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Showing 505 to 515 of 515 entries
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RNA-binding proteins and post-transcriptional regulation in lens biology and cataract: Mediating spatiotemporal expression of key factors that control the cell cycle, transcription, cytoskeleton and transparency.

Experimental eye research

Lachke SA.
PMID: 34906599
Exp Eye Res. 2021 Dec 11;214:108889. doi: 10.1016/j.exer.2021.108889. Epub 2021 Dec 11.

Development of the ocular lens - a transparent tissue capable of sustaining frequent shape changes for optimal focusing power - pushes the boundaries of what cells can achieve using the molecular toolkit encoded by their genomes. The mammalian lens...

RNA-binding proteins and post-transcriptional regulation in lens biology and cataract: Mediating spatiotemporal expression of key factors that control the cell cycle, transcription, cytoskeleton and transparency.

Experimental eye research

Lachke SA.
PMID: 34906599
Exp Eye Res. 2021 Dec 11;214:108889. doi: 10.1016/j.exer.2021.108889. Epub 2021 Dec 11.

Development of the ocular lens - a transparent tissue capable of sustaining frequent shape changes for optimal focusing power - pushes the boundaries of what cells can achieve using the molecular toolkit encoded by their genomes. The mammalian lens...

Comparison of imaging modalities in the diagnosis of external cervical resorption (ECR): an in-vitro study.

Odontology

Cunliffe J, Al-Hadidi A, Sawair FA, Mahasneh SA.
PMID: 34448951
Odontology. 2022 Jan;110(1):157-163. doi: 10.1007/s10266-021-00651-y. Epub 2021 Aug 27.

External cervical resorption is a pathological condition affecting the cervical margins of teeth. Due to the increased prevalence and the area it affects, it can be easily misdiagnosed. The ability of clinicians to diagnose ECR and subcategorise the lesions...

Challenging Assumptions about the Future Supply and Demand of Physical Therapists in the United States.

Physical therapy

Childs JD, Benz LN, Arellano A, Briggs AA, Walker MJ.
PMID: 34662413
Phys Ther. 2021 Oct 15; doi: 10.1093/ptj/pzab239. Epub 2021 Oct 15.

No abstract available.

Silent hypoxia in COVID-19: a gut microbiota connection.

Current opinion in physiology

Gopal AB, Chakraborty S, Padhan PK, Barik A, Dixit P, Chakraborty D, Poirah I, Samal S, Sarkar A, Bhattacharyya A.
PMID: 34250324
Curr Opin Physiol. 2021 Oct;23:100456. doi: 10.1016/j.cophys.2021.06.010. Epub 2021 Jul 06.

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection has triggered the COVID-19 pandemic. Several factors induce hypoxia in COVID-19. Despite being hypoxic, some SARS-CoV-2-infected individuals do not experience any respiratory distress, a phenomenon termed 'silent (or happy) hypoxia'. Prolonged undetected...

Non-cell-autonomous OTX2 transcription factor regulates anxiety-related behavior in the mouse.

Molecular psychiatry

Vincent C, Gilabert-Juan J, Gibel-Russo R, Alvarez-Fischer D, Krebs MO, Le Pen G, Prochiantz A, Di Nardo AA.
PMID: 33963285
Mol Psychiatry. 2021 Nov;26(11):6469-6480. doi: 10.1038/s41380-021-01132-y. Epub 2021 May 07.

The OTX2 homeoprotein transcription factor is expressed in the dopaminergic neurons of the ventral tegmental area, which projects to limbic structures controlling complex behaviors. OTX2 is also produced in choroid plexus epithelium, from which it is secreted into cerebrospinal...

Optimized CRISPR-RfxCas13d system for RNA targeting in zebrafish embryos.

STAR protocols

Hernandez-Huertas L, Kushawah G, Diaz-Moscoso A, Tomas-Gallardo L, Moreno-Sanchez I, da Silva Pescador G, Bazzini AA, Moreno-Mateos MA.
PMID: 35005640
STAR Protoc. 2021 Dec 23;3(1):101058. doi: 10.1016/j.xpro.2021.101058. eCollection 2022 Mar 18.

CRISPR-Cas systems have been used to induce DNA mutagenesis for gene function discovery. However, the development of tools to eliminate RNAs provides complementary and unique approaches to disrupt gene expression. Here, we present a workflow to perform specific, efficient,...

Best Practice Recommendations for Stroke Patients with Dysphagia: A Delphi-Based Consensus Study of Experts in Turkey-Part I: Management, Diagnosis, and Follow-up.

Dysphagia

Umay E, Eyigor S, Ertekin C, Unlu Z, Selcuk B, Bahat G, Karahan AY, Secil Y, Gurcay E, Kıylioglu N, Yavuz Keles B, Giray E, Tikiz C, Albayrak Gezer I, Yalıman A, Sen EI, Vural M, Saylam G, Akaltun MS, Sari A, Alicura S, Karaahmet F, Inanir M, Demirhan A, Aydeniz B, Bilgilisoy M, Yuksel A, Ozcete ZA, Calik Y, Alemdaroglu E, Keskin D, Sahin S, Oztekin MF, Sezgin B, Karaahmet O, Bengisu S, Yalcin Gokler T, Mercimekci S.
PMID: 33687558
Dysphagia. 2021 Mar 09; doi: 10.1007/s00455-021-10273-9. Epub 2021 Mar 09.

Dysphagia is one of the most common and important complications of stroke. It is an independent marker of poor outcome after acute stroke and may become chronic after the acute period and continues to affect all aspects of the...

Expanding and Remixing the Metadata Landscape.

Trends in cancer

Hippen AA, Greene CS.
PMID: 33229213
Trends Cancer. 2021 Apr;7(4):276-278. doi: 10.1016/j.trecan.2020.10.011. Epub 2020 Nov 20.

Genomic data sharing accelerates research. Data are most valuable when they are accompanied by detailed metadata. To date, metadata are often human-annotated descriptions of samples and their handling. We discuss how machine learning-derived elements complement such descriptions to enhance...

Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease.

Bioorganic & medicinal chemistry

Singh YP, Shankar G, Jahan S, Singh G, Kumar N, Barik A, Upadhyay P, Singh L, Kamble K, Singh GK, Tiwari S, Garg P, Gupta S, Modi G.
PMID: 34481338
Bioorg Med Chem. 2021 Sep 15;46:116385. doi: 10.1016/j.bmc.2021.116385. Epub 2021 Aug 28.

In our earlier paper, we described ferulic acid (FA) template based novel series of multifunctional cholinesterase (ChE) inhibitors for the management of AD. This report has further extended the structure-activity relationship (SAR) studies of this series of molecules in...

High prevalence of obstructive sleep apnea in pregnant women with class III obesity: a prospective cohort study.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Johns EC, Hill EA, Stevie WB, Sabil A, Riha RL, Denison FC, Reynolds RM.
PMID: 34351847
J Clin Sleep Med. 2021 Aug 05; doi: 10.5664/jcsm.9578. Epub 2021 Aug 05.

STUDY OBJECTIVES: To determine the prevalence of obstructive sleep apnea (OSA) in a cohort of women with class III obesity, and a comparator lean group, in the second and third trimesters of pregnancy. Secondary objectives were to compare characteristics...

Showing 505 to 515 of 515 entries