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Showing 769 to 779 of 779 entries
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Emerging Role of miR-345 and Its Effective Delivery as a Potential Therapeutic Candidate in Pancreatic Cancer and Other Cancers.

Pharmaceutics

Natesh NS, White BM, Bennett MMC, Uz M, Kalari Kandy RR, Batra SK, Mallapragada SK, Rachagani S.
PMID: 34959269
Pharmaceutics. 2021 Nov 23;13(12). doi: 10.3390/pharmaceutics13121987.

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with high mortality, poor prognosis, and palliative treatments, due to the rapid upregulation of alternative compensatory pathways and desmoplastic reaction. miRNAs, small non-coding RNAs, have been recently identified as key players...

Synergistic Dual-Atom Molecular Catalyst Derived from Low-Temperature Pyrolyzed Heterobimetallic Macrocycle-N4 Corrole Complex for Oxygen Reduction.

Small (Weinheim an der Bergstrasse, Germany)

Samireddi S, Aishwarya V, Shown I, Muthusamy S, Unni SM, Wong KT, Chen KH, Chen LC.
PMID: 34665522
Small. 2021 Nov;17(46):e2103823. doi: 10.1002/smll.202103823. Epub 2021 Oct 19.

A heterobimetallic corrole complex, comprising oxygen reduction reaction (ORR) active non-precious metals Co and Fe with a corrole-N4 center (PhFCC), is successfully synthesized and used to prepare a dual-atom molecular catalyst (DAMC) through subsequent low-temperature pyrolysis. This low-temperature pyrolyzed...

Topical alpha-selective p38 MAP kinase inhibition reduces acute skin inflammation in guinea pig.

Journal of inflammation research

Medicherla S, Ma JY, Reddy M, Esikova I, Kerr I, Movius F, Higgins LS, Protter AA.
PMID: 22096353
J Inflamm Res. 2010;3:9-16. doi: 10.2147/jir.s6718. Epub 2010 Feb 18.

Certain skin pathologies, including psoriasis, are thought to be immune-mediated inflammatory diseases. Available literature clearly indicates the involvement of inflammatory cells (neutrophils, T cells, and macrophages), their cytokines, and the p38 mitogen-activated protein kinase (MAPK) signaling pathway in the...

Prenatal phthalate exposure in relation to placental corticotropin releasing hormone (pCRH) in the CANDLE cohort.

Environment international

Barrett ES, Corsetti M, Day D, Thurston SW, Loftus CT, Karr CJ, Kannan K, LeWinn KZ, Smith AK, Smith R, Tylavsky FA, Bush NR, Sathyanarayana S.
PMID: 35007898
Environ Int. 2022 Jan 07;160:107078. doi: 10.1016/j.envint.2022.107078. Epub 2022 Jan 07.

CONTEXT: Phthalates may disrupt maternal-fetal-placental endocrine pathways, affecting pregnancy outcomes and child development. Placental corticotropin releasing hormone (pCRH) is critical for healthy pregnancy and child development, but understudied as a target of endocrine disruption.OBJECTIVE: To examine phthalate metabolite concentrations...

Synergy between low BMI and hyperglycemia at baseline increases tuberculosis incidence among people living with HIV.

AIDS (London, England)

Kyaw NTT, Kumar AMV, Harries AD, Satyanarayana S, Oo NL, Hayat MJ, Castro KG, Magee MJ.
PMID: 34586087
AIDS. 2022 Jan 01;36(1):117-125. doi: 10.1097/QAD.0000000000003090.

OBJECTIVES: Low BMI and hyperglycemia are each important risk factors for tuberculosis (TB). However, the contribution of synergy between low BMI and hyperglycemia to risk of TB among people living with HIV (PWH) is unexplored. We compared TB incidence...

Amyloid Precursor-like Protein 2 Expression Increases during Pancreatic Cancer Development and Shortens the Survival of a Spontaneous Mouse Model of Pancreatic Cancer.

Cancers

Poelaert BJ, Knoche SM, Larson AC, Pandey P, Seshacharyulu P, Khan N, Maurer HC, Olive KP, Sheinin Y, Ahmad R, Singh AB, Batra SK, Rachagani S, Solheim JC.
PMID: 33810510
Cancers (Basel). 2021 Mar 26;13(7). doi: 10.3390/cancers13071535.

In the United States, pancreatic cancer is a major cause of cancer-related deaths. Although substantial efforts have been made to understand pancreatic cancer biology and improve therapeutic efficacy, patients still face a bleak chance of survival. A greater understanding...

Palladium-Catalyzed Distal .

Organic letters

Srinivas D, Satyanarayana G.
PMID: 34519504
Org Lett. 2021 Oct 01;23(19):7353-7358. doi: 10.1021/acs.orglett.1c02460. Epub 2021 Sep 14.

Herein, we present

Pneumothorax and Pneumomediastinum Secondary to COVID-19 Disease Unrelated to Mechanical Ventilation.

Case reports in critical care

Tucker L, Patel S, Vatsis C, Poma A, Ammar A, Nasser W, Mukkera S, Vo M, Khan R, Carlan S.
PMID: 33299613
Case Rep Crit Care. 2020 Nov 23;2020:6655428. doi: 10.1155/2020/6655428. eCollection 2020.

In the recent worldwide coronavirus 2019 pandemic, a notable rise in pneumomediastinum and pneumothorax complications has been witnessed in numerous mechanically ventilated patients infected with severe acute respiratory syndrome coronavirus 2. Most cases have reported these complications as barotrauma...

Erratum: Melough, M.M.; et al. Dietary Sources of Melamine Exposure among US Children and Adults in the National Health and Nutrition Examination Survey 2003-2004. .

Nutrients

Melough MM, Foster D, Fretts AM, Sathyanarayana S.
PMID: 33809817
Nutrients. 2021 Mar 16;13(3). doi: 10.3390/nu13030958.

The authors have requested that the following changes be made to their paper [...].

Microsecond simulation analysis of carbonic anhydrase - II in complex with (+)-cathechin revealed molecular interactions responsible for its amelioration effect on fluoride toxicity.

Journal of biomolecular structure & dynamics

Yadav PR, Hussain Basha S, Satyanarayana SDV, Pindi PK.
PMID: 33719850
J Biomol Struct Dyn. 2021 Mar 15;1-14. doi: 10.1080/07391102.2021.1898471. Epub 2021 Mar 15.

Fluorosis is a chronic condition caused by overexposure to fluoride, marked by impaired dental, skeletal, and non-skeletal health. In presence of excess fluoride ions, in severe cases calcification of the ligaments observed. Earlier studies have suggested that the disruption...

Utilizing learning communities to deliver an integrated undergraduate medical education curriculum.

Medical education online

Braunreiter C, Sudhanthar S, Riley B, Armstrong K, Mavis B, Gold J.
PMID: 34895116
Med Educ Online. 2022 Dec;27(1):2011606. doi: 10.1080/10872981.2021.2011606.

AIM: Learning communities (LCs) have been identified as a structure to support student wellness as well as create a positive learning environment and have been increasingly adopted in undergraduate medical education (UGME). In 2016, Michigan State University College of...

Showing 769 to 779 of 779 entries