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Showing 253 to 260 of 260 entries
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Synthesis, Characterization and Biological Activity of Some Dithiourea Derivatives.

Acta chimica Slovenica

Odame F, Hosten E, Krause J, Isaacs M, Hoppe H, Khanye SD, Sayed Y, Frost C, Lobb K, Tshentu Z.
PMID: 33533432
Acta Chim Slov. 2020 Sep;67(3):764-777.

Novel dithiourea derivatives have been designed as HIV-1 protease inhibitors using Autodock 4.2, synthesized and characterized by spectroscopic methods and microanalysis. 1-(3-Bromobenzoyl)-3-[2-([(3-bromophenyl)formami-do]methanethioylamino)phenyl]thiourea (10) and 3-benzoyl-1[(phenylformamido)methanethioyl]aminothiourea (12) gave a percentage viability of 17.9 ± 5.6% and 11.2 ± 0.9% against...

Data processing workflow for large-scale immune monitoring studies by mass cytometry.

Computational and structural biotechnology journal

Rybakowska P, Van Gassen S, Quintelier K, Saeys Y, Alarcón-Riquelme ME, Marañón C.
PMID: 34141137
Comput Struct Biotechnol J. 2021 May 21;19:3160-3175. doi: 10.1016/j.csbj.2021.05.032. eCollection 2021.

Mass cytometry is a powerful tool for deep immune monitoring studies. To ensure maximal data quality, a careful experimental and analytical design is required. However even in well-controlled experiments variability caused by either operator or instrument can introduce artifacts...

The RNA Atlas expands the catalog of human non-coding RNAs.

Nature biotechnology

Lorenzi L, Chiu HS, Avila Cobos F, Gross S, Volders PJ, Cannoodt R, Nuytens J, Vanderheyden K, Anckaert J, Lefever S, Tay AP, de Bony EJ, Trypsteen W, Gysens F, Vromman M, Goovaerts T, Hansen TB, Kuersten S, Nijs N, Taghon T, Vermaelen K, Bracke KR, Saeys Y, De Meyer T, Deshpande NP, Anande G, Chen TW, Wilkins MR, Unnikrishnan A, De Preter K, Kjems J, Koster J, Schroth GP, Vandesompele J, Sumazin P, Mestdagh P.
PMID: 34140680
Nat Biotechnol. 2021 Nov;39(11):1453-1465. doi: 10.1038/s41587-021-00936-1. Epub 2021 Jun 17.

Existing compendia of non-coding RNA (ncRNA) are incomplete, in part because they are derived almost exclusively from small and polyadenylated RNAs. Here we present a more comprehensive atlas of the human transcriptome, which includes small and polyA RNA as...

Using a Learning Health System to Improve Physical Therapy Care for Patients with Intermittent Claudication: Lessons Learned from the ClaudicatioNet Quality System.

Physical therapy

Sinnige A, Spruijt S, Saes M, Van der Wees PJ, Hoogeboom TJ, Teijink JAW.
PMID: 34723323
Phys Ther. 2021 Oct 23; doi: 10.1093/ptj/pzab249. Epub 2021 Oct 23.

Routinely collected outcomes data can be used to improve physical therapy care through benchmarking, personalization, continued education, and treatment optimization. In this article, we describe how we created a nationwide infrastructure to routinely collect data from daily practice and...

Prefrailty: The Relationship Between Daily Activities and Social Participation in Older Persons.

Journal of applied gerontology : the official journal of the Southern Gerontological Society

Costenoble A, Knoop V, Debain A, Vermeiren S, Vella Azzopardi R, Rossi G, Smeys C, Baltazar KD, Bautmans I, Verté D, Gorus E, De Vriendt P.
PMID: 33554735
J Appl Gerontol. 2021 Feb 08;733464821991007. doi: 10.1177/0733464821991007. Epub 2021 Feb 08.

OBJECTIVES: To analyze prefrailty's relationship with limitations in activities of daily living (ADLs) and restrictions in social participation.METHOD: Robust (Fried 0/4; RESULTS: Logistic regression retained age (OR = 1.224; 95% CI = [1.122, 1.335]), sex (OR = 3.818; 95%...

Optimal Routing in Stochastic Networks with Reliability Guarantees.

Proceedings. IEEE Conference on Intelligent Transportation Systems

Zheng W, Thangeda P, Savas Y, Ornik M.
PMID: 35003826
Proc IEEE Conf Intell Transp Syst. 2021;2021. doi: 10.1109/itsc48978.2021.9564444. Epub 2021 Oct 25.

Optimal routing in highly congested street networks where the travel times are often stochastic is a challenging problem with significant practical interest. While most approaches to this problem use minimizing the expected travel time as the sole objective, such...

Structural and Functional Properties of Subsidiary Atrial Pacemakers in a Goat Model of Sinus Node Disease.

Frontiers in physiology

Soattin L, Borbas Z, Caldwell J, Prendergast B, Vohra A, Saeed Y, Hoschtitzky A, Yanni J, Atkinson A, Logantha SJ, Borbas B, Garratt C, Morris GM, Dobrzynski H.
PMID: 33746765
Front Physiol. 2021 Mar 04;12:592229. doi: 10.3389/fphys.2021.592229. eCollection 2021.

BACKGROUND: The sinoatrial/sinus node (SAN) is the primary pacemaker of the heart. In humans, SAN is surrounded by the paranodal area (PNA). Although the PNA function remains debated, it is thought to act as a subsidiary atrial pacemaker (SAP)...

Comparing sensitivity and specificity of pacemaker ID application and cardiac rhythm management device-finder application in identifying cardiac implantable electronic device manufacturer using chest radiograph - An observational study.

Annals of medicine and surgery (2012)

Shams P, Mehdi M, Ali J, Ahmed I, Saadia S, Iqbal S, Hameed Khan A, Saeed Y.
PMID: 34484722
Ann Med Surg (Lond). 2021 Aug 20;69:102741. doi: 10.1016/j.amsu.2021.102741. eCollection 2021 Sep.

BACKGROUND: Smartphone-based applications to identify cardiac implantable electronic devices (CIED) are extremely useful in circumstances, where urgent device interrogation is needed, and a device identification card is not available. Few studies have provided insights regarding the utility of these...

Showing 253 to 260 of 260 entries