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Showing 25 to 36 of 165 entries
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Matriptase-2: monitoring and inhibiting its proteolytic activity.

Future medicinal chemistry

Gitlin-Domagalska A, Mangold M, Dębowski D, Ptaszyńska N, Łęgowska A, Gütschow M, Rolka K.
PMID: 30518272
Future Med Chem. 2018 Dec 06; doi: 10.4155/fmc-2018-0346. Epub 2018 Dec 06.

Matriptase-2 (MT2) is a membrane-anchored proteolytic enzyme. It acts as the proteolytic key regulator in human iron homeostasis. A high expression level can lead to iron overload diseases, whereas mutations in the gene encoding MT2, TMPRSS6, may result in...

Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts.

The Journal of experimental medicine

Kerdidani D, Aerakis E, Verrou KM, Angelidis I, Douka K, Maniou MA, Stamoulis P, Goudevenou K, Prados A, Tzaferis C, Ntafis V, Vamvakaris I, Kaniaris E, Vachlas K, Sepsas E, Koutsopoulos A, Potaris K, Tsoumakidou M.
PMID: 35029648
J Exp Med. 2022 Feb 07;219(2). doi: 10.1084/jem.20210815. Epub 2022 Jan 14.

A key unknown of the functional space in tumor immunity is whether CD4 T cells depend on intratumoral MHCII cancer antigen recognition. MHCII-expressing, antigen-presenting cancer-associated fibroblasts (apCAFs) have been found in breast and pancreatic tumors and are considered to...

The earliest Denisovans and their cultural adaptation.

Nature ecology & evolution

Brown S, Massilani D, Kozlikin MB, Shunkov MV, Derevianko AP, Stoessel A, Jope-Street B, Meyer M, Kelso J, Pääbo S, Higham T, Douka K.
PMID: 34824388
Nat Ecol Evol. 2022 Jan;6(1):28-35. doi: 10.1038/s41559-021-01581-2. Epub 2021 Nov 25.

Since the initial identification of the Denisovans a decade ago, only a handful of their physical remains have been discovered. Here we analysed ~3,800 non-diagnostic bone fragments using collagen peptide mass fingerprinting to locate new hominin remains from Denisova...

Organic carbon accumulation in the glacier forelands with regard to variability of environmental conditions in different ecogenesis stages of High Arctic ecosystems.

The Science of the total environment

Wietrzyk-Pełka P, Rola K, Szymański W, Węgrzyn MH.
PMID: 31839323
Sci Total Environ. 2020 May 15;717:135151. doi: 10.1016/j.scitotenv.2019.135151. Epub 2019 Nov 21.

Recently deglaciated surfaces of glacier forelands are subjected to a variety of biotic and abiotic factors that lead to continuous soil formation. Until now, no attempt has been taken to analyse multiple factors that might affect soil development in...

Lymphoepithelial Cyst of the Salivary Gland in a Small Ruminant Lentivirus-Positive Goat.

Animals : an open access journal from MDPI

Dolka I, Tomaszewski M, Wola D, Czopowicz M, Kaba J.
PMID: 32882962
Animals (Basel). 2020 Sep 01;10(9). doi: 10.3390/ani10091545.

The lymphoepithelial cyst (LEC) of the major salivary gland is a rare lesion described in medical literature. It is found in human immunodeficiency virus (HIV)-infected patients and considered an early manifestation of this infection. Despite the variety of theories,...

Correction: Stability of Cu(II) complexes with FomA protein fragments containing two His residues in the peptide chain.

Metallomics : integrated biometal science

Lesiów MK, Pietrzyk P, Bieńko A, Kowalik-Jankowska T, Łęgowska A, Ptaszyńska N, Rolka K.
PMID: 33320153
Metallomics. 2020 Dec 23;12(12):2199. doi: 10.1039/d0mt90038a.

Correction for 'Stability of Cu(ii) complexes with FomA protein fragments containing two His residues in the peptide chain' by Monika Katarzyna Lesiów et al., Metallomics, 2019, 11, 1518-1531, DOI: 10.1039/C9MT00131J.

Before and after farming: The genetic structure of South China and Southeast Asia.

Cell

Pinhasi R, Douka K.
PMID: 34242562
Cell. 2021 Jul 08;184(14):3597-3598. doi: 10.1016/j.cell.2021.06.016.

In this issue of Cell, Wang et al. harness ancient DNA methods to produce and analyze new genomic data from 31 individuals from South China, dated between 500 and 10,000-12,000 years ago. The study reveals a complex interplay between...

Data on cryptogamic biota in relation to heavy metal concentrations in soil.

Data in brief

Rola K, Osyczka P.
PMID: 30228998
Data Brief. 2018 May 31;19:1110-1119. doi: 10.1016/j.dib.2018.05.137. eCollection 2018 Aug.

The data presented here are related to the research article entitled "Cryptogamic communities as a useful bioindication tool for estimating the degree of soil pollution with heavy metals" (Rola and Osyczka, 2018) [1]. These data concern the relationships between...

Identifying optimal survey-based algorithms to distinguish diabetes type among adults with diabetes.

Journal of clinical & translational endocrinology

Nooney JG, Kirkman MS, Bullard KM, White Z, Meadows K, Campione JR, Mardon R, Rivero G, Benoit SR, Pfaff E, Rolka D, Saydah S.
PMID: 32695611
J Clin Transl Endocrinol. 2020 Jul 03;21:100231. doi: 10.1016/j.jcte.2020.100231. eCollection 2020 Sep.

OBJECTIVES: Surveys for U.S. diabetes surveillance do not reliably distinguish between type 1 and type 2 diabetes, potentially obscuring trends in type 1 among adults. To validate survey-based algorithms for distinguishing diabetes type, we linked survey data collected from...

A Review of Current Knowledge on .

Animals : an open access journal from MDPI

Szafraniec GM, Szeleszczuk P, Dolka B.
PMID: 32823920
Animals (Basel). 2020 Aug 14;10(8). doi: 10.3390/ani10081421.

This review aims to summarize recent discoveries and advancements regarding the characteristics of

Insight into the pattern of heavy-metal accumulation in lichen thalli.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

Rola K.
PMID: 32299012
J Trace Elem Med Biol. 2020 Apr 04;61:126512. doi: 10.1016/j.jtemb.2020.126512. Epub 2020 Apr 04.

BACKGROUND: Heavy metals that pass through the plasmalemma are expected to influence on lichen metabolic processes; however, lichens may tolerate high concentrations of metals by sequestrating them extracellularly. Heavy metal accumulation level fundamentally determine the success of lichens in...

Epilepsy, ataxia, sensorineural deafness, tubulopathy syndrome in a European child with .

SAGE open medical case reports

Papavasiliou A, Foska K, Ioannou J, Nagel M.
PMID: 28835827
SAGE Open Med Case Rep. 2017 Jul 27;5:2050313X17723549. doi: 10.1177/2050313X17723549. eCollection 2017.

BACKGROUND: Epilepsy, ataxia, sensorineural deafness, tubulopathy syndrome is a multi-organ disorder that links to autosomal recessive mutations in the CASE REPORT: A European male of non-consanguineous birth, with early-onset, static ataxic motor disorder, intellectual disability and epilepsy, imitating cerebral...

Showing 25 to 36 of 165 entries