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Showing 13 to 24 of 166 entries
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Human Th1 dichotomy: origin, phenotype and biologic activities.

Immunology

Annunziato F, Cosmi L, Liotta F, Maggi E, Romagnani S.
PMID: 25284714
Immunology. 2014 Oct 05; doi: 10.1111/imm.12399. Epub 2014 Oct 05.

The great variety of pathogens present in the environment has obliged the immune system to evolve different mechanisms for tailored and maximally protective responses. Initially, two major types of CD4+ T helper (Th) effector cells were identified, and named...

A Novel Saccadic Strategy Revealed by Suppression Head Impulse Testing of Patients with Bilateral Vestibular Loss.

Frontiers in neurology

de Waele C, Shen Q, Magnani C, Curthoys IS.
PMID: 28868046
Front Neurol. 2017 Aug 18;8:419. doi: 10.3389/fneur.2017.00419. eCollection 2017.

OBJECTIVE: We examined the eye movement response patterns of a group of patients with bilateral vestibular loss (BVL) during suppression head impulse testing. Some showed a new saccadic strategy that may have potential for explaining how patients use saccades...

The effect of strontium chloride on human periodontal ligament stem cells.

Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases

Romagnoli C, Zonefrati R, Galli G, Aldinucci A, Nuti N, Martelli FS, Tonelli P, Tanini A, Brandi ML.
PMID: 29354155
Clin Cases Miner Bone Metab. 2017 Sep-Dec;14(3):283-293. doi: 10.11138/ccmbm/2017.14.3.283. Epub 2017 Dec 27.

The complete repair of periodontal structures remains an exciting challenge that prompts researchers to develop new treatments to restore the periodontium. Recent research has suggested strontium ion to be an attractive candidate to improve osteogenic activity. In this study,...

SARS-CoV-2 Positive Hospitalized Cancer Patients during the Italian Outbreak: The Cohort Study in Reggio Emilia.

Biology

Pinto C, Berselli A, Mangone L, Damato A, Iachetta F, Foracchia M, Zanelli F, Gervasi E, Romagnani A, Prati G, Lui S, Venturelli F, Vicentini M, Besutti G, De Palma R, Giorgi Rossi P.
PMID: 32707770
Biology (Basel). 2020 Jul 22;9(8). doi: 10.3390/biology9080181.

In the coronavirus disease (COVID-19) pandemic, cancer patients could be a high-risk group due to their immunosuppressed status; therefore, data on cancer patients must be available in order to consider the most adequate strategy of care. We carried out...

FOLFOXIRI/Bevacizumab Plus Nivolumab as First-Line Treatment in Metastatic Colorectal Cancer RAS/BRAF Mutated: Safety Run-In of Phase II NIVACOR Trial.

Frontiers in oncology

Damato A, Bergamo F, Antonuzzo L, Nasti G, Iachetta F, Romagnani A, Gervasi E, Larocca M, Pinto C.
PMID: 34970487
Front Oncol. 2021 Dec 14;11:766500. doi: 10.3389/fonc.2021.766500. eCollection 2021.

The NIVACOR trial is a phase II study assessing the efficacy and safety of nivolumab in combination with FOLFOXIRI/bevacizumab in first-line setting in patients affected by metastatic colorectal cancer (mCRC) RAS/BRAF mutated. We report safety run-in results in the...

Effect of Asbestos Consumption on Malignant Pleural Mesothelioma in Italy: Forecasts of Mortality up to 2040.

Cancers

Oddone E, Bollon J, Nava CR, Consonni D, Marinaccio A, Magnani C, Gasparrini A, Barone-Adesi F.
PMID: 34283067
Cancers (Basel). 2021 Jul 03;13(13). doi: 10.3390/cancers13133338.

Statistical models used to forecast malignant pleural mesothelioma (MPM) trends often do not take into account historical asbestos consumption, possibly resulting in less accurate predictions of the future MPM death toll. We used the distributed lag non-linear model (DLNM)...

Slowly progressive anti-neutrophil cytoplasmic antibody-associated renal vasculitis: clinico-pathological characterization and outcome.

Clinical kidney journal

Trivioli G, Gopaluni S, Urban ML, Gianfreda D, Cassia MA, Vercelloni PG, Calatroni M, Bettiol A, Esposito P, Murtas C, Alberici F, Maritati F, Manenti L, Palmisano A, Emmi G, Romagnani P, Moroni G, Gregorini G, Sinico RA, Jayne DRW, Vaglio A.
PMID: 33564436
Clin Kidney J. 2020 Sep 06;14(1):332-340. doi: 10.1093/ckj/sfaa139. eCollection 2021 Jan.

BACKGROUND: Although rapidly progressive glomerulonephritis is the main renal phenotype of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), slow renal disease progression is sometimes observed. These forms have been rarely discussed; we analysed their prevalence, clinico-pathological characteristics and outcome.METHODS: We...

Muscle Physiopathology in Parathyroid Hormone Disorders.

Frontiers in medicine

Romagnoli C, Brandi ML.
PMID: 34746197
Front Med (Lausanne). 2021 Oct 22;8:764346. doi: 10.3389/fmed.2021.764346. eCollection 2021.

Parathyroid hormone disorders are a group of diseases in which secretion of parathormone (PTH) is impaired. The disorders that result are characterized by signs and symptoms associated with the persistent presence of high blood calcium levels (hypercalcemia) related to...

Deletion of lysophosphatidylcholine acyltransferase 3 in myeloid cells worsens hepatic steatosis after a high-fat diet.

Journal of lipid research

Bourgeois T, Jalil A, Thomas C, Magnani C, Le Guern N, Gautier T, Pais de Barros JP, Bergas V, Choubley H, Mazzeo L, Menegaut L, Josiane Lebrun L, Van Dongen K, Xolin M, Jourdan T, Buch C, Labbé J, Saas P, Lagrost L, Masson D, Grober J.
PMID: 33518513
J Lipid Res. 2020 Dec 17;62:100013. doi: 10.1194/jlr.RA120000737. Epub 2020 Dec 17.

Recent studies have highlighted an important role for lysophosphatidylcholine acyltransferase 3 (LPCAT3) in controlling the PUFA composition of cell membranes in the liver and intestine. In these organs, LPCAT3 critically supports cell-membrane-associated processes such as lipid absorption or lipoprotein...

Malignant pleural mesothelioma: Germline variants in DNA repair genes may steer tailored treatment.

European journal of cancer (Oxford, England : 1990)

Sculco M, La Vecchia M, Aspesi A, Pinton G, Clavenna MG, Casalone E, Allione A, Grosso F, Libener R, Muzio A, Rena O, Baietto G, Parini S, Boldorini R, Giachino D, Papotti M, Scagliotti GV, Migliore E, Mirabelli D, Moro L, Magnani C, Ferrante D, Matullo G, Dianzani I.
PMID: 35032816
Eur J Cancer. 2022 Jan 12;163:44-54. doi: 10.1016/j.ejca.2021.12.023. Epub 2022 Jan 12.

INTRODUCTION: Malignant pleural mesothelioma (MPM) is a tumour associated with asbestos exposure. Approximately, 10% of patients with MPM carry a germline pathogenic variant (PV), mostly in DNA repair genes, suggesting the occurrence of inherited predispositions.AIM: This article aimed to...

Weibel-induced filamentation during an ultrafast laser-driven plasma expansion.

Physical review letters

Quinn K, Romagnani L, Ramakrishna B, Sarri G, Dieckmann ME, Wilson PA, Fuchs J, Lancia L, Pipahl A, Toncian T, Willi O, Clarke RJ, Notley M, Macchi A, Borghesi M.
PMID: 22540706
Phys Rev Lett. 2012 Mar 30;108(13):135001. doi: 10.1103/PhysRevLett.108.135001. Epub 2012 Mar 26.

The development of current instabilities behind the front of a cylindrically expanding plasma has been investigated experimentally via proton probing techniques. A multitude of tubelike filamentary structures is observed to form behind the front of a plasma created by...

Comparison of prostate MRI-3D transrectal ultrasound fusion biopsy for first-time and repeat biopsy patients with previous atypical small acinar proliferation.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada

Cool DW, Romagnoli C, Izawa JI, Chin J, Gardi L, Tessier D, Mercado A, Mandel J, Ward AD, Fenster A.
PMID: 27800057
Can Urol Assoc J. 2016 Sep-Oct;10(9):342-348. doi: 10.5489/cuaj.3831.

INTRODUCTION: This study evaluates the clinical benefit of magnetic resonance-transrectal ultrasound (MR-TRUS) fusion biopsy over systematic biopsy between first-time and repeat prostate biopsy patients with prior atypical small acinar proliferation (ASAP).MATERIALS: 100 patients were enrolled in a single-centre prospective...

Showing 13 to 24 of 166 entries