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Showing 25 to 36 of 217 entries
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Evaluating Residual Cognition in Advanced Cognitive Impairment: The Residual Cognition Assessment.

Dementia and geriatric cognitive disorders

Soli A, Savoldelli G, Rota A, Zonca S, Belotti G, Lazzarini F.
PMID: 34879370
Dement Geriatr Cogn Disord. 2021 Dec 08;1-13. doi: 10.1159/000520322. Epub 2021 Dec 08.

BACKGROUND: In nursing homes, most of the patients with dementia are affected by severe cognitive disorder. Care interventions follow an accurate and recurring multidimensional assessment, including cognitive status. There is still a need to develop new performance-based scales for...

Functional redundancy and stability in a subtidal macroalgal community in the Southwestern Atlantic coast.

Marine environmental research

Lanari M, Horta PA, da Silva Copertino M.
PMID: 34775208
Mar Environ Res. 2021 Nov 04;173:105519. doi: 10.1016/j.marenvres.2021.105519. Epub 2021 Nov 04.

Functional redundancy can stabilize ecological functions as asynchronous fluctuations among functionally similar species may buffer environmental changes. We investigated the temporal dynamics of a subtidal macroalgal community in the warm temperate Southwestern Atlantic coast (SWA) to evaluate whether functional...

Role of Single Nucleotide Variants in .

Diagnostics (Basel, Switzerland)

Lidaka L, Bekere L, Rota A, Isakova J, Lazdane G, Kivite-Urtane A, Dzivite-Krisane I, Kempa I, Dobele Z, Gailite L.
PMID: 34943568
Diagnostics (Basel). 2021 Dec 11;11(12). doi: 10.3390/diagnostics11122327.

BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women, affecting up to 16.6% of reproductive-age women. PCOS symptoms in adolescents comprise oligomenorrhoea/amenorrhoea and biochemical and/or clinical hyperandrogenism. Long-term health risks of PCOS patients include infertility, metabolic...

Corrigendum to "Golden carbon of Sargassum forests revealed as an opportunity for climate change mitigation" [Sci. Total Environ., 729 (2020) Start page - End page/ 138745].

The Science of the total environment

Gouvêa LP, Assis J, Gurgel CFD, Serrão EA, Silveira TCL, Santos R, Duarte CM, Peres LMC, Carvalho VF, Batista M, Bastos E, Sissini MN, Horta PA.
PMID: 33518296
Sci Total Environ. 2021 Apr 15;765:144696. doi: 10.1016/j.scitotenv.2020.144696. Epub 2021 Jan 29.

No abstract available.

Expanding the Nude SCID/CID Phenotype Associated with FOXN1 Homozygous, Compound Heterozygous, or Heterozygous Mutations.

Journal of clinical immunology

Giardino G, Sharapova SO, Ciznar P, Dhalla F, Maragliano L, Radha Rama Devi A, Islamoglu C, Ikinciogullari A, Haskologlu S, Dogu F, Hanna-Wakim R, Dbaibo G, Chou J, Cirillo E, Borzacchiello C, Kreins AY, Worth A, Rota IA, Marques JG, Sayitoglu M, Firtina S, Mahdi M, Geha R, Neven B, Sousa AE, Benfenati F, Hollander GA, Davies EG, Pignata C.
PMID: 33464451
J Clin Immunol. 2021 May;41(4):756-768. doi: 10.1007/s10875-021-00967-y. Epub 2021 Jan 19.

Human nude SCID is a rare autosomal recessive inborn error of immunity (IEI) characterized by congenital athymia, alopecia, and nail dystrophy. Few cases have been reported to date. However, the recent introduction of newborn screening for IEIs and high-throughput...

Plastic waste to fuels by hydrocracking at mild conditions.

Science advances

Liu S, Kots PA, Vance BC, Danielson A, Vlachos DG.
PMID: 33883142
Sci Adv. 2021 Apr 21;7(17). doi: 10.1126/sciadv.abf8283. Print 2021 Apr.

Single-use plastics impose an enormous environmental threat, but their recycling, especially of polyolefins, has been proven challenging. We report a direct method to selectively convert polyolefins to branched, liquid fuels including diesel, jet, and gasoline-range hydrocarbons, with high yield...

Impact of Porous Matrices and Concentration by Lyophilization on Cell-Free Expression.

ACS synthetic biology

Blum SM, Lee MS, Mgboji GE, Funk VL, Beabout K, Harbaugh SV, Roth PA, Liem AT, Miklos AE, Emanuel PA, Walper SA, Chávez JL, Lux MW.
PMID: 33843211
ACS Synth Biol. 2021 May 21;10(5):1116-1131. doi: 10.1021/acssynbio.0c00634. Epub 2021 Apr 12.

Cell-free expression systems have drawn increasing attention as a tool to achieve complex biological functions outside of the cell. Several applications of the technology involve the delivery of functionality to challenging environments, such as field-forward diagnostics or point-of-need manufacturing...

A CRISPR interference platform for selective downregulation of gene expression in .

Applied and environmental microbiology

Takacs CN, Scott M, Chang Y, Kloos ZA, Irnov I, Rosa PA, Liu J, Jacobs-Wagner C.
PMID: 33257311
Appl Environ Microbiol. 2020 Nov 30; doi: 10.1128/AEM.02519-20. Epub 2020 Nov 30.

The spirochete

Three decades of clinical trials on immunotherapy for human leishmaniases: a systematic review and meta-analysis.

Immunotherapy

Mota CA, Oyama J, Souza Terron Monich M, Brustolin AÁ, Perez de Souza JV, Murase LS, Ghiraldi Lopes LD, Silva Santos TD, Vieira Teixeira JJ, Verzignassi Silveira TG.
PMID: 33853344
Immunotherapy. 2021 Jun;13(8):693-721. doi: 10.2217/imt-2020-0184. Epub 2021 Apr 15.

No abstract available.

Targeting HSP90 in malignant gliomas: onalespib as a potential therapeutic.

Translational cancer research

Lomeli N, Bota DA.
PMID: 31840022
Transl Cancer Res. 2018 Apr;7(4):6215-6226. doi: 10.21037/tcr.2018.03.05.

No abstract available.

Genomic Landscape of Angiosarcoma: A Targeted and Immunotherapy Biomarker Analysis.

Cancers

Espejo-Freire AP, Elliott A, Rosenberg A, Costa PA, Barreto-Coelho P, Jonczak E, D'Amato G, Subhawong T, Arshad J, Diaz-Perez JA, Korn WM, Oberley MJ, Magee D, Dizon D, von Mehren M, Khushman MM, Hussein AM, Leu K, Trent JC.
PMID: 34638300
Cancers (Basel). 2021 Sep 26;13(19). doi: 10.3390/cancers13194816.

We performed a retrospective analysis of angiosarcoma (AS) genomic biomarkers and their associations with the site of origin in a cohort of 143 cases. Primary sites were head and neck (31%), breast (22%), extremity (11%), viscera (20%), skin at...

Effects of neonatal dopaminergic lesion on oral cocaine self-administration in rats: Higher female vulnerability to cocaine consumption.

Pharmacology, biochemistry, and behavior

de Siqueira Umpierrez L, Freese L, Almeida FB, Costa PA, Fernandes PR, Nin MS, de Souza MF, Barros HMT.
PMID: 34942237
Pharmacol Biochem Behav. 2021 Dec 20;212:173315. doi: 10.1016/j.pbb.2021.173315. Epub 2021 Dec 20.

The dopaminergic system is associated with cocaine-seeking behaviors, being influenced by other neurotransmitters such as GABA and deregulated by chronic cocaine self-administration. Administration of 6-hydroxydopamine (6-OHDA) to neonatal rats produces a depletion of brain dopamine, mainly, that results in...

Showing 25 to 36 of 217 entries