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Showing 13 to 24 of 164 entries
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Khellinoflavanone, a Semisynthetic Derivative of Khellin, Overcomes Benzo[.

ACS omega

Sharma R, Williams IS, Gatchie L, Sonawane VR, Chaudhuri B, Bharate SB.
PMID: 31458985
ACS Omega. 2018 Aug 01;3(8):8553-8566. doi: 10.1021/acsomega.8b01088. eCollection 2018 Aug 31.

Cytochrome P450 family 1 (CYP1) enzymes catalyze the metabolic activation of environmental procarcinogens such as benzo[

Discovery of Helminthosporin, an Anthraquinone Isolated from .

ACS omega

Augustin N, Nuthakki VK, Abdullaha M, Hassan QP, Gandhi SG, Bharate SB.
PMID: 32010836
ACS Omega. 2020 Jan 13;5(3):1616-1624. doi: 10.1021/acsomega.9b03693. eCollection 2020 Jan 28.

Natural products have extensively contributed toward the discovery of new leads for Alzheimer's disease. During our search for new inhibitors of cholinesterase enzymes from natural sources, the ethyl acetate (EtOAc) extract of

Nonantioxidant Tetramethoxystilbene Abrogates α-Synuclein-Induced Yeast Cell Death but Not That Triggered by the Bax or βA4 Peptide.

ACS omega

Derf A, Mudududdla R, Akintade D, Williams IS, Abdullaha M, Chaudhuri B, Bharate SB.
PMID: 31459084
ACS Omega. 2018 Aug 20;3(8):9513-9532. doi: 10.1021/acsomega.8b01154. eCollection 2018 Aug 31.

The overexpression of α-synuclein (α-syn) and its aggregation is the hallmark of Parkinson's disease. The α-syn aggregation results in the formation of Lewy bodies that causes neuronal cell death. Therefore, the small molecules that can protect neuronal cells from...

Posterior reversible encephalopathy syndrome associated with SARS-CoV-2 infection.

Journal of neurology, neurosurgery, and psychiatry

Djellaoui A, Seddik L, Cleret De Langavant L, Cattan S, Bachoud-Lévi AC, Hosseini H.
PMID: 32718920
J Neurol Neurosurg Psychiatry. 2020 Jul 27; doi: 10.1136/jnnp-2020-323923. Epub 2020 Jul 27.

No abstract available.

Aberrant splenic artery complicated by aneurysm during pregnancy.

Journal of vascular surgery cases and innovative techniques

Montoya M, Gaddis B, Leoce BM, Dardik H, Bernik TR.
PMID: 29942897
J Vasc Surg Cases Innov Tech. 2018 Apr 27;4(2):119-121. doi: 10.1016/j.jvscit.2018.01.004. eCollection 2018 Jun.

The aberrant splenic artery is an uncommon anomaly. It may become a challenging problem when it is associated with an aneurysm diagnosed during pregnancy. Our experience with a patient who underwent two interventions, each performed in the postpartum period...

Identification of karanjin isolated from the Indian beech tree as a potent CYP1 enzyme inhibitor with cellular efficacy .

MedChemComm

Joshi P, Sonawane VR, Williams IS, McCann GJP, Gatchie L, Sharma R, Satti N, Chaudhuri B, Bharate SB.
PMID: 30108931
Medchemcomm. 2018 Jan 08;9(2):371-382. doi: 10.1039/c7md00388a. eCollection 2018 Feb 01.

CYP1A1 is thought to mediate carcinogenesis in oral, lung and epithelial cancers. In order to identify a CYP1A1 inhibitor from an edible plant, 394 natural products in the IIIM's natural product repository were screened, at 10 μM concentration, using...

Bedside Lung Ultrasound in Emergency Protocol as a Diagnostic Tool in Patients of Acute Respiratory Distress Presenting to Emergency Department.

Journal of emergencies, trauma, and shock

Patel CJ, Bhatt HB, Parikh SN, Jhaveri BN, Puranik JH.
PMID: 29937643
J Emerg Trauma Shock. 2018 Apr-Jun;11(2):125-129. doi: 10.4103/JETS.JETS_21_17.

OBJECTIVE: The objective of this study is to determine the accuracy of the bedside lung ultrasound in emergency (BLUE) protocol in giving a correct diagnosis in patients presenting with acute respiratory distress in emergency department.MATERIALS AND METHODS: Patients with...

Gastrointestinal Myeloid Sarcoma a Case Presentation and Review of the Literature.

Mediterranean journal of hematology and infectious diseases

Kheirkhah P, Avila-Rodriguez AM, Radzik B, Murga-Zamalloa C.
PMID: 34804441
Mediterr J Hematol Infect Dis. 2021 Nov 01;13(1):e2021067. doi: 10.4084/MJHID.2021.067. eCollection 2021.

Myeloid sarcomas can be detected in up to 30% of acute myeloid leukemia cases or occur de-novo without bone marrow involvement. The most frequent localization of myeloid sarcomas in the abdominal cavity is the small intestine, and gastric presentations...

Rh(III)-catalyzed diastereoselective cascade annulation of enone-tethered cyclohexadienones .

Chemical communications (Cambridge, England)

Jadhav SB, Maurya S, Navaneetha N, Chegondi R.
PMID: 34853840
Chem Commun (Camb). 2021 Dec 14;57(99):13598-13601. doi: 10.1039/d1cc05941f.

Herein, we report highly diastereoselective arylative cyclization of enone-tethered cyclohexadienones

Meningitis due to .

Access microbiology

Waris RS, Ballard M, Hong D, Seddik TB.
PMID: 34151165
Access Microbiol. 2021 Mar 10;3(3):000213. doi: 10.1099/acmi.0.000213. eCollection 2021 Mar.

Both bacterial and aseptic meningitis can complicate neurosurgery, but they are often difficult to distinguish clinically or by cerebrospinal fluid (CSF) analysis. We present an adolescent with subacute meningitis after neurosurgery, eventually diagnosed with meningitis caused by

Simultaneous estimation of ZY-19489 and its active metabolite ZY-20486 in human plasma using LC-MS/MS, a novel antimalarial compound.

Bioanalysis

Ghoghari AM, Patel HV, Nayak NN, Mansuri TH, Pillai SM, Jain MR, Patel HB, Kansagra K, Resta ID, Möhrle J, Parmar DV.
PMID: 34779650
Bioanalysis. 2021 Dec;13(23):1761-1777. doi: 10.4155/bio-2021-0194. Epub 2021 Nov 15.

No abstract available.

Prevalence and predictors of Post-Acute COVID-19 Syndrome (PACS) after hospital discharge: A cohort study with 4 months median follow-up.

PloS one

Tleyjeh IM, Saddik B, AlSwaidan N, AlAnazi A, Ramakrishnan RK, Alhazmi D, Aloufi A, AlSumait F, Berbari E, Halwani R.
PMID: 34874962
PLoS One. 2021 Dec 07;16(12):e0260568. doi: 10.1371/journal.pone.0260568. eCollection 2021.

BACKGROUND: Post-acute COVID-19 syndrome (PACS) is an emerging healthcare burden. The risk factors associated with PACS remain largely unclear. The aim of this study was to evaluate the frequency of new or persistent symptoms in COVID-19 patients post hospital...

Showing 13 to 24 of 164 entries