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Showing 313 to 323 of 323 entries
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Dissecting the Role of the Ascyrus Medical Dissection Stent.

The Annals of thoracic surgery

Bozso SJ, Moon MC.
PMID: 33971170
Ann Thorac Surg. 2022 Feb;113(2):696-697. doi: 10.1016/j.athoracsur.2021.04.077. Epub 2021 May 08.

No abstract available.

Computational approaches to understanding Clostridioides difficile metabolism and virulence.

Current opinion in microbiology

Jenior ML, Papin JA.
PMID: 34839237
Curr Opin Microbiol. 2021 Nov 25;65:108-115. doi: 10.1016/j.mib.2021.11.002. Epub 2021 Nov 25.

The progress of infection by Clostridioides difficile is strongly influenced by metabolic cues it encounters as it colonizes the gastrointestinal tract. Both colonization and regulation of virulence have a multi-factorial interaction between host, microbiome, and gene expression cascades. While...

Circulating miR-122 in patients with non-toxic acute acetaminophen ingestions.

Clinical toxicology (Philadelphia, Pa.)

Lebin JA, Mudan A, Zhang Y, Wu AHB, Smollin CG.
PMID: 34528842
Clin Toxicol (Phila). 2021 Sep 16;1-3. doi: 10.1080/15563650.2021.1978477. Epub 2021 Sep 16.

No abstract available.

SWI/SNF Complex Mutations Promote Thyroid Tumor Progression and Insensitivity to Redifferentiation Therapies.

Cancer discovery

Saqcena M, Leandro-Garcia LJ, Maag JLV, Tchekmedyian V, Krishnamoorthy GP, Tamarapu PP, Tiedje V, Reuter V, Knauf JA, de Stanchina E, Xu B, Liao XH, Refetoff S, Ghossein R, Chi P, Ho AL, Koche RP, Fagin JA.
PMID: 33318036
Cancer Discov. 2021 May;11(5):1158-1175. doi: 10.1158/2159-8290.CD-20-0735. Epub 2020 Dec 14.

Mutations of subunits of the SWI/SNF chromatin remodeling complexes occur commonly in cancers of different lineages, including advanced thyroid cancers. Here we show that thyroid-specific loss of

Genomic and Transcriptomic Correlates of Thyroid Carcinoma Evolution after BRAF Inhibitor Therapy.

Molecular cancer research : MCR

Lee M, Untch BR, Xu B, Ghossein R, Han C, Kuo F, Valero C, Nadeem Z, Patel N, Makarov V, Dogan S, Wong RJ, Sherman EJ, Ho AL, Chan TA, Fagin JA, Morris LGT.
PMID: 34635506
Mol Cancer Res. 2022 Jan;20(1):45-55. doi: 10.1158/1541-7786.MCR-21-0442. Epub 2021 Oct 11.

Targeted inhibition of BRAF V600E achieves tumor control in a subset of advanced thyroid tumors. Nearly all tumors develop resistance, and some have been observed to subsequently undergo dedifferentiation. The molecular alterations associated with thyroid cancer dedifferentiation in the...

Association between health-related quality of life and menopausal status and symptoms in women living with HIV aged 45-60 years in England: An analysis of the PRIME study.

Women's health (London, England)

Okhai H, Dragomir L, Pool ER, Sabin CA, Miners A, Sherr L, Haag K, Dhairyawan R, Vora N, Sultan B, Gilson R, Burns F, Gilleece Y, Jones R, Post F, Ross J, Ustianowski A, Tariq S.
PMID: 35023404
Womens Health (Lond). 2022 Jan-Dec;18:17455065211068722. doi: 10.1177/17455065211068722.

OBJECTIVES: The aim of this study was to compare the health-related quality of life between mid-life women with HIV and the general population and to investigate the association between health-related quality of life and menopausal (1) status and (2)...

Preoperative activity levels are an important indicator of postoperative activity in cementless TKAs.

Journal of orthopaedics

Dubin JA, Westrich GH.
PMID: 33299273
J Orthop. 2020 Nov 17;22:602-605. doi: 10.1016/j.jor.2020.11.013. eCollection 2020.

INTRODUCTION: It is of interest if preoperative activity level has an impact on postoperative activity level following cementless TKA.METHODS: This review contained 127 patients who had a preoperative Lower Extremity Activity Scale (LEAS) score ≥ to 10 (active patients)...

Removal of Organic Films From Rotating Disks Using Aqueous Solutions of Nonionic Surfactants: Effect of Surfactant Molecular Structure.

Journal of colloid and interface science

Kabin JA, Tolstedt SL, Sáez AE, Grant CS, Carbonell RG.
PMID: 9761633
J Colloid Interface Sci. 1998 Oct 01;206(1):102-111. doi: 10.1006/jcis.1998.5689.

In prior work, we examined the removal of abietic acid films from rotating fiberglass laminate disks by aqueous solutions of a nonionic surfactant. A three-stage cleaning mechanism was found, consisting successively of solubilization, shear-driven cleaning, and roll-up. We extend...

Novel Drivers of Virulence in Clostridioides difficile Identified via Context-Specific Metabolic Network Analysis.

mSystems

Jenior ML, Leslie JL, Powers DA, Garrett EM, Walker KA, Dickenson ME, Petri WA, Tamayo R, Papin JA.
PMID: 34609164
mSystems. 2021 Oct 26;6(5):e0091921. doi: 10.1128/mSystems.00919-21. Epub 2021 Oct 05.

The pathogen Clostridioides difficile causes toxin-mediated diarrhea and is the leading cause of hospital-acquired infection in the United States. Due to growing antibiotic resistance and recurrent infection, targeting C. difficile metabolism presents a new approach to combat this infection....

Intensity-modulated radiation therapy and doxorubicin in thyroid cancer: A prospective phase 2 trial.

Cancer

Romesser PB, Sherman EJ, Whiting K, Ho ML, Shaha AR, Sabra MM, Riaz N, Waldenberg TE, Sabol CR, Ganly I, McBride SM, Fagin JA, Zhang Z, Tuttle RM, Wong RJ, Lee NY.
PMID: 34293201
Cancer. 2021 Nov 15;127(22):4161-4170. doi: 10.1002/cncr.33804. Epub 2021 Jul 22.

BACKGROUND: The use of external-beam radiotherapy for locally advanced nonanaplastic thyroid cancer remains controversial. This prospective study evaluated the efficacy and tolerability of intensity-modulated radiation therapy (IMRT) with or without concurrent chemotherapy in patients with locally advanced thyroid cancer.METHODS:...

The Position of the Heart During Normothermic Ex Situ Heart Perfusion is an Important Factor in Preservation and Recovery of Myocardial Function.

ASAIO journal (American Society for Artificial Internal Organs : 1992)

Hatami S, Qi X, White CW, Bozso SJ, Himmat S, Sergi C, Nagendran J, Chung HJ, Nobes DS, Freed DH.
PMID: 33741785
ASAIO J. 2021 Nov 01;67(11):1222-1231. doi: 10.1097/MAT.0000000000001386.

Ex situ heart perfusion (ESHP) is being investigated as a method for the continuous preservation of the myocardium in a semiphysiologic state for subsequent transplantation. Most methods of ESHP position the isolated heart in a hanging (H) state, representing...

Showing 313 to 323 of 323 entries