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Showing 13 to 24 of 209 entries
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Minimally Invasive Secondary Cytoreductive Surgery for Superficial Celiac and Cardio-Phrenic Isolated Nodal Recurrence of Ovarian Cancer.

Annals of surgical oncology

Loverro M, Ergasti R, Conte C, Gallitelli V, Nachira D, Scaglione G, Fagotti A, Scambia G, Gallotta V.
PMID: 35000090
Ann Surg Oncol. 2022 Jan 08; doi: 10.1245/s10434-021-11267-5. Epub 2022 Jan 08.

No abstract available.

Current Standards for and Clinical Impact of Emergency Radiology in Major Trauma.

International journal of environmental research and public health

Iacobellis F, Abu-Omar A, Crivelli P, Galluzzo M, Danzi R, Trinci M, Dell'Aversano Orabona G, Conti M, Romano L, Scaglione M.
PMID: 35010799
Int J Environ Res Public Health. 2022 Jan 04;19(1). doi: 10.3390/ijerph19010539.

In industrialized countries, high energy trauma represents the leading cause of death and disability among people under 35 years of age. The two leading causes of mortality are neurological injuries and bleeding. Clinical evaluation is often unreliable in determining...

PI3Kδ Sustains Keratinocyte Hyperproliferation and Epithelial Inflammation: Implications for a Topically Druggable Target in Psoriasis.

Cells

Mercurio L, Morelli M, Scarponi C, Scaglione GL, Pallotta S, Albanesi C, Madonna S.
PMID: 34685616
Cells. 2021 Oct 02;10(10). doi: 10.3390/cells10102636.

The phosphatidylinositol 3-kinase (PI3K)-dependent signaling pathway is aberrantly activated in psoriatic lesions and contributes to disease pathogenesis. Among PI3Ks enzymes, PI3Kα, β, and δ isoforms are known to bind the p85 regulatory subunit and mediate activation of AKT and...

Impact of ablation index settings on pulmonary vein reconnection.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

Lepillier A, Strisciuglio T, De Ruvo E, Scaglione M, Anselmino M, Sebag FA, Pecora D, Gallagher MM, Rillo M, Viola G, Pisanò E, Abbey S, Lamberti F, Pani A, Zucchelli G, Sgarito G, De Simone A, Bertaglia E, Solimene F, Stabile G.
PMID: 33570717
J Interv Card Electrophysiol. 2021 Feb 11; doi: 10.1007/s10840-021-00944-w. Epub 2021 Feb 11.

PURPOSE: Ablation index (AI) is a radiofrequency lesion quality marker. The AI value that allows effective and safe pulmonary vein isolation (PVI) is still debated. We evaluated the incidence of acute and late PV reconnection (PVR) with different AI...

SARS-COV-2 SCREENING IN ALLOGENEIC HEMATOPOIETIC STEM CELL DONORS: IMPLICATIONS FOR THE EVALUATION PROCESS AND ELIGIBILITY.

Hematology, transfusion and cell therapy

Crocchiolo R, Alfarano F, Volpato E, Pugliano M, Cuppari I, Mazza AM, Bellio L, Fanti D, Vismara C, Scaglione F, Sacchi N, Pollichieni S, Mele L, Diral E, Grillo G, Rossini S.
PMID: 34901751
Hematol Transfus Cell Ther. 2021 Dec 07; doi: 10.1016/j.htct.2021.09.017. Epub 2021 Dec 07.

INTRODUCTION: Soon after the onset of the SARS-CoV-2 pandemic, viral screening by nasopharyngeal swab became mandatory for allogeneic hematopoietic stem cell (HSC) donor eligibility.METHODS: We described our monocenter experience with allogeneic HSC donors from February 1 to the October...

Prognostic predictors in recurrent adult granulosa cell tumors of the ovary: a systematic review and meta-analysis.

Archives of gynecology and obstetrics

Inzani F, Santoro A, Travaglino A, D'Alessandris N, Raffone A, Straccia P, Angelico G, Arciuolo D, Scaglione G, Valente M, Tralongo P, Gallotta V, Zannoni GF.
PMID: 34799743
Arch Gynecol Obstet. 2021 Nov 19; doi: 10.1007/s00404-021-06305-2. Epub 2021 Nov 19.

BACKGROUND: Ovarian adult granulosa cell tumours are low-grade malignant sex cord-stromal neoplasm with a low recurrence rate. Prognostic factors for recurrence include tumor stage, tumor rupture in Stage I neoplasms and the presence of residual tumors after surgery. However,...

Major adverse cardiovascular events associated with VEGF-targeted anticancer tyrosine kinase inhibitors: a real-life study and proposed algorithm for proactive management.

ESMO open

Vallerio P, Orenti A, Tosi F, Maistrello M, Palazzini M, Cingarlini S, Colombo P, Bertuzzi M, Spina F, Amatu A, Lombardo R, Prata I, Scaglione F, Vighi GD, Severgnini B, Siena S, Giannattasio C, Boracchi P, Sartore-Bianchi A.
PMID: 34920290
ESMO Open. 2021 Dec 14;7(1):100338. doi: 10.1016/j.esmoop.2021.100338. Epub 2021 Dec 14.

BACKGROUND: Vascular endothelial growth factor receptor (VEGFR)-targeted tyrosine kinase inhibitors (TKIs) are widely used in cancer treatment and burdened by cardiovascular toxicity. The majority of data come from clinical trials, thus in selected populations. The aim of our study...

Combining Optogenetic Stimulation and Motor Training Improves Functional Recovery and Perilesional Cortical Activity.

Neurorehabilitation and neural repair

Conti E, Scaglione A, de Vito G, Calugi F, Pasquini M, Pizzorusso T, Micera S, Allegra Mascaro AL, Pavone FS.
PMID: 34761714
Neurorehabil Neural Repair. 2021 Nov 11;15459683211056656. doi: 10.1177/15459683211056656. Epub 2021 Nov 11.

No abstract available.

A novel smaller β-defensin-derived peptide is active against multidrug-resistant bacterial strains.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Colicchio R, Nigro E, Colavita I, Pagliuca C, Di Maro S, Tomassi S, Scaglione E, Carbone F, Carriero MV, Matarese G, Daniele A, Cosconati S, Pessi A, Salvatore F, Salvatore P.
PMID: 34818435
FASEB J. 2021 Dec;35(12):e22026. doi: 10.1096/fj.202002330RR.

Antibiotic resistance is becoming a severe obstacle in the fight against acute and chronic infectious diseases that accompany most degenerative illnesses from neoplasia to osteo-arthritis and obesity. Currently, the race is on to identify pharmaceutical molecules or combinations of...

Clear cell endometrial carcinomas with mismatch repair deficiency have a favorable prognosis: A systematic review and meta-analysis.

Gynecologic oncology

Travaglino A, Raffone A, Santoro A, Raimondo D, Angelico G, Valente M, Arciuolo D, Scaglione G, D'alessandris N, Casadio P, Inzani F, Mollo A, Seracchioli R, Zannoni GF.
PMID: 34266691
Gynecol Oncol. 2021 Sep;162(3):804-808. doi: 10.1016/j.ygyno.2021.07.007. Epub 2021 Jul 12.

INTRODUCTION: In the ESGO/ESTRO/ESP guidelines for endometrial carcinoma management, the risk category of clear cell carcinoma (CCC) is not well defined. In fact, while p53-abnormal (p53abn) CCC are known to be aggressive, the prognosis of mismatch repair-deficient (MMRd) and...

Combination of a Sindbis-SARS-CoV-2 spike vaccine and αOX40 antibody elicits protective immunity against SARS-CoV-2 induced disease and potentiates long-term SARS-CoV-2-specific humoral and T-cell immunity.

bioRxiv : the preprint server for biology

Scaglione A, Opp S, Hurtado A, Lin Z, Pampeno C, Noval MG, Thannickal SA, Stapleford KA, Meruelo D.
PMID: 34075383
bioRxiv. 2021 Jun 02; doi: 10.1101/2021.05.28.446009.

The COVID-19 pandemic caused by the coronavirus SARS-CoV-2 is a major global public threat. Currently, a worldwide effort has been mounted to generate billions of effective SARS-CoV-2 vaccine doses to immunize the world's population at record speeds. However, there...

Major adverse cardiovascular events associated with VEGF-targeted anticancer tyrosine kinase inhibitors: a real-life study and proposed algorithm for proactive management.

ESMO open

Vallerio P, Orenti A, Tosi F, Maistrello M, Palazzini M, Cingarlini S, Colombo P, Bertuzzi M, Spina F, Amatu A, Lombardo R, Prata I, Scaglione F, Vighi GD, Severgnini B, Siena S, Giannattasio C, Boracchi P, Sartore-Bianchi A.
PMID: 34920290
ESMO Open. 2021 Dec 14;7(1):100338. doi: 10.1016/j.esmoop.2021.100338. Epub 2021 Dec 14.

BACKGROUND: Vascular endothelial growth factor receptor (VEGFR)-targeted tyrosine kinase inhibitors (TKIs) are widely used in cancer treatment and burdened by cardiovascular toxicity. The majority of data come from clinical trials, thus in selected populations. The aim of our study...

Showing 13 to 24 of 209 entries