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Showing 337 to 346 of 346 entries
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The critical role of the aldehyde dehydrogenase PauC in spermine, spermidine, and diaminopropane toxicity in Pseudomonas aeruginosa: Its possible use as a drug target.

The FEBS journal

Cardona-Cardona YV, Regla I, Juárez-Díaz JA, Carrillo-Campos J, López-Ortiz M, Aguilera-Cruz A, Mújica-Jiménez C, Muñoz-Clares RA.
PMID: 34767295
FEBS J. 2021 Nov 12; doi: 10.1111/febs.16277. Epub 2021 Nov 12.

The opportunistic human pathogen Pseudomonas aeruginosa exhibits great resistance to antibiotics; so, new therapeutic agents are urgently needed. Since polyamines levels are incremented in infected tissues, we explored whether the formation of a toxic aldehyde in polyamines degradation can...

The Role of the Non-Collagenous Extracellular Matrix in Tendon and Ligament Mechanical Behavior: A Review.

Journal of biomechanical engineering

Eisner LE, Rosario R, Andarawis-Puri N, Arruda EM.
PMID: 34802057
J Biomech Eng. 2021 Nov 21; doi: 10.1115/1.4053086. Epub 2021 Nov 21.

Tendon is a connective tissue that transmits loads from muscle to bone, while ligament is a similar tissue that stabilizes joint articulation by connecting bone to bone. 70-90% of tendon and ligament's extracellular matrix (ECM) is composed of a...

A Non-Coding RNA Network Involved in KSHV Tumorigenesis.

Frontiers in oncology

Naipauer J, García Solá ME, Salyakina D, Rosario S, Williams S, Coso O, Abba MC, Mesri EA, Lacunza E.
PMID: 34222014
Front Oncol. 2021 Jun 16;11:687629. doi: 10.3389/fonc.2021.687629. eCollection 2021.

Regulatory pathways involving non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and long non-coding RNAs (lncRNA), have gained great relevance due to their role in the control of gene expression modulation. Using RNA sequencing of KSHV Bac36 transfected mouse endothelial...

Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson's disease.

Cell reports

Rosario D, Bidkhori G, Lee S, Bedarf J, Hildebrand F, Le Chatelier E, Uhlen M, Ehrlich SD, Proctor G, Wüllner U, Mardinoglu A, Shoaie S.
PMID: 33657381
Cell Rep. 2021 Mar 02;34(9):108807. doi: 10.1016/j.celrep.2021.108807.

Parkinson's disease (PD) is the most common progressive neurological disorder compromising motor functions. However, nonmotor symptoms, such as gastrointestinal (GI) dysfunction, precede those affecting movement. Evidence of an early involvement of the GI tract and enteric nervous system highlights...

Why Me? To Be an Ultra-Responder to Antiplatelet Therapy: A Case Report.

Frontiers in neurology

Rosafio F, Bigliardi G, Lelli N, Vandelli L, Naldi F, Ciolli L, Meletti S, Zini A.
PMID: 34447344
Front Neurol. 2021 Aug 10;12:663308. doi: 10.3389/fneur.2021.663308. eCollection 2021.

No abstract available.

Exercise Capacity in Young Adults Born Small for Gestational Age.

JAMA cardiology

Crispi F, Rodríguez-López M, Bernardino G, Sepúlveda-Martínez Á, Prat-González S, Pajuelo C, Perea RJ, Caralt MT, Casu G, Vellvé K, Crovetto F, Burgos F, De Craene M, Butakoff C, González Ballester MÁ, Blanco I, Sitges M, Bijnens B, Gratacós E.
PMID: 34287644
JAMA Cardiol. 2021 Nov 01;6(11):1308-1316. doi: 10.1001/jamacardio.2021.2537.

IMPORTANCE: Being born small for gestational age (SGA), approximately 10% of all births, is associated with increased risk of cardiovascular mortality in adulthood, but mechanistic pathways are unclear. Cardiac remodeling and dysfunction occur in fetuses SGA and children born...

The Role of the Non-Collagenous Extracellular Matrix in Tendon and Ligament Mechanical Behavior: A Review.

Journal of biomechanical engineering

Eisner LE, Rosario R, Andarawis-Puri N, Arruda EM.
PMID: 34802057
J Biomech Eng. 2022 May 01;144(5). doi: 10.1115/1.4053086.

Tendon is a connective tissue that transmits loads from muscle to bone, while ligament is a similar tissue that stabilizes joint articulation by connecting bone to bone. The 70-90% of tendon and ligament's extracellular matrix (ECM) is composed of...

Replacement of an endocarditic bioprosthetic pulmonary valve with a monocusp cryopreserved pulmonary artery patch.

JTCVS techniques

García-Rinaldi R, Becerra-Román I, Rosario C, Olmeda S, Reyes-Torres P.
PMID: 34318146
JTCVS Tech. 2021 Jan 13;6:68-70. doi: 10.1016/j.xjtc.2021.01.009. eCollection 2021 Apr.

No abstract available.

Incidence and causes of neonatal hyperbilirubinemia in a center of Catania.

Therapeutics and clinical risk management

Sciuto M, Bertino G, Zocco M, Vecchio I, Raffaele R, Trifiletti RR, Pavone P.
PMID: 19436609
Ther Clin Risk Manag. 2009 Feb;5(1):247-50. doi: 10.2147/tcrm.s4509. Epub 2009 Mar 26.

AIM AND SCOPE: We conducted this study to estimate the incidence of hyperbilirubinemia in a small neonatal care unit in Catania, Italy, and to determine the underlying causes, which would be of value in identifying and implementing strategies to...

Efficacy and Safety of Subcutaneous Vedolizumab in Patients With Moderately to Severely Active Crohn's Disease: Results From the VISIBLE 2 Randomised Trial.

Journal of Crohn's & colitis

Vermeire S, D'Haens G, Baert F, Danese S, Kobayashi T, Loftus EV, Bhatia S, Agboton C, Rosario M, Chen C, Zhang W, Kisfalvi K, Sandborn WJ.
PMID: 34402887
J Crohns Colitis. 2021 Aug 17; doi: 10.1093/ecco-jcc/jjab133. Epub 2021 Aug 17.

BACKGROUND AND AIMS: Report results from VISIBLE 2, a randomised, double-blind, placebo-controlled phase 3 trial evaluating a new subcutaneous [SC] vedolizumab formulation as maintenance treatment in adults with moderately to severely active Crohn's disease [CD].METHODS: Following open-label vedolizumab 300...

Showing 337 to 346 of 346 entries