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Using quantitative reconstitution to investigate multicomponent condensates.

RNA (New York, N.Y.)

Currie SL, Rosen MK.
PMID: 34772789
RNA. 2022 Jan;28(1):27-35. doi: 10.1261/rna.079008.121. Epub 2021 Nov 12.

Many biomolecular condensates are thought to form via liquid-liquid phase separation (LLPS) of multivalent macromolecules. For those that form through this mechanism, our understanding has benefitted significantly from biochemical reconstitutions of key components and activities. Reconstitutions of RNA-based condensates...

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Currie SL, Rosen MK. Using quantitative reconstitution to investigate multicomponent condensates. RNA. 2021;28(1):27-35doi: 10.1261/rna.079008.121.
Currie, S. L., & Rosen, M. K. (2022). Using quantitative reconstitution to investigate multicomponent condensates. RNA (New York, N.Y.), 28(1), 27-35. https://doi.org/10.1261/rna.079008.121
Currie, Simon L, and Rosen, Michael K. "Using quantitative reconstitution to investigate multicomponent condensates." RNA (New York, N.Y.) vol. 28,1 (2022): 27-35. doi: https://doi.org/10.1261/rna.079008.121
Currie SL, Rosen MK. Using quantitative reconstitution to investigate multicomponent condensates. RNA. 2022 Jan;28(1):27-35. doi: 10.1261/rna.079008.121. Epub 2021 Nov 12. PMID: 34772789; PMCID: PMC8675290.
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Crystal structure of 2,2'-{[(2-nitro-benz-yl)aza-nedi-yl]bis-(propane-3,1-di-yl)}bis-[1.

Acta crystallographica. Section E, Crystallographic communications

Holmberg R, Franz V, Moser KM, Solano R, Moore C, Rheingold AL, Smith GLN.
PMID: 33614130
Acta Crystallogr E Crystallogr Commun. 2021 Jan 08;77:83-85. doi: 10.1107/S2056989020016771. eCollection 2021 Feb 01.

The structure of the title compound, C

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Holmberg R, Franz V, Moser KM, et al. Crystal structure of 2,2'-{[(2-nitro-benz-yl)aza-nedi-yl]bis-(propane-3,1-di-yl)}bis-[1. Acta Crystallogr E Crystallogr Commun. 2021;77:83-85doi: 10.1107/S2056989020016771.
Holmberg, R., Franz, V., Moser, K. M., Solano, R., Moore, C., Rheingold, A. L., & Smith, G. L. N. (2021). Crystal structure of 2,2'-{[(2-nitro-benz-yl)aza-nedi-yl]bis-(propane-3,1-di-yl)}bis-[1. Acta crystallographica. Section E, Crystallographic communications, 7783-85. https://doi.org/10.1107/S2056989020016771
Holmberg, Ryne, et al. "Crystal structure of 2,2'-{[(2-nitro-benz-yl)aza-nedi-yl]bis-(propane-3,1-di-yl)}bis-[1." Acta crystallographica. Section E, Crystallographic communications vol. 77 (2021): 83-85. doi: https://doi.org/10.1107/S2056989020016771
Holmberg R, Franz V, Moser KM, Solano R, Moore C, Rheingold AL, Smith GLN. Crystal structure of 2,2'-{[(2-nitro-benz-yl)aza-nedi-yl]bis-(propane-3,1-di-yl)}bis-[1. Acta Crystallogr E Crystallogr Commun. 2021 Jan 08;77:83-85. doi: 10.1107/S2056989020016771. eCollection 2021 Feb 01. PMID: 33614130; PMCID: PMC7869556.
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Breast cancer heterogeneity through the lens of single-cell analysis and spatial pathologies.

Seminars in cancer biology

Zhao N, Rosen JM.
PMID: 34274486
Semin Cancer Biol. 2021 Jul 16; doi: 10.1016/j.semcancer.2021.07.010. Epub 2021 Jul 16.

Breast cancer ecosystems are composed of complex cell types, including tumor, stromal and immune cells, each of which can assume diverse phenotypes. Both the heterogeneous composition and spatially distinct tumor microenvironment impact breast cancer progression, treatment response and therapeutic...

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Zhao N, Rosen JM. Breast cancer heterogeneity through the lens of single-cell analysis and spatial pathologies. Semin Cancer Biol. 2021;doi: 10.1016/j.semcancer.2021.07.010.
Zhao, N., & Rosen, J. M. (2021). Breast cancer heterogeneity through the lens of single-cell analysis and spatial pathologies. Seminars in cancer biology, . https://doi.org/10.1016/j.semcancer.2021.07.010
Zhao, Na, and Rosen, Jeffrey M. "Breast cancer heterogeneity through the lens of single-cell analysis and spatial pathologies." Seminars in cancer biology vol. (2021). doi: https://doi.org/10.1016/j.semcancer.2021.07.010
Zhao N, Rosen JM. Breast cancer heterogeneity through the lens of single-cell analysis and spatial pathologies. Semin Cancer Biol. 2021 Jul 16; doi: 10.1016/j.semcancer.2021.07.010. Epub 2021 Jul 16. PMID: 34274486; PMCID: PMC8761219.
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Inhibition of CRISPR-Cas12a DNA targeting by nucleosomes and chromatin.

Science advances

Strohkendl I, Saifuddin FA, Gibson BA, Rosen MK, Russell R, Finkelstein IJ.
PMID: 33692102
Sci Adv. 2021 Mar 10;7(11). doi: 10.1126/sciadv.abd6030. Print 2021 Mar.

Genome engineering nucleases must access chromatinized DNA. Here, we investigate how AsCas12a cleaves DNA within human nucleosomes and phase-condensed nucleosome arrays. Using quantitative kinetics approaches, we show that dynamic nucleosome unwrapping regulates target accessibility to Cas12a and determines the...

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Strohkendl I, Saifuddin FA, Gibson BA, et al. Inhibition of CRISPR-Cas12a DNA targeting by nucleosomes and chromatin. Sci Adv. 2021;7(11)doi: 10.1126/sciadv.abd6030.
Strohkendl, I., Saifuddin, F. A., Gibson, B. A., Rosen, M. K., Russell, R., & Finkelstein, I. J. (2021). Inhibition of CRISPR-Cas12a DNA targeting by nucleosomes and chromatin. Science advances, 7(11), . https://doi.org/10.1126/sciadv.abd6030
Strohkendl, Isabel, et al. "Inhibition of CRISPR-Cas12a DNA targeting by nucleosomes and chromatin." Science advances vol. 7,11 (2021). doi: https://doi.org/10.1126/sciadv.abd6030
Strohkendl I, Saifuddin FA, Gibson BA, Rosen MK, Russell R, Finkelstein IJ. Inhibition of CRISPR-Cas12a DNA targeting by nucleosomes and chromatin. Sci Adv. 2021 Mar 10;7(11). doi: 10.1126/sciadv.abd6030. Print 2021 Mar. PMID: 33692102; PMCID: PMC7946368.
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Primary Malignant Melanoma of the Urinary Bladder.

Cureus

Snajdar E, Ajo AR, Rosen K, Miller R, Mohammed S, Gordon C, Pui JC, McIntosh G.
PMID: 33898150
Cureus. 2021 Mar 23;13(3):e14067. doi: 10.7759/cureus.14067.

There are only 30 reported cases of primary malignant melanoma of the bladder in the literature so far. Of those, 17 cases were reported as deceased within three years of presentation. Our case reported here is that of a...

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Snajdar E, Ajo AR, Rosen K, et al. Primary Malignant Melanoma of the Urinary Bladder. Cureus. 2021;13(3):e14067doi: 10.7759/cureus.14067.
Snajdar, E., Ajo, A. R., Rosen, K., Miller, R., Mohammed, S., Gordon, C., Pui, J. C., & McIntosh, G. (2021). Primary Malignant Melanoma of the Urinary Bladder. Cureus, 13(3), e14067. https://doi.org/10.7759/cureus.14067
Snajdar, Elizabeth, et al. "Primary Malignant Melanoma of the Urinary Bladder." Cureus vol. 13,3 (2021): e14067. doi: https://doi.org/10.7759/cureus.14067
Snajdar E, Ajo AR, Rosen K, Miller R, Mohammed S, Gordon C, Pui JC, McIntosh G. Primary Malignant Melanoma of the Urinary Bladder. Cureus. 2021 Mar 23;13(3):e14067. doi: 10.7759/cureus.14067. PMID: 33898150; PMCID: PMC8059675.
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Characteristics of Sexual and Gender Minority Caregivers of People With Dementia.

Journal of aging and health

Anderson JG, Flatt JD, Jabson Tree JM, Gross AL, Rose KM.
PMID: 33998313
J Aging Health. 2021 Dec;33(10):838-851. doi: 10.1177/08982643211014767. Epub 2021 May 16.

No abstract available.

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Anderson JG, Flatt JD, Jabson Tree JM, et al. Characteristics of Sexual and Gender Minority Caregivers of People With Dementia. J Aging Health. 2021;33(10):838-851doi: 10.1177/08982643211014767.
Anderson, J. G., Flatt, J. D., Jabson Tree, J. M., Gross, A. L., & Rose, K. M. (2021). Characteristics of Sexual and Gender Minority Caregivers of People With Dementia. Journal of aging and health, 33(10), 838-851. https://doi.org/10.1177/08982643211014767
Anderson, Joel G, et al. "Characteristics of Sexual and Gender Minority Caregivers of People With Dementia." Journal of aging and health vol. 33,10 (2021): 838-851. doi: https://doi.org/10.1177/08982643211014767
Anderson JG, Flatt JD, Jabson Tree JM, Gross AL, Rose KM. Characteristics of Sexual and Gender Minority Caregivers of People With Dementia. J Aging Health. 2021 Dec;33(10):838-851. doi: 10.1177/08982643211014767. Epub 2021 May 16. PMID: 33998313.
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Methylprednisolone and 60 Days in Hospital Survival in Coronavirus Disease 2019 Pneumonia.

Critical care explorations

Go RC, Shah R, Nyirenda T, Oe Y, Sarfraz K, Panthappattu JJ, Philip L, Bheeman C, Shah N, Shah S, Dar S, Hung S, Rahman W, Im H, Marafelias M, Omidvari K, Pradhan A, Sadikot S, Rose KM, Sperber SJ, Josephs J.
PMID: 34291223
Crit Care Explor. 2021 Jul 19;3(7):e0493. doi: 10.1097/CCE.0000000000000493. eCollection 2021 Jul.

OBJECTIVES: To determine methylprednisolone's dose, duration, and administration from onset of symptoms and association with 60 days in hospital survival of coronavirus disease 2019 pneumonia.DESIGN: Cohort study.SETTING: Thirteen hospitals in New Jersey, United States during March to June 2020.PATIENTS:...

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Go RC, Shah R, Nyirenda T, et al. Methylprednisolone and 60 Days in Hospital Survival in Coronavirus Disease 2019 Pneumonia. Crit Care Explor. 2021;3(7):e0493doi: 10.1097/CCE.0000000000000493.
Go, R. C., Shah, R., Nyirenda, T., Oe, Y., Sarfraz, K., Panthappattu, J. J., Philip, L., Bheeman, C., Shah, N., Shah, S., Dar, S., Hung, S., Rahman, W., Im, H., Marafelias, M., Omidvari, K., Pradhan, A., Sadikot, S., Rose, K. M., Sperber, S. J., & Josephs, J. (2021). Methylprednisolone and 60 Days in Hospital Survival in Coronavirus Disease 2019 Pneumonia. Critical care explorations, 3(7), e0493. https://doi.org/10.1097/CCE.0000000000000493
Go, Ronaldo C, et al. "Methylprednisolone and 60 Days in Hospital Survival in Coronavirus Disease 2019 Pneumonia." Critical care explorations vol. 3,7 (2021): e0493. doi: https://doi.org/10.1097/CCE.0000000000000493
Go RC, Shah R, Nyirenda T, Oe Y, Sarfraz K, Panthappattu JJ, Philip L, Bheeman C, Shah N, Shah S, Dar S, Hung S, Rahman W, Im H, Marafelias M, Omidvari K, Pradhan A, Sadikot S, Rose KM, Sperber SJ, Josephs J. Methylprednisolone and 60 Days in Hospital Survival in Coronavirus Disease 2019 Pneumonia. Crit Care Explor. 2021 Jul 19;3(7):e0493. doi: 10.1097/CCE.0000000000000493. eCollection 2021 Jul. PMID: 34291223; PMCID: PMC8291358.
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Showing 325 to 331 of 331 entries