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Showing 169 to 177 of 177 entries
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Emotion recognition from multimodal physiological measurements based on an interpretable feature selection method.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Polo EM, Mollura M, Lenatti M, Zanet M, Paglialonga A, Barbieri R.
PMID: 34891454
Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:989-992. doi: 10.1109/EMBC46164.2021.9631019.

Many studies in literature successfully use classification algorithms to classify emotions by means of physiological signals. However, there are still important limitations in interpretability of the results, i.e. lack of feature specific characterizations for each emotional state. To this...

Phase II consolidation trial with anti-Lewis-Y monoclonal antibody (hu3S193) in platinum-sensitive ovarian cancer after a second remission.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Smaletz O, Ismael G, Del Pilar Estevez-Diz M, Nascimento ILO, de Morais ALG, Cunha-Junior GF, Azevedo SJ, Alves VA, Moro AM, Yeda FP, Dos Santos ML, Majumder I, Hoffman EW.
PMID: 33664128
Int J Gynecol Cancer. 2021 Apr;31(4):562-568. doi: 10.1136/ijgc-2020-002239. Epub 2021 Mar 04.

OBJECTIVE: To investigate the efficacy and safety of hu3S193, a humanized anti-Lewis-Y monoclonal antibody, as a consolidation strategy in patients with platinum-sensitive recurrent epithelial ovarian cancer who achieved a second complete response after salvage platinum-doublet chemotherapy.METHODS: This single-arm phase...

Editor's Note: Targeted Gene Silencing Using RGD-Labeled Chitosan Nanoparticles.

Clinical cancer research : an official journal of the American Association for Cancer Research

Han HD, Mangala LS, Lee JW, Shahzad MMK, Kim HS, Shen D, Nam EJ, Mora EM, Stone RL, Lu C, Lee SJ, Roh JW, Nick AM, Lopez-Berestein G, Sood AK.
PMID: 34341058
Clin Cancer Res. 2021 Aug 01;27(15):4453. doi: 10.1158/1078-0432.CCR-21-2119.

No abstract available.

Development of an Orthotopic Murine Model of Rectal Cancer in Conjunction With Targeted Short-Course Radiation Therapy.

Advances in radiation oncology

Uccello TP, Kintzel SA, Mills BN, Murphy JD, Garrett-Larsen J, Battaglia NG, Rodriguez CJ, Drage MG, Ye J, Love TMT, Johnston CJ, Repasky EA, Qiu H, Linehan DC, Lord EM, Gerber SA.
PMID: 35036637
Adv Radiat Oncol. 2021 Dec 09;7(2):100867. doi: 10.1016/j.adro.2021.100867. eCollection 2022.

PURPOSE: Orthotopic tumors more closely recapitulate human cancers than do ectopic models; however, precision targeting of such internal tumors for radiation therapy (RT) without inducing systemic toxicity remains a barrier. We developed an innovative murine orthotopic rectal tumor model...

Low expression of ZHX1 and ZHX2 impacts on the prognosis of chronic lymphocytic leukemia.

Biomarker research

Maciel NIG, Filiú-Braga LDC, Neves FAR, Rego EM, Lucena-Araujo AR, Saldanha-Araujo F.
PMID: 33541423
Biomark Res. 2021 Feb 04;9(1):10. doi: 10.1186/s40364-021-00263-2.

Experimental evidence points to the role of Zinc fingers and homeoboxes protein 1 and 2 (ZHX1 and ZHX2) in the development and progression of several types of cancer, including hematological malignancies. Here, we determined whether the altered expression of...

Modulation of the Human Pancreatic Ductal Adenocarcinoma Immune Microenvironment by Stereotactic Body Radiotherapy.

Clinical cancer research : an official journal of the American Association for Cancer Research

Mills BN, Qiu H, Drage MG, Chen C, Mathew JS, Garrett-Larsen J, Ye J, Uccello TP, Murphy JD, Belt BA, Lord EM, Katz AW, Linehan DC, Gerber SA.
PMID: 34862242
Clin Cancer Res. 2022 Jan 01;28(1):150-162. doi: 10.1158/1078-0432.CCR-21-2495. Epub 2021 Dec 03.

PURPOSE: Stereotactic body radiotherapy (SBRT) is an emerging treatment modality for pancreatic ductal adenocarcinoma (PDAC), which can effectively prime cytotoxic T cells by inducing immunogenic tumor cell death in preclinical models. SBRT effects on human PDAC have yet to...

Covid-19 vaccination during the third trimester of pregnancy: rate of vaccination and maternal and neonatal outcomes, a multicentre retrospective cohort study.

BJOG : an international journal of obstetrics and gynaecology

Rottenstreich M, Sela HY, Rotem R, Kadish E, Wiener-Well Y, Grisaru-Granovsky S.
PMID: 34554630
BJOG. 2022 Jan;129(2):248-255. doi: 10.1111/1471-0528.16941. Epub 2021 Oct 06.

OBJECTIVE: To evaluate the impact of Covid-19 vaccination (Pfizer-BioNTech BNT162b2) during the third trimester of pregnancy on maternal and neonatal outcomes.DESIGN: A multicentre, retrospective computerised database.POPULATION: Women who gave birth at >24 weeks of gestation in Israel, between January...

Silencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression.

Circulation research

Schlegel M, Sharma M, Brown EJ, Newman AAC, Cyr Y, Afonso MS, Corr EM, Koelwyn GJ, van Solingen C, Guzman J, Farhat R, Nikain CA, Shanley LC, Peled D, Schmidt AM, Fisher EA, Moore KJ.
PMID: 34289717
Circ Res. 2021 Aug 20;129(5):530-546. doi: 10.1161/CIRCRESAHA.121.319313. Epub 2021 Jul 22.

[Figure: see text].

Surface Chemical Functionalization of Wrinkled Thiol-ene Elastomers for Promoting Cellular Alignment.

ACS applied bio materials

Ma SJ, Ford EM, Sawicki LA, Sutherland BP, Halaszynski NI, Carberry BJ, Wagner NJ, Kloxin AM, Kloxin CJ.
PMID: 34322660
ACS Appl Bio Mater. 2020 Jun 15;3(6):3731-3740. doi: 10.1021/acsabm.0c00346. Epub 2020 May 19.

Wrinkled polymer surfaces find broad applicability; however, the polymer substrates are often limited to poly(dimethylsiloxane) (PDMS), which limits spatial control over wrinkle features and surface chemistry. An approach to surface functionalization of wrinkled elastomer substrates is demonstrated through versatile,...

Showing 169 to 177 of 177 entries