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Showing 145 to 153 of 153 entries
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Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Xiao L, Somers K, Murray J, Pandher R, Karsa M, Ronca E, Bongers A, Terry R, Ehteda A, Gamble LD, Issaeva N, Leonova KI, O'Connor A, Mayoh C, Venkat P, Quek H, Brand J, Kusuma FK, Pettitt JA, Mosmann E, Kearns A, Eden G, Alfred S, Allan S, Zhai L, Kamili A, Gifford AJ, Carter DR, Henderson MJ, Fletcher JI, Marshall G, Johnstone RW, Cesare AJ, Ziegler DS, Gudkov AV, Gurova KV, Norris MD, Haber M.
PMID: 33994371
Clin Cancer Res. 2021 Aug 01;27(15):4338-4352. doi: 10.1158/1078-0432.CCR-20-2357. Epub 2021 May 16.

PURPOSE: We investigated whether targeting chromatin stability through a combination of the curaxin CBL0137 with the histone deacetylase (HDAC) inhibitor, panobinostat, constitutes an effective multimodal treatment for high-risk neuroblastoma.EXPERIMENTAL DESIGN: The effects of the drug combination on cancer growth...

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Xiao L, Somers K, Murray J, et al. Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma. Clin Cancer Res. 2021;27(15):4338-4352doi: 10.1158/1078-0432.CCR-20-2357.
Xiao, L., Somers, K., Murray, J., Pandher, R., Karsa, M., Ronca, E., Bongers, A., Terry, R., Ehteda, A., Gamble, L. D., Issaeva, N., Leonova, K. I., O'Connor, A., Mayoh, C., Venkat, P., Quek, H., Brand, J., Kusuma, F. K., Pettitt, J. A., Mosmann, E., Kearns, A., Eden, G., Alfred, S., Allan, S., Zhai, L., Kamili, A., Gifford, A. J., Carter, D. R., Henderson, M. J., Fletcher, J. I., Marshall, G., Johnstone, R. W., Cesare, A. J., Ziegler, D. S., Gudkov, A. V., Gurova, K. V., Norris, M. D., & Haber, M. (2021). Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 27(15), 4338-4352. https://doi.org/10.1158/1078-0432.CCR-20-2357
Xiao, Lin, et al. "Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma." Clinical cancer research : an official journal of the American Association for Cancer Research vol. 27,15 (2021): 4338-4352. doi: https://doi.org/10.1158/1078-0432.CCR-20-2357
Xiao L, Somers K, Murray J, Pandher R, Karsa M, Ronca E, Bongers A, Terry R, Ehteda A, Gamble LD, Issaeva N, Leonova KI, O'Connor A, Mayoh C, Venkat P, Quek H, Brand J, Kusuma FK, Pettitt JA, Mosmann E, Kearns A, Eden G, Alfred S, Allan S, Zhai L, Kamili A, Gifford AJ, Carter DR, Henderson MJ, Fletcher JI, Marshall G, Johnstone RW, Cesare AJ, Ziegler DS, Gudkov AV, Gurova KV, Norris MD, Haber M. Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma. Clin Cancer Res. 2021 Aug 01;27(15):4338-4352. doi: 10.1158/1078-0432.CCR-20-2357. Epub 2021 May 16. PMID: 33994371; PMCID: PMC8380471.
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Synthetic receptors for logic gated T cell recognition and function.

Current opinion in immunology

Simon S, Bugos G, Salter AI, Riddell SR.
PMID: 34571290
Curr Opin Immunol. 2021 Sep 24;74:9-17. doi: 10.1016/j.coi.2021.09.003. Epub 2021 Sep 24.

Adoptive cell therapy with T cells engineered with customized receptors that redirect antigen specificity to cancer cells has emerged as an effective therapeutic approach for many malignancies. Toxicity due to on target or off target effects, antigen heterogeneity on...

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Simon S, Bugos G, Salter AI, et al. Synthetic receptors for logic gated T cell recognition and function. Curr Opin Immunol. 2021;74:9-17doi: 10.1016/j.coi.2021.09.003.
Simon, S., Bugos, G., Salter, A. I., & Riddell, S. R. (2021). Synthetic receptors for logic gated T cell recognition and function. Current opinion in immunology, 749-17. https://doi.org/10.1016/j.coi.2021.09.003
Simon, Sylvain, et al. "Synthetic receptors for logic gated T cell recognition and function." Current opinion in immunology vol. 74 (2021): 9-17. doi: https://doi.org/10.1016/j.coi.2021.09.003
Simon S, Bugos G, Salter AI, Riddell SR. Synthetic receptors for logic gated T cell recognition and function. Curr Opin Immunol. 2021 Sep 24;74:9-17. doi: 10.1016/j.coi.2021.09.003. Epub 2021 Sep 24. PMID: 34571290.
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Biallelic PI4KA variants cause neurological, intestinal and immunological disease.

Brain : a journal of neurology

Salter CG, Cai Y, Lo B, Helman G, Taylor H, McCartney A, Leslie JS, Accogli A, Zara F, Traverso M, Fasham J, Lees JA, Ferla MP, Chioza BA, Wenger O, Scott E, Cross HE, Crawford J, Warshawsky I, Keisling M, Agamanolis D, Ward Melver C, Cox H, Elawad M, Marton T, Wakeling MN, Holzinger D, Tippelt S, Munteanu M, Valcheva D, Deal C, Van Meerbeke S, Walsh Vockley C, Butte MJ, Acar U, van der Knaap MS, Korenke GC, Kotzaeridou U, Balla T, Simons C, Uhlig HH, Crosby AH, De Camilli P, Wolf NI, Baple EL.
PMID: 34415310
Brain. 2021 Dec 31;144(12):3597-3610. doi: 10.1093/brain/awab313.

Phosphatidylinositol 4-kinase IIIα (PI4KIIIα/PI4KA/OMIM:600286) is a lipid kinase generating phosphatidylinositol 4-phosphate (PI4P), a membrane phospholipid with critical roles in the physiology of multiple cell types. PI4KIIIα's role in PI4P generation requires its assembly into a heterotetrameric complex with EFR3,...

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Salter CG, Cai Y, Lo B, et al. Biallelic PI4KA variants cause neurological, intestinal and immunological disease. Brain. 2021;144(12):3597-3610doi: 10.1093/brain/awab313.
Salter, C. G., Cai, Y., Lo, B., Helman, G., Taylor, H., McCartney, A., Leslie, J. S., Accogli, A., Zara, F., Traverso, M., Fasham, J., Lees, J. A., Ferla, M. P., Chioza, B. A., Wenger, O., Scott, E., Cross, H. E., Crawford, J., Warshawsky, I., Keisling, M., Agamanolis, D., Ward Melver, C., Cox, H., Elawad, M., Marton, T., Wakeling, M. N., Holzinger, D., Tippelt, S., Munteanu, M., Valcheva, D., Deal, C., Van Meerbeke, S., Walsh Vockley, C., Butte, M. J., Acar, U., van der Knaap, M. S., Korenke, G. C., Kotzaeridou, U., Balla, T., Simons, C., Uhlig, H. H., Crosby, A. H., De Camilli, P., Wolf, N. I., & Baple, E. L. (2021). Biallelic PI4KA variants cause neurological, intestinal and immunological disease. Brain : a journal of neurology, 144(12), 3597-3610. https://doi.org/10.1093/brain/awab313
Salter, Claire G, et al. "Biallelic PI4KA variants cause neurological, intestinal and immunological disease." Brain : a journal of neurology vol. 144,12 (2021): 3597-3610. doi: https://doi.org/10.1093/brain/awab313
Salter CG, Cai Y, Lo B, Helman G, Taylor H, McCartney A, Leslie JS, Accogli A, Zara F, Traverso M, Fasham J, Lees JA, Ferla MP, Chioza BA, Wenger O, Scott E, Cross HE, Crawford J, Warshawsky I, Keisling M, Agamanolis D, Ward Melver C, Cox H, Elawad M, Marton T, Wakeling MN, Holzinger D, Tippelt S, Munteanu M, Valcheva D, Deal C, Van Meerbeke S, Walsh Vockley C, Butte MJ, Acar U, van der Knaap MS, Korenke GC, Kotzaeridou U, Balla T, Simons C, Uhlig HH, Crosby AH, De Camilli P, Wolf NI, Baple EL. Biallelic PI4KA variants cause neurological, intestinal and immunological disease. Brain. 2021 Dec 31;144(12):3597-3610. doi: 10.1093/brain/awab313. PMID: 34415310.
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An Investigation of Radiation Treatment Learning Opportunities in Relation to the Radiation Oncology Electronic Medical Record: A Single Institution Experience.

Advances in radiation oncology

Huang YJ, Sarkar V, Paxton A, Zhao H, Su FF, Price R, Salter BJ.
PMID: 34805621
Adv Radiat Oncol. 2021 Sep 29;7(1):100812. doi: 10.1016/j.adro.2021.100812. eCollection 2022.

PURPOSE: A modern radiation oncology electronic medical record (RO-EMR) system represents a sophisticated human-computer interface with the potential to reduce human driven errors and improve patient safety. As the RO-EMR becomes an integral part of clinical processes, it may...

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Huang YJ, Sarkar V, Paxton A, et al. An Investigation of Radiation Treatment Learning Opportunities in Relation to the Radiation Oncology Electronic Medical Record: A Single Institution Experience. Adv Radiat Oncol. 2021;7(1):100812doi: 10.1016/j.adro.2021.100812.
Huang, Y. J., Sarkar, V., Paxton, A., Zhao, H., Su, F. F., Price, R., & Salter, B. J. (2022). An Investigation of Radiation Treatment Learning Opportunities in Relation to the Radiation Oncology Electronic Medical Record: A Single Institution Experience. Advances in radiation oncology, 7(1), 100812. https://doi.org/10.1016/j.adro.2021.100812
Huang, Y Jessica, et al. "An Investigation of Radiation Treatment Learning Opportunities in Relation to the Radiation Oncology Electronic Medical Record: A Single Institution Experience." Advances in radiation oncology vol. 7,1 (2022): 100812. doi: https://doi.org/10.1016/j.adro.2021.100812
Huang YJ, Sarkar V, Paxton A, Zhao H, Su FF, Price R, Salter BJ. An Investigation of Radiation Treatment Learning Opportunities in Relation to the Radiation Oncology Electronic Medical Record: A Single Institution Experience. Adv Radiat Oncol. 2021 Sep 29;7(1):100812. doi: 10.1016/j.adro.2021.100812. eCollection 2022. PMID: 34805621; PMCID: PMC8581278.
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Using the payback framework to evaluate the outcomes of pilot projects supported by the Georgia Clinical and Translational Science Alliance.

Journal of clinical and translational science

Rollins L, Llewellyn N, Ngaiza M, Nehl E, Carter DR, Sands JM.
PMID: 33948270
J Clin Transl Sci. 2020 Sep 11;5(1):e48. doi: 10.1017/cts.2020.542.

INTRODUCTION: The Clinical and Translational Science Awards (CTSA) program of the National Center for Advancing Translational Sciences (NCATS) seeks to improve population health by accelerating the translation of scientific discoveries in the laboratory and clinic into practices for the...

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Rollins L, Llewellyn N, Ngaiza M, et al. Using the payback framework to evaluate the outcomes of pilot projects supported by the Georgia Clinical and Translational Science Alliance. J Clin Transl Sci. 2020;5(1):e48doi: 10.1017/cts.2020.542.
Rollins, L., Llewellyn, N., Ngaiza, M., Nehl, E., Carter, D. R., & Sands, J. M. (2020). Using the payback framework to evaluate the outcomes of pilot projects supported by the Georgia Clinical and Translational Science Alliance. Journal of clinical and translational science, 5(1), e48. https://doi.org/10.1017/cts.2020.542
Rollins, Latrice, et al. "Using the payback framework to evaluate the outcomes of pilot projects supported by the Georgia Clinical and Translational Science Alliance." Journal of clinical and translational science vol. 5,1 (2020): e48. doi: https://doi.org/10.1017/cts.2020.542
Rollins L, Llewellyn N, Ngaiza M, Nehl E, Carter DR, Sands JM. Using the payback framework to evaluate the outcomes of pilot projects supported by the Georgia Clinical and Translational Science Alliance. J Clin Transl Sci. 2020 Sep 11;5(1):e48. doi: 10.1017/cts.2020.542. PMID: 33948270; PMCID: PMC8057435.
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How to improve adolescent mothers' satisfaction with childbirth?.

Journal of pediatric and adolescent gynecology

Nomura RMY, Galter FR, Passarelli VC.
PMID: 34902561
J Pediatr Adolesc Gynecol. 2021 Dec 10; doi: 10.1016/j.jpag.2021.12.004. Epub 2021 Dec 10.

STUDY OBJECTIVE: This study aimed to analyze factors related to adolescent mothers' satisfaction with childbirth.DESIGN: Prospective and cross-sectional study.PARTICIPANTS: Fifty adolescent mothers with maternal age from 14 to 19 years and delivery of a single and live newborn at...

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Nomura RMY, Galter FR, Passarelli VC. How to improve adolescent mothers' satisfaction with childbirth?. J Pediatr Adolesc Gynecol. 2021;doi: 10.1016/j.jpag.2021.12.004.
Nomura, R. M. Y., Galter, F. R., & Passarelli, V. C. (2021). How to improve adolescent mothers' satisfaction with childbirth?. Journal of pediatric and adolescent gynecology, . https://doi.org/10.1016/j.jpag.2021.12.004
Nomura, R M Y, et al. "How to improve adolescent mothers' satisfaction with childbirth?." Journal of pediatric and adolescent gynecology vol. (2021). doi: https://doi.org/10.1016/j.jpag.2021.12.004
Nomura RMY, Galter FR, Passarelli VC. How to improve adolescent mothers' satisfaction with childbirth?. J Pediatr Adolesc Gynecol. 2021 Dec 10; doi: 10.1016/j.jpag.2021.12.004. Epub 2021 Dec 10. PMID: 34902561.
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Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function.

Science signaling

Salter AI, Rajan A, Kennedy JJ, Ivey RG, Shelby SA, Leung I, Templeton ML, Muhunthan V, Voillet V, Sommermeyer D, Whiteaker JR, Gottardo R, Veatch SL, Paulovich AG, Riddell SR.
PMID: 34429382
Sci Signal. 2021 Aug 24;14(697). doi: 10.1126/scisignal.abe2606.

Chimeric antigen receptor (CAR)-modified T cell therapy is effective in treating lymphomas, leukemias, and multiple myeloma in which the tumor cells express high amounts of target antigen. However, achieving durable remission for these hematological malignancies and extending CAR T...

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Salter AI, Rajan A, Kennedy JJ, et al. Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function. Sci Signal. 2021;14(697)doi: 10.1126/scisignal.abe2606.
Salter, A. I., Rajan, A., Kennedy, J. J., Ivey, R. G., Shelby, S. A., Leung, I., Templeton, M. L., Muhunthan, V., Voillet, V., Sommermeyer, D., Whiteaker, J. R., Gottardo, R., Veatch, S. L., Paulovich, A. G., & Riddell, S. R. (2021). Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function. Science signaling, 14(697), . https://doi.org/10.1126/scisignal.abe2606
Salter, Alexander I, et al. "Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function." Science signaling vol. 14,697 (2021). doi: https://doi.org/10.1126/scisignal.abe2606
Salter AI, Rajan A, Kennedy JJ, Ivey RG, Shelby SA, Leung I, Templeton ML, Muhunthan V, Voillet V, Sommermeyer D, Whiteaker JR, Gottardo R, Veatch SL, Paulovich AG, Riddell SR. Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function. Sci Signal. 2021 Aug 24;14(697). doi: 10.1126/scisignal.abe2606. PMID: 34429382; PMCID: PMC8613804.
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Cavity-enhanced Raman spectroscopy with optical feedback cw diode lasers for gas phase analysis and spectroscopy.

The Analyst

Salter R, Chu J, Hippler M.
PMID: 22836382
Analyst. 2012 Oct 21;137(20):4669-76. doi: 10.1039/c2an35722d.

A variant of cavity-enhanced Raman spectroscopy (CERS) is introduced, in which diode laser radiation at 635 nm is coupled into an external linear optical cavity composed of two highly reflective mirrors. Using optical feedback stabilisation, build-up of circulating laser...

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Salter R, Chu J, Hippler M. Cavity-enhanced Raman spectroscopy with optical feedback cw diode lasers for gas phase analysis and spectroscopy. Analyst. 2012;137(20):4669-76doi: 10.1039/c2an35722d.
Salter, R., Chu, J., & Hippler, M. (2012). Cavity-enhanced Raman spectroscopy with optical feedback cw diode lasers for gas phase analysis and spectroscopy. The Analyst, 137(20), 4669-76. https://doi.org/10.1039/c2an35722d
Salter, Robert, et al. "Cavity-enhanced Raman spectroscopy with optical feedback cw diode lasers for gas phase analysis and spectroscopy." The Analyst vol. 137,20 (2012): 4669-76. doi: https://doi.org/10.1039/c2an35722d
Salter R, Chu J, Hippler M. Cavity-enhanced Raman spectroscopy with optical feedback cw diode lasers for gas phase analysis and spectroscopy. Analyst. 2012 Oct 21;137(20):4669-76. doi: 10.1039/c2an35722d. PMID: 22836382.
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Building Bridges to Other Departments: Three Strategies.

Barr V, Liew CW, Salter R.
UIID-AD: 880
2010;64-65.

With the declining interest among incoming college students and the nationwide drop in computer science (CS) enrollments ([2, 1]), many CS departments would like to broaden participation in computing by reaching out to other departments on their campuses. One...

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Barr V, Liew CW, Salter R. Building Bridges to Other Departments: Three Strategies. 2010;64-65
Barr, V., Liew, C. W., & Salter, R. (2010). Building Bridges to Other Departments: Three Strategies. 64-65.
Barr, V, et al. "Building Bridges to Other Departments: Three Strategies." vol. (2010): 64-65.
Barr V, Liew CW, Salter R. Building Bridges to Other Departments: Three Strategies. 2010;64-65. UIID-AD: 880.
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Showing 145 to 153 of 153 entries