosci. 2021 Nov 08; doi: 10.1007/s00406-021-01347-8. Epub 2021 Nov 08. PMID: 34748029.
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Proteaphagy is specifically regulated and requires factors dispensable for general autophagy.

The Journal of biological chemistry

Waite KA, Burris A, Vontz G, Lang A, Roelofs J.
PMID: 34919962
J Biol Chem. 2021 Dec 14;101494. doi: 10.1016/j.jbc.2021.101494. Epub 2021 Dec 14.

Changing physiological conditions can increase the need for protein degradative capacity in eukaryotic cells. Both the ubiquitin-proteasome system and autophagy contribute to protein degradation. However, these processes can be differently regulated depending on the physiological conditions. Strikingly, proteasomes themselves...

Cite
Waite KA, Burris A, Vontz G, et al. Proteaphagy is specifically regulated and requires factors dispensable for general autophagy. J Biol Chem. 2021;101494doi: 10.1016/j.jbc.2021.101494.
Waite, K. A., Burris, A., Vontz, G., Lang, A., & Roelofs, J. (2021). Proteaphagy is specifically regulated and requires factors dispensable for general autophagy. The Journal of biological chemistry, 101494. https://doi.org/10.1016/j.jbc.2021.101494
Waite, Kenrick A, et al. "Proteaphagy is specifically regulated and requires factors dispensable for general autophagy." The Journal of biological chemistry vol. (2021): 101494. doi: https://doi.org/10.1016/j.jbc.2021.101494
Waite KA, Burris A, Vontz G, Lang A, Roelofs J. Proteaphagy is specifically regulated and requires factors dispensable for general autophagy. J Biol Chem. 2021 Dec 14;101494. doi: 10.1016/j.jbc.2021.101494. Epub 2021 Dec 14. PMID: 34919962.
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Sunlamp use is a risk factor for uveal melanoma: a meta-analysis.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie

Weis E, Aghazadeh H, Roelofs K, Agi J.
PMID: 33839068
Can J Ophthalmol. 2021 Apr 08; doi: 10.1016/j.jcjo.2021.02.041. Epub 2021 Apr 08.

OBJECTIVE: Advancements in the treatment of uveal melanoma have not improved survival; therefore, identifying modifiable risk factors is critical to improving outcomes. This study aims to investigate the association between sunlamp use and the development of uveal melanoma.DESIGN: This...

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Weis E, Aghazadeh H, Roelofs K, et al. Sunlamp use is a risk factor for uveal melanoma: a meta-analysis. Can J Ophthalmol. 2021;doi: 10.1016/j.jcjo.2021.02.041.
Weis, E., Aghazadeh, H., Roelofs, K., & Agi, J. (2021). Sunlamp use is a risk factor for uveal melanoma: a meta-analysis. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, . https://doi.org/10.1016/j.jcjo.2021.02.041
Weis, Ezekiel, et al. "Sunlamp use is a risk factor for uveal melanoma: a meta-analysis." Canadian journal of ophthalmology. Journal canadien d'ophtalmologie vol. (2021). doi: https://doi.org/10.1016/j.jcjo.2021.02.041
Weis E, Aghazadeh H, Roelofs K, Agi J. Sunlamp use is a risk factor for uveal melanoma: a meta-analysis. Can J Ophthalmol. 2021 Apr 08; doi: 10.1016/j.jcjo.2021.02.041. Epub 2021 Apr 08. PMID: 33839068.
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[No title available]

Microorganisms

Jiménez E, Manzano S, Schlembach D, Arciszewski K, Martin R, Ben Amor K, Roelofs M, Knol J, Rodríguez JM, Abou-Dakn M, Premium Study Group.
PMID: 34576828
Microorganisms. 2021 Sep 11;9(9). doi: 10.3390/microorganisms9091933.

Mastitis is considered one of the main reasons for unwanted breastfeeding cessation. This study aimed to investigate the preventive effect of the probiotic strain

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Jiménez E, Manzano S, Schlembach D, et al. . Microorganisms. 2021;9(9)doi: 10.3390/microorganisms9091933.
Jiménez, E., Manzano, S., Schlembach, D., Arciszewski, K., Martin, R., Ben Amor, K., Roelofs, M., Knol, J., Rodríguez, J. M., Abou-Dakn, M., & Premium Study Group. (2021). . Microorganisms, 9(9), . https://doi.org/10.3390/microorganisms9091933
Jiménez, Esther, et al. "." Microorganisms vol. 9,9 (2021). doi: https://doi.org/10.3390/microorganisms9091933
Jiménez E, Manzano S, Schlembach D, Arciszewski K, Martin R, Ben Amor K, Roelofs M, Knol J, Rodríguez JM, Abou-Dakn M, Premium Study Group. . Microorganisms. 2021 Sep 11;9(9). doi: 10.3390/microorganisms9091933. PMID: 34576828; PMCID: PMC8469334.
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Showing 25 to 36 of 186 entries