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Showing 13 to 24 of 408 entries
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Harnessing Therapeutic Potentials of Statins Using Nanofibrous Carriers.

Bioinorganic chemistry and applications

Ataei M, Roufogalis BD, Kesharwani P, Jamialahmadi T, Sahebkar A.
PMID: 34764991
Bioinorg Chem Appl. 2021 Nov 02;2021:7265505. doi: 10.1155/2021/7265505. eCollection 2021.

Statins are a wide category of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor drugs extensively prescribed for hypercholesterolemia. In fact, many studies showed beneficial effects of these agents on a variety of related illnesses, which include increased atherosclerotic plaque stability, decreased...

Comparative effects of on-pump versus off-pump coronary artery bypass grafting surgery on serum cytokine and chemokine levels.

IUBMB life

Mirhafez SR, Khadem SH, Sahebkar A, Movahedi A, Rahsepar AA, Mirzaie A, Jamialahmadi T, Ferns GA, Ghayour-Mobarhan M.
PMID: 34601812
IUBMB Life. 2021 Dec;73(12):1423-1431. doi: 10.1002/iub.2566. Epub 2021 Oct 15.

Coronary artery bypass grafting (CABG) surgery with two methods (on-pump or off-pump) can be used to rescue individuals with severe coronary artery disease (CAD). Each method might cause an inflammatory response, which can lead to some complications. The aim...

Neuroprotective effects of minocycline on focal cerebral ischemia injury: a systematic review.

Neural regeneration research

Naderi Y, Panahi Y, Barreto GE, Sahebkar A.
PMID: 31719236
Neural Regen Res. 2020 May;15(5):773-782. doi: 10.4103/1673-5374.268898.

To review the neuroprotective effects of minocycline in focal cerebral ischemia in animal models. By searching in the databases of PubMed, ScienceDirect, and Scopus, and considering the inclusion and exclusion criteria of the study. Studies were included if focal...

A systematic review and meta-analysis on the prevalence of antibiotic-resistant .

Journal of food science and technology

Khademi F, Sahebkar A.
PMID: 31749464
J Food Sci Technol. 2019 Dec;56(12):5167-5183. doi: 10.1007/s13197-019-04040-w. Epub 2019 Aug 24.

The aim of this study was to determine the antimicrobial resistance characteristics of

Curcumin supplementation in pediatric patients: A systematic review of current clinical evidence.

Phytotherapy research : PTR

Heidari Z, Daei M, Boozari M, Jamialahmadi T, Sahebkar A.
PMID: 34904764
Phytother Res. 2021 Dec 14; doi: 10.1002/ptr.7350. Epub 2021 Dec 14.

This systematic review was designed to determine the clinical efficacy and safety of curcumin supplementation for pediatric patients based on clinical trials in children. We systematically searched electronic databases including PubMed, EMBASE, Web of Science, and Scopus for all...

Investigation of structural, treatment and clinical characteristics of COVID-19 along with the challenges caused by its prevalence.

Infectious disorders drug targets

Doagooyan M, Alavizadeh SH, Akhtari J, Sahebkar A, Kiade SGH, Kochesfahani PH, Gheybi F.
PMID: 33749564
Infect Disord Drug Targets. 2021 Mar 22; doi: 10.2174/1871526521666210322160038. Epub 2021 Mar 22.

In the late 2019, a report from China was published stating a disease with unknown cause. After that,the outbreak of the COVID-19 caused a pandemic in the world. On March 11, 2020, the outbreak of this virus was reported...

Comparison of the clinical features in open and closed format intensive care units: A systematic review and meta-analysis.

Anaesthesia, critical care & pain medicine

Vahedian-Azimi A, Rahimibashar F, Ashtari S, Guest PC, Sahebkar A.
PMID: 34555538
Anaesth Crit Care Pain Med. 2021 Sep 20;40(6):100950. doi: 10.1016/j.accpm.2021.100950. Epub 2021 Sep 20.

IMPORTANCE: The difference in clinical outcomes between closed and open designs of intensive care units (ICUs) is still an open question.OBJECTIVE: We conducted a systematic review and meta-analysis to compare total mortality, hospital and ICU length of stay (LOS)...

Association of ANGPTL3 polymorphisms with high-density lipoprotein cholesterol uptake capacity in patients with cardiovascular disease.

Journal of clinical laboratory analysis

Aghasizadeh M, Nosrati M, Saberi-Karimian M, Safarian H, Assadian P, Akbarpour E, Sahebkar A, Avan A, Ferns GA, Kazemi T, Miri-Moghaddam E, Ghayour-Mobarhan M.
PMID: 34689370
J Clin Lab Anal. 2021 Dec;35(12):e23980. doi: 10.1002/jcla.23980. Epub 2021 Oct 24.

INTRODUCTION: Previous studies have shown the importance of angiopoietin-like 3 (ANGPTL3) as a modulator of lipid profiles. Cholesterol uptake capacity (CUC) is one means for assessing high-density lipoprotein (HDL) functionality. This study for the first time has investigated the...

A Phase 2 Randomized Controlled Trial of the Efficacy and Safety of Cannabidivarin as Add-on Therapy in Participants with Inadequately Controlled Focal Seizures.

Cannabis and cannabinoid research

Brodie MJ, Czapinski P, Pazdera L, Sander JW, Toledo M, Napoles M, Sahebkar F, Schreiber A.
PMID: 33998885
Cannabis Cannabinoid Res. 2021 Dec;6(6):528-536. doi: 10.1089/can.2020.0075. Epub 2021 Feb 15.

No abstract available.

Anti-Tumor Efficacy of Pyrvinium Pamoate Nanoliposomes in an Experimental Model of Melanoma.

Anti-cancer agents in medicinal chemistry

Hatamipour M, Jaafari MR, Zangui M, Shakour N, Sahebkar A.
PMID: 33596812
Anticancer Agents Med Chem. 2021;21(17):2379-2384. doi: 10.2174/1871520621666210217095627.

BACKGROUND: Pyrvinium Pamoate (PP) is an old drug approved by the FDA for the treatment of pinworm infections. Recently, it has been introduced as an anti-tumor agent, however, low aqueous solubility severely limits its potential effects. In this study,...

High Diagnostic and Prognostic Value of miRNAs Compared with the Carcinoembryonic Antigen as a Traditional Tumor Marker.

Anti-cancer agents in medicinal chemistry

Yaghoubi N, Avval FZ, Khazaei M, Sahebkar A, Aghaee-Bakhtiari SH.
PMID: 34102990
Anticancer Agents Med Chem. 2021 Jun 07; doi: 10.2174/1871520621666210608094908. Epub 2021 Jun 07.

A significant challenge in cancer detection and treatment is early diagnosis and accurate prognosis of the disease that enables effective therapies and interventions to improve the patient's condition. Up to now, many parts of research have tended to focus...

Antidiabetic drugs and oxidized low-density lipoprotein: A review of anti-atherosclerotic mechanisms.

Pharmacological research

Ahmadi A, Panahi Y, Johnston TP, Sahebkar A.
PMID: 34400317
Pharmacol Res. 2021 Oct;172:105819. doi: 10.1016/j.phrs.2021.105819. Epub 2021 Aug 14.

Cardiovascular disease is one of the leading causes of mortality globally. Atherosclerosis is an important step towards different types of cardiovascular disease. The role of oxidized low-density lipoprotein (oxLDL) in the initiation and progression of atherosclerosis has been thoroughly...

Showing 13 to 24 of 408 entries