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Showing 13 to 24 of 25 entries
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The non-specific nature of mental health and structural brain outcomes following childhood trauma.

Psychological medicine

Haidl TK, Hedderich DM, Rosen M, Kaiser N, Seves M, Lichtenstein T, Penzel N, Wenzel J, Kambeitz-Ilankovic L, Ruef A, Popovic D, Schultze-Lutter F, Chisholm K, Upthegrove R, Salokangas RKR, Pantelis C, Meisenzahl E, Wood SJ, Brambilla P, Borgwardt S, Ruhrmann S, Kambeitz J, Koutsouleris N.
PMID: 34225834
Psychol Med. 2021 Jul 06;1-10. doi: 10.1017/S0033291721002439. Epub 2021 Jul 06.

BACKGROUND: Childhood trauma (CT) is associated with an increased risk of mental health disorders; however, it is unknown whether this represents a diagnosis-specific risk factor for specific psychopathology mediated by structural brain changes. Our aim was to explore whether...

Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression.

JAMA psychiatry

Koutsouleris N, Dwyer DB, Degenhardt F, Maj C, Urquijo-Castro MF, Sanfelici R, Popovic D, Oeztuerk O, Haas SS, Weiske J, Ruef A, Kambeitz-Ilankovic L, Antonucci LA, Neufang S, Schmidt-Kraepelin C, Ruhrmann S, Penzel N, Kambeitz J, Haidl TK, Rosen M, Chisholm K, Riecher-Rössler A, Egloff L, Schmidt A, Andreou C, Hietala J, Schirmer T, Romer G, Walger P, Franscini M, Traber-Walker N, Schimmelmann BG, Flückiger R, Michel C, Rössler W, Borisov O, Krawitz PM, Heekeren K, Buechler R, Pantelis C, Falkai P, Salokangas RKR, Lencer R, Bertolino A, Borgwardt S, Noethen M, Brambilla P, Wood SJ, Upthegrove R, Schultze-Lutter F, Theodoridou A, Meisenzahl E.
PMID: 33263726
JAMA Psychiatry. 2021 Feb 01;78(2):195-209. doi: 10.1001/jamapsychiatry.2020.3604.

IMPORTANCE: Diverse models have been developed to predict psychosis in patients with clinical high-risk (CHR) states. Whether prediction can be improved by efficiently combining clinical and biological models and by broadening the risk spectrum to young patients with depressive...

Staging intervention and meeting needs in early psychosis.

World psychiatry : official journal of the World Psychiatric Association (WPA)

Salokangas RK.
PMID: 18836538
World Psychiatry. 2008 Oct;7(3):160-2. doi: 10.1002/j.2051-5545.2008.tb00186.x.

No abstract available.

Effect of childhood adversities on alcohol problems is mainly mediated by depression.

The American journal on addictions

Salokangas RKR, From T, Luutonen S, Salokangas HRW, Hietala J.
PMID: 29766600
Am J Addict. 2018 May 15; doi: 10.1111/ajad.12734. Epub 2018 May 15.

BACKGROUND AND OBJECTIVES: We aimed to study how five childhood adversities and trauma (CAT) core domains: emotional abuse (EmoAb), physical abuse (PhyAb), sexual abuse (SexAb), emotional neglect (EmoNeg), physical neglect (PhyNeg), associate with alcohol problems (APs), and whether there...

Onset Age of Substance Use and Neuropsychological Performance in Hospital Patients.

Clinical neuropsychiatry

Höijer I, Ilonen T, Löyttyniemi E, Salokangas RKR.
PMID: 34909003
Clin Neuropsychiatry. 2020 Oct;17(5):271-280. doi: 10.36131/cnfioritieditore20200502.

OBJECTIVE: Several studies have found neurocognitive deficits in adolescents following substance abuse. Predisposing risk factors may further impact vulnerability to neurocognitive deficits. Little is known about the cognitive performance of adult onset substance users compared to earlier onset users....

Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression.

JAMA psychiatry

Koutsouleris N, Dwyer DB, Degenhardt F, Maj C, Urquijo-Castro MF, Sanfelici R, Popovic D, Oeztuerk O, Haas SS, Weiske J, Ruef A, Kambeitz-Ilankovic L, Antonucci LA, Neufang S, Schmidt-Kraepelin C, Ruhrmann S, Penzel N, Kambeitz J, Haidl TK, Rosen M, Chisholm K, Riecher-Rössler A, Egloff L, Schmidt A, Andreou C, Hietala J, Schirmer T, Romer G, Walger P, Franscini M, Traber-Walker N, Schimmelmann BG, Flückiger R, Michel C, Rössler W, Borisov O, Krawitz PM, Heekeren K, Buechler R, Pantelis C, Falkai P, Salokangas RKR, Lencer R, Bertolino A, Borgwardt S, Noethen M, Brambilla P, Wood SJ, Upthegrove R, Schultze-Lutter F, Theodoridou A, Meisenzahl E.
PMID: 33263726
JAMA Psychiatry. 2021 Feb 01;78(2):195-209. doi: 10.1001/jamapsychiatry.2020.3604.

IMPORTANCE: Diverse models have been developed to predict psychosis in patients with clinical high-risk (CHR) states. Whether prediction can be improved by efficiently combining clinical and biological models and by broadening the risk spectrum to young patients with depressive...

Basic Symptoms Are Associated With Age in Patients With a Clinical High-Risk State for Psychosis: Results From the PRONIA Study.

Frontiers in psychiatry

Walger H, Antonucci LA, Pigoni A, Upthegrove R, Salokangas RKR, Lencer R, Chisholm K, Riecher-Rössler A, Haidl T, Meisenzahl E, Rosen M, Ruhrmann S, Kambeitz J, Kambeitz-Ilankovic L, Falkai P, Ruef A, Hietala J, Pantelis C, Wood SJ, Brambilla P, Bertolino A, Borgwardt S, Koutsouleris N, Schultze-Lutter F.
PMID: 33312133
Front Psychiatry. 2020 Nov 17;11:552175. doi: 10.3389/fpsyt.2020.552175. eCollection 2020.

In community studies, both attenuated psychotic symptoms (APS) and basic symptoms (BS) were more frequent but less clinically relevant in children and adolescents compared to adults. In doing so, they displayed differential age thresholds that were around age 16...

Novel Gyrification Networks Reveal Links with Psychiatric Risk Factors in Early Illness.

Cerebral cortex (New York, N.Y. : 1991)

Sanfelici R, Ruef A, Antonucci LA, Penzel N, Sotiras A, Dong MS, Urquijo-Castro M, Wenzel J, Kambeitz-Ilankovic L, Hettwer MD, Ruhrmann S, Chisholm K, Riecher-Rössler A, Falkai P, Pantelis C, Salokangas RKR, Lencer R, Bertolino A, Kambeitz J, Meisenzahl E, Borgwardt S, Brambilla P, Wood SJ, Upthegrove R, Schultze-Lutter F, Koutsouleris N, Dwyer DB.
PMID: 34519351
Cereb Cortex. 2021 Sep 14; doi: 10.1093/cercor/bhab288. Epub 2021 Sep 14.

Adult gyrification provides a window into coordinated early neurodevelopment when disruptions predispose individuals to psychiatric illness. We hypothesized that the echoes of such disruptions should be observed within structural gyrification networks in early psychiatric illness that would demonstrate associations...

Discontinuation of citalopram medication and striatal dopamine activity.

International journal of psychiatry in clinical practice

Salokangas RK, Huttunen J, Hietala J.
PMID: 24941151
Int J Psychiatry Clin Pract. 2006;10(4):300-2. doi: 10.1080/13651500600736692.

A 35-year-old caucasian woman who suffered from major depression with marked psychomotor symptoms was treated with a selective serotonin re-uptake inhibitor (SSRI), citalopram. After 16 months successful treatment, the medication was gradually discontinued. One week after stopping citalopram, she...

The European Prediction of Psychosis Study (EPOS): integrating early recognition and intervention in Europe.

World psychiatry : official journal of the World Psychiatric Association (WPA)

Klosterkötter J, Ruhrmann S, Schultze-Lutter F, Salokangas RK, Linszen D, Birchwood M, Juckel G, Morrison A, Vázquèz-Barquero JL, Hambrecht M, VON Reventlow H.
PMID: 16633542
World Psychiatry. 2005 Oct;4(3):161-7.

This paper provides the rationale and design of the European Prediction of Psychosis Study (EPOS), the first European prospective transnational field study of the prodrome and moderating risk/resilience factors of psychosis. As different health systems provide different structures of...

Increased use of antidepressants in women decreases suicides in men: an ecological study.

The primary care companion for CNS disorders

Salokangas RK, Salminen JK, Korpelainen J, Helenius H, Korkeila J.
PMID: 23106024
Prim Care Companion CNS Disord. 2012;14(3). doi: 10.4088/PCC.11m01256. Epub 2012 May 10.

OBJECTIVE: The suicide rate has decreased in many countries, while the use of antidepressants has increased. In our previous study, the decrease in suicide rate between 1994 and 2001 was greater in men than in women, but the increase...

Short-term functional outcome in psychotic patients: results of the Turku early psychosis study (TEPS).

BMC psychiatry

Salokangas RKR, From T, Ilonen T, Luutonen S, Heinimaa M, Armio RL, Laurikainen H, Walta M, Paju J, Toivonen A, Jalo P, Tuominen L, Hietala J.
PMID: 34856968
BMC Psychiatry. 2021 Dec 02;21(1):602. doi: 10.1186/s12888-021-03516-4.

BACKGROUND: Functional recovery of patients with clinical and subclinical psychosis is associated with clinical, neuropsychological and developmental factors. Less is known about how these factors predict functional outcomes in the same models. We investigated functional outcomes and their predictors...

Showing 13 to 24 of 25 entries