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Showing 13 to 24 of 31 entries
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Referral of patients with emotionally unstable personality disorder for specialist psychological therapy: why, when and how?.

BJPsych bulletin

Roughley M, Maguire A, Wood G, Lee T.
PMID: 33504392
BJPsych Bull. 2021 Feb;45(1):52-58. doi: 10.1192/bjb.2020.48.

Although we commonly work with patients with emotionally unstable personality disorder (EUPD) in community mental health teams (CMHTs), only some enter evidence-based psychological therapies. Many patients are not considered ready to engage in specialist treatments and remain in CMHTs...

Glioblastoma: The Weed of the Brain.

Journal of visual communication in medicine

Roberts A, Roughley M, Wilkinson C.
PMID: 35012411
J Vis Commun Med. 2022 Jan 11;1-7. doi: 10.1080/17453054.2021.2010521. Epub 2022 Jan 11.

No abstract available.

Paranoid and Misidentification Subtypes of Psychosis in Dementia.

Neuroscience and biobehavioral reviews

Pearce D, Gould RL, Roughley M, Reynolds G, Ward EV, Bhome R, Reeves S.
PMID: 35032536
Neurosci Biobehav Rev. 2022 Jan 12;104529. doi: 10.1016/j.neubiorev.2022.104529. Epub 2022 Jan 12.

This study aimed to review the neurobiological and neuropsychological correlates of paranoid (persecutory delusions) and misidentification (misidentification delusions and/or hallucinations) subtypes of psychosis in dementia, to establish if they represent distinct subphenotypes. Nine studies were eligible, all included patients...

Metabolic Effects of Angulation, Compression, and Reduced Mobility on Annulus Fibrosis in a Model of Altered Mechanical Environment in Scoliosis.

Spine deformity

Stokes IA, McBride CA, Aronsson DD, Roughley PJ.
PMID: 27927288
Spine Deform. 2013 May;1(3):161-170. doi: 10.1016/j.jspd.2013.02.001. Epub 2013 Jun 06.

STUDY DESIGN: Comparison of disc tissue from rat tails in 6 groups with different mechanical conditions imposed.OBJECTIVES: To identify disc annulus changes associated with the supposed altered biomechanical environment in a spine with scoliosis deformity using an immature rat...

The atomic structure of niobium and tantalum containing borophosphate glasses.

Journal of physics. Condensed matter : an Institute of Physics journal

Wetherall KM, Doughty P, Mountjoy G, Bettinelli M, Speghini A, Casula MF, Cesare-Marincola F, Locci E, Newport RJ.
PMID: 21832337
J Phys Condens Matter. 2009 Sep 16;21(37):375106. doi: 10.1088/0953-8984/21/37/375106. Epub 2009 Aug 17.

A complete structural study has been carried out on sodium borophosphate glass containing increasing amounts of either niobium or tantalum. A combination of high energy x-ray diffraction, neutron diffraction, extended x-ray absorption fine structure, nuclear magnetic resonance, and infrared...

Development of a whole disc organ culture system to study human intervertebral disc.

Evidence-based spine-care journal

Parolin M, Gawri R, Mwale F, Steffen T, Roughley P, Antoniou J, Jarzem P, Haglund L, Ouellet J.
PMID: 23637672
Evid Based Spine Care J. 2010 Aug;1(2):67-8. doi: 10.1055/s-0028-1100919.

STUDY TYPE:  Basic science Objective:  Low back pain is one of the most common health problems1 and is strongly associated with intervertebral disc degeneration, (IVD). Current treatments remove the symptoms without reversing or even retarding the underlying problem. Development...

The role of aggrecan in normal and osteoarthritic cartilage.

Journal of experimental orthopaedics

Roughley PJ, Mort JS.
PMID: 26914753
J Exp Orthop. 2014 Dec;1(1):8. doi: 10.1186/s40634-014-0008-7. Epub 2014 Jul 16.

Aggrecan is a large proteoglycan bearing numerous chondroitin sulfate and keratan sulfate chains that endow articular cartilage with its ability to withstand compressive loads. It is present in the extracellular matrix in the form of proteoglycan aggregates, in which...

Conspicuously concealed: revision of the arid clade of the .

PeerJ

Kealley L, Doughty P, Pepper M, Keogh JS, Hillyer M, Huey J.
PMID: 30038877
PeerJ. 2018 Jul 19;6:e5334. doi: 10.7717/peerj.5334. eCollection 2018.

The methods used to detect and describe morphologically cryptic species have advanced in recent years, owing to the integrative nature of molecular and morphological techniques required to elucidate them. Here we integrate recent phylogenomic work that sequenced many genes...

INTERACTIVE EFFECTS OF OFFSPRING SIZE AND TIMING OF REPRODUCTION ON OFFSPRING REPRODUCTION: EXPERIMENTAL, MATERNAL, AND QUANTITATIVE GENETIC ASPECTS.

Evolution; international journal of organic evolution

Sinervo B, Doughty P.
PMID: 28565283
Evolution. 1996 Jun;50(3):1314-1327. doi: 10.1111/j.1558-5646.1996.tb02371.x.

We demonstrate that egg size in side-blotched lizards is heritable (parent-offspring regressions) and thus will respond to natural selection. Because our estimate of heritability is derived from free-ranging lizards, it is useful for predicting evolutionary response to selection in...

Detecting life history trade-offs: measuring energy stores in "capital" breeders reveals costs of reproduction.

Oecologia

Doughty P, Shine R.
PMID: 28307242
Oecologia. 1997 May;110(4):508-513. doi: 10.1007/s004420050187.

Life history trade-offs should be detectable as negative correlations between the relevant traits (e.g. reproductive output versus energy storage), but may be masked by variation in resource levels among individuals. One way to detect underlying trade-offs, at least in...

DNA barcode accumulation curves for understudied taxa and areas.

Molecular ecology resources

Smith MA, Fernandez-Triana J, Roughley R, Hebert PD.
PMID: 21564980
Mol Ecol Resour. 2009 May;9:208-16. doi: 10.1111/j.1755-0998.2009.02646.x.

Frequently, the diversity of umbrella taxa is invoked to predict patterns of other, less well-known, life. However, the utility of this strategy has been questioned. We tested whether a phylogenetic diversity (PD) analysis of CO1 DNA barcodes could act...

Loss of Hierarchical Control by Occasion Setters Following Lesions of the Prelimbic and Infralimbic Medial Prefrontal Cortex in Rats.

Brain sciences

Roughley S, Killcross S.
PMID: 30813649
Brain Sci. 2019 Feb 26;9(3). doi: 10.3390/brainsci9030048.

Recent work suggests complementary roles of the prelimbic and infralimbic regions of the rat medial prefrontal cortex in cognitive control processes, with the prelimbic cortex implicated in top-down modulation of associations and the infralimbic cortex playing a role in...

Showing 13 to 24 of 31 entries